scholarly journals Special Issue: Bacteriophage Treatment as an Alternative Technology to Inactivate Pathogenic Bacteria: A Generalized Worldwide Growing Acceptance

2021 ◽  
Vol 10 (1) ◽  
pp. 12
Author(s):  
Adelaide Almeida
Keyword(s):  
Antibiotic Resistance ◽  
Wastewater Treatment ◽  
Veterinary Medicine ◽  
Bacterial Infections ◽  
Pathogenic Bacteria ◽  
Human Medicine ◽  
Alternative Methods ◽  
Special Issue ◽  
Alternative Technology

The increasing worldwide rate of antibiotic resistance has led to a higher incidence of bacterial infections that require alternative methods for their control not only in human medicine, but also in other areas, such as in veterinary medicine, agro-food field and wastewater treatment [...]

scholarly journals Phages as a Cohesive Prophylactic and Therapeutic Approach in Aquaculture Systems

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 564 ◽  
Author(s):  
Maciej Żaczek ◽  
Beata Weber-Dąbrowska ◽  
Andrzej Górski
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Infections ◽  
Pathogenic Bacteria ◽  
Human Life ◽  
Natural Habitat ◽  
Aquatic Organisms ◽  
Economic Losses ◽  
Complex Approach ◽  
Promising Solution ◽  
Phage Treatment

Facing antibiotic resistance has provoked a continuously growing focus on phage therapy. Although the greatest emphasis has always been placed on phage treatment in humans, behind phage application lies a complex approach that can be usefully adopted by the food industry, from hatcheries and croplands to ready-to-eat products. Such diverse businesses require an efficient method for combating highly pathogenic bacteria since antibiotic resistance concerns every aspect of human life. Despite the vast abundance of phages on Earth, the aquatic environment has been considered their most natural habitat. Water favors multidirectional Brownian motion and increases the possibility of contact between phage particles and their bacterial hosts. As the global production of aquatic organisms has rapidly grown over the past decades, phage treatment of bacterial infections seems to be an obvious and promising solution in this market sector. Pathogenic bacteria, such as Aeromonas and Vibrio, have already proved to be responsible for mass mortalities in aquatic systems, resulting in economic losses. The main objective of this work is to summarize, from a scientific and industry perspective, the recent data regarding phage application in the form of targeted probiotics and therapeutic agents in aquaculture niches.

scholarly journals Swedres 2003: report on Swedish antibiotic utilisation and resistance in human medicine

2004 ◽  
Vol 8 (27) ◽  
Author(s):  
K Lundh ◽  
Keyword(s):  
Antibiotic Resistance ◽  
Veterinary Medicine ◽  
Human Medicine ◽  
Close Collaboration

There has been close collaboration between human and veterinary medicine regarding antibiotic resistance for several years in Sweden

Antibiotic resistance and alternative methods of prevention and control of bacterial infections

2021 ◽  
Vol 24 (5) ◽  
pp. 30-34
Author(s):  
S.V. Engashev ◽  
◽  
A.A. Gusev ◽  
E.S. Engasheva ◽  
V.A. Babak ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Prevention And Control ◽  
Bacterial Infections ◽  
Alternative Methods ◽  
And Control

scholarly journals Potential of Nanoparticles Integrated with Antibacterial Properties in Preventing Biofilm and Antibiotic Resistance

Antibiotics ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1338
Author(s):  
Maheswary Thambirajoo ◽  
Manira Maarof ◽  
Yogeswaran Lokanathan ◽  
Haliza Katas ◽  
Nur Fatiha Ghazalli ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Antibacterial Properties ◽  
Alternative Methods ◽  
Bacterial Biofilms ◽  
High Morbidity ◽  
Different Types ◽  
Other Substances ◽  
Potential Use

