scholarly journals Negative Energy Balance Induced by Exercise or Diet: Effects on Visceral Adipose Tissue and Liver Fat

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 891 ◽  
Author(s):  
Robert Ross ◽  
Simrat Soni ◽  
Sarah Houle
Keyword(s):  
Adipose Tissue ◽  
Energy Balance ◽  
Health Risk ◽  
Visceral Adipose Tissue ◽  
Cardiometabolic Risk ◽  
Negative Energy ◽  
Negative Energy Balance ◽  
Liver Fat ◽  
Effective Strategies ◽  
Visceral Adipose

The indisputable association between visceral adipose tissue (VAT) and cardiometabolic risk makes it a primary target for lifestyle-based strategies designed to prevent or manage health risk. Substantive evidence also confirms that liver fat (LF) is positively associated with increased health risk and that reduction is associated with an improved metabolic profile. The independent associations between reductions in VAT, LF, and cardiometabolic risk is less clear. In this narrative review, we summarize the evidence indicating whether a negative energy balance induced by either an increase in energy expenditure (aerobic exercise) or a decrease in energy intake (hypocaloric diet) are effective strategies for reducing both VAT and LF. Consideration will be given to whether a dose-response relationship exists between the negative energy balance induced by exercise or diet and reduction in either VAT or LF. We conclude with recommendations that will help fill gaps in knowledge with respect to lifestyle-based strategies designed to reduce VAT and LF.

scholarly journals Adherence to a plant-based diet in relation to adipose tissue volumes and liver fat content

2020 ◽  
Vol 112 (2) ◽  
pp. 354-363
Author(s):  
Ilka Ratjen ◽  
Jakub Morze ◽  
Janna Enderle ◽  
Marcus Both ◽  
Jan Borggrefe ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Fat Distribution ◽  
Abdominal Fat ◽  
Fat Content ◽  
Liver Fat ◽  
Healthy Plant ◽  
Liver Fat Content ◽  
Subcutaneous Abdominal Adipose Tissue ◽  
Visceral Adipose

ABSTRACT Background Better adherence to plant-based diets has been linked to lower risk of metabolic diseases but the effect on abdominal fat distribution and liver fat content is unclear. Objectives We aimed to examine the association between different plant-based diet indices and measures of abdominal fat distribution and liver fat content. Methods In a population-based sample of 578 individuals from Northern Germany (57% male, median age 62 y), diet was assessed with a validated FFQ and an overall, a healthy, and an unhealthy plant-based diet index were derived. Participants underwent MRI to assess volumes of visceral and subcutaneous abdominal adipose tissue and liver signal intensity (LSI), a measure of liver fat content. Fatty liver disease (FLD) was defined as log LSI ≥3.0. Cross-sectional associations of the plant-based diet indices with visceral and subcutaneous abdominal fat volumes, LSI, and FLD were assessed in linear and logistic regression analyses. The most comprehensive model adjusted for age, sex, education, smoking, alcohol, physical activity, energy intake, diabetes, hyperlipidemia, and BMI. Results Higher overall and healthy plant-based diet indices both revealed statistically significant associations with lower visceral and subcutaneous abdominal adipose tissue volumes and with lower odds of FLD in multivariable-adjusted models without BMI. Upon additional adjustment for BMI, only the association of the healthy plant-based diet with visceral adipose tissue remained statistically significant (per 10-point higher healthy plant-based diet index, percentage change in visceral adipose tissue: −4.9%, 95% CI: −8.6%, −2.0%). None of the plant-based diet indices was associated with LSI. The unhealthy plant-based diet index was unrelated to any of the abdominal or liver fat parameters. Conclusions Adherence to healthy plant-based diets was associated with lower visceral adipose tissue. None of the other examined associations remained statistically significant after adjustment for BMI.

scholarly journals Adipose tissue remodeling in late-lactation dairy cows during feed-restriction-induced negative energy balance

2016 ◽  
Vol 99 (12) ◽  
pp. 10009-10021 ◽  
Author(s):  
G. Andres Contreras ◽  
Kyan Thelen ◽  
Sarah E. Schmidt ◽  
Clarissa Strieder-Barboza ◽  
Courtney L. Preseault ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Energy Balance ◽  
Dairy Cows ◽  
Tissue Remodeling ◽  
Negative Energy ◽  
Negative Energy Balance ◽  
Feed Restriction ◽  
Adipose Tissue Remodeling

1154 Feed restriction-induced negative energy balance alters the fatty acid profiles of adipose tissue and milk fat of dairy cows

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 553-554
Author(s):  
S. E. Schmidt ◽  
K. M. Thelen ◽  
C. L. Preseault ◽  
G. A. Contreras ◽  
A. L. Lock
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid ◽  
Energy Balance ◽  
Dairy Cows ◽  
Milk Fat ◽  
Negative Energy ◽  
Negative Energy Balance ◽  
Feed Restriction ◽  
Fatty Acid Profiles

scholarly journals Abdominal visceral adipose tissue ultrasound assessmet as a tool in predicting of high cardiometric risk obesity

2018 ◽  
Vol 15 (4) ◽  
pp. 70-75 ◽  
Author(s):  
M A Druzhilov ◽  
O Yu Druzhilova ◽  
T Yu Kuznetsova
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Cardiometabolic Risk ◽  
Clinical Signs ◽  
Cardiovascular Disorders ◽  
Metabolic Risk ◽  
Cardiovascular Remodeling ◽  
Visceral Adipose ◽  
Score Risk

