scholarly journals Report on Webinar Series Cell and Gene Therapy: From Concept to Clinical Use

Pharmaceutics ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 168
Author(s):  
Christopher F. van der Walle ◽  
Christine Dufès ◽  
Arpan S. Desai ◽  
Julie Kerby ◽  
Joanne Broadhead ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Annual Growth Rate ◽  
Pharmaceutical Sciences ◽  
The European Union ◽  
Clinical Implementation ◽  
Compound Annual Growth Rate ◽  
Advanced Therapy ◽  
Challenges And Opportunities ◽  
Cell And Gene Therapy ◽  
The Uk

With the launch of the UK Academy of Pharmaceutical Sciences Advanced Therapy Medicinal Products Focus Group in late 2020, a webinar series reviewing the current and emerging trends in cell and gene therapy was held virtually in May 2021. This webinar series was timely given the recent withdrawal of the United Kingdom from the European Union and the global COVID-19 pandemic impacting all sectors of the pharmaceutical sciences research landscape globally and in the UK. Delegates from the academic, industry, regulatory and NHS sectors attended the session where challenges and opportunities in the development and clinical implementation of cell and gene therapies were discussed. Globally, the cell and gene therapy market has reached a value of 4.3 billion dollars in 2020, having increased at a compound annual growth rate of 25.5% since 2015. This webinar series captured all the major developments in this rapidly evolving area and highlighted emerging concepts warranting cross-sector efforts from across the community in the future.

scholarly journals Retail Payments Strategy for the EU versus the challenges of the payment sector

2021 ◽  
Vol 20 (3) ◽  
pp. 617-640
Author(s):  
Michał Polasik ◽  
Paweł Widawski ◽  
Grzegorz Keler ◽  
Agnieszka Butor-Keler
Keyword(s):  
The European Union ◽  
Eu Member States ◽  
The Future ◽  
Challenges And Opportunities ◽  
Depth Study ◽  
Payments Systems ◽  
Payment Services ◽  
The Uk ◽  
Retail Payments ◽  
The Eu

Motivation: The payment services sector has become one of the main areas for the development of financial innovation and the key element of the digital economy. However, the payment services market in the European Union (called the European Payments Market) is still fragmented along national borders, insufficiently integrated, and facing several challenges. Therefore, the newly announced Retail Payments Strategy for the EU is a document of great importance for the future of the entire EU economy, and deserves in-depth study. Aim: The purpose of this paper is to assess whether the trends and challenges identified by the European Commission in the Retail Payments Strategy, and the general directions and proposed actions presented in this document, appropriately reflect the challenges faced by the European payment market. Results: A comparative analysis of the Strategy’s assumptions and proposed actions was conducted, in relation to the identified challenges of the payment sector. The empirical data were derived from a survey of 202 experts from all EU member states, and the UK, Norway and Switzerland, covering all types of bank and non-bank payment market players. The analysis confirmed that the Strategy identified the main challenges and opportunities, in line with the results of the expert survey: the need for further development of open banking; cross-border integration and development of instant payments systems; and ensuring access to the banking payment infrastructure, including contactless and NFC mobile payments. However, the proposed directions of action in selected areas have not been sufficiently rationalised, and most of the actions have been left to be specified in the future. In addition, the Strategy relies mostly on the use of regulatory tools that may limit innovativeness. Although the Commission and the surveyed experts agreed in recognising the challenges related to the increasing role of BigTechs in the payment sector, no comprehensive solution addressing the related challenges was proposed in the Strategy.

scholarly journals Study the challenges and opportunities of agricultural development of Bundelkhnad Region.

