scholarly journals Effects of Natural Reduced Water on Cognitive Function, Body Composition, and Psychological Function in Older Adults: Study Protocol for a Randomized Controlled Trial

2021 ◽  
Vol 4 (4) ◽  
pp. 73
Author(s):  
Takamitsu Shinada ◽  
Yuji Takano ◽  
Keisuke Kokubun ◽  
Hikari Iki ◽  
Yasuyuki Taki
Keyword(s):  
Body Composition ◽  
Cognitive Function ◽  
Animal Studies ◽  
Tap Water ◽  
Controlled Trial ◽  
Psychological Function ◽  
Water Group ◽  
Before And After ◽  
The Relationship ◽  
Reduced Water

Natural reduced water is natural water that contains active hydrogen and reduces oxidation. It is rare in the world, and in Japan, it is produced in the Hita area of Oita Prefecture (Hita Tenryosui water). Previous studies in humans have examined the effects of natural reduced water on diabetes, which is one of the known risks for dementia. Animal studies of natural reduced water have revealed anti-obesity and anti-anxiety effects. However, the effects of natural reduced water on cognitive function, body composition, and psychological function in humans are unknown. Therefore, we investigated the relationship between these items in elderly people who continuously consume natural reduced water. In this study, we recruited participants aged between 65 and 74 years. The participants were randomly and blindly assigned to a natural reduced water (Hita Tenryosui water) group or a control (tap water) group and drank 1 L of water daily for 6 months. Cognitive function, body composition, and psychological function were measured before and after the 6-month intervention period.

scholarly journals EFFECTS OF EXERCISE ON PHYSICAL FITNESS AND ANTHROPOMETRIC VARIABLES IN EX-CRACK COCAINE USERS

2017 ◽  
Vol 23 (4) ◽  
pp. 284-289
Author(s):  
Jéssica Abatti Martins ◽  
Ana Maria Volpato ◽  
Vanise dos Santos Ferreira Viero ◽  
Antonio Jose Grande ◽  
Leonardo Roever ◽  
...  
Keyword(s):  
Body Composition ◽  
Physical Fitness ◽  
Crack Cocaine ◽  
Controlled Trial ◽  
Exercise Group ◽  
Control Group ◽  
Beneficial Effects ◽  
Before And After ◽  
Cocaine Users ◽  
Total Body

ABSTRACT Introduction: Worldwide cocaine use in all its various forms is increasing; cocaine users exceeded 17 million in the world. In Brazil, this data is also alarming. A survey conducted in 2010 found that the country has more than 900,000 crack-cocaine users. Objective: To evaluate the effects of exercise on anthropometric variables and components of physical fitness in ex-crack cocaine users. Methods: Randomized controlled trial with 20 men, divided into exercise group (n=10) and control group (n=10), admitted to a detoxification center. We assessed the physical fitness components related to health (cardiorespiratory endurance, flexibility, muscular strength/endurance, and body composition) before and after the physical training program. Results: The exercise contributed to the maintenance of anthropometric variables, while the control group had an increased in total body fat and visceral fat. Regarding physical fitness, resistance training led to the increase of most variables studied, particularly strength and cardiorespiratory capacity. On the other hand, the VO2max and the strength of the sedentary subjects were reduced (P<0.05). Conclusion: The exercise showed beneficial effects on the components of physical fitness and maintenance of body composition.

scholarly journals The relationship between depression and cognitive function in adults with cardiovascular risk: Evidence from a randomised attention-controlled trial

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203343 ◽  
Author(s):  
Haley M. LaMonica ◽  
Daniel J. Biddle ◽  
Sharon L. Naismith ◽  
Ian B. Hickie ◽  
Paul Maruff ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Cognitive Function ◽  
Controlled Trial ◽  
The Relationship

scholarly journals Acute effects of coffee on neurocognitive function: an electroencephalography network analysis

2021 ◽  
Author(s):  
Hayom Kim ◽  
Sung Hoon Kang ◽  
Soon Ho Kim ◽  
Seong Hwan Kim ◽  
Jihyeon Hwang ◽  
...  
Keyword(s):  
Executive Function ◽  
Cognitive Function ◽  
Digit Span ◽  
Coffee Consumption ◽  
Beneficial Effects ◽  
Before And After ◽  
Trail Making ◽  
Network Properties ◽  
Improved Performance ◽  
The Relationship

