scholarly journals Anionic Polymer Brushes for Biomimetic Calcium Phosphate Mineralization—A Surface with Application Potential in Biomaterials

Polymers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1165 ◽  
Author(s):  
Tobias Mai ◽  
Karol Wolski ◽  
Agnieszka Puciul-Malinowska ◽  
Alexey Kopyshev ◽  
Ralph Gräf ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Polymer Brushes ◽  
Polymer Brush ◽  
Inorganic Component ◽  
Hybrid Films ◽  
Anionic Polymer ◽  
Phosphate Mineralization ◽  
Application Potential ◽  
Good Biocompatibility ◽  
Growth Experiments

This article describes the synthesis of anionic polymer brushes and their mineralization with calcium phosphate. The brushes are based on poly(3-sulfopropyl methacrylate potassium salt) providing a highly charged polymer brush surface. Homogeneous brushes with reproducible thicknesses are obtained via surface-initiated atom transfer radical polymerization. Mineralization with doubly concentrated simulated body fluid yields polymer/inorganic hybrid films containing AB-Type carbonated hydroxyapatite (CHAP), a material resembling the inorganic component of bone. Moreover, growth experiments using Dictyostelium discoideum amoebae demonstrate that the mineral-free and the mineral-containing polymer brushes have a good biocompatibility suggesting their use as biocompatible surfaces in implantology or related fields.

Polymer Brush Controlled Bioinspired Calcium Phosphate Mineralization and Bone Cell Growth

2011 ◽  
Vol 12 (10) ◽  
pp. 3753-3760 ◽  
Author(s):  
Ruben Löbbicke ◽  
Munish Chanana ◽  
Helmut Schlaad ◽  
Christine Pilz-Allen ◽  
Christina Günter ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Cell Growth ◽  
Polymer Brush ◽  
Bone Cell ◽  
Phosphate Mineralization

scholarly journals Quick extracellular biosynthesis of low-cadmium ZnxCd1−xS quantum dots with full-visible-region tuneable high fluorescence and its application potential assessment in cell imaging

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21813-21823
Author(s):  
Shiyue Qi ◽  
Ji Chen ◽  
Xianwei Bai ◽  
Yahui Miao ◽  
Shuhui Yang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Energy Saving ◽  
Metal Nanoparticles ◽  
Cell Imaging ◽  
Visible Region ◽  
Extracellular Biosynthesis ◽  
Application Potential ◽  
Good Biocompatibility ◽  
High Fluorescence ◽  
Environmentally Sound

The biosynthesis of metal nanoparticles/QDs has been universally recognized as environmentally sound and energy-saving, generating less pollution and having good biocompatibility, which is most needed in biological and medical fields.

scholarly journals Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization

2017 ◽  
Vol 8 ◽  
pp. 772-783 ◽  
Author(s):  
Mohamed Hamed Misbah ◽  
Mercedes Santos ◽  
Luis Quintanilla ◽  
Christina Günter ◽  
Matilde Alonso ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Click Chemistry ◽  
Recombinant Dna ◽  
Fibrillar Structure ◽  
Cross Link ◽  
Recombinant Dna Technology ◽  
Peptide Epitope ◽  
Phosphate Mineralization ◽  
Potential Applications ◽  
Dna Technology

Understanding the mechanisms responsible for generating different phases and morphologies of calcium phosphate by elastin-like recombinamers is supreme for bioengineering of advanced multifunctional materials. The generation of such multifunctional hybrid materials depends on the properties of their counterparts and the way in which they are assembled. The success of this assembly depends on the different approaches used, such as recombinant DNA technology and click chemistry. In the present work, an elastin-like recombinamer bearing lysine amino acids distributed along the recombinamer chain has been cross-linked via Huisgen [2 + 3] cycloaddition. The recombinamer contains the SNA15 peptide domains inspired by salivary statherin, a peptide epitope known to specifically bind to and nucleate calcium phosphate. The benefit of using click chemistry is that the hybrid elastin-like-statherin recombinamers cross-link without losing their fibrillar structure. Mineralization of the resulting hybrid elastin-like-statherin recombinamer hydrogels with calcium phosphate is described. Thus, two different hydroxyapatite morphologies (cauliflower- and plate-like) have been formed. Overall, this study shows that crosslinking elastin-like recombinamers leads to interesting matrix materials for the generation of calcium phosphate composites with potential applications as biomaterials.

scholarly journals Understanding the early stages of calcium phosphate mineralization through hyperpolarized NMR techniques.

2021 ◽  
Author(s):  
Tristan Georges ◽  
Ludovica Epasto ◽  
Albina Selimović ◽  
Dennis Kurzbach ◽  
Thierry Azaïs
Keyword(s):  
Calcium Phosphate ◽  
Early Stages ◽  
Phosphate Mineralization ◽  
Nmr Techniques

Polymer Brushes: High-Resolution, Large-Area, Serial Fabrication of 3D Polymer Brush Structures by Parallel Dip-Pen Nanodisplacement Lithography (Small 23/2012)

Small ◽  
2012 ◽  
Vol 8 (23) ◽  
pp. 3567-3567 ◽  
Author(s):  
Xuechang Zhou ◽  
Zhilu Liu ◽  
Zhuang Xie ◽  
Xuqing Liu ◽  
Zijian Zheng
Keyword(s):  
High Resolution ◽  
Polymer Brushes ◽  
Polymer Brush ◽  
Large Area

scholarly journals Theory of Lubrication due to Poly-Electrolyte Polymer Brushes

2007 ◽  
Vol 1049 ◽  
Author(s):  
Jeffrey B. Sokoloff
Keyword(s):  
Field Theory ◽  
Osmotic Pressure ◽  
Dry Friction ◽  
Polymer Brushes ◽  
Mean Field Theory ◽  
Polymer Brush ◽  
Mean Field ◽  
The Mean ◽  
Coated Surfaces

AbstractIt is shown using a method based on the mean field theory of Miklavic Marcelja that it should be possible for osmotic pressure due to the counterions associated with the two polyelectrolyte polymer brush coated surfaces to support a reasonable load (i.e., about 105 Pa) with the brushes held sufficiently far apart to prevent entanglement of polymers belonging to the two brushes, thus avoiding what is likely to be the dominant mechanisms for static and dry friction.

The structure of polymer brushes near the transition from dilute to dense systems. A computer simulation study

Soft Matter ◽  
2021 ◽  
Author(s):  
Piotr Polanowski ◽  
Andrzej Sikorski
Keyword(s):  
Computer Simulation ◽  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Simulation Study ◽  
Polymer Brushes ◽  
Polymer Brush ◽  
Coarse Grained ◽  
Computer Simulation Study ◽  
Coarse Grained Model ◽  
Cooperative Motion

Monodisperse polymer brushes were studied by means of Monte Carlo simulations. A coarse-grained model of a polymer brush was designed in order and the Cooperative Motion Algorithm was employed to...

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