scholarly journals Uncovering the First Atypical DS-1-like G1P[8] Rotavirus Strains That Circulated during Pre-Rotavirus Vaccine Introduction Era in South Africa

Pathogens ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 391 ◽  
Author(s):  
Peter N. Mwangi ◽  
Milton T. Mogotsi ◽  
Sebotsana P. Rasebotsa ◽  
Mapaseka L. Seheri ◽  
M. Jeffrey Mphahlele ◽  
...  

Emergence of DS-1-like G1P[8] group A rotavirus (RVA) strains during post-rotavirus vaccination period has recently been reported in several countries. This study demonstrates, for the first time, rare atypical DS-1-like G1P[8] RVA strains that circulated in 2008 during pre-vaccine era in South Africa. Rotavirus positive samples were subjected to whole-genome sequencing. Two G1P[8] strains (RVA/Human-wt/ZAF/UFS-NGS-MRC-DPRU1971/2008/G1P[8] and RVA/Human-wt/ZAF/UFS-NGS-MRC-DPRU1973/2008/G1P[8]) possessed a DS-1-like genome constellation background (I2-R2-C2-M2-A2-N2-T2-E2-H2). The outer VP4 and VP7 capsid genes of the two South African G1P[8] strains had the highest nucleotide (amino acid) nt (aa) identities of 99.6–99.9% (99.1–100%) with the VP4 and the VP7 genes of a locally circulating South African strain, RVA/Human-wt/ZAF/MRC-DPRU1039/2008/G1P[8]. All the internal backbone genes (VP1–VP3, VP6, and NSP1-NSP5) had the highest nt (aa) identities with cognate internal genes of another locally circulating South African strain, RVA/Human-wt/ZAF/MRC-DPRU2344/2008/G2P[6]. The two study strains emerged through reassortment mechanism involving locally circulating South African strains, as they were distinctly unrelated to other reported atypical G1P[8] strains. The identification of these G1P[8] double-gene reassortants during the pre-vaccination period strongly supports natural RVA evolutionary mechanisms of the RVA genome. There is a need to maintain long-term whole-genome surveillance to monitor such atypical strains.

1980 ◽  
Vol 10 (3-4) ◽  
pp. 77-80 ◽  
Author(s):  
D. Rajab ◽  
E.A. Chohan

The Rosenzweig P — F Study was administered to a group of South African Indian students (N = 403) from the University of Durban-Westville with slight modifications in administration. The subjects were divided into three groups and were instructed to react to Blacks in Group A, to Whites in Group B, and to Indians in Group C. The results indicated that the subjects differed in their responses to the three racial groups revealing predominantly intropunitive and impunitive responses to Blacks, and extrapunitive responses to Indians.


1983 ◽  
Vol 120 (1) ◽  
pp. 51-58 ◽  
Author(s):  
A. J. Boucot ◽  
C. H. C. Brunton ◽  
J. N. Theron

SummaryThe Devonian brachiopod Tropidoleptus is recognized for the first time in South Africa. It is present in the lower part of the Witteberg Group at four widely separated localities. Data regarding the stratigraphical range of the genus elsewhere, combined with information on recently described fossil plants and vertebrates from underlying strata of the upper Bokkeveld Group, suggest that a Frasnian or even Givetian age is reasonable for the lower part of the Witteberg Group. The recognition of Tropidoleptus in a shallow water, near-shore, molluscan association, at the top of the South African marine Devonian sequence, is similar to its occurrence in Bolivia, and suggests a common Malvinokaffric Realm history of shallowing, prior to later Devonian or early Carboniferous non-marine sedimentation. It is noteworthy that Tropidoleptus is now known to occur in ecologically suitable environments around the Atlantic, but is absent from these same environments in Asia and Australia. Tropidoleptus is an excellent example of dispersal in geological time — first appearing in northern Europe and Nova Scotia, then elsewhere in eastern North America and North Africa, followed by South America and South Africa, while continuing in North America.


2017 ◽  
Vol 113 (7/8) ◽  
Author(s):  
Nelson A. F. Miranda ◽  
Nasreen Peer ◽  
Renzo Perissinotto ◽  
Nicola K. Carrasco ◽  
Salome Jones ◽  
...  

