scholarly journals From Impure to Purified Silver Nanoparticles: Advances and Timeline in Separation Methods

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3407
Author(s):  
Catarina S. M. Martins ◽  
Helena B. A. Sousa ◽  
João A. V. Prior

AgNPs have exceptional characteristics that depend on their size and shape. Over the past years, there has been an exponential increase in applications of nanoparticles (NPs), especially the silver ones (AgNPs), in several areas, such as, for example, electronics; environmental, pharmaceutical, and toxicological applications; theragnostics; and medical treatments, among others. This growing use has led to a greater exposure of humans to AgNPs and a higher risk to human health and the environment. This risk becomes more aggravated when the AgNPs are used without purification or separation from the synthesis medium, in which the hazardous synthesis precursors remain unseparated from the NPs and constitute a severe risk for unnecessary environmental contamination. This review examines the situation of the available separation methods of AgNPs from crude suspensions or real samples. Different separation techniques are reviewed, and relevant data are discussed, with a focus on the sustainability and efficiency of AgNPs separation methods.

2021 ◽  
Vol 19 (3) ◽  
pp. 247-257
Author(s):  
Yuliya A. Morozova ◽  
Dmitry S. Dergachev ◽  
Mikhail A. Subotyalov

Over the past few decades, nanoparticles of metals, and in particular silver, with a diameter of less than 100 nm have significantly expanded their field of application for various biomedical purposes. So, silver nanoparticles have great potential in a wide range of applications as antimicrobial agents, coatings for biomedical products, carriers for drug delivery, bioengineering, since they have discrete physical properties and wide biochemical functionality. Studies have shown that the size, morphology, stability and properties (chemical and physical) of metal nanoparticles are strongly influenced by the conditions of the experiment, the kinetics of the interaction of metal ions with reducing agents and the adsorption processes of the stabilizer with metal nanoparticles. This review aims to analyze the use of silver nanoparticles in modern medicine based on data from domestic and foreign literature over the past five years. The study confirmed the high biological activity of drugs with nanoserebrum as anti-inflammatory, antimicrobial agents, antifungals, the presence of an inhibitory effect on protozoa, antioxidant and anticancer effects, and substantiated the relevance of use in bioengineering and dentistry. However, rapid advances and advances in technology have led to concerns about the potential risk associated with the use and application of silver nanoparticles to human health and the environment. Therefore, this review attempts to characterize and quantify the potential harmful effects of silver nanoparticles on the health of laboratory animals and humans, and focuses on ways to neutralize or reduce the toxic effects of silver nanoparticles on the human body.


2021 ◽  
pp. 002203452110018
Author(s):  
J.T. Wright ◽  
M.C. Herzberg

Our ability to unravel the mysteries of human health and disease have changed dramatically over the past 2 decades. Decoding health and disease has been facilitated by the recent availability of high-throughput genomics and multi-omics analyses and the companion tools of advanced informatics and computational science. Understanding of the human genome and its influence on phenotype continues to advance through genotyping large populations and using “light phenotyping” approaches in combination with smaller subsets of the population being evaluated using “deep phenotyping” approaches. Using our capability to integrate and jointly analyze genomic data with other multi-omic data, the knowledge of genotype-phenotype relationships and associated genetic pathways and functions is being advanced. Understanding genotype-phenotype relationships that discriminate human health from disease is speculated to facilitate predictive, precision health care and change modes of health care delivery. The American Association for Dental Research Fall Focused Symposium assembled experts to discuss how studies of genotype-phenotype relationships are illuminating the pathophysiology of craniofacial diseases and developmental biology. Although the breadth of the topic did not allow all areas of dental, oral, and craniofacial research to be addressed (e.g., cancer), the importance and power of integrating genomic, phenomic, and other -omic data are illustrated using a variety of examples. The 8 Fall Focused talks presented different methodological approaches for ascertaining study populations and evaluating population variance and phenotyping approaches. These advances are reviewed in this summary.


Materials ◽  
2018 ◽  
Vol 11 (6) ◽  
pp. 891 ◽  
Author(s):  
Hyun-Jin Kim ◽  
Jun-Goo Shin ◽  
Choon-Sang Park ◽  
Dae Kum ◽  
Bhum Shin ◽  
...  

Measurement ◽  
2021 ◽  
pp. 109489
Author(s):  
Shah Rizwan Ahmed ◽  
Humera Anwar ◽  
Syed Waseem Ahmed ◽  
Muhammed Raza Shah ◽  
Ayaz Ahmed ◽  
...  

Author(s):  
PA Ganichev

Introduction: Polymer products have become inexpensive, convenient and widely used in all spheres of everyday life recently. Microplastics are found in seawater, wastewater, fresh water, foodstuffs, and air. Over the past few years, the presence of microplastics in treated tap and bottled water has been reported, raising questions and concerns about their potential human health effects. Objective: To summarize and systematize the results of studying health effects of exposure to microplastics in potable water. Materials and methods: A literature review was done based on ten topical articles and reviews published in 2014–2021 out of 64 sources found in the PubMed and Scopus international databases and the Russian Science Citation Index (RSCI). Results and conclusions: Generalization and systematization of the published research data demonstrated the lack of strong evidence to draw conclusions about human health effects of microplastics. Information on toxicokinetics and toxicodynamics of ingested microplastic particles is absent just like the studies of the most common shapes and sizes of plastic particles and health risks from exposure to such particles in drinking water.


Author(s):  
Matthias Golz ◽  
Florin Boeck ◽  
Sebastian Ritz ◽  
Gerd Holbach

The efforts to discover the world’s oceans — even in extremely deep-sea environments — have grown more and more in the past years. In this context, unmanned underwater vehicles play a central role. Underwater systems that are not tethered need to provide an apparatus to ensure a safe return to the surface. Therefore, positive buoyancy is required and can be achieved by either losing weight or expanding volume. A conservative method is the dropping of ballast weight. However, nowadays this method is not appropriate due to the environmental impact. This paper presents a ballast system for an automated ascent of a deep-sea seabed station in up to 6000 m depth. The ballast system uses a DC motor driven modified hydraulic pump and a compressed air auxiliary system inside a pressure vessel. With regard to the environmental contamination in case of a leakage, only water is used as ballast fluid. The modification of an ordinary oil-hydraulic radial piston pump and the set-up of the ballast system is introduced. Results from sea trials in the Atlantic Ocean are presented to verify the functionality of the ballast system.


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