scholarly journals Treatment-Related Dysgeusia in Oral and Oropharyngeal Cancer: A Comprehensive Review

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3325
Author(s):  
Lucrezia Togni ◽  
Marco Mascitti ◽  
Arianna Vignigni ◽  
Sonila Alia ◽  
Davide Sartini ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Patients ◽  
Neck Region ◽  
Common Side Effect ◽  
Case Control Studies ◽  
Cross Sectional ◽  
Comprehensive Review ◽  
Oncological Treatment ◽  
Oral Cancer Patients ◽  
Oral And Oropharyngeal Cancer

Oral cancer is the most common tumor of the head and neck region. Its management is based on surgical and systemic therapies. Taste disorders represent the most common side effect of these treatments; indeed, dysgeusia is noted by 70% of oral cancer patients. Despite survival remaining the primary endpoint of cancer patients, taste impairments can cause psychological distress. This comprehensive review describes the last decade’s knowledge from the literature regarding taste alterations in patients with oral and oropharyngeal squamous cell carcinoma. A total of 26 articles in English, including prospective, cross-sectional, and case–control studies, and clinical trials were evaluated. Literature analysis shows that anti-cancer treatments can destroy taste cells, decrease and alter their receptors, and interrupt nerve transmission. Furthermore, the tumour itself can destroy the oral mucosal lining, which encloses the taste buds. Dysgeusia typically occurs in 3–4 weeks of treatments, and usually taste sensation is recovered within 3–12 months. However, some patients exhibit incomplete or no recovery, even several years later. Thus, dysgeusia can become a chronic issue and negatively influence patients’ quality of life, worsening their dysphagia and their nutritional status. Physicians should be focused on preventing oncological treatment-related symptoms, offering the most suitable personalized support during therapy.

Factors associated with delay in presentation among patients for oral cancer

2019 ◽  
Vol 8 (12) ◽  
pp. 1003-1071
Author(s):  
Xinyan Zhang ◽  
Dongling Liu ◽  
Hongmei Dong ◽  
Yuxiang Li ◽  
Ye Zhang ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Patients ◽  
Lower Risk ◽  
Cross Sectional Study ◽  
Cancer Knowledge ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Factors Influencing ◽  
Oral Cancer Patients

Aim: This study aimed to determine factors that influence delay in presentation among oral cancer patients. Materials & methods: A cross-sectional study with 128 Oral cancer patients receiving treatment from the Hospital of Stomatology, at Jilin University, in China, was conducted. Results: A total of 78 patients delayed seeking treatment for more than 3 weeks after noticing symptoms of oral anomaly. Patients who were male, farmers (Odds ratio [OR] = 2.617; 95% CI: 1.90–3.64), or currently smoking (OR = 4.651; 95% CI: 1.21–9.46), were more likely to delay. Patients alerted to the problem at a physical exam had much lower risk of delay than patients who discovered the disease independently (OR = 0.029; 95% CI: 0.01–0.30). Higher coping style scores (OR = 0.747; 95% CI: 0.47–1.18) and oral cancer knowledge scores (OR = 0.886; 95% CI: 0.60–2.01) were significantly correlated with shorter delays. Conclusion: Delay in presentation may be achieved through regular oral health screening and improved public education about factors influencing delay.

Quality of life after different procedures for regional control in oral cancer patients: cross-sectional survey

2016 ◽  
Vol 41 (3) ◽  
pp. 228-233 ◽  
Author(s):  
T.M. Govers ◽  
W.H. Schreuder ◽  
W.M.C. Klop ◽  
J.P.C. Grutters ◽  
M.M. Rovers ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Cancer ◽  
Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Regional Control ◽  
Oral Cancer Patients

scholarly journals Effects of stigma, hope and social support on quality of life among Chinese patients diagnosed with oral cancer: A cross-sectional study

2020 ◽  
Author(s):  
Ying Zhang ◽  
Chun-Ying Cui ◽  
Yu Wang ◽  
Lie Wang
Keyword(s):  
Social Support ◽  
Oral Cancer ◽  
Cancer Patients ◽  
Perceived Social Support ◽  
Cross Sectional Study ◽  
Chinese Patients ◽  
Cross Sectional ◽  
Oral Cancer Patients ◽  
Medical University

Abstract Background Improving quality of life (QoL) has been one of the goals of health care for people living with oral cancer. This study aimed to assess QoL and investigate the effects of stigma, hope, and social support on QoL among Chinese oral cancer patients.Methods A cross-sectional study was conducted at the Department of Stomatology, Shengjing Hospital of China Medical University and Stomatology Hospital of China Medical University in Liaoning Province, China, between May 2016 and October 2017. A total of 230 oral cancer patients were recruited to complete a questionnaire including the Functional Assessment of Cancer Therapy-Head and Neck (FACT-H&N), the Social Impact Scale (SIS), the Herth Hope Index (HHI) and the Multidimensional Scale of Perceived Social Support (MSPSS). Univariate one-way ANOVA/t-test, Person’s r and hierarchical linear regression analysis were conducted to explore the factors influencing QoL and the relationships between stigma, hope, perceived social support and QoL.Results The mean QoL score was 90.85±20.15 among the patients with oral cancer. Stigma was negatively related to QoL, explaining 39.3% of the variance. In addition, hope and perceived social support were positively associated with QoL, explaining 8.1% of the variance.Conclusion Overall, Chinese patients with oral cancer suffer from low QoL. Stigma was significantly and negatively associated with QoL, while hope and perceived social support were positively associated with QoL. Oral cancer patients’ psychological states should be addressed, and adequate intervention based on positive psychological resources should be provided to improve the QoL of patients with oral cancer.

