scholarly journals Much More Than a Pleasant Scent: A Review on Essential Oils Supporting the Immune System

Molecules ◽  
2019 ◽  
Vol 24 (24) ◽  
pp. 4530 ◽  
Author(s):  
Agnes Peterfalvi ◽  
Eva Miko ◽  
Tamas Nagy ◽  
Barbara Reger ◽  
Diana Simon ◽  
...  
Keyword(s):  
Essential Oils ◽  
Immune Function ◽  
Scientific Data ◽  
Herbal Products ◽  
Plant Essential Oils ◽  
Routes Of Administration ◽  
Pubmed Database ◽  
Cumulative Evidence

The augmenting acceptance and application of herbal medicine in prevention and treatment of diseases also involve the use of plant essential oils (EOs) through different routes of administration (aromatherapy). Scientific data supporting the efficacy of certain herbal products are continuously growing; however, the cumulative evidence is not always sufficient. The anti-inflammatory properties of EOs have been investigated more extensively and also reviewed in different settings, but so far, our review is the first to summarize the immune-supporting properties of EOs. Our aim here is to synthesize the currently available data on the immune function enhancing effects of EOs. An online search was conducted in the PubMed database, which was terminated at the end of July 2019. Other articles were found in the reference lists of the preselected papers. Studies that applied whole EOs with known components, or single EO constituents under in vitro or in vivo laboratory conditions, or in human studies, and de facto measured parameters related to immune function as outcome measures were included. Two specific fields, EO dietary supplementation for livestock and fish, and forest bathing are also explored. Some EOs, particularly eucalyptus and ginger, seem to have immune function enhancing properties in multiple studies.

scholarly journals Essential Oils in Livestock: From Health to Food Quality

Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 330
Author(s):  
Ralph Nehme ◽  
Sonia Andrés ◽  
Renato B. Pereira ◽  
Meriem Ben Jemaa ◽  
Said Bouhallab ◽  
...  
Keyword(s):  
Essential Oils ◽  
Antioxidant Activities ◽  
Animal Health ◽  
Antioxidant Properties ◽  
Scientific Data ◽  
Plant Essential Oils ◽  
Anti Inflammatory ◽  
And Performance

Using plant essential oils (EOs) contributes to the growing number of natural plants’ applications in livestock. Scientific data supporting the efficacy of EOs as anti-inflammatory, antibacterial and antioxidant molecules accumulates over time; however, the cumulative evidence is not always sufficient. EOs antioxidant properties have been investigated mainly from human perspectives. Still, so far, our review is the first to combine the beneficial supporting properties of EOs in a One Health approach and as an animal product quality enhancer, opening new possibilities for their utilization in the livestock and nutrition sectors. We aim to compile the currently available data on the main anti-inflammatory effects of EOs, whether encapsulated or not, with a focus on mammary gland inflammation. We will also review the EOs’ antioxidant activities when given in the diet or as a food preservative to counteract oxidative stress. We emphasize EOs’ in vitro and in vivo ruminal microbiota and mechanisms of action to promote animal health and performance. Given the concept of DOHaD (Developmental Origin of Health and Diseases), supplementing animals with EOs in early life opens new perspectives in the nutrition sector. However, effective evaluation of the significant safety components is required before extending their use to livestock and veterinary medicine.

In vivo and in vitro control activity of plant essential oils against three strains of Aspergillus niger

2017 ◽  
Vol 24 (27) ◽  
pp. 21948-21959 ◽  
Author(s):  
Peeyush Kumar ◽  
Sapna Mishra ◽  
Atul Kumar ◽  
Sanjeev Kumar ◽  
Chandra Shekhar Prasad
Keyword(s):  
Aspergillus Niger ◽  
Essential Oils ◽  
Control Activity ◽  
Plant Essential Oils

scholarly journals Plant essential oils against bacteria isolated from fish: an in vitro screening and in vivo efficacy of Lippia origanoides

2019 ◽  
Vol 49 (6) ◽  
Author(s):  
Guerino Bandeira Junior ◽  
Carine de Freitas Souza ◽  
Matheus Dellaméa Baldissera ◽  
Sharine Nunes Descovi ◽  
Bibiana Petri da Silveira ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Essential Oils ◽  
Bacterial Infections ◽  
Cupressus Sempervirens ◽  
Therapeutic Success ◽  
Plant Essential Oils ◽  
In Vitro Antibacterial Activity ◽  
Fish Bacteria

