scholarly journals Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems

Micromachines ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 14
Author(s):  
Muhammad Asif Ali Rehmani ◽  
Swapna A. Jaywant ◽  
Khalid Mahmood Arif

Microfluidic devices are used to transfer small quantities of liquid through micro-scale channels. Conventionally, these devices are fabricated using techniques such as soft-lithography, paper microfluidics, micromachining, injection moulding, etc. The advancement in modern additive manufacturing methods is making three dimensional printing (3DP) a promising platform for the fabrication of microfluidic devices. Particularly, the availability of low-cost desktop 3D printers can produce inexpensive microfluidic devices in fast turnaround times. In this paper, we explore fused deposition modelling (FDM) to print non-transparent and closed internal micro features of in-plane microchannels (i.e., linear, curved and spiral channel profiles) and varying cross-section microchannels in the build direction (i.e., helical microchannel). The study provides a comparison of the minimum possible diameter size, the maximum possible fluid flow-rate without leakage, and absorption through the straight, curved, spiral and helical microchannels along with the printing accuracy of the FDM process for two low-cost desktop printers. Moreover, we highlight the geometry dependent printing issues of microchannels, pressure developed in the microchannels for complex geometry and establish that the profiles in which flowrate generates 4000 Pa are susceptible to leakages when no pre or post processing in the FDM printed parts is employed.

2014 ◽  
Vol 657 ◽  
pp. 795-799 ◽  
Author(s):  
Anastasios Chatzikonstantinou ◽  
Dimitrios Tzetzis ◽  
Panagiotis Kyratsis ◽  
Nikolaos Bilalis

The current work demonstrates a feasibility study on the generation of a copy, having a highly complex geometry, of a Greek paleontological find utilising reverse engineering and low-cost rapid prototyping techniques. A part of the jaw bone of a cave bear (Ursus spelaeus) that lived during the Pleistocene and became extinct about 10,000 years ago was digitized using a three-dimensional laser scanner. The resulting point-cloud of the scans was treated with a series of advanced software for the creation of surfaces and ultimately for a digital model. The generated model was three-dimensionally built by the aid of a Fused Deposition Modeling (FDM) apparatus. An analytical methodology is presented revealing the step by step approach from the scanning to the prototyping. It is believed that a variety of interested parties could benefit from such an analytical approach, including, production engineers, three-dimensional CAD users and designers, paleontologists and museum curators.


2009 ◽  
Vol 83-86 ◽  
pp. 269-274 ◽  
Author(s):  
Syed H. Masood ◽  
Kadhim Alamara

In tissue engineering (TE), a porous scaffold structure of biodegradable material is required as a template to guide the proliferation, growth and development of cells appropriately in three dimensions. The scaffold must meet design requirements of appropriate porosity, pore size and interconnected structure to allow cell proliferation and adhesion. This paper presents a methodology for design and manufacture of TE scaffolds with varying porosity by employing open structure building units and Fused Deposition Modeling (FDM) rapid prototyping technique. A computer modeling approach for constructing and assembly of three-dimensional unit cell structure is presented to provide a solution of scaffolds design that can potentially meet the diverse requirements of TE applications. A parametric set of open polyhedral unit cells is used to assist the user in designing the required micro-architecture of the scaffold with required porosity and pore size and then the Boolean operation is used to create the scaffold of a given CAD model from the designed microstructure. The procedure is verified by fabrication of physical scaffolds using the commercial FDM system.


ACS Omega ◽  
2020 ◽  
Vol 5 (19) ◽  
pp. 11147-11150 ◽  
Author(s):  
Dirk Volker Woortman ◽  
Martina Haack ◽  
Norbert Mehlmer ◽  
Thomas B. Brück

