scholarly journals Plant Sulfate Transporters in the Low Phytic Acid Network: Some Educated Guesses

Plants ◽  
2019 ◽  
Vol 8 (12) ◽  
pp. 616 ◽  
Author(s):  
Gian Attilio Sacchi ◽  
Fabio Francesco Nocito
Keyword(s):  
Phytic Acid ◽  
Current Knowledge ◽  
Cereal Grains ◽  
Sulfate Transport ◽  
Sulfate Transporter ◽  
Low Phytic Acid ◽  
Transport Regulation ◽  
Transporter Family ◽  
Phosphorus Accumulation ◽  
Group 3

A few new papers report that mutations in some genes belonging to the group 3 of plant sulfate transporter family result in low phytic acid phenotypes, drawing novel strategies and approaches for engineering the low-phytate trait in cereal grains. Here, we shortly review the current knowledge on phosphorus/sulfur interplay and sulfate transport regulation in plants, to critically discuss some hypotheses that could help in unveiling the physiological links between sulfate transport and phosphorus accumulation in seeds.

III. Congenital chloride diarrhea

1999 ◽  
Vol 276 (1) ◽  
pp. G7-G13 ◽  
Author(s):  
Juha Kere ◽  
Hannes Lohi ◽  
Pia Höglund
Keyword(s):  
Gene Family ◽  
Genetic Disease ◽  
Transmembrane Protein ◽  
Founder Effects ◽  
Sulfate Transport ◽  
Sulfate Transporter ◽  
Transporter Family ◽  
Congenital Chloride Diarrhea ◽  
Eukaryotic Species ◽  
The World

Congenital chloride diarrhea (CLD) is a recessively inherited disorder of intestinal electrolyte absorption that involves, specifically, Cl−/[Formula: see text]exchange. CLD is caused by mutations in a chromosome 7 gene, first known as DRA (for downregulated in adenoma). The disease occurs in all parts of the world but is more common in some populations with genetic founder effects. More than 20 mutations in the gene are known to date. The CLD (or DRA) gene encodes a transmembrane protein belonging to the sulfate transporter family with three known members in humans, all associated with a distinct genetic disease. Members of the gene family can transport other anions as well that may turn out to be physiologically more important than sulfate transport. The gene family is well conserved in many prokaryotic and eukaryotic species and is expected to be much larger than presently known.

Impact of cross-breeding on the metabolites of the low phytic acid rice mutant Os-lpa-MH86-1.

2021 ◽  
pp. 433-443
Author(s):  
Chen-guang Zhou ◽  
Yuan-yuan Tan ◽  
Sophia Gossner ◽  
You-fa Li ◽  
Qing-yao Shu ◽  
...  
Keyword(s):  
Phytic Acid ◽  
Seed Viability ◽  
Mutation Breeding ◽  
Cross Breeding ◽  
Low Phytic Acid ◽  
Rice Mutant ◽  
Transporter Family ◽  
Independent Field ◽  
Food And Feed ◽  
The Stability

Abstract Phytic acid (myo-inositol-1,2,3,4,5,6-hexakisphosphate), the major storage form of phosphorus in cereals, is considered as an antinutrient in food and feed. During the past few years, various cereals have been subjected to mutation breeding for generating low phytic acid (lpa) crops. Recently, it was demonstrated that reduction of phytic acid in the rice mutant Os-lpa-MH86-1 obtained by gamma irradiation was due to a disruption of OsSULTR3;3, an orthologue of the sulfate transporter family group 3 genes. The application of a GC/MS-based metabolite profiling approach revealed that the reduction of phytic acid was accompanied by changes in concentrations of metabolites from different classes in the Os-lpa-MH86-1 mutant.Lpa mutant lines often exhibit lower grain yield and seed viability compared with their wild-type parents. To improve the agronomic performance of the Os-lpa-MH86-1 mutant, cross-breeding with a commercial cultivar was performed. The resulting progenies were genotyped using molecular markers to identify homozygous wildtype and lpa mutants from generations F4 to F7. The objectives of this study were: (i) to observe the consistent metabolic changes in Os-lpa-MH86-1 lpa mutants by following their composition over several independent field trials; (ii) to investigate the impact of cross-breeding on the phytic acid content and the metabolic phenotype of the homozygous lpa mutant; and (iii) to assess the stability of the mutation-specific metabolite signature in the lpa progenies over several generations. Statistical assessment of the data via multivariate and univariate approaches demonstrated that the lpa trait and the mutation-induced metabolite signature in the lpa progenies were comparable to the progenitor Os-lpa-MH86-1 mutant and consistently expressed over generations. These findings extend the basis for implementing mutation breeding in the generation of lpa rice cultivars.