scholarly journals Effects of stigma, hope and social support on quality of life among Chinese patients diagnosed with oral cancer: A multi-center, cross-sectional study

2020 ◽  
Author(s):  
Ying Zhang ◽  
Chun-Ying Cui ◽  
Yu Wang ◽  
Lie Wang
Keyword(s):  
Social Support ◽  
Oral Cancer ◽  
Cancer Patients ◽  
Perceived Social Support ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Oral Cancer Patients ◽  
Medical University

Abstract BackgroundImprovement of quality of life (QoL) has been one of goals in health care for people living with oral cancer. This study aimed at assessing the QoL and investigate the effects of stigma, hope, social support on QoL among Chinese oral cancer patients. MethodsA multiple center cross-sectional study was conducted at the Department of Stomatology, Shengjing Hospital of China Medical University and Stomatology Hospital of China Medical University in Liaoning province, China between May 2016 and October 2017. A total of 230 oral cancer patients were recruited to complete a questionnaire including the Functional Assessment of Cancer Therapy-Head and Neck (FACT-H&N), the Social Impact Scale (SIS), the Herth Hope Index (HHI) and the Multidimensional Scale of Perceived Social Support (MSPSS). Univariate one-way ANOVA/t-test, Person’s r and hierarchical linear regression analysis were conducted to explore the influence factors of QoL and the relationships between stigma, hope, perceived social support and QoL. ResultsThe mean QoL score was 90.85±20.15 among the patients with oral cancer. Stigma was negatively related to QoL, explaining 39.3% of the variance. In addition, hope and perceived social support were positively associated with QoL, explaining 8.1% of the variance.ConclusionOverall, Chines patients with oral cancer are suffering from a relatively low level of QoL. Stigma was significantly and negatively associated with QoL, while hope and perceived social support were positively associated with QoL. Oral cancer patients’ psychological status should be addressed and adequate intervention based on positive psychological resources should be provided to improve the QoL of patients with oral cancer.

scholarly journals A clinico-epidemiological hospital based study of oral cancer patients in Gwalior district

2021 ◽  
Vol 8 (2) ◽  
pp. 132-138
Author(s):  
Ankita Tripathi ◽  
Anil Kumar Agarwal ◽  
Ramniwas Mahore ◽  
Sumit S Bhadoriya ◽  
Swati Saraswat
Keyword(s):  
Oral Cancer ◽  
Oral Cavity ◽  
Cancer Patients ◽  
Indian Subcontinent ◽  
Tobacco Consumption ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
Common Cancer ◽  
Oral Cancer Patients

Oral cancer is the most common form of carcinoma of oral cavity and ranks as the 12th most common cancer in the world. Oral cancer is one of the major social & health problems in India and Indian subcontinent countries. Tobacco use in different forms is the main etiological factor for oral carcinoma. (i) To define relations of oral cancer with respect to gender, age group, socioeconomic status and risk habits; (ii) To observe the distribution of affected oral cavity sites and observe the clinical profile in oral cancer patients. A cross-sectional study of 340 oral cancer patients from January 2019 to December 2019 was carried out in Department of oncology & radiotherapy, JA Group of hospital, G. R. Medical Gwalior, Madhya Pradesh India. Details of patient's sex, age, tobacco habit and site of cancer and status were noted. Data were analyzed by probability of patient with risk factors and chi-squire (χ) test. The prevalence of oral cancer was significantly (p < 0.001) higher in males (91.5.9%) than females (8.5%). In both the sexes, most affected sites were the buccal mucosa and gingivo-buccal sulcus. However, the consuming form of tobacco was found to be significantly associated with oral cancer, in both sex. The study revealed that oral cancer is more common in men, probably due to habit of large tobacco consumption.

scholarly journals Time span from onset of oral cancer symptoms to treatment: a hospital based cross sectional study in South India

2018 ◽  
Vol 5 (12) ◽  
pp. 5082
Author(s):  
Shivaraj Nallur Somanna ◽  
Nandakumar Bidare Sastry ◽  
Ramesh Cheluvarayaswamy ◽  
K. S. Sabitha ◽  
Murthy Nandagudi Srinivasa ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Medical Care ◽  
Cancer Patients ◽  
Median Time ◽  
Cross Sectional Study ◽  
Time Span ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cancer Symptoms ◽  
Oral Cancer Patients

Background: Oral cancer is one of the major health problems in India. Patient delay in seeking medical help usually contributes to late stage at diagnosis, high mortality and low survival. Our study aims to find the time span from first onset of oral cancer symptoms to cancer specific primary treatment.Methods: A cross-sectional study was carried out from October 2015-September 2016 in one of the tertiary care cancer center in Bangalore. Histopathologically confirmed 212 incident oral cancer patients were interviewed using a pre-tested semi structured questionnaire.Results: The median time span between onset of symptoms and seeking medical care was 60 [IQR 30, 104] days, the median time between seeking medical care and diagnosis was 30 [IQR 15, 90] days, and the median time between diagnosis and initiation of treatment was 20 [IQR 12, 33] days.Conclusions: There is considerable delay in seeking cancer specific primary treatment among oral cancer patients. Efforts should be undertaken to increase awareness in the population and all stakeholders regarding symptoms and improve early diagnostics and access to care.

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