scholarly journals Modified Nanofibrous Filters with Durable Antibacterial Properties

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1255
Author(s):  
Ganna Ungur ◽  
Jakub Hrůza

The main aims of the research were to produce efficient nanofibrous filters with long-term antibacterial properties and to confirm the functionality of samples under real filtration conditions. A polyurethane solution was modified by micro- or nanoparticles of copper oxide in order to juxtapose the aggregation tendency of particles depending on their size. Modified solutions were electrospun by the Nanospider technique. The roller spinning electrode with a needle surface and static wire electrode were used for the production of functionalized nanofibers. The antibacterial properties of the modified nanofibrous layers were studied under simulated conditions of water and air filtration. Particular attention was paid to the fixation mechanism of modifiers in the structure of filters. It was determined that the rotating electrode with the needle surface is more efficient for the spinning of composite solutions due to the continuous mixing and the avoidance of particle precipitation at the bottom of the bath with modified polyurethane. Moreover, it was possible to state that microparticles of copper oxide are more appropriate antimicrobial additives due to their weaker aggregation tendency but stronger fixation in the fibrous structure than nanoparticles. From the results, it is possible to conclude that nanofibers with well-studied durable antibacterial properties may be recommended as excellent materials for water and air filtration applications.

Membranes ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 26
Author(s):  
Sara Metwally ◽  
Daniel P. Ura ◽  
Zuzanna J. Krysiak ◽  
Łukasz Kaniuk ◽  
Piotr K. Szewczyk ◽  
...  

Atopic dermatitis (AD) is a chronic, inflammatory skin condition, caused by wide genetic, environmental, or immunologic factors. AD is very common in children but can occur at any age. The lack of long-term treatments forces the development of new strategies for skin regeneration. Polycaprolactone (PCL) is a well-developed, tissue-compatible biomaterial showing also good mechanical properties. In our study, we designed the electrospun PCL patches with controlled architecture and topography for long-term release in time. Hemp oil shows anti-inflammatory and antibacterial properties, increasing also the skin moisture without clogging the pores. It can be used as an alternative cure for patients that do not respond to traditional treatments. In the study, we tested the mechanical properties of PCL fibers, and the hemp oil spreading together with the release in time measured on skin model and human skin. The PCL membranes are suitable material as patches or bandages, characterized by good mechanical properties and high permeability. Importantly, PCL patches showed release of hemp oil up to 55% within 6 h, increasing also the skin moisture up to 25%. Our results confirmed that electrospun PCL patches are great material as oil carriers indicating a high potential to be used as skin patches for AD skin treatment.


CrystEngComm ◽  
2015 ◽  
Vol 17 (2) ◽  
pp. 456-462 ◽  
Author(s):  
C. Tamames-Tabar ◽  
E. Imbuluzqueta ◽  
N. Guillou ◽  
C. Serre ◽  
S. R. Miller ◽  
...  

A novel biocompatible and bioactive zinc azelate metal–organic framework (BioMIL-5) was hydrothermally synthesized with interesting long-term antibacterial properties.


Author(s):  
Mohammed H. Sheikh ◽  
Muhammad A. R. Sharif

Phase change materials (PCM) are used in many energy storage applications. Energy is stored (latent heat of fusion) by melting the PCM and is released during resolidification. Dispersing highly conductive nanoparticles into the PCM enhances the effective thermal conductivity of the PCM, which in turn significantly improves the energy storage capability of the PCM. The resulting colloidal mixture with the nanoparticles in suspension is referred to as nanostructure enhanced phase change materials (NEPCM). A commonly used PCM for energy storage application is the family of paraffin (CnH2n+2). Mixing copper oxide (CuO) nanoparticles in the paraffin produces an effective and highly efficient NEPCM for energy storage. However, after long term application cycles, the efficiency of the NEPCM may deteriorate and it may need replacement with fresh supply. Disposal of the used NEPCM containing the nanoparticles is a matter of concern. Used NEPCM containing nanoparticles cannot be discarded directly into the environment because of various short term health hazards for humans and all living beings and unidentified long term environmental and health hazards due to nanoparticles. This problem will be considerable when widespread use of NEPCM will be practiced. It is thus important to develop technologies to separate the nanoparticles before the disposal of the NEPCM. The primary objective of this research work is to develop methods for the separation and reclamation of the nanoparticles from the NEPCM before its disposal. The goal is to find, design, test, and evaluate separation methods which are simple, safe, and economical. The specific NEPCM considered in this study is a colloidal mixture of dodecane (C12H26) and CuO nanoparticles (1–5% mass fraction and 5–15 nm size distribution). The nanoparticles are coated with a surfactant or stabilizing ligands for suspension stability in the mixture for a long period of time. Various methods for separating the nanoparticles from the NEPCM are explored. The identified methods include: (i) distillation under atmospheric and reduced pressure, (ii) mixing with alcohol mixture solvent, and (iii) high speed centrifugation. These different nanoparticle separation methods have been pursued and tested, and the results are analyzed and presented in this article.


2022 ◽  
Vol 13 ◽  
pp. 100176
Author(s):  
Richard Bright ◽  
Daniel Fernandes ◽  
Jonathan Wood ◽  
Dennis Palms ◽  
Anouck Burzava ◽  
...  

