scholarly journals Association between Dietary Cholesterol and Their Food Sources and Risk for Hypercholesterolemia: The 2012–2016 Korea National Health and Nutrition Examination Survey

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 846 ◽  
Author(s):  
Dongjoo Cha ◽  
Yongsoon Park
Keyword(s):  
Low Density Lipoprotein ◽  
Dietary Cholesterol ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Food Sources ◽  
Direct Effects ◽  
Low Density Lipoprotein Cholesterol ◽  
Processed Meats ◽  
Health And Nutrition ◽  
Cholesterol Intake

It remains unclear whether cholesterol intake can increase serum cholesterol. Therefore, the present study aimed to investigate the hypothesis that the risk for hypercholesterolemia was not associated with intake of dietary cholesterol after adjusting for saturated fatty acid (SFA). Based on the data from the 2012–2016 KNHANES, dietary cholesterol was positively associated with the risk for abnormalities in total cholesterol (TC) (odds ratio (OR): 1.153, 95% confidence interval (CI): 0.995–1.337; p = 0.028) and low-density lipoprotein cholesterol (LDL-C) (OR: 1.186, 95% CI: 1.019–1.382; p = 0.018) levels before adjusting for SFA; after adjusting for SFA, no significant associations were found between these variables. The mediation analysis showed that dietary cholesterol had no direct effects on the serum levels of TC and LDL-C; in contrast, SFA had significant indirect effects on the association between dietary cholesterol and serum levels of TC and LDL-C. Furthermore, processed meats, but not eggs and other meats, were positively associated with the risk for abnormalities in both TC (OR: 1.220, 95% CI: 1.083–1.374; p = 0.001) and LDL-C (OR: 1.193, 95% CI: 1.052–1.354; p = 0.004) levels. The present study suggested that higher intake of processed meats with high SFA, but not dietary cholesterol was associated with higher risk for abnormalities in TC and LDL-C levels.

scholarly journals Threshold-Effect Association of Dietary Cholesterol Intake with Dyslipidemia in Chinese Adults: Results from the China Health and Nutrition Survey in 2015

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 2885 ◽  
Author(s):  
Qiumin Huang ◽  
Hongru Jiang ◽  
Bing Zhang ◽  
Huijun Wang ◽  
Xiaofang Jia ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Dietary Cholesterol ◽  
Density Lipoprotein ◽  
Threshold Effect ◽  
Chinese Adults ◽  
Nutrition Survey ◽  
Chinese Adult ◽  
Health And Nutrition ◽  
Intake Level ◽  
Cholesterol Intake

The association of dietary cholesterol intake with dyslipidemia and subtypes is controversial. This study aimed to examine the association of dietary cholesterol intake with dyslipidemia and subtypes in Chinese adults. Using data from the China Health and Nutrition Survey (CHNS) in 2015, the present study selected 4383 participants aged 18–59 years who were free of diabetes, apoplexy, and myocardial infarction disease. Information was obtained on dietary intake, anthropometric measurements, and blood laboratory measurements. Dietary cholesterol intake was calculated based on the data collected by consecutive 3 days 24 h recalls combined with the weighing of household seasonings and categorized by 11 levels: The first 10 levels in ranges of 50 mg/day and the 11th level at ≥500 mg/day. Dyslipidemia, hypercholesterolemia, hypertriglyceridemia, low-density lipoprotein (LDL)-hypercholesterolemia, and high-density lipoprotein (HDL)-hypocholesterolemia were defined based on the Chinese adult dyslipidemia prevention guide (2016 edition). Multivariable logistic regressions were performed to examine the association of dietary cholesterol intake levels with dyslipidemia and subtypes. The prevalence of dyslipidemia was 37.5% among Chinese adults in 2015 (hypercholesterolemia 9.6%, HDL-hypocholesterolemia 21.1%, LDL-hypercholesterolemia 12.7%, and hypertriglyceridemia 15.2%). The lowest prevalence of hypercholesterolemia and LDL-hypercholesterolemia was 6.7% and 9.4%, respectively, which was relative to a dietary cholesterol intake level of 100.0 to <150.0 mg/day. After adjusting for all potential confounders, adults with the highest dietary cholesterol intake level of ≥500 mg/day compared with the dietary cholesterol intake of 100.0 to <150.0 mg/day showed one-time higher odds of hypercholesterolemia (odds ratios (OR) 2.0, 95% confidence intervals (CI) 1.3–3.3), as well as LDL-hypercholesterolemia (OR 2.0, 95% CI 1.3–3.0), but a null association of dietary cholesterol intake with dyslipidemia, hypertriglyceridemia, and HDL-hypocholesterolemia. The study suggested that a dietary cholesterol intake level of 500 mg/day and above may be a threshold point for high odds of hypercholesterolemia and LDL-hypercholesterolemia.