ABSTRACT: The use of natural products, such as essential oils (EOs), is a potential novel approach to treat fish bacterial infections with a lower risk of developing resistance. There has been a number of studies reporting the activity of EOs as those obtained from the species Achyrocline satureioides, Aniba parviflora, Aniba rosaeodora, Anthemis nobilis, Conobea scoparioides, Cupressus sempervirens, Illicium verum, Lippia origanoides, and Melaleuca alternifolia against bacteria. However, there are few studies investigating the effect of these EOs against fish bacteria. Therefore, the aim of this study was to evaluate the in vitro antibacterial activity of EOs against the following fish bacteria, Aeromonas hydrophila, Citrobacter freundii, and Raoultella ornithinolytica. Additionally, the in vivo antibacterial activity of the EO L. origanoides was evaluated against experimentally induced A. hydrophila infection of silver catfish (Rhamdia quelen). The EO of L. origanoides was chosen as it showed the highest in vitro antibacterial activity, with minimum inhibitory concentrations ranging from 0.2 to 0.8 mg mL-1. This EO also presented a therapeutic success of 58.33%, on a 30 day A. hydrophila infection. Therefore, we suggested that the EO of L. origanoides may be a viable alternative as a treatment for A. hydrophila infection.

HuR as Therapeutic Target in Cancer: What the Future Holds

2021 ◽  
Vol 28 ◽  
Author(s):  
Dimitrios Goutas ◽  
Alexandros Pergaris ◽  
Constantinos Giaginis ◽  
Stamatios Theocharis
Keyword(s):  
Therapeutic Target ◽  
Rna Binding ◽  
Cancer Therapeutics ◽  
Scientific Data ◽  
Promising Target ◽  
Pubmed Database ◽  
Increased Risk ◽  
Major Player

: ELAV-like protein 1, or HuR (human antigen R), is an RNA-binding protein encoded by the ELAVL1 gene in humans. One of its best functions is to stabilize mRNAs in order to regulate gene expression. HuR protein overexpression has undoubtedly been linked to an increased risk of tumor growth, progression, and metastasis, rendering it a potential therapeutic target candidate in cancer. Novel agents interfering with HuR expression have been tested, both in vitro and in vivo, with promising results. The aim of this paper is to review the existing literature regarding the potential agents that could actively act on and inhibit HuR expression. HuR molecule controls the expression of various proto-oncogenes, cytokines and growth factors, representing a major player in tumor progression, invasion, and metastasis and constituting an emerging target for cancer therapy. PubMed database was thoroughly searched, and all published articles providing scientific data on molecules that can exhibit antitumorigenic effects via HuR inhibition were included. According to these data, HuR inhibition should be a promising target in cancer therapeutics.

scholarly journals In vivo efficacy of carvacrol on Campylobacter jejuni prevalence in broiler chickens during an entire fattening period

2020 ◽  
Vol 10 (3) ◽  
pp. 131-138
Author(s):  
V. Szott ◽  
B. Reichelt ◽  
T. Alter ◽  
A. Friese ◽  
U. Roesler
Keyword(s):  
Essential Oils ◽  
Campylobacter Jejuni ◽  
Broiler Chickens ◽  
Most Probable Number ◽  
Resistant Bacteria ◽  
Probable Number ◽  
Plant Essential Oils ◽  
Fattening Period

AbstractCarvacrol, a primary constituent of plant essential oils (EOs), and its antimicrobial activity have been the subject of many in vitro studies. Due to an increasing demand for alternative antimicrobials and an emerging number of antibiotic resistant bacteria, the use of essential oils has played a major role in many recent approaches to reduce Campylobacter colonization in poultry before slaughter age. For that purpose, the reducing effect of carvacrol on Campylobacter jejuni prevalence in broilers was determined in vivo in an experimental broiler chicken model during an entire fattening period. Carvacrol was added to the feed in a concentration of 120 mg/kg feed four days post hatch until the end of the trial. In this study, we demonstrated a statistically significant decrease of C. jejuni counts by 1.17 decadic logarithm (log10) most probable number (MPN)/g in cloacal swabs during starter and grower periods (corresponding to a broilers age between 1 and 28 days). Similar results were observed for colon enumeration at the end of the trial where C. jejuni counts were significantly reduced by 1.25 log10 MPN/g. However, carvacrol did not successfully reduce Campylobacter cecal colonization in 33-day-old broilers.