Objective: to conduct the analysis of association abdominal visceral adipose tissue ultrasound indices with parameters of cardiovascular remodeling and metabolic risk factors with subsequent evaluation of their use as a predictor of high cardiometabolic risk obesity. Material and methods. Totally, 274 normotensive males investigated (mean age 44.8±5.0 y. o.), with no clinical signs of cardiovascular disorders and type 2 diabetes, with the SCORE risk

scholarly journals Profiling the Discordant Visceral Adipose Tissue–Ectopic Liver Fat Phenotype: Results from the Dallas Heart Study

2020 ◽  
Keyword(s):  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Fat Deposition ◽  
Liver Fat ◽  
Heart Study ◽  
Dallas Heart Study ◽  
Ectopic Liver ◽  
Visceral Adipose ◽  
Cardiometabolic Profile

The accumulation of visceral adipose tissue (VAT) and ectopic liver fat (ELF) generally parallel each other, but a proportion of individuals have discordant fat deposition. The cardiometabolic profile of individuals with a discordant phenotype is unknown.

scholarly journals Visceral adipose tissue measured by DXA correlates with measurement by CT and is associated with cardiometabolic risk factors in children

2014 ◽  
Vol 10 (3) ◽  
pp. 172-179 ◽  
Author(s):  
T. A. Bosch ◽  
D. R. Dengel ◽  
A. S. Kelly ◽  
A. R. Sinaiko ◽  
A. Moran ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Visceral Adipose

scholarly journals Visceral Adipose Tissue Indicates the Severity of Cardiometabolic Risk in Patients with and without Type 2 Diabetes: Results from the INSPIRE ME IAA Study

2012 ◽  
Vol 97 (5) ◽  
pp. 1517-1525 ◽  
Author(s):  
Jessica D. Smith ◽  
Anne-Laure Borel ◽  
Julie-Anne Nazare ◽  
Steven M. Haffner ◽  
Beverley Balkau ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Cardiometabolic Risk ◽  
Visceral Adipose

scholarly journals Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans

2020 ◽  
Vol 8 (2) ◽  
pp. e001860
Author(s):  
Maria Apostolopoulou ◽  
Ruth Gordillo ◽  
Sofiya Gancheva ◽  
Klaus Strassburger ◽  
Christian Herder ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Fatty Liver Disease ◽  
Liver Fat ◽  
Liver Fat Content ◽  
Alcoholic Fatty Liver ◽  
Visceral Adipose ◽  
Alcoholic Fatty Liver Disease

IntroductionSphingolipid accumulation has been linked to obesity, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). A recent study showed that depletion of dihydroceramide desaturase-1 (DES-1) in adipose and/or liver tissue decreases ceramide-to-dihydroceramide ratios (ceramide/dihydroceramide) in several tissues and improves the metabolic profile in mice. We tested the hypothesis that ceramide/dihydroceramide would also be elevated and relate positively to liver fat content and insulin resistance in humans.Research design and methodsThus, we assessed total and specific ceramide/dihydroceramide in various biosamples of 7 lean and 21 obese volunteers without or with different NAFLD stages, who were eligible for abdominal or bariatric surgery, respectively. Biosamples were obtained from serum, liver, rectus abdominis muscle as well as subcutaneous abdominal and visceral adipose tissue during surgery.ResultsSurprisingly, certain serum and liver ceramide/dihydroceramide ratios were reduced in both obesity and non-alcoholic steatohepatitis (NASH) and related inversely to liver fat content. Specifically, hepatic ceramide/dihydroceramide (species 16:0) related negatively to hepatic mitochondrial capacity and lipid peroxidation. In visceral adipose tissue, ceramide/dihydroceramide (species 16:0) associated positively with markers of inflammation.ConclusionThese results failed to confirm the relationships of ceramide/dihydroceramide in humans with different degree of insulin resistance. However, the low hepatic ceramide/dihydroceramide favor a role for dihydroceramide accumulation in NASH, while a specific ceramide/dihydroceramide ratio in visceral adipose tissue suggests a role of ceramides in obesity-associated low-grade inflammation.

Independent associations between liver fat, visceral adipose tissue, and metabolic risk factors in men

2007 ◽  
Vol 32 (2) ◽  
pp. 265-272 ◽  
Author(s):  
Kathleen P. McMillan ◽  
Jennifer L. Kuk ◽  
Timothy S. Church ◽  
Steven N. Blair ◽  
Robert Ross
Keyword(s):  
Risk Factors ◽  
Adipose Tissue ◽  
Visceral Adipose Tissue ◽  
Metabolic Profile ◽  
Univariate Analysis ◽  
Density Lipoprotein ◽  
Metabolic Risk Factors ◽  
Liver Fat ◽  
Metabolic Risk ◽  
Visceral Adipose

The independent associations between liver fat, visceral adipose tissue (AT), and metabolic risk factors are unclear. Although it has been reported that visceral AT is the strongest predictor of metabolic risk, liver fat has also been reported as a strong independent associate of a deleterious metabolic profile. We examined the independent associations between liver fat, visceral AT, and metabolic risk factors in a sample of 293 men varying widely in adiposity. Liver fat and abdominal AT were measured by computed tomography (CT). Univariate analysis revealed that liver fat was associated (p < 0.05) with triglycerides (TG), systolic blood pressure (SBP), and total cholesterol (TC), but not with glucose or high-density lipoprotein cholesterol (HDLC). Liver fat remained a significant correlate (p < 0.05) of TG and TC after control for age and subcutaneous AT or cardiorespiratory fitness (CRF), but not after adjustment for visceral AT alone. Conversely, visceral AT remained significantly associated with TG, SBP, glucose, HDLC (p < 0.01), and TC (p = 0.05) independent of liver fat, subcutaneous AT, CRF, and age. Both liver fat and visceral AT were associated with metabolic risk in men. However, when controlled for each other, visceral AT was the only independent associate of metabolic risk.

Sign in / Sign up

Export Citation Format

Share Document