scholarly journals Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives

Polymers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1590
Author(s):  
Qiannan Sun ◽  
Lingyun Zhang ◽  
Rushui Bai ◽  
Zimeng Zhuang ◽  
Yunfan Zhang ◽  
...  

Repairing tooth defects with dental resin composites is currently the most commonly used method due to their tooth-colored esthetics and photocuring properties. However, the higher than desirable failure rate and moderate service life are the biggest challenges the composites currently face. Secondary caries is one of the most common reasons leading to repair failure. Therefore, many attempts have been carried out on the development of a new generation of antimicrobial and therapeutic dental polymer composite materials to inhibit dental caries and prolong the lifespan of restorations. These new antimicrobial materials can inhibit the formation of biofilms, reduce acid production from bacteria and the occurrence of secondary caries. These results are encouraging and open the doors to future clinical studies on the therapeutic value of antimicrobial dental resin-based restoratives. However, antimicrobial resins still face challenges such as biocompatibility, drug resistance and uncontrolled release of antimicrobial agents. In the future, we should focus on the development of more efficient, durable and smart antimicrobial dental resins. This article focuses on the most recent 5 years of research, reviews the current antimicrobial strategies of composite resins, and introduces representative antimicrobial agents and their antimicrobial mechanisms.

Author(s):  
Anabela Baptista Paula ◽  
Debbie Toste ◽  
Alfredo Marinho ◽  
Inês Amaro ◽  
Carlos-Miguel Marto ◽  
...  

(1) Background: Bisphenol A (BPA) based dental resins are commonly used in preventive and reparative dentistry. Since some monomers may remain unpolymerized in the application of dental resin, they dissolve in the saliva. (2) Methods: The literature search was carried out in Pubmed, Cochrane and Embase databases. Randomized controlled trials, cohort studies and case-control studies that evaluated BPA levels in human urine, saliva and/or blood were included. (3) Results: The initial search had 5111 results. A total of 20 studies were included in the systematic review. Most studies showed an increase of the levels of bisphenol A 1 h after treatments with composite resins and dental sealants. One week after treatments the levels were decreased. (4) Conclusions: Some clinical precautions should be taken to decrease the release of BPA, namely the use of rubber dam, the immediate polishing of all resins used, or the use of glycerin gel to avoid non-polymerization of the last resin layer, and mouthwash after treatment. Another preventive measure in addition to the above-mentioned is the use of the smallest possible number of restorations or sealants, a maximum of four per appointment. These measures are even more important in children, adolescents and pregnant women.


2021 ◽  
Author(s):  
Dan-Lei Yang ◽  
Ya-Nan Cui ◽  
Qian Sun ◽  
Mei Liu ◽  
Hao Niu ◽  
...  

The accumulation of bacteria at the margin of dental resin composites is the main reason of secondary caries, which may further cause failure of prosthodontics. Therefore, antibacterial activity is highly...


2019 ◽  
Vol 8 (8) ◽  
Author(s):  
Luiz Henrique Soares Torres ◽  
Luiza Monzoli Covre ◽  
Caio Pimenteira Uchôa ◽  
Déborah Laurindo Pereira Santos ◽  
Renato Torres Augusto Neto ◽  
...  