Activities of essential oils from three Brazilian plants and benzaldehyde analogues against Meloidogyne incognita

Nematology ◽  
2019 ◽  
Vol 21 (10) ◽  
pp. 1081-1089 ◽  
Author(s):  
Aline Ferreira Barros ◽  
Vicente Paulo Campos ◽  
Denilson Ferreira de Oliveira ◽  
Fabiola de Jesus Silva ◽  
Iselino Nogueira Jardim ◽  
...  
Keyword(s):  
Essential Oils ◽  
Meloidogyne Incognita ◽  
Parasitic Nematodes ◽  
Plant Parasitic Nematodes ◽  
Plant Essential Oils ◽  
Hyptis Suaveolens ◽  
Stage Juvenile ◽  
Main Component

Summary There is a demand for novel products for the control of plant-parasitic nematodes, so we characterised the effectiveness of some plant essential oils against Meloidogyne incognita and verified the efficiency of the major component from the most toxic oils and their analogues using in vitro and in vivo assays. In this study, the essential oils from Piptadenia viridiflora, Hyptis suaveolens and Astronium graveolens against M. incognita were evaluated, but only P. viridiflora oil showed toxicity toward M. incognita. Benzaldehyde was its main component according to GC-MS analysis. In in vitro assays, benzaldehyde (100 and 200 μg ml−1) and its oxime (400 μg ml−1) caused a higher rate of M. incognita second-stage juvenile (J2) mortality than the nematicide carbofuran (170 μg ml−1). Reductions of more than 90% in the number of galls and eggs, even greater than that observed with carbofuran, were observed in the assay where the J2 were placed in solutions of benzaldehyde and its oxime 48 h prior to tomato plant inoculation. Application of benzaldehyde together with M. incognita J2 to the substrate resulted only in a reduction in the number of eggs (42-65%); however, its oxime reduced both the number of galls (43-84%) and eggs (23-89%). Therefore, the P. viridiflora oil, its major component benzaldehyde, and the analogue benzaldehyde oxime are toxic to M. incognita. In two different in vivo assays, benzaldehyde oxime was confirmed as toxic to M. incognita with a greater efficacy than benzaldehyde.

scholarly journals Antiparasitic and Antibacterial Functionality of Essential Oils: An Alternative Approach for Sustainable Aquaculture

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 185 ◽  
Author(s):  
Mahmoud A. O. Dawood ◽  
Mohammed F. El Basuini ◽  
Amr I. Zaineldin ◽  
Sevdan Yilmaz ◽  
Md. Tawheed Hasan ◽  
...  
Keyword(s):  
Essential Oils ◽  
Pathogenic Bacteria ◽  
Aquatic Organisms ◽  
Aeromonas Salmonicida ◽  
Fish Parasites ◽  
Sustainable Aquaculture ◽  
Herbal Products ◽  
Hydrophobic Compounds

Using synthetic antibiotics/chemicals for infectious bacterial pathogens and parasitic disease control causes beneficial microbial killing, produces multi-drug resistant pathogens, and residual antibiotic impacts in humans are the major threats to aquaculture sustainability. Applications of herbal products to combat microbial and parasitic diseases are considered as alternative approaches for sustainable aquaculture. Essential oils (EOs) are the secondary metabolites of medicinal plants that possess bioactive compounds like terpens, terpenoids, phenylpropenes, and isothiocyanates with synergistic relationship among these compounds. The hydrophobic compounds of EOs can penetrate the bacterial and parasitic cells and cause cell deformities and organelles dysfunctions. Dietary supplementation of EOs also modulate growth, immunity, and infectious disease resistance in aquatic organisms. Published research reports also demonstrated EOs effectiveness against Ichthyophthirius multifiliis, Gyrodactylus sp., Euclinostomum heterostomum, and other parasites both in vivo and in vitro. Moreover, different infectious fish pathogenic bacteria like Aeromonas salmonicida, Vibrio harveyi, and Streptococcus agalactiae destruction was confirmed by plant originated EOs. However, no research was conducted to confirm the mechanism of action or pathway identification of EOs to combat aquatic parasites and disease-causing microbes. This review aims to explore the effectiveness of EOs against fish parasites and pathogenic bacteria as an environment-friendly phytotherapeutic in the aquaculture industry. Moreover, research gaps and future approaches to use EOs for sustainable aquaculture practice are also postulated.