Nanotechnology has become an emerging technology in the medical field and is widely applicable for various clinical applications. The potential use of nanoparticles as antimicrobial agents is greatly explored and taken into consideration as alternative methods to overcome the challenges faced by healthcare workers and patients in preventing infections caused by pathogenic microorganisms. Among microorganisms, bacterial infections remain a major hurdle and are responsible for high morbidity and mortality globally, especially involving those with medical conditions and elderly populations. Over time, these groups are more vulnerable to developing resistance to antibiotics, as bacterial biofilms are difficult to destroy or eliminate via antibiotics; thus, treatment becomes unsuccessful or ineffective. Mostly, bacterial biofilms and other microbes can be found on medical devices and wounds where they disperse their contents which cause infections. To inhibit biofilm formations and overcome antibiotic resistance, antimicrobial-loaded nanoparticles alone or combined with other substances could enhance the bactericidal activity of nanomaterials. This includes killing the pathogens effectively without harming other cells or causing any adverse effects to living cells. This review summarises the mechanisms of actions employed by the different types of nanoparticles which counteract infectious agents in reducing biofilm formation and improve antibiotic therapy for clinical usage.

PROSPECTS FOR THE USE OF SPECIFIC YOLK IMMUNOGLOBULIN CHICKENS FOR THE TREATMENT AND PREVENTION OF BACTERIAL INFECTIONS OF ANIMALS AND BIRDS (REVIEW)

2021 ◽  
pp. 22-26
Author(s):  
S. S. Koypish
Keyword(s):  
Veterinary Medicine ◽  
Bacterial Infections ◽  
Human Medicine ◽  
Treatment And Prevention ◽  
The Republic

The article presents data on the perspective and results of the use of specific yolk immunoglobulins IgY of chickens in veterinary medicine and human medicine, which are relevant for use in the Republic of Belarus.

scholarly journals Valorization of Winemaking By-Products as a Novel Source of Antibacterial Properties: New Strategies to Fight Antibiotic Resistance

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2331
Author(s):  
Adriana Silva ◽  
Vanessa Silva ◽  
Gilberto Igrejas ◽  
Isabel Gaivão ◽  
Alfredo Aires ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Bacterial Infections ◽  
Pathogenic Bacteria ◽  
Bacterial Resistance ◽  
Combined Therapy ◽  
Antibacterial Properties ◽  
Global Scale ◽  
Wine Industry ◽  
Alternative Solutions ◽  
By Products

The emergence of antibiotic-resistance in bacteria has limited the ability to treat bacterial infections, besides increasing their morbidity and mortality at the global scale. The need for alternative solutions to deal with this problem is urgent and has brought about a renewed interest in natural products as sources of potential antimicrobials. The wine industry is responsible for the production of vast amounts of waste and by-products, with associated environmental problems. These residues are rich in bioactive secondary metabolites, especially phenolic compounds. Some phenolics are bacteriostatic/bactericidal against several pathogenic bacteria and may have a synergistic action towards antibiotics, mitigating or reverting bacterial resistance to these drugs. Complex phenolic mixtures, such as those present in winemaking residues (pomace, skins, stalks, leaves, and especially seeds), are even more effective as antimicrobials and could be used in combined therapy, thereby contributing to management of the antibiotic resistance crisis. This review focuses on the potentialities of winemaking by-products, their extracts, and constituents as chemotherapeutic antibacterial agents.

scholarly journals Veteriner Hekimlikte Kulak, Burun, Boğaz Alanında Kullanılan Antiseptikler

2020 ◽  
Vol 8 (5) ◽  
pp. 1083-1089
Author(s):  
Hür Can Tümay ◽  
Ayhan Filazi
Keyword(s):  
Antibiotic Resistance ◽  
Veterinary Medicine ◽  
Bacterial Resistance ◽  
Human Medicine ◽  
Multiple Antibiotic Resistance ◽  
Treatment Methods ◽  
Nose And Throat ◽  
Ent Disorders

Although the studies on ear, nose and throat (ENT) diseases and treatment methods are high in human medicine, they are rarely performed and neglected in veterinary medicine. Antibiotics are generally preferred for ENT diseases in animals. However, there is an increase in infections from microorganisms that develop multiple antibiotic resistance due to overuse and misuse of antibiotics. Another group of drugs used in ENT diseases are antiseptics. Bacterial resistance to agents used as antiseptics is more limited than antibiotics. Studies on the use of substances with antiseptic properties in the treatment of ENT disorders in animals have been limited. Even though these substances are used empirically in the field, there are no studies in the literature examining the effects of these substances on ENT. In this review, the properties of antiseptic substances recommended for use in the field and in the literature for ENT diseases of animals are discussed.

