scholarly journals Silica-Based Bioactive Glasses and Their Applications in Hard Tissue Regeneration: A Review

2021 ◽  
Vol 14 (2) ◽  
pp. 75
Author(s):  
Nuha Al-Harbi ◽  
Hiba Mohammed ◽  
Yas Al-Hadeethi ◽  
Ahmed Samir Bakry ◽  
Ahmad Umar ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Tissue Regeneration ◽  
The Body ◽  
Bone Tissue Regeneration ◽  
Hard Tissue ◽  
Bioactive Glasses ◽  
Bioactive Materials ◽  
Glass Forming ◽  
Content Ratio ◽  
Implant Coatings

Regenerative medicine is a field that aims to influence and improvise the processes of tissue repair and restoration and to assist the body to heal and recover. In the field of hard tissue regeneration, bio-inert materials are being predominantly used, and there is a necessity to use bioactive materials that can help in better tissue–implant interactions and facilitate the healing and regeneration process. One such bioactive material that is being focused upon and studied extensively in the past few decades is bioactive glass (BG). The original bioactive glass (45S5) is composed of silicon dioxide, sodium dioxide, calcium oxide, and phosphorus pentoxide and is mainly referred to by its commercial name Bioglass. BG is mainly used for bone tissue regeneration due to its osteoconductivity and osteostimulation properties. The bioactivity of BG, however, is highly dependent on the compositional ratio of certain glass-forming system content. The manipulation of content ratio and the element compositional flexibility of BG-forming network developed other types of bioactive glasses with controllable chemical durability and chemical affinity with bone and bioactivity. This review article mainly discusses the basic information about silica-based bioactive glasses, including their composition, processing, and properties, as well as their medical applications such as in bone regeneration, as bone grafts, and as dental implant coatings.

Bioglass at 50 – A look at Larry Hench’s legacy and bioactive materials

2019 ◽  
Vol 5 (1) ◽  
pp. 178-184 ◽  
Author(s):  
David Greenspan
Keyword(s):  
Bioactive Glass ◽  
The Body ◽  
Inorganic Materials ◽  
Bioactive Glasses ◽  
Bioactive Materials ◽  
Bone Replacement Material ◽  
Bone Replacement ◽  
Young Professor

Abstract In 1969, fifty years ago, a young professor of ceramic engineering created a 4-component glass to be used as a bone replacement material. That material became known as “Bioglass” and more generally as a class of materials known as bioactive glass. Those first experiments conducted by Dr. Larry Hench completely shifted the paradigm of how the biomaterials and medical communities look at the interactions between inorganic materials and tissues in the body. This article will touch on just a few highlights of the development of bioactive glasses and relate those to the concepts of bioactivity and tissue bonding.

scholarly journals Bioactıve Glass‐Polymer Nanocomposites for Bone Tıssue Regeneration Applicatıons: A Revıew

2019 ◽  
Vol 21 (8) ◽  
pp. 1900287 ◽  
Author(s):  
Melek Erol‐Taygun ◽  
Irem Unalan ◽  
Maizlinda Izwana Binti Idris ◽  
João F. Mano ◽  
Aldo R. Boccaccini
Keyword(s):  
Bioactive Glass ◽  
Bone Tissue ◽  
Polymer Nanocomposites ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration

A highly bioactive and biodegradable poly(glycerol sebacate)–silica glass hybrid elastomer with tailored mechanical properties for bone tissue regeneration

2015 ◽  
Vol 3 (16) ◽  
pp. 3222-3233 ◽  
Author(s):  
Xin Zhao ◽  
Yaobin Wu ◽  
Yuzhang Du ◽  
Xiaofeng Chen ◽  
Bo Lei ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bioactive Glass ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Silica Glass ◽  
Bone Tissue Regeneration ◽  
Biodegradable Poly

A highly bioactive and biodegradable PGS–Silica bioactive glass hybrid elastomer with tailored mechanical properties was developed for bone tissue regeneration application.

Hierarchically mesoporous-macroporous bioactive glasses scaffolds for bone tissue regeneration

2008 ◽  
Vol 87B (2) ◽  
pp. 374-380 ◽  
Author(s):  
Hui-suk Yun ◽  
Seung-eon Kim ◽  
Yong-taek Hyun ◽  
Su-jin Heo ◽  
Jung-wook Shin
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Bioactive Glasses

Preparation of an rhBMP-2 loaded mesoporous bioactive glass/calcium phosphate cement porous composite scaffold for rapid bone tissue regeneration

2015 ◽  
Vol 3 (43) ◽  
pp. 8558-8566 ◽  
Author(s):  
Nan Li ◽  
Chuan Jiang ◽  
Xingdi Zhang ◽  
Xinfeng Gu ◽  
Jingwei Zhang ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bioactive Glass ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Calcium Phosphate Cement ◽  
Composite Scaffold ◽  
Early Stage ◽  
Bone Tissue Regeneration ◽  
Porous Composite ◽  
Mesoporous Bioactive Glass

An rhBMP-2/MBG/CPC scaffold is beneficial for rapid bone tissue regeneration in the early stage.

Biomorphic Silicon Carbide Ceramics Coated with Bioactive Glass for Medical Applications

2006 ◽  
Vol 514-516 ◽  
pp. 970-974 ◽  
Author(s):  
Jacinto P. Borrajo ◽  
Pio González ◽  
Julia Serra ◽  
Sara Liste ◽  
Stefano Chiussi ◽  
...  
Keyword(s):  
Silicon Carbide ◽  
Bioactive Glass ◽  
The Body ◽  
Bioactive Materials ◽  
Bioactive Coatings ◽  
Metallic Substrates ◽  
New Material ◽  
Carbide Ceramics ◽  
Silicon Carbide Ceramics

There is a need to develop new tough bioactive materials capable to withstand high loads when implanted in the body and with improved fixation, which led to the production of bioactive coatings on metallic substrates. A new approach, which consists of biomorphic silicon carbide (SiC) coated with bioactive glass, was recently presented. This new material joins the high mechanical strength, lightness and porosity of biomorphic SiC, and the bioactive properties of PLD glass films. In this work, a multiple evaluation in terms of biocompatibility of this new material was carried out starting from the biomorphic SiC morphology and porosity, following with the bioactivity of the coatings in simulated body fluid, and ending with a deep biocompatibility study with MG-63 cells. Different ranges of porosity and pore size were offered by the biomorphic SiC depending on the starting wood. The PLD glassy coatings had a high bioactivity in vitro and both the biomorphic SiC coated and uncoated presented high levels of biocompatibility.

scholarly journals Strontium-releasing mesoporous bioactive glasses with anti-adhesive zwitterionic surface as advanced biomaterials for bone tissue regeneration

2020 ◽  
Vol 563 ◽  
pp. 92-103 ◽  
Author(s):  
Carlotta Pontremoli ◽  
Isabel Izquierdo-Barba ◽  
Giorgia Montalbano ◽  
María Vallet-Regí ◽  
Chiara Vitale-Brovarone ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Bioactive Glasses ◽  
Advanced Biomaterials
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