scholarly journals The Dynamics of Hole Transfer in DNA

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4044 ◽  
Author(s):  
Andrea Peluso ◽  
Tonino Caruso ◽  
Alessandro Landi ◽  
Amedeo Capobianco
Keyword(s):  
High Energy ◽  
Hole Transport ◽  
Charge Hole ◽  
Hole Transfer ◽  
High Energy Radiation ◽  
Specific Effects ◽  
Redox Sensing ◽  
Hole Migration ◽  
Kinetics Of ◽  
Disease Understanding

High-energy radiation and oxidizing agents can ionize DNA. One electron oxidation gives rise to a radical cation whose charge (hole) can migrate through DNA covering several hundreds of Å, eventually leading to irreversible oxidative damage and consequent disease. Understanding the thermodynamic, kinetic and chemical aspects of the hole transport in DNA is important not only for its biological consequences, but also for assessing the properties of DNA in redox sensing or labeling. Furthermore, due to hole migration, DNA could potentially play an important role in nanoelectronics, by acting as both a template and active component. Herein, we review our work on the dynamics of hole transfer in DNA carried out in the last decade. After retrieving the thermodynamic parameters needed to address the dynamics of hole transfer by voltammetric and spectroscopic experiments and quantum chemical computations, we develop a theoretical methodology which allows for a faithful interpretation of the kinetics of the hole transport in DNA and is also capable of taking into account sequence-specific effects.

Photo-degradation of monoazo dye blue 13 using advanced oxidation process

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Aqueous Solution ◽  
Advanced Oxidation Process ◽  
Oxidation Process ◽  
High Energy ◽  
Uv Exposure ◽  
H2o2 Concentration ◽  
Oxidizing Agent ◽  
Photo Degradation ◽  
High Energy Radiation ◽  
Uv Lamp

The high energy radiation overcome the bonding of solute in a solution and H2O2 acts as an oxidizing agent and generates a free radical in the solution which results in photo-degradation by converting the solute in to simple form and resultantly, colored substance under the effect of photo-degradation becomes colorless. The photo-degradation of monoazo dye Blue 13 in an aqueous solution was investigated using a laboratory scale UV lamp in the presence of H2O2 and for maximum degradation of dye, the independent parameter UV power, UV exposure time, pH and H2O2 concentration were optimized. It was found that neither UV in the presence of H2O2 is able to degrade Blue 13 under optimum condition. The results revealed that the use of both UV and H2O2 have pronounced effect on the discoloration of dyes which could be used for management of textile effluents contain waste dyes.

scholarly journals Challenges and Opportunities for CsPbBr3 Perovskites in Low- and High-Energy Radiation Detection

2021 ◽  
pp. 1290-1314
Author(s):  
Lotte Clinckemalie ◽  
Donato Valli ◽  
Maarten B. J. Roeffaers ◽  
Johan Hofkens ◽  
Bapi Pradhan ◽  
...  
Keyword(s):  
Radiation Detection ◽  
High Energy ◽  
High Energy Radiation ◽  
Energy Radiation ◽  
Challenges And Opportunities

scholarly journals Signatures of the Carrier Envelope Phase in Nonlinear Thomson Scattering

Crystals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 528
Author(s):  
Marcel Ruijter ◽  
Vittoria Petrillo ◽  
Thomas C. Teter ◽  
Maksim Valialshchikov ◽  
Sergey Rykovanov
Keyword(s):  
Laser Pulse ◽  
Radiation Spectrum ◽  
Thomson Scattering ◽  
High Energy ◽  
Phase Changes ◽  
High Energy Radiation ◽  
Carrier Envelope Phase ◽  
High Intensity Laser ◽  
Experimental Parameters ◽  
Intensity Laser

High-energy radiation can be generated by colliding a relativistic electron bunch with a high-intensity laser pulse—a process known as Thomson scattering. In the nonlinear regime the emitted radiation contains harmonics. For a laser pulse whose length is comparable to its wavelength, the carrier envelope phase changes the behavior of the motion of the electron and therefore the radiation spectrum. Here we show theoretically and numerically the dependency of the spectrum on the intensity of the laser and the carrier envelope phase. Additionally, we also discuss what experimental parameters are required to measure the effects for a beamed pulse.

Ultrasmall Gd@Cdots as a Radiosensitizing Agent for Non-Small Cell Lung Cancer

Nanoscale ◽  
2021 ◽  
Author(s):  
Chaebin Lee ◽  
Xiangji Liu ◽  
Weizhong Zhang ◽  
M. A. Duncan ◽  
Fangchao Jiang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cross Section ◽  
Cell Lung Cancer ◽  
High Energy ◽  
Small Cell ◽  
Small Cell Lung ◽  
High Energy Radiation ◽  
Energy Radiation

High-Z nanoparticles (HZNPs) afford high cross-section for high energy radiation and have attracted wide attention as a novel type of radiosensizers. However, conventional HZNPs are often associated with issues such...

scholarly journals Recent advances in radiation detection technologies enabled by metal-halide perovskites

2021 ◽  
Author(s):  
Tiebin Yang ◽  
Feng Li ◽  
Rongkun Zheng
Keyword(s):  
Gamma Rays ◽  
Performance Optimization ◽  
Radiation Detection ◽  
High Energy ◽  
Device Performance ◽  
High Energy Radiation ◽  
Energy Radiation ◽  
Halide Perovskites ◽  
Alpha Beta ◽  
Detection Technologies

Perovskite halides hold great potential for high-energy radiation detection. Recent advancements in detecting alpha-, beta-, X-, and gamma-rays by perovskite halides are reviewed and an outlook on the device performance optimization is provided.

scholarly journals The interstellar medium in young supernova remnants: key to the production of cosmic X-rays and $\gamma $-rays

2021 ◽  
Vol 366 (6) ◽  
Author(s):  
Hidetoshi Sano ◽  
Yasuo Fukui
Keyword(s):  
Interstellar Medium ◽  
Supernova Remnants ◽  
Cosmic Ray ◽  
High Energy ◽  
X Rays ◽  
Interstellar Gas ◽  
High Energy Radiation ◽  
Dense Cores ◽  
The Relationship ◽  
Turbulent Velocity Field

AbstractWe review recent progress in elucidating the relationship between high-energy radiation and the interstellar medium (ISM) in young supernova remnants (SNRs) with ages of ∼2000 yr, focusing in particular on RX J1713.7−3946 and RCW 86. Both SNRs emit strong nonthermal X-rays and TeV $\gamma $ γ -rays, and they contain clumpy distributions of interstellar gas that includes both atomic and molecular hydrogen. We find that shock–cloud interactions provide a viable explanation for the spatial correlation between the X-rays and ISM. In these interactions, the supernova shocks hit the typically pc-scale dense cores, generating a highly turbulent velocity field that amplifies the magnetic field up to 0.1–1 mG. This amplification leads to enhanced nonthermal synchrotron emission around the clumps, whereas the cosmic-ray electrons do not penetrate the clumps. Accordingly, the nonthermal X-rays exhibit a spatial distribution similar to that of the ISM on the pc scale, while they are anticorrelated at sub-pc scales. These results predict that hadronic $\gamma $ γ -rays can be emitted from the dense cores, resulting in a spatial correspondence between the $\gamma $ γ -rays and the ISM. The current pc-scale resolution of $\gamma $ γ -ray observations is too low to resolve this correspondence. Future $\gamma $ γ -ray observations with the Cherenkov Telescope Array will be able to resolve the sub-pc-scale $\gamma $ γ -ray distribution and provide clues to the origin of these cosmic $\gamma $ γ -rays.

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