Abstract The purpose of this study was to identify the mechanisms underlying effects of coffee on cognition in the context of brain networks. Here we investigated functional connectivity before and after drinking coffee using graph theoretical analysis of electroencephalography (EEG). Twenty-one healthy adults voluntarily participated in this study. The neuropsychological tests were consecutively performed at the start of the EEG recording and 30 min after coffee consumption. Graph analyses were performed and compared before and after coffee consumption. Correlation analyses were conducted to assess the relationship between changes in graph measures and those in cognitive function tests. FC was reorganized toward more efficient network properties after coffee consumption. Performance in Digit Span tests and Trail Making Test Part B improved after coffee consumption, and the improved performance in executive function was correlated with changes in graph measures, reflecting a shift toward efficient network properties. The beneficial effects of coffee on cognitive function might be attributed to the reorganization of FC toward more efficient network properties. Based on our findings, the patterns of network reorganization could be used as quantitative markers to elucidate the mechanisms underlying the beneficial effects of coffee on cognition, especially executive function.

Aerobic fitness and multidomain cognitive function in advanced age

2010 ◽  
Vol 23 (1) ◽  
pp. 114-124 ◽  
Author(s):  
Yael Netz ◽  
Tzvi Dwolatzky ◽  
Yael Zinker ◽  
Esther Argov ◽  
Ruth Agmon
Keyword(s):  
Cognitive Function ◽  
Physical Fitness ◽  
Controlled Trial ◽  
Cardiovascular Fitness ◽  
Advanced Age ◽  
Neuropsychological Battery ◽  
Cognitive Score ◽  
Cognitive Domains ◽  
And Function ◽  
The Relationship

ABSTRACTBackground: Studies generally describe the relationship between physical fitness and cognitive function by measuring only one or two specific cognitive tasks. In addition, in spite of the significant increase in life expectancy, the age of participants in these studies does not extend beyond a mean age of 70 years. This study was thus designed to examine the relationship between physical fitness and function in multiple cognitive domains in subjects older than those previously reported.Methods: Thirty-eight individuals, aged 65.3 to 85.3 years, performed a graded, progressive, maximal exercise test. Based on a median score of peak VO2, participants were divided into low-fitness and moderately-fit groups. Cognitive function was assessed by means of a computerized neuropsychological battery.Results: The moderately-fit group achieved significantly better scores on the global cognitive score (U = 97, p = 0.04), and a significant correlation was found between peak VO2 and attention, executive function, and global cognitive score (rs = .37, .39, .38 respectively). The trend for superior cognitive scores in the moderate-fitness compared to the low-fitness groups was unequivocal, both in terms of accuracy and reaction time.Conclusion: Maintenance of higher levels of cardiovascular fitness may help protect against cognitive deterioration, even at an advanced age. An adequately powered randomized controlled trial should be performed to further evaluate this hypothesis.

scholarly journals Feasibility of combining two individualized lung recruitment maneuvers at birth for very low gestational age infants: a retrospective cohort study

2020 ◽  
Author(s):  
Zalfa Kanaan ◽  
Coralie Bloch-Queyrat ◽  
Marouane Boubaya ◽  
Vincent Lévy ◽  
Pascal Bolot ◽  
...  
Keyword(s):  
Gestational Age ◽  
Animal Studies ◽  
Controlled Trial ◽  
Optimal Level ◽  
Progressive Increase ◽  
Lung Recruitment ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Recruitment Maneuvers ◽  
Before And After

