scholarly journals Near-Field Electrospinning and Melt Electrowriting of Biomedical Polymers—Progress and Limitations

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1097
Author(s):  
William E. King ◽  
Gary L. Bowlin

Near-field electrospinning (NFES) and melt electrowriting (MEW) are the process of extruding a fiber due to the force exerted by an electric field and collecting the fiber before bending instabilities occur. When paired with precise relative motion between the polymer source and the collector, a fiber can be directly written as dictated by preprogrammed geometry. As a result, this precise fiber control results in another dimension of scaffold tailorability for biomedical applications. In this review, biomedically relevant polymers that to date have manufactured fibers by NFES/MEW are explored and the present limitations in direct fiber writing of standardization in published setup details, fiber write throughput, and increased ease in the creation of complex scaffold geometries are discussed.


Polymers ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 1
Author(s):  
William E. King ◽  
Yvonne Gillespie ◽  
Keaton Gilbert ◽  
Gary L. Bowlin

Electrospinning is a popular method for creating random, non-woven fibrous templates for biomedical applications, and a subtype technique termed near-field electrospinning (NFES) was devised by reducing the air gap distance to millimeters. This decreased working distance paired with precise translational motion between the fiber source and collector allows for the direct writing of fibers. We demonstrate a near-field electrospinning device designed from a MakerFarm Prusa i3v three-dimensional (3D) printer to write polydioxanone (PDO) microfibers. PDO fiber diameters were characterized over the processing parameters: Air gap, polymer concentration, translational velocity, needle gauge, and applied voltage. Fiber crystallinity and individual fiber uniformity were evaluated for the polymer concentration and translational fiber deposition velocity. Fiber stacking was evaluated for the creation of 3D templates to guide the alignment of human gingival fibroblasts. The fiber diameters correlated positively with polymer concentration, applied voltage, and needle gauge; and inversely correlated with translational velocity and air gap distance. Individual fiber diameter variability decreases, and crystallinity increases with increasing translational fiber deposition velocity. These data resulted in the creation of tailored PDO 3D templates, which guided the alignment of primary human fibroblast cells. Together, these results suggest that NFES of PDO can be scaled to create precise geometries with tailored fiber diameters for biomedical applications.



Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 924
Author(s):  
Alexander B. Shcherbakov ◽  
Vladimir V. Reukov ◽  
Alexander V. Yakimansky ◽  
Elena L. Krasnopeeva ◽  
Olga S. Ivanova ◽  
...  

The development of advanced composite biomaterials combining the versatility and biodegradability of polymers and the unique characteristics of metal oxide nanoparticles unveils new horizons in emerging biomedical applications, including tissue regeneration, drug delivery and gene therapy, theranostics and medical imaging. Nanocrystalline cerium(IV) oxide, or nanoceria, stands out from a crowd of other metal oxides as being a truly unique material, showing great potential in biomedicine due to its low systemic toxicity and numerous beneficial effects on living systems. The combination of nanoceria with new generations of biomedical polymers, such as PolyHEMA (poly(2-hydroxyethyl methacrylate)-based hydrogels, electrospun nanofibrous polycaprolactone or natural-based chitosan or cellulose, helps to expand the prospective area of applications by facilitating their bioavailability and averting potential negative effects. This review describes recent advances in biomedical polymeric material practices, highlights up-to-the-minute cerium oxide nanoparticle applications, as well as polymer-nanoceria composites, and aims to address the question: how can nanoceria enhance the biomedical potential of modern polymeric materials?



Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 703
Author(s):  
Sung-Gu Kang ◽  
Min-Su Song ◽  
Joon-Woo Kim ◽  
Jung Woo Lee ◽  
Jeonghyun Kim

Near-field communication (NFC) is a low-power wireless communication technology used in contemporary daily life. This technology contributes not only to user identification and payment methods, but also to various biomedical fields such as healthcare and disease monitoring. This paper focuses on biomedical applications among the diverse applications of NFC. It addresses the benefits of combining traditional and new sensors (temperature, pressure, electrophysiology, blood flow, sweat, etc.) with NFC technology. Specifically, this report describes how NFC technology, which is simply applied in everyday life, can be combined with sensors to present vision and opportunities to modern people.



2020 ◽  
Vol 9 (5) ◽  
pp. 305-312
Author(s):  
Ryan Cardman ◽  
Luís F. Gonçalves ◽  
Rachel E. Sapiro ◽  
Georg Raithel ◽  
David A. Anderson

AbstractWe present electric field measurements and imaging of a Yagi–Uda antenna near-field using a Rydberg atom–based radio frequency electric field measurement instrument. The instrument uses electromagnetically induced transparency with Rydberg states of cesium atoms in a room-temperature vapor and off-resonant RF-field–induced Rydberg-level shifts for optical SI-traceable measurements of RF electric fields over a wide amplitude and frequency range. The electric field along the antenna boresight is measured using the atomic probe at a spatial resolution of ${\lambda }_{RF}/2$ with electric field measurement uncertainties below 5.5%, an improvement to RF measurement uncertainties provided by existing antenna standards.



10.14311/1033 ◽  
2008 ◽  
Vol 48 (4) ◽  
Author(s):  
Y. Klenko ◽  
V. Scholtz

Point-to-plane corona discharge is widely used for modifying polymer surfaces for biomedical applications and for sterilization and decontamination. This paper focuses on an experimental investigation of the influence of the single-point and multi-point corona discharge electric field on gel surface. Three types of gelatinous agar were used as the gel medium: blood agar, nutrient agar and Endo agar. The gel surface modification was studied for various time periods and discharge currents. 



RSC Advances ◽  
2018 ◽  
Vol 8 (40) ◽  
pp. 22286-22292
Author(s):  
Anqi Yu

Enhancing the localized electric field of graphene plasmons with a metallic split-mesh structure by more than an order of magnitude.



2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Junji Nozaki ◽  
Musashi Fukumura ◽  
Takaaki Aoki ◽  
Yutaka Maniwa ◽  
Yohei Yomogida ◽  
...  


2018 ◽  
Vol 10 (14) ◽  
pp. 11529-11538 ◽  
Author(s):  
Qiang Chen ◽  
Jiajia Jing ◽  
Hongfei Qi ◽  
Ifty Ahmed ◽  
Haiou Yang ◽  
...  


2021 ◽  
pp. 1-1
Author(s):  
Zachary D. Drummond ◽  
Kevin E. Claytor ◽  
Ross N. Adelman ◽  
David R. Allee ◽  
David M. Hull


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