2018 ◽  
Vol 33 (4) ◽  
Author(s):  
Sanjeev Kumar ◽  
Sanjay Kumar Upadhyay
Keyword(s):  
Agricultural Development ◽  
Agricultural Research ◽  
Secondary Data ◽  
State Level ◽  
Annual Growth Rate ◽  
Compound Annual Growth Rate ◽  
Agriculture Sector ◽  
Agricultural Diversification ◽  
Challenges And Opportunities ◽  
The Government

This study analyses the changes of agriculture sector in Bundelkhand region during 2000-01 to 2015-16 by using secondary data. The Compound Annual Growth Rate (CAGR) and Risk Instability Index (RII) techniques have been used to study the the ternds of agricultural development and risk in agriculture. It is found from the analysis that there are widespread variations in the area, production, productivty of crops in Bundelkhnad region. In spite of this, there is high fluctuations have been witneesed in the average productivty of the crops at regional and state level. Moreover, the agricultiral development of Bundelkhad region has been faced the instability condition due to the continious increase in crop risk. Therefor, the government should be emphasied on development of irrigation facility, agricultural diversification, expenssion of credit facility, investment on agricultural research, use of modern agricultural techinique and climatic resilient technology to achieve sutainable development of Bundelkhnmad region.

"Assessment of global halal market : challenges and opportunities"

2020 ◽  
Vol 15 (4) ◽  
pp. 5-23
Author(s):  
Hafiz Wasim Akram ◽  
Keyword(s):  
Growth Rate ◽  
Annual Growth ◽  
Market Size ◽  
Annual Growth Rate ◽  
Secondary Research ◽  
Compound Annual Growth Rate ◽  
Global Consensus ◽  
The Us ◽  
Challenges And Opportunities ◽  
The Status

This study presents the status of the burgeoning global halal market, challenges it faces, and opportunities available for stakeholders. The study is based on primary and secondary research, and found that the US$2.1trillion halal market is projected to reach US $3 trillion by the end of 2023 at a compound annual growth rate of 6.11 per cent. The present market size will more than double if Islamic financing is brought under the ambit of the halal market. Though the uncharted territory has a lot of potential to be tapped, it is also afflicted with multifaceted challenges such asa lack of global consensus (ijama).It is recommended that a harmonized system (HS)code-like mechanism be adopted to capture trade figures of products that conform to halal principles.

Low-Skilled Employment in a New Immigration Regime: Challenges and Opportunities for Business Transitions

2019 ◽  
Vol 248 ◽  
pp. R17-R27
Author(s):  
Anne Green
Keyword(s):  
European Union ◽  
Migrant Workers ◽  
Business Models ◽  
Substantial Proportion ◽  
Free Movement ◽  
The European Union ◽  
Challenges And Opportunities ◽  
Ready Access ◽  
The Uk

In an era of free movement UK employers have had ready access to a supply of labour from the European Union to fill low-skilled jobs. This has enabled them to adopt business models, operating within broader supply chains, that take advantage of this source of labour and the flexibility that many migrant workers – especially those who are new arrivals to the UK – are prepared to offer them. Drawing mainly on evidence from employers on the role of migrant workers in selected sectors with a substantial proportion of low-skilled jobs, this article explores the challenges and opportunities they face in transitioning to a new post-Brexit immigration regime.

Scottish reform of the town and country planning system; Is it too little too late for post-Brexit Scotland?

2017 ◽  
Vol 19 (4) ◽  
pp. 239-243
Author(s):  
Anne-Michelle Slater
Keyword(s):  
Environmental Law ◽  
Planning System ◽  
The European Union ◽  
The United Kingdom ◽  
Challenges And Opportunities ◽  
System Of Plan ◽  
Social Environmental ◽  
The Uk ◽  
The Town ◽  
Country Planning

The call for planning reform is never far from politicians’ lips as a solution to economic, social environmental and other problems in all parts of the UK. A planning Bill will be considered by the Scottish Parliament in the 2017–2018 session and modest reforms to the existing system of plan creation are expected. This opinion considers the planning system in Scotland at a time of inevitable change in environmental law due to Brexit. It concludes that a clearer and more open view of what used to be known as the town and country planning system needs to be adopted. This is required not only to bring about effective change on the ground but also to address the challenges and opportunities of the United Kingdom leaving the European Union.