Abstract BACKGROUND Lung recruitment at birth has been advocated as an effective method of improving the respiratory transition at birth. Sustained inflations (SI) and dynamic positive end-expiratory pressure (PEEP) were assessed in clinical and animal studies to define the optimal level. Our working hypothesis was that very low gestational age infants (VLGAI) < 32 weeks’ gestation require an individualized lung recruitment based on combining both manoeuvers. METHODS Between 2014 and 2016, 91 and 72 inborn VLGAI, requiring a respiratory support beyond a continuous positive airway pressure (CPAP) = 5 cmH2O, were enrolled before and after introducing these manoeuvers based on progressive increase in SI up to 15 seconds, with simultaneous gradual increase in PEEP up to 15 cmH2O, according to the cardiorespiratory response. Retrospective comparisons of the incidence of mechanical ventilation (MV) < 72h of life, short-term and before discharge morbidity were then performed. RESULTS Among extremely low gestational age infants (ELGAI) < 29 weeks’ gestation, the following outcomes decreased significantly: intubation (90% to 55%) and surfactant administration (54% to 12%) in the delivery room, MV (92% to 71%) and its mean duration < 72h of life (45h to 13h), administration of a 2nd dose of surfactant (35% to 12%) and postnatal corticosteroids (52% to 19%), and the rate of bronchopulmonary dysplasia (23 to 5%). Among VLGAI, all of these results were also significant. Neonatal mortality and morbidity were not different. CONCLUSIONS In our setting, combining two individualized lung recruitment maneuvers at birth was feasible and may be beneficial on short-term and before discharge pulmonary outcomes. A randomized controlled trial is needed to confirm these results.

scholarly journals Measurement of resting muscle oxygenation and the relationship with countermovement jumps and body composition in soccer players (Medición de la oxigenación muscular en reposo y la relación con los saltos)

2021 ◽  
Vol 16 (48) ◽  
Keyword(s):  
Body Composition ◽  
Team Sports ◽  
Arterial Occlusion ◽  
Muscle Oxygenation ◽  
Soccer Players ◽  
Individual Response ◽  
Countermovement Jump ◽  
Before And After ◽  
The Relationship ◽  
Resting Muscle

The measurement of resting muscle oxygenation capacity is under investigation in team sports. The aim of the current study was to observe the changes after a preseason, in muscle oxygen saturation (SmO2) at rest and the relationship with body composition and jump power in soccer players. 17 soccer players (age 21.8 ± 2.2 years) were enrolled. Body composition, somatotype, countermovement jump (CMJ) and single-leg countermovement jump (SLCMJ) were evaluated. Also, SmO2 at rest in the gastrocnemius muscle using the technique of arterial occlusion in the dominant leg and non-dominant leg was performed. All measurements were made before and after the preseason. The t-student test, Pearson’s correlation and inter-individual response of the subject’s statistic were applied to measure the magnitudes of change and the effect size. An inverse relationship was observed between SmO2 at the initial-occlusion (r= -0.82), final-occlusion (r= -0.79) and SmO2 recovery (r= -0.82) with the SLCMJ power. A moderate relationship was also observed between oxygen consumption and fat mass (r= 0.64). The measurement of SmO2 at rest can be considered as a possible performance parameter because it has determined its relationship with the ability to produce strength and jumping power in soccer players. === La medición de la capacidad de oxigenación del músculo en reposo está bajo investigación en los deportes de equipo. El objetivo del presente estudio fue observar los cambios, después de una pretemporada, en la saturación de oxígeno muscular (SmO2) en reposo y la relación con la composición corporal y la potencia de salto en los jugadores de fútbol. Participaron 17 jugadores de fútbol (edad 21.8 ± 2.2 años). Se evaluó la composición corporal, el somatotipo, el salto de contramovimiento (CMJ) y el salto de contramovimiento de una sola pierna (SLCMJ). Simultáneamente, se midió la SmO2 en reposo en el músculo gastrocnemio utilizando la técnica de oclusión arterial en la pierna dominante y no dominante. Todas las mediciones se realizaron antes y después de la pretemporada. Se aplico la prueba t-student, la correlación de Pearson y la estadística de respuesta inter-individual de los sujetos para medir las magnitudes de cambio y el tamaño del efecto. Se observó una relación inversa entre SmO2 en la oclusión inicial (r= -0.82), la oclusión final (r= -0.79) y la recuperación de SmO2 (r= -0.82) con la potencia SLCMJ. También se observó una relación moderada entre el consumo de oxígeno y la masa grasa (r=0.64). La medición de SmO2 en reposo se puede considerar como un posible parámetro de rendimiento, porque se identificó su relación con la capacidad de producir fuerza y potencia de salto en jugadores de fútbol.

scholarly journals Feasibility of combining two individualized lung recruitment maneuvers at birth for very low gestational age infants: a retrospective cohort study