2021 ◽  
Vol 18 (1) ◽  
pp. 07-13
Author(s):  
Neha Thakur ◽  
Hari Murthy

Three-dimensional printing (3DP) is a digitally-controlled additive manufacturing technique used for fast prototyping. This paper reviews various 3D printing techniques like Selective Laser Sintering (SLS), Fused Deposition Modeling, (FDM), Semi-solid extrusion (SSE), Stereolithography (SLA), Thermal Inkjet (TIJ) Printing, and Binder jetting 3D Printing along with their application in the field of medicine. Normal medicines are based on the principle of “one-size-fits-all”. This is not true always, it is possible medicine used for curing one patient is giving some side effects to another. To overcome this drawback “3D Printed medicines” are developed. In this paper, 3D printed medicines forming different Active Pharmaceutical Ingredients (API) are reviewed. Printed medicines are capable of only curing the diseases, not for the diagnosis. Nanomedicines have “theranostic” ability which combines therapeutic and diagnostic. Nanoparticles are used as the drug delivery system (DDS) to damaged cells’ specific locations. By the use of nanomedicine, the fast recovery of the disease is possible. The plant-based nanoparticles are used with herbal medicines which give low-cost and less toxic medication called nanobiomedicine. 4D and 5D printing technology for the medical field are also enlightened in this paper.


2016 ◽  
Vol 835 ◽  
pp. 254-259
Author(s):  
Nor Aiman Sukindar ◽  
Mohd Khairol Anuar Mohd Ariffin

Rapid prototyping (RP) has been known as one of the advanced technology that grows tremendously over the few years. Fused Deposition Modeling (FDM) is one of the RP technologies, which is commonly used in producing three dimensional products. The study focus on the effect of dies angle in FDM nozzle and finds the optimum angle know as natural convergent angle (2θo).Polylactic acid (PLA) has been chosen as the material due to lots of advantages including biodegradability and acts as the base material for reconstructive structure for bone material. Extruding PLA material effectively is utilized under simulation method and the data obtain has been recorded. Die angle has been varied from 80o until 160o and it shows a different effect in pressure drop. Pressure drop need to be observed as it affects the road width of scaffold design, thus affecting the quality of the extruded part. The natural convergence angle (2θo) should be closed as to the die angle (2α) in order to get stability and consistency scaffold design. The natural convergent angle is found at 130o and can be considered as optimum die angle.


Scanning ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-19
Author(s):  
Yueyi Tian ◽  
ChunXu Chen ◽  
Xiaotong Xu ◽  
Jiayin Wang ◽  
Xingyu Hou ◽  
...  

Three-dimensional (3D) printing technologies are advanced manufacturing technologies based on computer-aided design digital models to create personalized 3D objects automatically. They have been widely used in the industry, design, engineering, and manufacturing fields for nearly 30 years. Three-dimensional printing has many advantages in process engineering, with applications in dentistry ranging from the field of prosthodontics, oral and maxillofacial surgery, and oral implantology to orthodontics, endodontics, and periodontology. This review provides a practical and scientific overview of 3D printing technologies. First, it introduces current 3D printing technologies, including powder bed fusion, photopolymerization molding, and fused deposition modeling. Additionally, it introduces various factors affecting 3D printing metrics, such as mechanical properties and accuracy. The final section presents a summary of the clinical applications of 3D printing in dentistry, including manufacturing working models and main applications in the fields of prosthodontics, oral and maxillofacial surgery, and oral implantology. The 3D printing technologies have the advantages of high material utilization and the ability to manufacture a single complex geometry; nevertheless, they have the disadvantages of high cost and time-consuming postprocessing. The development of new materials and technologies will be the future trend of 3D printing in dentistry, and there is no denying that 3D printing will have a bright future.