scholarly journals Antifungal Activity of Plant Essential Oils Against Botrytis cinerea, Penicillium italicum and Penicillium digitatum

2013 ◽  
Vol 41 (1) ◽  
pp. 86 ◽  
Author(s):  
Andrew VITORATOS ◽  
Dimitrios BILALIS ◽  
Anestis KARKANIS ◽  
Aspasia EFTHIMIADOU
Keyword(s):  
Essential Oils ◽  
Botrytis Cinerea ◽  
Disease Severity ◽  
Grey Mould ◽  
Penicillium Italicum ◽  
Postharvest Diseases ◽  
Mycelium Growth ◽  
Plant Essential Oils

Plant essential oils have the potential to replace the synthetic fungicides in the management of postharvest diseases of fruit and vegetables.The aim of this study was to access the in vitro and in vivo activity of essential oil obtained from oregano (Origanum vulgare L. ssp. hirtum), thyme (Thymus vulgaris L.) and lemon (Citrus limon L.) plants, against some important postharvest pathogens (Botrytis cinerea, Penicillium italicum and P. digitatum). In vitro experiments indicated that P. italicum did not show any mycelium growth in presence of thyme essential oils at concentration of 0.13 μl/ml. Moreover, B. cinerea did not show any mycelium growth in presence of lemon and oregano essential oils at concentration of 17 μl/ml and 0.02 μl/ml, respectively. Moreover, the essential oils from three species were effective in reducing the spore germination. The in vivo experiments confirmed the strong efficacy shown in vitro by essential oils. These oregano and lemon oils were very effective in controlling disease severity of infected fruit by B. cinera in tomatoes, strawberries and cucumbers. In tomatoes, grey mould due to B. cinerea was completed inhibited by oregano essential oils at 0.30 μl/ml. Moreover, lemon essential oils induced a significant reduction of grey mould disease severity. In strawberries, grey mould was completed inhibited by lemon essential oils at 0.05 μl/ml. In addition, lemon essential oils at 0.05 μl/ml showed 39% reduction of infected cucumber fruits by B. cinerea. These results indicate that essential oils after suitable formulation could be used for the control of postharvest diseases caused by Botrytis and Penicillium pathogens.

scholarly journals Physical characteristics, chemical compositions, and insecticidal activity of plant essential oils against chicken lice (Menopon gallinae) and mites (Ornithonyssus bursa)

2021 ◽  
Vol 19 (3) ◽  
pp. 449-466
Author(s):  
Nattha Vigad ◽  
◽  
Wattana Pelyuntha ◽  
Prapakorn Tarachai ◽  
Sunee Chansakaow ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Chemical Constituents ◽  
Chemical Compositions ◽  
Plant Essential Oils ◽  
Citronella Oil ◽  
Animal Trials ◽  
Ornithonyssus Bursa

A preparation of essential oils to control chicken lice (Menopon gallinae) and mites (Ornithonyssus bursa) was developed. Each essential oil was effective against lice and mite in vitro. Citronella oil at the lowest concentration of 0.208 µg/cm2 resulted in a mortality rate of 100% in chicken lice, whereas a higher concentration of cloves, lemongrass, ginger, Makwan oil (0.416 µg/cm2), and Litsea oil (0.832 µg/cm2) was also found to be effective. A 100% rate of mortality for mites was observed using citronella and ginger oil at a concentration of 0.416 µg/cm2. At the same concentration, cloves, lemongrass, Litsea, and Makwan oil exhibited mortality rates in mites of 77.96%, 93.33%, 87.30%, and 93.49%, respectively. The efficacy of citronella oil and ginger oil against lice and mites was further examined in vivo. Citronella and ginger oil affected the rate of decline in lice from day 1 to day 14, whereas the number of mites living in nests declined from day 1 to day 7. The reduction of these parasitic insects may be correlated with the chemical constituents present in each essential oil. The active ingredients likely acted insecticidal agents against both parasitic insects. Moreover, the preparation developed here did not cause any side effects, such as dermatitis and respiratory disorders, during animal trials. Hence, preparations comprised of the essential oils of citronella and ginger can be further developed and used as insecticidal agents to control and/or eliminate chicken lice and mites on commercial farms.

Sign in / Sign up

Export Citation Format

Share Document