Abstract 4996: Six-year Trends in Low-Density Lipoprotein Cholesterol Goal Achievement in High-Risk United States Residents: National Health and Nutrition Examination Survey, 1999 to 2004

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Kunal N Karmali ◽  
Matthew C Tattersall ◽  
Michael W Cullen ◽  
Jon G Keevil
Keyword(s):  
High Risk ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Goal Achievement ◽  
Low Density Lipoprotein Cholesterol ◽  
Health And Nutrition ◽  
Chd Risk ◽  
Cholesterol Goal ◽  
Equivalent Conditions ◽  
Risk Equivalent

Background : In 2001, the Adult Treatment Panel III guidelines expanded the definition of high risk by including coronary heart disease (CHD) risk equivalent conditions. Low-density lipoprotein cholesterol (LDL-C) goals for all high-risk patients were intensified to < 100 mg/dL. This study investigates the size of the high-risk U.S. population with and without CHD and the percent LDL-C goal achievement across six years. Methods : Data from three National Health and Nutrition Examination Surveys: 1999–2000, 2001–2002, and 2003–2004 were analyzed to identify U.S. residents at high risk per ATP III guidelines. The size of each survey’s high-risk cohort and percentage LDL-C goal achievement was stratified by presence of CHD or CHD risk equivalent conditions. Results : Across the three surveys, the high-risk population was 22.2, 23.8 and 28.0 million. The percentage of all high-risk individuals with LDL-C < 100 mg/dL was 22.9%, 31.5% and 32.9%. Goal achievement in those without CHD was 20.2%, 26.0% and 31.5%. In CHD patients, goal achievement increased from 27.0% (1999–2000) to 40.9% (2001–2002) but then dropped to 35.1% (2003–2004). Conclusions : Across six years from 1999 to 2004, U.S. residents at high risk increased by 26.2% (5.8 million) compared to a 5.2% (8.3 million) rise in eligible population. Improvement in LDL-C goal achievement for those without CHD was consistent across the three surveys. Those with CHD also had a robust improvement from 1999–2000 to 2001–2002. However, while a greater absolute number of those with CHD met goal in 2003–2004, the percentage was reduced. This suggests a need for renewed attention to LDL-C goal achievement in individuals with CHD. High Risk Cholesterol Goal Achievement by CHD status

scholarly journals Comparación de lípidos sanguíneos entre pollos de engorde y gallinas ponedoras

2018 ◽  
Vol 65 (1) ◽  
Author(s):  
J. H. Osorio ◽  
J. D. Flores
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
High Density Lipoprotein Cholesterol ◽  
Laying Hens ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol

Objective: To compare serum levels of total cholesterol, triglycerides, low density lipoprotein cholesterol and high density lipoprotein cholesterol between broilers and laying hens. Materials and Methods: the present is a cross study, descriptive and analytic. Data was analyzed using simple ANOVA, the program Statgraphics Plus 5.1 was used. The study was performed at Universidad de Caldas in Manizales (Colombia). After fasting, blood from 30 broilers (Cobb 500 line) of 35-day-old and 40 laying hens (Hy-Line W-36 line) of 26-weeks-old. Serum levels of triglycerides, total cholesterol, low density lipoprotein cholesterol and high density lipoprotein cholesterol was measured by enzymatic colorimetric methods, direct method (detergent + N,Nbis (4-sulfobutyl)-m-toluidine) was used for the lipoprotein cholesterol. Results: Between broilers (Cobb 500 line) and (laying hens (Hy-line W-36 line) was significant difference in serum levels of triglycerides and in serum levels of high density lipoprotein cholesterol (P <0.05); serum levels of total cholesterol and serum levels of low density lipoprotein cholesterol, no differences were found (P> 0.05) Conclusions: Despite differences in gender, age, and production system among broilers Cobb 500 line and laying hens Hy-Line W-36, no differences were found between serum total cholesterol and low density lipoprotein cholesterol.

scholarly journals Effect of Hyper and Hypothyroidism on Lipid Profile and Liver Function of Male Rats

2011 ◽  
Vol 8 (4) ◽  
pp. 926-933
Author(s):  
Baghdad Science Journal
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Physiological Saline ◽  
Serum Levels ◽  
Lipoprotein Cholesterol ◽  
Male Rats ◽  
Control Group ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Significant Difference

This study was designed to investigate the effect of thyroid hormone disturbance on lipids profiles and liver functions. Eighteen mature male rats Rattus norvegicus were divided into three groups. The first and the second groups were injected subcutaneously with thyroxine (T4) and carbimazol (both at 600 µg/kg BW) respectively on alternate days, to produce recurrent periods of hyper and hypothyroidism .The control group which is the third group was injected with physiological saline. The process continued 4 weeks, after that, injection, blood specimens were collected to estimate serum levels of T3 and T4, Total cholesterol (TC), Triglycerides (TG), High density lipoprotein cholesterol (HDL-C), Low density lipoprotein cholesterol (LDL-C) and Very low density lipoprotein cholesterol (VLDL-C) were determined in the serum. In addition to that, we measure GOT, GPT and CPK enzymes activity. The results showed no significant difference in body weight and a significant increase (P

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