Polish Translation and Validation of the Mini Sarcopenia Risk Assessment (MSRA) Questionnaire to Assess Nutritional and Non-Nutritional Risk Factors of Sarcopenia in Older Adults

A simple, short, cheap, and reasonably sensitive and specific screening tool assessing both nutritional and non-nutritional risk factors for sarcopenia is needed. Potentially, such a tool may be the Mini Sarcopenia Risk Assessment (MSRA) Questionnaire, which is available in a seven-item (MSRA-7) and five-item (MSRA-5) version. The study’s aim was Polish translation and validation of both MSRA versions in 160 volunteers aged ≥60 years. MSRA was validated against the six sets of international diagnostic criteria for sarcopenia used as the reference standards. PL-MSRA-7 and PL-MSRA-5 both had high sensitivity (≥84.9%), regardless of the reference standard. The PL-MSRA-5 had better specificity (44.7–47.2%) than the PL-MSRA-7 (33.1–34.7%). Both questionnaires had similarly low positive predictive value (PL-MSRA-5: 17.9–29.5%; PL-MSRA-7: 14.4–25.2%). The negative predictive value was generally high for both questionnaires (PL-MSRA-7: 89.8–95.9%; PL-MSRA-5: 92.3–98.5%). PL-MSRA-5 had higher accuracy than the PL-MSRA-7 (50.0–55% vs. 39.4–45%, respectively). Based on the results, the Mini Sarcopenia Risk Assessment questionnaire was successfully adopted to the Polish language and validated in community-dwelling older adults from Poland. When compared with PL-MSRA-7, PL-MSRA-5 is a better tool for sarcopenia risk assessment.

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Accuracy of clinical-functional tools to identify risk of falls among community-dwelling older adults

Fisioterapia em Movimento ◽

10.1590/1980-5918.032.ao02 ◽

2019 ◽

Vol 32 ◽

Author(s):

Raphaela Xavier Sampaio ◽

Amanda Maria Santos Abreu ◽

Cristiane Almeida Nagata ◽

Patrícia Azevedo Garcia

Keyword(s):

Older Adults ◽

Risk Assessment ◽

Predictive Value ◽

Fall Risk ◽

Community Dwelling ◽

Methodological Study ◽

Risk Of Falls ◽

One Year ◽

Sensitivity Specificity ◽

Community Dwelling Older Adults

Abstract Introduction: The identification of older adults who present greater chances of falling is the first step in the prevention of falls. Clinical instruments have been shown to be able to differentiate fallers from non-fallers, but their predictive validity remains controversial. Objective: To investigate the accuracy of the Short Physical Performance Battery (SPPB) and Quick Screen Clinical Fall Risk Assessment (QuickScreen) instruments to identify risk of falls in community-dwelling older adults. Method: This is a prospective methodological study with 81 older adults (≥ 60 years), assessed at baseline by SPPB and QuickScreen and monitored after one year to identify the occurrence of falls. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and area under the ROC curve (AUC) were calculated. Results: 28.4% of the sample reported falls. QuickScreen presented 52.2% sensitivity, 74.1% specificity, 44.4% PPV, 79.6% NPV and 0.656 AUC. The AUC for SPPB was not significant (p = 0.087). Conclusion: QuickScreen presented poor accuracy when predicting falls and SPPB was unable to identify community-dwelling older adults at risk of falls. The QuickScreen instrument stood out for its high potential to identify true negatives.

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Cross-Country Differences and Similarities in Undernutrition Prevalence and Risk as Measured by SCREEN II in Community-Dwelling Older Adults

Healthcare ◽

10.3390/healthcare8020151 ◽

2020 ◽

Vol 8 (2) ◽

pp. 151

Author(s):

Jos W. Borkent ◽

Heather Keller ◽

Carol Wham ◽

Fleur Wijers ◽

Marian A. E. de van der Schueren

Keyword(s):

Risk Factors ◽

Older Adults ◽

Community Dwelling ◽

Nutritional Risk ◽

Sensitivity Analyses ◽

Data Sampling ◽

Prevalence Rates ◽

Nutrition Risk ◽

Screen Ii ◽

Community Dwelling Older Adults

Undernutrition is highly prevalent among community-dwelling older adults. Early identification of nutrition risk is important to prevent or treat undernutrition. This study describes the prevalence rates of nutrition risk in community-dwelling older adults (aged ≥ 65) using the same validated tool across different countries and aims to identify differences in nutritional risk factors. Cross-sectional data was obtained from three datasets including participants from the Netherlands (NL), Canada (CA) and New Zealand (NZ). Seniors in the Community Risk Evaluation for Eating and Nutrition II (SCREEN II) was used to assess nutritional risk factors and prevalence of risk. Differences between countries were tested with logistic and linear regression. Sensitivity analyses were conducted to test the influence of sampling strategy. A total of 13,340 participants were included, and 66.3% were found to be at high nutrition risk. After stratifying the data for method of data sampling, prevalence rates showed some differences across countries (NL: 61.5%, NZ: 68.2%, CA: 70.1%). Risk factor items that contributed to nutrition risk also differed among countries: NZ and CA participants scored higher for weight change, skipping meals, problems with meal preparation, use of meal replacements, problems with biting and chewing, low fluid intake and problems with doing groceries, as compared to participants in NL. Low intake of fruits and vegetables and meat were more prevalent in NL. In conclusion: nutrition risk is a worldwide, highly prevalent problem among community-dwelling older adults, but risk factors contributing to nutrition risk differ by country.