Registration of KBNT 1-1 Low Phytic Acid Germplasm of Rice

Crop Science ◽  
2004 ◽  
Vol 44 (1) ◽  
pp. 363 ◽  
Author(s):  
J.N. Rutger ◽  
V. Raboy ◽  
K.A.K. Moldenhauer ◽  
R.J. Bryant ◽  
F.N. Lee ◽  
...  
Keyword(s):  
Phytic Acid ◽  
Low Phytic Acid

scholarly journals Structure and Function of the CFTR Chloride Channel

1999 ◽  
Vol 79 (1) ◽  
pp. S23-S45 ◽  
Author(s):  
DAVID N. SHEPPARD ◽  
MICHAEL J. WELSH
Keyword(s):  
Cystic Fibrosis ◽  
Chloride Channel ◽  
Atp Hydrolysis ◽  
Current Knowledge ◽  
Structure And Function ◽  
Binding Domains ◽  
Transporter Family ◽  
Membrane Spanning ◽  
And Function ◽  
R Domain

Sheppard, David N., and Michael J. Welsh. Structure and Function of the CFTR Chloride Channel. Physiol. Rev. 79 , Suppl.: S23–S45, 1999. — The cystic fibrosis transmembrane conductance regulator (CFTR) is a unique member of the ABC transporter family that forms a novel Cl− channel. It is located predominantly in the apical membrane of epithelia where it mediates transepithelial salt and liquid movement. Dysfunction of CFTR causes the genetic disease cystic fibrosis. The CFTR is composed of five domains: two membrane-spanning domains (MSDs), two nucleotide-binding domains (NBDs), and a regulatory (R) domain. Here we review the structure and function of this unique channel, with a focus on how the various domains contribute to channel function. The MSDs form the channel pore, phosphorylation of the R domain determines channel activity, and ATP hydrolysis by the NBDs controls channel gating. Current knowledge of CFTR structure and function may help us understand better its mechanism of action, its role in electrolyte transport, its dysfunction in cystic fibrosis, and its relationship to other ABC transporters.

scholarly journals Phosphorus application improves grain yield in low phytic acid maize synthetic populations

Heliyon ◽  
2021 ◽  
Vol 7 (9) ◽  
pp. e07912
Author(s):  
Mohammed A.E. Bakhite ◽  
Nkanyiso J. Sithole ◽  
Lembe S. Magwaza ◽  
Alfred O. Odindo ◽  
Shirly T. Magwaza ◽  
...  
Keyword(s):  
Grain Yield ◽  
Phytic Acid ◽  
Low Phytic Acid ◽  
Synthetic Populations ◽  
Phosphorus Application

Milling and Baking Quality of Low Phytic Acid Wheat

Crop Science ◽  
2006 ◽  
Vol 46 (6) ◽  
pp. 2403-2408 ◽  
Author(s):  
M. J. Guttieri ◽  
K. M. Peterson ◽  
E. J. Souza
Keyword(s):  
Phytic Acid ◽  
Low Phytic Acid ◽  
Baking Quality

Pre-calving feeding of rumen-protected rice bran to multiparous dairy cows improves recovery of calcaemia after calving

2016 ◽  
Vol 83 (3) ◽  
pp. 281-288 ◽  
Author(s):  
Javier Martín-Tereso ◽  
Holger Martens ◽  
Carolin Deiner ◽  
Harmen van Laar ◽  
Leo A. den Hartog ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Phytic Acid ◽  
Rice Bran ◽  
Control Diet ◽  
Blood Samples ◽  
Group 3

Dairy cows can have different degrees of hypocalcaemia around calving. Lowering dietary Ca availability before calving can prevent it. Rice bran, treated for lower rumen degradability of phytic acid can reduce dietary availability of Ca. During 3 periods of 3 weeks, 113 multiparous cows calved in a single close-up group, which was fed first a control diet, then 140 g/kg DM of rumen-protected rice bran, and at last the control diet again. Cows joined the group 3 weeks before expected calving date and left it at calving. Blood samples were taken weekly before parturition and 0, 6 and 12 h after calving, as well as 3 and 28 d in lactation. Serum was analysed for Ca, Mg, and P. Rice bran introduction produced a transient serum Ca decrease. Rice bran feeding reduced serum P and its withdrawal reduced serum Mg. Serum Ca at calving, nadir of serum Ca and serum Ca the first 3 d after calving was higher in cows calving during rice bran feeding. Serum P decreased less and recovered faster after calving when cows had been fed rice bran. Rumen-protected rice bran reduced dietary availability of Ca and induced adaptation of Ca metabolism resulting in improved Ca and P homoeostasis at calving.

Preparation of High Bran Arabic Bread with Low Phytic Acid Content

1987 ◽  
Vol 52 (6) ◽  
pp. 1600-1603 ◽  
Author(s):  
S. M. DAGHER ◽  
S. SHADAREVIAN ◽  
W. BIRBARI
Keyword(s):  
Phytic Acid ◽  
Acid Content ◽  
Phytic Acid Content ◽  
Low Phytic Acid
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