scholarly journals Sewage-Borne Pathogens and Indigenous Denitrifiers are Active and Key Multi-Antibiotic Resistant Players in Wastewater Treatment Plants

2020 ◽  
Author(s):  
Ling Yuan ◽  
Yubo Wang ◽  
Lu Zhang ◽  
Alejandro Palomo ◽  
Jizhong Zhou ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Wastewater Treatment ◽  
Health Risks ◽  
Bacterial Infections ◽  
Wastewater Treatment Plants ◽  
Antibiotic Resistance Genes ◽  
Emerging Pathogens ◽  
Aminoglycoside Resistance ◽  
Antibiotic Resistant ◽  
Genome Level

AbstractThe global rise and environmental spread of antibiotic resistance greatly challenge the treatment of deadly bacterial infections. Wastewater treatment plants (WWTPs) harbor and discharge antibiotic resistance genes (ARGs) as emerging environmental contaminants. However, the knowledge gap on the host identity and functionality limits rational assessment of transmission and health risks of ARGs emitted from WWTPs to the environment. Here, we developed an innovative genome-centric quantitative metatranscriptomic approach that breaks existing methodological limitations by integrating genome-level taxonomy and activity-based analyses to realize high-resolution qualitative and quantitative analyses of bacterial hosts of ARGs (i.e., multi-resistance, pathogenicity, activity and niches) throughout 12 urban WWTPs. We found that ∼45% of 248 population genomes recovered actively expressed resistance against multiple classes of antibiotics, among which bacitracin and aminoglycoside resistance in Proteobacteria was the most prevalent. Both sewage-borne pathogens and indigenous denitrifying bacteria were transcriptionally active ARG hosts, contributing ∼60% of detected resistance activities. Remarkably, eighteen antibiotic-resistant pathogens from the influent survived wastewater treatment, indicating their potential roles as persistent and clinically relevant resistance disseminators. The prevalence of ARGs in most transcriptionally active denitrifying populations (∼90%) may suggest their adaptation to local metabolic niches and antimicrobial stressors. While wastewater treatment dramatically reduced the absolute expression activities of ARGs (> 99%), their relative expression levels remained almost unchanged in the majority of resistant populations. The prevalence of active ARG hosts including globally emerging pathogens (e.g., A. cryaerophilus) throughout and across WWTPs prioritizes future examination on the health risks related with resistance propagation and human exposure in the receiving environment.

scholarly journals The occurrence of specific markers of Bacteroides fragilis group, B. dorei and antibiotic-resistance genes in the wastewater treatment plants

2018 ◽  
Vol 44 ◽  
pp. 00124
Author(s):  
Sebastian Niestępski ◽  
Monika Harnisz ◽  
Ewa Korzeniewska ◽  
Adriana Osińska
Keyword(s):  
Antibiotic Resistance ◽  
Wastewater Treatment ◽  
Resistance Genes ◽  
Pathogenic Bacteria ◽  
Wastewater Treatment Plants ◽  
Genetic Material ◽  
Bacteroides Fragilis ◽  
Antibiotic Resistance Genes ◽  
Genes Encoding ◽  
Wastewater Samples

Wastewater treatment plants (WWTPs) are one of the main transmission sources of pathogenic bacteria and antibiotic-resistance genes in the natural environment. In this study, the presence of specific markers of Bacteroides fragilis group (BFG), B. dorei and genes encoding resistance to beta-lactams (cepA, cfxA), tetracyclines (tet(Q)), macrolides, lincosamides and streptogramins (MLS) mechanism (ermF, linA) was analyzed by standard PCR in the inflows and outflows from three wastewater treatment plants with the activated sludge process. Genetic material was isolated from wastewater samples with the use of two commercial kits for genomic DNA extraction, the Fast DNA SPIN Kit for Soil and the Genomic Micro AX Bacteria Gravity Kit. The quality of the isolated genetic material differed between the tested isolation kits. The Fast DNA SPIN Kit for Soil was more effective in detecting cfxA, ermF and linA genes. However, both extraction kits effectively identified tet(Q), bfr and HF183/BacR287 genes in all wastewater samples. The results of the study indicate that genes specific to BFG and B. dorei, and genes encoding resistance to MLS and tetracyclines are not completely eliminated during the wastewater treatment process.

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