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Corrigendum to “Oral Frailty Index-8 in the risk assessment of new-onset oral frailty and functional disability among community-dwelling older adults” Archives of Gerontology and Geriatrics, Volume 94 (2021) 104340

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2021.104466 ◽

2021 ◽

Vol 96 ◽

pp. 104466

Author(s):

Tomoki Tanaka ◽

Hirohiko Hirano ◽

Yuki Ohara ◽

Misa Nishimoto ◽

Katsuya Iijima

Keyword(s):

Older Adults ◽

Risk Assessment ◽

Functional Disability ◽

Frailty Index ◽

Community Dwelling ◽

Community Dwelling Older Adults ◽

Oral Frailty ◽

New Onset

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Oral Frailty Index-8 in the risk assessment of new-onset oral frailty and functional disability among community-dwelling older adults

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2021.104340 ◽

2021 ◽

Vol 94 ◽

pp. 104340

Author(s):

Tomoki Tanaka ◽

Hirohiko Hirano ◽

Yuki Ohara ◽

Misa Nishimoto ◽

Katsuya Iijima

Keyword(s):

Older Adults ◽

Risk Assessment ◽

Functional Disability ◽

Frailty Index ◽

Community Dwelling ◽

Community Dwelling Older Adults ◽

Oral Frailty ◽

New Onset

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Diagnostic Power of Circulatory Metabolic Biomarkers as Metabolic Syndrome Risk Predictors in Community-Dwelling Older Adults in Northwest of England (A Feasibility Study)

Nutrients ◽

10.3390/nu13072275 ◽

2021 ◽

Vol 13 (7) ◽

pp. 2275

Author(s):

Razieh Hassannejad ◽

Hamsa Sharrouf ◽

Fahimeh Haghighatdoost ◽

Ben Kirk ◽

Farzad Amirabdollahian

Keyword(s):

Risk Factors ◽

Older Adults ◽

Metabolic Syndrome ◽

Roc Analysis ◽

Cross Validation ◽

Community Dwelling ◽

Tnf Α ◽

Diagnostic Power ◽

Metabolic Biomarkers ◽

Community Dwelling Older Adults

Background: Metabolic Syndrome (MetS) is a cluster of risk factors for diabetes and cardiovascular diseases with pathophysiology strongly linked to aging. A range of circulatory metabolic biomarkers such as inflammatory adipokines have been associated with MetS; however, the diagnostic power of these markers as MetS risk correlates in elderly has yet to be elucidated. This cross-sectional study investigated the diagnostic power of circulatory metabolic biomarkers as MetS risk correlates in older adults. Methods: Hundred community dwelling older adults (mean age: 68.7 years) were recruited in a study, where their blood pressure, body composition and Pulse Wave Velocity (PWV) were measured; and their fasting capillary and venous blood were collected. The components of the MetS; and the serum concentrations of Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α), Plasminogen Activator Inhibitor-I (PAI-I), Leptin, Adiponectin, Resistin, Cystatin-C, C-Reactive Protein (CRP), insulin and ferritin were measured within the laboratory, and the HOMA1-IR and Atherogenic Index of Plasma (AIP) were calculated. Results: Apart from other markers which were related with some cardiometabolic (CM) risk, after Bonferroni correction insulin had significant association with all components of Mets and AIP. These associations also remained significant in multivariate regression. The multivariate odds ratio (OR with 95% confidence interval (CI)) showed a statistically significant association between IL-6 (OR: 1.32 (1.06–1.64)), TNF-α (OR: 1.37 (1.02–1.84)), Resistin (OR: 1.27 (1.04–1.54)) and CRP (OR: 1.29 (1.09–1.54)) with MetS risk; however, these associations were not found when the model was adjusted for age, dietary intake and adiposity. In unadjusted models, insulin was consistently statistically associated with at least two CM risk factors (OR: 1.33 (1.16–1.53)) and MetS risk (OR: 1.24 (1.12–1.37)) and in adjusted models it was found to be associated with at least two CM risk factors and MetS risk (OR: 1.87 (1.24–2.83) and OR: 1.25 (1.09–1.43)) respectively. Area under curve (AUC) for receiver operating characteristics (ROC) demonstrated a good discriminatory diagnostics power of insulin with AUC: 0.775 (0.683–0.866) and 0.785 by cross validation and bootstrapping samples for at least two CM risk factors and AUC: 0.773 (0.653–0.893) and 0.783 by cross validation and bootstrapping samples for MetS risk. This was superior to all other AUC reported from the ROC analysis of other biomarkers. Area under precision-recall curve for insulin was also superior to all other markers (0.839 and 0.586 for at least two CM risk factors and MetS, respectively). Conclusion: Fasting serum insulin concentration was statistically linked with MetS and its risk, and this link is stronger than all other biomarkers. Our ROC analysis confirmed the discriminatory diagnostic power of insulin as CM and MetS risk correlate in older adults.