Attenuating Muscle Wasting: Cell and Gene Therapy Approaches

2003 ◽  
Vol 4 (7) ◽  
pp. 575-585 ◽  
Author(s):  
A. Musaro ◽  
N. Rosenthal
Keyword(s):  
Gene Therapy ◽  
Muscle Wasting ◽  
Cell And Gene Therapy

Assessment of Gaming Practices and its effect on scholastic performance of medical students in India: A Case Control study. (Preprint)

2020 ◽  
Author(s):  
Deodatt Madhav Suryawanshi ◽  
Divya Rajaseharan 2nd ◽  
Raghuram Venugopal 3rd ◽  
Ramchandra Goyal 4th ◽  
Anju Joy 5th
Keyword(s):  
Medical Students ◽  
Case Control ◽  
Annual Growth Rate ◽  
Gaming Addiction ◽  
Gaming Disorder ◽  
Compound Annual Growth Rate ◽  
Internal Assessment ◽  
Assessment Scores ◽  
Scholastic Performance ◽  
Excessive Gaming

BACKGROUND Introduction: Gaming is a billion-dollar industry growing at a Compound annual growth rate (CAGR) of 9 %- 14.3% with biggest market in South East Asian countries. Availability of Low-cost smart phones, ease of internet access has made gaming popular among youth who enjoy it as a leisure activity. According to the WHO excessive indulgence in Gaming can lead to Gaming disorder. Medical students indulging in excessive gaming can succumb to gaming disorder which can affect their scholastic performance. Hence this study was done to assess the gaming practices and its effect on scholastic performance. OBJECTIVE Objective: 1. To assess the various Gaming practices and the Prevalence of Gaming addiction among medical students. 2. To study the effect of Gaming practices on Scholastic performance of medical students. METHODS Methods: The present study used a case control design where the 448(N) study participants were recruited using non probability sampling technique.91 (Nc) cases who were Gaming for past 6 months were identified using rapid preliminary survey .91 controls (Nco) who never played games were selected and matched for age and sex. Internal Assessment scores (%) of cases and controls were compared. Snedecor F test and Student t test were used to find out the association between the hours of gaming and internal assessment scores (%) and difference of Internal assessment scores between cases and controls respectively. Odds ratio was calculated to identify the risk of Poor scholastic performance. Prevalence of Gaming addiction was assessed using Lemmen’s Gaming addiction scale (GAS). RESULTS Results: Frequency of gaming (hrs) was not associated with the Mean internal assessment scores (p>0.05). Male students (cases) showed significant reduction in both their internal assessment scores (p<0.001,<0.01) whereas no reduction was observed in Female cases. A negative correlation was observed between GAS and internal assessment scores (r=-0.02). Prevalence of Gaming addiction using GAS was found to be 6.2% among the study population(N=448) and 31% among Cases (Nc=91).The risk of low scores was (OR =1.80-1.89) times more in cases than controls. CONCLUSIONS Conclusions: Excessive Gaming adversely affects scholastic performance in males than females.Awareness about Gaming addiction needs to be created among students, parents and teachers. Institutionalized De-addiction services should be made available to medical students. CLINICALTRIAL No

The Law & Politics of Brexit: Volume II

2020 ◽  
Keyword(s):  
Decision Making ◽  
European Union ◽  
Legal Framework ◽  
Comprehensive Analysis ◽  
The European Union ◽  
Trade Relations ◽  
The United Kingdom ◽  
The Uk ◽  
Financial Settlement ◽  
The Eu