The thick-shelled clam Meretrix morphina, previously referred to as Meretrix meretrix, now occurs in the west Indian Ocean region, along the eastern seaboard of Africa, from the Red Sea to the Mlalazi Estuary, close to the Tugela River. Its presence in South Africa is only of recent recording. Meretrix morphina was detected for the first time in Lake St Lucia in 2000. The population declined and was not detected from 2005 until 2011, most likely as a result of a severe drought that resulted in widespread desiccation and hypersalinity in the lake. The system then experienced increased freshwater input resulting in lower salinities from 2011 until 2014, during which time M. morphina reappeared and their population gradually increased. In 2015, M. morphina became abundant in St Lucia, attaining unprecedented densities of 447 ind./m2. Biomass, expressed as a fresh weight, varied in the different basins of St Lucia, ranging from 195 g/m2 at Lister’s Point to 1909.8 g/m2 at Catalina Bay. However, in 2016, when drought conditions returned, M. morphina disappeared. This species appears to thrive under brackish salinities and high temperatures. It is able to establish large populations with high biomass and can become dominant. However, M. morphina is sensitive to desiccation and hypersaline conditions. This clam has substantial commercial value and is exploited along the African east coast, particularly in Mozambique. In future, it may feature more prominently in South African estuaries. However, the ecology of M. morphina is still largely unknown.


Bothalia ◽  
1971 ◽  
Vol 10 (3) ◽  
pp. 411-416 ◽  
Author(s):  
W. F. O. Marasas ◽  
G. C. A. Van der Westhuizen

Four species of fungi recorded for the first time in South Africa, are described and illustrated. These are:  Acremoniella verrucosa  Togn. from roots of  Medicago sativa; Coniella pulchella Hohn. from roots of pine-apple;  Periconia igniaria  Mason Ellis from seed of  Medicago sativa;  and  Stachybotrys subsimplex  Cooke from the cocoon of  Parastizopus armaticeps.


Zootaxa ◽  
2019 ◽  
Vol 4577 (2) ◽  
pp. 361
Author(s):  
JIŘÍ JANÁK

A revision of the south African genus Neopimus Özdikmen, Demir & Türkeş, 2008 is presented. Based on revision of the type and additional material, three species are recognised. The genus Neopimus is redescribed and all species are described or redescribed and illustrated, two of them for the first time: Neopimus capensis Janák, sp. nov., from Eastern Cape Province, South Africa and N. zulu Janák, sp. nov., from KwaZulu-Natal Province, South Africa. The distribution of the genus is mapped and a key of species is presented. 


Zootaxa ◽  
2020 ◽  
Vol 4820 (1) ◽  
pp. 70-104
Author(s):  
PRECIOUS TSHILILO

Euryphyminae is a Southern African endemic subfamily, which to date consists of 23 genera. We collected all available information from historic literature accounts, 626 positively identified museum specimens from 16 genera and 624 fresh field-collected specimens from eight genera to review the Euryphyminae genera of South Africa. Three genera are recorded for the first time to occur in South Africa; Rhodesiana Dirsh, 1959, Acrophymus Uvarov, 1922 and Plegmapteropsis Dirsh, 1956, while Aneuryphymus rhodesianus species is also recorded for the first time in South Africa. This brings the total number of genera occurring in South Africa from 14 to 16 genera of Euryphyminae. Finally, distribution maps for each genus are provided along with an updated key to genera.


2015 ◽  
Vol 3 (6) ◽  
Author(s):  
Kgaugelo E. Lekota ◽  
Joseph Mafofo ◽  
Evelyn Madoroba ◽  
Jasper Rees ◽  
Henriette van Heerden ◽  
...  

Bacillus anthracis is a Gram-positive bacterium that causes anthrax, mainly in herbivores through exotoxins and capsule produced on plasmids, pXO1 and pXO2. This paper compares the whole-genome sequences of two B. anthracis strains from an endemic region and a sporadic outbreak in South Africa. Sequencing was done using next-generation sequencing technologies.