2020 ◽  
Author(s):  
Zalfa Kanaan ◽  
Coralie Bloch-Queyrat ◽  
Marouane Boubaya ◽  
Vincent Lévy ◽  
Pascal Bolot ◽  
...  
Keyword(s):  
Gestational Age ◽  
Animal Studies ◽  
Controlled Trial ◽  
Optimal Level ◽  
Progressive Increase ◽  
Lung Recruitment ◽  
Short Term ◽  
Mortality And Morbidity ◽  
Recruitment Maneuvers ◽  
Before And After

Abstract BACKGROUND Lung recruitment at birth has been advocated as an effective method of improving the respiratory transition at birth. Sustained inflations (SI) and dynamic positive end-expiratory pressure (PEEP) were assessed in clinical and animal studies to define the optimal level. Our working hypothesis was that very low gestational age infants (VLGAI) < 32 weeks’ gestation require an individualized lung recruitment based on combining both manoeuvers. METHODS Between 2014 and 2016, 91 and 72 inborn VLGAI, requiring a respiratory support beyond a continuous positive airway pressure (CPAP) = 5 cmH2O, were enrolled before and after introducing these manoeuvers based on progressive increase in SI up to 15 seconds, with simultaneous gradual increase in PEEP up to 15 cmH2O, according to the cardiorespiratory response. Retrospective comparisons of the rate of mechanical ventilation (MV) < 72h of life, short-term and before discharge morbidity were then performed. RESULTS Among extremely low gestational age infants (ELGAI) < 29 weeks’ gestation, the following outcomes decreased significantly: intubation (90% to 55%) and surfactant administration (54% to 12%) in the delivery room, MV (92% to 71%) and its mean duration < 72h of life (45h to 13h), administration of a 2nd dose of surfactant (35% to 12%) and postnatal corticosteroids (52% to 19%), and the rate of bronchopulmonary dysplasia (23 to 5%). Among VLGAI, all of these results were also significant. Neonatal mortality and morbidity were not different. CONCLUSIONS In our setting, combining two individualized lung recruitment maneuvers at birth was feasible and may be beneficial on short-term and before discharge pulmonary outcomes. A randomized controlled trial is needed to confirm these results.

scholarly journals The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people

2007 ◽  
Vol 98 (5) ◽  
pp. 960-968 ◽  
Author(s):  
Simone J. P. M. Eussen ◽  
Per M. Ueland ◽  
Robert Clarke ◽  
Henk J. Blom ◽  
Willibrord H. L. Hoefnagels ◽  
...  
Keyword(s):  
Executive Function ◽  
Folic Acid ◽  
Cognitive Function ◽  
Controlled Trial ◽  
Memory Performance ◽  
Memory Function ◽  
Double Blind ◽  
Before And After ◽  
Combined Supplementation ◽  
The One

The importance of the one-carbon metabolites, choline and homocysteine, to brain function is well known. However, the associations between the one-carbon metabolites choline, betaine, methionine and dimethylglycine with cognition in elderly are unclear. We therefore examined the associations of these metabolites with cognition in a double-blind, placebo-controlled trial. Individuals (n 195) were randomized to receive daily oral capsules with either 1000 μg cobalamin (vitamin B12), or 1000 μg cobalamin plus 400 μg folic acid, or placebo for 24 weeks. Concentrations of homocysteine, methionine, choline, betaine and dimethylglycine were assessed before and after 12 and 24 weeks of treatment. Cognitive function, including domains of attention, construction, sensomotor speed, memory and executive function, was assessed before and after 24 weeks of treatment. At baseline, elevated plasma homocysteine was associated with lower performance of attention, construction, sensomotor speed and executive function. In addition, betaine was positively associated with better performance of construction, sensomotor speed and executive function, whereas elevated concentrations of methionine were positively associated with sensomotor speed. Daily combined supplementation with cobalamin plus folic acid decreased total homocysteine concentrations by 36 %, and increased betaine concentrations by 38 %. Participants with the largest increases in betaine concentrations showed a borderline significant (P = 0·07) higher memory performance compared to those without it. Although this trial observed associations of homocysteine and betaine with cognitive domains prior to supplementation, decreased concentrations of homocysteine were not related to improved cognitive performance. There was a tendency of participants with the largest increases in betaine concentrations to show the greatest improvement in memory function.

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