This book provides the first comprehensive analysis of the withdrawal agreement concluded between the United Kingdom and the European Union to create the legal framework for Brexit. Building on a prior volume, it overviews the process of Brexit negotiations that took place between the UK and the EU from 2017 to 2019. It also examines the key provisions of the Brexit deal, including the protection of citizens’ rights, the Irish border, and the financial settlement. Moreover, the book assesses the governance provisions on transition, decision-making and adjudication, and the prospects for future EU–UK trade relations. Finally, it reflects on the longer-term challenges that the implementation of the 2016 Brexit referendum poses for the UK territorial system, for British–Irish relations, as well as for the future of the EU beyond Brexit.

scholarly journals Advancing UK Regulatory Science Strategy in the Context of Global Regulation: a Stakeholder Survey

2021 ◽  
Author(s):  
Samantha Cruz Rivera ◽  
Barbara Torlinska ◽  
Eliot Marston ◽  
Alastair K. Denniston ◽  
Kathy Oliver ◽  
...  
Keyword(s):  
Pay For Performance ◽  
Regulatory Science ◽  
International Strategy ◽  
Free Text ◽  
The European Union ◽  
Accurate Definition ◽  
Definition Of ◽  
Healthcare Innovation ◽  
The Uk ◽  
Medium Enterprises

Abstract Background The UK’s transition from the European Union creates both an urgent need and key opportunity for the UK and its global collaborators to consider new approaches to the regulation of emerging technologies, underpinned by regulatory science. This survey aimed to identify the most accurate definition of regulatory science, to define strategic areas of the regulation of healthcare innovation which can be informed through regulatory science and to explore the training and infrastructure needed to advance UK and international regulatory science. Methods A survey was distributed to UK healthcare professionals, academics, patients, health technology assessment agencies, ethicists and trade associations, as well as international regulators, pharmaceutical companies and small or medium enterprises which have expertise in regulatory science and in developing or applying regulation in healthcare. Subsequently, a descriptive quantitative analyses of survey results and directed thematic analysis of free-text comments were applied. Results Priority areas for UK regulatory science identified by 145 participants included the following: flexibility: the capability of regulations to adapt to novel products and target patient outcomes; co-development: collaboration across sectors, e.g. patients, manufacturers, regulators, and educators working together to develop appropriate training for novel product deployment; responsiveness: the preparation of frameworks which enable timely innovation required by emerging events; speed: the rate at which new products can reach the market; reimbursement: developing effective tools to track and evaluate outcomes for “pay for performance” products; and education and professional development. Conclusions The UK has a time-critical opportunity to establish its national and international strategy for regulatory science leadership by harnessing broader academic input, developing strategic cross-sector collaborations, incorporating patients’ experiences and perspectives, and investing in a skilled workforce.

scholarly journals “East” in Europe—Health Dimension through the Lens of the UK Daily Mail and Statistical Facts

2021 ◽  
Vol 18 (7) ◽  
pp. 3705
Author(s):  
Izabella Lecka ◽  
Viktoriya Pantyley ◽  
Liudmila Fakeyeva ◽  
Alexandrina Cruceanu
Keyword(s):  
Care Practice ◽  
The European Union ◽  
Daily Mail ◽  
Media Criticism ◽  
The United Kingdom ◽  
Health Dimension ◽  
European Immigrants ◽  
The Uk ◽  
Zero Sum ◽  
Eastern European Immigrants

The study concerns the relationship between health and geopolitics in the United Kingdom (UK). To demonstrate this relationship, we examined the subject and tone of articles published in the popular media (on the example of tabloid the Daily Mail) in 2006–2020 concerning health and medical care, and the health and health care practice of Eastern European immigrants belonging to and not belonging to the European Union (EU). There was an increase in media criticism of the behaviour of immigrants in the years 2014–2017, in the period around the referendum in favour of the UK leaving the EU (Brexit). Attention was drawn to the media’s use of a Belief in a Zero-Sum Game (BZSG) narrative at that time. On both sides, “hosts” and the “guests”, a progressive anomy process was observed, degrading the behaviour of individuals and social groups.

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