2020 ◽  
Vol 7 (5) ◽  
pp. 515-525
Author(s):  
Yuzhu He ◽  
Yahui Jin ◽  
Xiaoxia Ying ◽  
Qiong Wu ◽  
Shenglian Yao ◽  
...  

Abstract The repair of infective bone defects is a great challenge in clinical work. It is of vital importance to develop a kind of bone scaffold with good osteogenic properties and long-term antibacterial activity for local anti-infection and bone regeneration. A porous mineralized collagen (MC) scaffold containing poly(d,l-lactide-co-glycolic acid) (PLGA) microspheres loaded with two antibacterial synthetic peptides, Pac-525 or KSL-W was developed and characterized via scanning electron microscopy (SEM), porosity measurement, swelling and mechanical tests. The results showed that the MC scaffold embedded with smooth and compact PLGA microspheres had a positive effect on cell growth and also had antibacterial properties. Through toxicity analysis, cell morphology and proliferation analysis and alkaline phosphatase evaluation, the antibacterial scaffolds showed excellent biocompatibility and osteogenic activity. The antibacterial property evaluated with Staphylococcus aureus and Escherichia coli suggested that the sustained release of Pac-525 or KSL-W from the scaffolds could inhibit the bacterial growth aforementioned in the long term. Our results suggest that the antimicrobial peptides-loaded MC bone scaffold has good antibacterial and osteogenic activities, thus providing a great promise for the treatment of infective bone defects.


Polymers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1330 ◽  
Author(s):  
Laisa Cruzetta ◽  
Isadora M. Garcia ◽  
Gabriela de Souza Balbinot ◽  
Amanda S. Motta ◽  
Fabrício M. Collares ◽  
...  

The aim of the present study was to formulate dental adhesives with different concentrations of LiNbO3 and to evaluate their physicochemical and antibacterial properties. A dental adhesive was formulated using methacrylate monomers and photoinitiators and used as a control filler-free group. Subsequently, three experimental adhesives doped with LiNbO3 at different concentrations (1 wt.%, 2 wt.%, and 5 wt.%) were also formulated. All the experimental adhesives were assessed to evaluate the degree of conversion (DC), softening in solvent, immediate and long-term microtensile bond-strength (μ-TBS), radiopacity, ultimate tensile strength, and antibacterial activity. The incorporation of 1 wt.% of LiNbO3 had no negative effect on the DC of the adhesive resin compared to the control group (p > 0.05). We observed a decrease in the percentage of softening in solvent in the group LiNbO3 at 1 wt.% (p < 0.05). The addition of LiNbO3 increased the radiopacity at a concentration above 2 wt.%, and there was also an increase in cohesive strength (p < 0.05). The immediate μ-TBS increased for LiNbO3 at 5 wt.% (p < 0.05), and there was no statistical difference for the other groups compared to the control (p > 0.05). After six months, the group with 5 wt.% still presented the highest μ-TBS (p < 0.05). The adhesives showed no antimicrobial activity (p > 0.05). LiNbO3 was successfully incorporated in dental adhesives, increasing the radiopacity and their resistance to degradation. Although LiNbO3 offered no antibacterial properties, the reliability of LiNbO3 incorporation in the adhesive encourages new tests to better investigate the antimicrobial action of LiNbO3 through temperature variation.


2020 ◽  
Vol 8 (5) ◽  
pp. 1060-1070 ◽  
Author(s):  
Feng Zhang ◽  
Mingming Zhou ◽  
Weizhong Gu ◽  
Zheng Shen ◽  
Xiaohui Ma ◽  
...  

Dicalcium silicate (C2S) cements doped with Zn or Cu exhibited appreciable osteogenic activity and prolonged antibacterial potential in comparison with C2S cement.


Author(s):  
H. C. R Reuter ◽  
M. Owen ◽  
J. L. Goodenough

Paint-based protective films (PPFs) are used to protect condenser tubes from corrosion and erosion but have been shown to be susceptible to biofouling. Here, the biocidal properties of copper-oxide fillers incorporated into PPFs are explored in this paper. Specifically, two PPFs filled with 20% and 50% filler (by weight) are tested in parallel with a nonbiocidal ordinary epoxy PPF, and bare stainless steel tube. Using double-pipe co-current flow heat exchangers installed at a thermal power plant, actual cooling water exiting the condenser is evenly distributed between the test tubes. Heat transfer in the condenser is simulated by heated water flowing through each annulus of the double-pipe heat exchangers, thereby maintaining repeatable outer convection conditions. An exposure test of 125 days shows that the 50% biocide-filled PPF has the lowest fouling factor of all the tubes. The nonbiocidal epoxy has the highest fouling factor and the 20% filled PPF behaves similarly. Both of these are greater than the bare stainless steel control tube. The 50% filled PPF is compared to the fouling of an existing admiralty brass tube and the shapes of the fouling curves are similar. This evidence suggests that provided the filler concentration is sufficiently high, there is the potential for the copper-oxide filler to reduce the asymptotic composite fouling factor by virtue of its antibacterial properties.


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