Author(s):  
K. Nomikou ◽  
S. Maan ◽  
N. S. Maan ◽  
P. P.C. Mertens

Bluetongue virus (BTV) is the prototype species of the genus Orbivirus within the family Reoviridae. There are 24 (possibly 25) distinct serotypes of BTV, eleven of which have entered, or have been identified in Europe and the Mediterranean region since 1998 (types 1, 2, 4, 6, 8, 9, 11, 15, 16, 24 and 25). The first BTV to arrive in Greece during 1998 was serotype 9 (iso­late GRE1998/01), followed by BTV-16 (GRE1999/13) during 1999. BTV-9 spread to mainland Greece, South-Eastern Bulgaria and European Turkey during 1999, to Italy during 2000, then to Serbia, Montenegro, Kosovo, Macedonia, Bulgaria, Croatia, mainland Italy and Sicily in 2001. In 2002, BTV-9 was again identified in Bosnia, Bulgaria, Montenegro, Yugoslavia and Albania, and was identified in Libya for the first time in 2008. The whole genome was sequenced for representative field and vaccine strains of BTV-9 and 16 from the Mediterranean region, identifying the levels of genetic heterogeneity in each genome segment. The early European isolates of BTV-9 (1998 onwards) were identified as ‘eastern’ strains related to those from India, Indonesia and Australia. BTV-16 isolates are also eastern strains that are most closely related to strains from Turkey and the South African reference strain of type 16 (originally from Pakistan). Analyses of the more conserved genome segments coding for structural and non-structural proteins of BTV-9 (from Bosnia, Bulgaria, Greece and Turkey) and BTV-16 (from Greece and Turkey) show that the Eastern European isolates of these two serotypes have the remaining eight genome segments (1, 3, 4, 5, 7, 8, 9 and 10) with more than 99% similarity, in each case belonging to the same eastern lineage. These data show that the BTV-9 and 16 isolates that were circulating in the Mediterranean region are reassortants, with the majority of their genome seg­ments derived from a single parental lineage. However, the BTV-9 isolate from Libya (LIB2008/08) is more closely related to the western BTV-9 reference strain from South Africa than to the earlier BTV-9 isolates from Eastern Europe. Analysis of the more conserved segments of LIB2008/08 showed only 79.8–80.2% similarity with the eastern European BTV-9 isolates from the Eastern Mediterranean region, but 89–93.5% similarity with the BTV-9 reference and vaccine strains from South Africa. BTV-9 from Libya belongs to a distinct western lineage of viruses and represents both a new introduction to the Mediterranean region and a new threat to Europe.


Author(s):  
Martin P. Botha

INTRODUCTIONThe name, Manie van Rensburg, is virtually unknown in Europe and the United States of America. Recently, some of his work was screened at a South African film festival in Amsterdam at the Kriterion cinema and I had the honour to present a lecture there on 7 October 1995 regarding Van Rensburg and his presence in the cinema. His film work was also highlighted in a small retrospective during October 1996 at the Vrije Universiteit Brussel. IT WAS NOT THE FIRST TIME a Van Rensburg film was screened outside the borders of South Africa. During the 1980s Van Rensburg received an International Film Festival of New York award for his historical TV drama series, Heroes, and a Merit Award from the London Film Festival was given to him for his filmed play, The Native who Caused all the Trouble. His mammoth production, The Fourth...


2013 ◽  
Vol 6 (2) ◽  
pp. 263-284
Author(s):  
Sharon Smulders ◽  
Gelishan Naidoo

Small businesses have the potential to grow the economy, generate jobs and reduce poverty, but they face many constraints including high tax compliance costs and burdens. A comparison of the findings and recommendations made in small business tax compliance cost studies conducted in South Africa with initiatives introduced by the South African Revenue Service (SARS), substantiated by consultations with a SARS and a South African Institute of Chartered Accountants official, reveals that SARS has, in most cases, attempted to address the tax compliance burdens identified in these studies. However, SARS has only partially addressed the complexity of the tax law, the lack of software to assist small businesses with their record-keeping and the compliance burden associated with provisional tax. SARS has failed to address the need for a threshold below which no small business tax return is required to be submitted, the inclusion of tax in the school syllabus, the requirement for first-time offenders to attend courses instead of raising penalties and the need for a reduction in the rates of interest and penalties raised by SARS. These initiatives should be considered by SARS and it is recommended that further research into the success and effectiveness of all the initiatives already introduced by SARS be performed.


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