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Risk Factors for Mobility Limitation in Community-Dwelling Older Adults: A Social Ecological Perspective

Geriatric Nursing ◽

10.1016/j.gerinurse.2007.07.002 ◽

2008 ◽

Vol 29 (2) ◽

pp. 133-140 ◽

Cited By ~ 72

Author(s):

Hye A. Yeom ◽

Julie Fleury ◽

Colleen Keller

Keyword(s):

Risk Factors ◽

Older Adults ◽

Community Dwelling ◽

Mobility Limitation ◽

Ecological Perspective ◽

Social Ecological ◽

Community Dwelling Older Adults

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10-Year Renal Function Trajectories in Community-Dwelling Older Adults: Exploring the Risk Factors for Different Patterns

Journal of Clinical Medicine ◽

10.3390/jcm7100373 ◽

2018 ◽

Vol 7 (10) ◽

pp. 373

Author(s):

Chia-Ter Chao ◽

Yung-Ming Chen ◽

Fu-Hui Ho ◽

Kun-Pei Lin ◽

Jen-Hau Chen ◽

...

Keyword(s):

Risk Factors ◽

Older Adults ◽

Logistic Regression ◽

Renal Function ◽

Estimated Glomerular Filtration Rate ◽

Community Dwelling ◽

Multivariate Logistic Regression ◽

Improve Risk Stratification ◽

Leukocyte Counts ◽

Community Dwelling Older Adults

Longitudinal changes of renal function help inform patients’ clinical courses and improve risk stratification. Rare studies address risk factors predicting changes in estimated glomerular filtration rate (eGFR) over time in older adults, particularly of Chinese ethnicity. We identified prospectively enrolled community-dwelling older adults (≥65 years) receiving annual health examinations between 2005 and 2015 with serum creatinine available continuously in a single institute, and used linear regression to derive individual’s annual eGFR changes, followed by multivariate logistic regression analyses to identify features associated with different eGFR change patterns. Among 500 elderly (71.3 ± 4.2 years), their mean annual eGFR changes were 0.84 ± 1.67 mL/min/1.73 m2/year, with 136 (27.2%) and 238 (47.6%) classified as having downward (annual eGFR change <0 mL/min/1.73 m2/year) and upward eGFR (≥1 mL/min/1.73 m2/year) trajectories, respectively. Multivariate logistic regression showed that higher age (odds ratio (OR) 1.08), worse renal function (OR 13.2), and more severe proteinuria (OR 9.86) or hematuria (OR 3.39) were predictive of a declining eGFR while greater waist circumference (OR 1.06) and higher leukocyte counts (OR 1.21) were predictive of an uprising 10-year eGFR. These findings elucidate important features associated with geriatric renal function variations, which are expected to improve their renal care.

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Prevalence and Multidimensional Risk Factors of Physical Frailty in Korean Community-Dwelling Older Adults: Findings from Korean Frailty and Aging Cohort Study

10.20944/preprints202009.0423.v1 ◽

2020 ◽

Author(s):

Heeeun Jung ◽

Miji Kim ◽

Yunhwan Lee ◽

Chang Won Won

Keyword(s):

Risk Factors ◽

Older Adults ◽

Cohort Study ◽

Medical Condition ◽

Glycosylated Hemoglobin ◽

Community Dwelling ◽

National Standard ◽

Timed Up And Go ◽

Frailty Phenotype ◽

Community Dwelling Older Adults

Frailty is defined as a state of increased vulnerability to stressors, and it predicts the disability and mortality in the older population. This study aimed to investigate standardized prevalence and multidimensional risk factors associated with frailty among the Korean community-dwelling older adults. We analyzed the baseline data of 2,907 adults aged 70–84 years (mean age 75.8±3.9 years, 57.8% women) in the Korean Frailty and Aging Cohort Study. The Fried frailty phenotype was used to define frailty. Analyzed data included sociodemographic, physical, physical function, biological, lifestyle, health condition, medical condition, psychological, and social domains. Data were standardized using the national standard population composition ratio based on the Korean Population and Housing Census. The standardized prevalence of frailty and pre-frailty was 7.9% (95% confidence interval [CI] 6.8–8.9%) and 57.2% (95% CI 45.1–48.8%), respectively. The following 14 risk factors had a significant association with frailty: at risk of malnutrition, sarcopenia, severe mobility limitation, poor social capital, rural dwellers, depressive, poor self-perceived health, polypharmacy, elevated high-sensitivity C-reactive protein, elevated glycosylated hemoglobin, low 25-hydroxy vitamin D level, longer timed up and go, and low short physical performance battery score (p<0.05). Physico-nutritional, psychological, sociodemographic, and medical factors are strongly associated with frailty.

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