2022 ◽  
Vol 8 ◽  
Author(s):  
Charbel Tawk ◽  
Rahim Mutlu ◽  
Gursel Alici

A single universal robotic gripper with the capacity to fulfill a wide variety of gripping and grasping tasks has always been desirable. A three-dimensional (3D) printed modular soft gripper with highly conformal soft fingers that are composed of positive pressure soft pneumatic actuators along with a mechanical metamaterial was developed. The fingers of the soft gripper along with the mechanical metamaterial, which integrates a soft auxetic structure and compliant ribs, was 3D printed in a single step, without requiring support material and postprocessing, using a low-cost and open-source fused deposition modeling (FDM) 3D printer that employs a commercially available thermoplastic poly (urethane) (TPU). The soft fingers of the gripper were optimized using finite element modeling (FEM). The FE simulations accurately predicted the behavior and performance of the fingers in terms of deformation and tip force. Also, FEM was used to predict the contact behavior of the mechanical metamaterial to prove that it highly decreases the contact pressure by increasing the contact area between the soft fingers and the grasped objects and thus proving its effectiveness in enhancing the grasping performance of the gripper. The contact pressure can be decreased by up to 8.5 times with the implementation of the mechanical metamaterial. The configuration of the highly conformal gripper can be easily modulated by changing the number of fingers attached to its base to tailor it for specific manipulation tasks. Two-dimensional (2D) and 3D grasping experiments were conducted to assess the grasping performance of the soft modular gripper and to prove that the inclusion of the metamaterial increases its conformability and reduces the out-of-plane deformations of the soft monolithic fingers upon grasping different objects and consequently, resulting in the gripper in three different configurations including two, three and four-finger configurations successfully grasping a wide variety of objects.


Fused Deposition Modelling (FDM) is an innovative system that can create necessary items and are significant to generate distinctive styles of articles, in unusual supplies, completely from the uniform system. FDM machine can build fair model everything from stoneware to synthetic dolls, iron machine parts, decorative chocolate cakes or regular human body parts. FDM can supersede conventional factory industrial unit with only machinery, simply like printing press swapped by bottles of ink. Nowadays these machines are available at higher costs and are used only in industrial areas. With technology available and the material used in these machines proposes a system that sparks upon making a low cost-efficient machine and materials by designing a rigid frame for the 3D printer. The result shows low cost 3D printer prototype of FDM machine and the vibration analysis with various speed at various stages for the product outcome


2021 ◽  
Vol 22 (15) ◽  
pp. 8064
Author(s):  
Giulia Ballacchino ◽  
Edward Weaver ◽  
Essyrose Mathew ◽  
Rossella Dorati ◽  
Ida Genta ◽  
...  

Microfluidic technique has emerged as a promising tool for the production of stable and monodispersed nanoparticles (NPs). In particular, this work focuses on liposome production by microfluidics and on factors involved in determining liposome characteristics. Traditional fabrication techniques for microfluidic devices suffer from several disadvantages, such as multistep processing and expensive facilities. Three-dimensional printing (3DP) has been revolutionary for microfluidic device production, boasting facile and low-cost fabrication. In this study, microfluidic devices with innovative micromixing patterns were developed using fused deposition modelling (FDM) and liquid crystal display (LCD) printers. To date, this work is the first to study liposome production using LCD-printed microfluidic devices. The current study deals with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes with cholesterol (2:1) prepared using commercial and 3D-printed microfluidic devices. We evaluated the effect of microfluidic parameters, chip manufacturing, material, and channel design on liposomal formulation by analysing the size, PDI, and ζ-potential. Curcumin exhibits potent anticancer activity and it has been reported that curcumin-loaded liposomes formulated by microfluidics show enhanced encapsulation efficiency when compared with other reported systems. In this work, curcumal liposomes were produced using the developed microfluidic devices and particle sizing, ζ-potential, encapsulation efficiency, and in vitro release studies were performed at 37 °C.


Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3879
Author(s):  
Anna C. Tasolamprou ◽  
Despoina Mentzaki ◽  
Zacharias Viskadourakis ◽  
Eleftherios N. Economou ◽  
Maria Kafesaki ◽  
...  

In this work we present a method for fabricating three dimensional, ultralight and flexible millimeter metamaterial units using a commercial household 3D printer. The method is low-cost, fast, eco-friendly and accessible. In particular, we use the Fused Deposition Modeling 3D printing technique and we fabricate flexible conductive Spilt Ring Resonators (SRRs) in a free-standing form. We characterized the samples experimentally through measurements of their spectral transmission, using standard rectangular microwave waveguides. Our findings show that the resonators produce well defined resonant electromagnetic features that depend on the structural details and the infiltrating dielectric materials, indicating that the thin, flexible and light 3D printed structures may be used as electromagnetic microwave components and electromagnetic fabrics for coating a variety of devices and infrastructure units, while adapting to different shapes and sizes.


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