As resinas compostas fotopolimerizáveis têm tido cada vez mais indicações na odontologia restauradora devido às vantagens que apresentam. Porém variações na técnica de fotoativação, densidade de energia, intensidade da luz e tempo de irradiação podem gerar polimerização incompleta, o que pode resultar em uma resina composta com alta porosidade, pouca dureza, baixo polimento, alta capacidade de pigmentação ou efeitos tóxicos na polpa. Este estudo tem por objetivo analisar o efeito do tempo de polimerização na pigmentação extrínseca de três resinas compostas fotopolimerizáveis. Utilizando uma fonte de LED, foram confeccionados 180 espécimes de resina composta microhíbrida, nanohíbrida e nanoparticulada, com diferentes protocolos de polimerização. Os espécimes foram subdivididos em grupos de acordo com o agente pigmentante. Com o uso de um colorímetro, foram analisados quanto à mudança de cor (ΔE). Os dados foram submetidos ao teste ANOVA e Duncan (α=0,05). A resina composta microhíbrida apresentou os menores valores de ΔE em comparação à nanoparticulada e à nanohíbrida quando imersos em vinho. Quanto maior o tempo de polimerização menores valores de ΔE foram obtidos. Não somente o tempo de polimerização influencia no grau de pigmentação, mas também fatores intrínsecos às resinas compostas tais como carga, agente fotoiniciador e matriz orgânica.Descritores: Autocura de Resinas Dentárias; Materiais Dentários; Pigmentação.ReferênciasMatson MR, Matson AMFP. Avaliação do grau de conversão de resinas compostas quando ativadas por luz halógena: método convencional, alta potência e método “soft”. Rev Inst Ciênc Saúde. 2006;24(4):307-11.Delaviz Y, Finer Y, Santerre JP. Biodegradation of resin composites and adhesivesby oral bacteria and saliva: A rationale for new material designs that consider the clinical environment and treatment challenges. Dent Mater. 2014;30(1):16-32.Nahsan FPS, Ueda JK, Silva JO, Schimitt VL, Naufel FS, Formighieri LA et al. Estabilidade de cor de resina composta após imersão em café, água e solução de clorexidina. Rev Bras Pesq Saúde. 2009;11(2):13-7.Al  Kheraif  AA,  Qasim  SS,  Ramakrishnaiah  R,  Rehman  I.  Effect  of different beverages on the color stability and degree of conversion of nano and microhybrid composites. Dent Mater J. 2013;(32)2:326-31.Ceballos L, Fuentes MV, Tafalla H, Martínez A, Flores J, Rodríguez J. Curing effectiveness of resin composites at different exposure times using LED and halogen units. Med Oral Pathol Oral Cir Bucal 2009;14(1):e51-6.Rahiotis C, Patsouri K, Silikas N, Kakaboura A. Curing efficiency of high- intensity light-emitting diode (LED) devices. J Oral Sci.  2010; 52(2):187-95.Sgarbi SC, Pereira SK, Martins JMH, Oliveira MAC, Mazur RF. Degree of conversion of resin composites light activated by halogen light and led analyzed by ultraviolet spectrometry. Rev Clín Pesq Odontol. 2010;6(3):223-30.Caldarelli PG, Beltrani FC, Santos FA, Shibayama R, Hoepper  MG. Manchamento de uma resina composta e sua Relação com o efeito da intensidade da luz Emitida por aparelhos fotopolimerizadores de Lâmpada halôgena. Rev Fac Odontol Aracatuba. 2011;(32)2:44-8.Valentini F, Oliveira SGD, Guimarães GZ, Barbosa RPS, Moraes RR. Effect of surface sealant on the color stability of composite resin restorations. Braz Dent J. 2011;22(5):365-68.Freitas ABDA, Gomes HR, Guimarães FBR, Marinho VA, Barros LM. Influência do tipo de aparelho fotopolimerizador na absorção de água por restaurações de resina composta. Rev Inst Ciênc Saúde.  2008;(26)1:65-9.Porto ICCM, Soares LES, Martin AA, Cavalli V, Liporoni PCS. Influence of the photoinitiator system and light photoactivation units on the degree of conversion  of  dental  composites. Braz Oral Res. 2010;24(4):475-81.Pequeno JHP, Araújo GS, Neri JR, Bomfim AGM, Mendonça JS, Santiago SL. Efeito dos protocolos de fotoativação na dureza de uma resina composta nanoparticulada. ROBRAC. 2012;21(56):394-97.Uhl A, Mills RW, Rzanny AE, Jandt KD. Time dependence of composite shrinkage using halogen and LED light curing. Dent Mater. 2005;21(3):278-86.Eick JD, Kotha SP, Chappelow CC, Kilway KV, Giese GJ, Glaros AG et al. Properties of  silorane-based  dental resins and composites containing    a    stressreducing  monomer. Dent Mater. 2007;23(8):1011-17.Neumann MG, Schmitt CC, Ferreira GC, Correa IC. The initiating radical yields and the efficiency of polymerization for various dental photoinitiators excited by different lightcuring units. Dent Mater. 2006;22(6):576-84.Asmussen   E,  Peutzfeldt   A.   Influence   of   composition   on   rate   of polymerization contraction of light-curing resin composites. Acta Odontol Scand. 2002;60(3):146-50.Silva EH, Albuquerque RC, Lanza LD, Vieira GC, Peixoto RT, Alvim HH et al. Influence of different light sources on the conversion of composite resins. Indian J Dent Res. 2011;22(6):790-94.Souza E, Espíndola M, Diegoli NM, Kuroshima KN. Avaliação da alteração de cor de diferentes compósitos restauradores - influência de corantes usados na cavidade oral - estudo in vitro. RGO. 2006;54(1):43-6.Salvego RN, Dias RPB. Figueiredo JLG. Estabilidade de cor de resinas compostas no processo de manchamento e clareamento, Rev Dental Press Estét. 2013;10(3):54-62.Firoozmandi LM, Balducci I, Araújo MAM.  Influência da Fotopolimerização e da Cor da Resina Composta na Microdureza. Pesq Bras Odontoped Clín Integr. 2009;9(1):37-42.Anfe TEA, Agra CM, Vieira GF. Comparação de duas técnicas de fotoativação na sorção e solubilidade de resinas compostas em solução de etanol. J Biodent Biomater. 2011;1(1):61-7.Villalta P, Lu H, Okte Z, Garcia-Godoy F, Powers JM. Effects of staining and bleaching on color change of dental composite resins. J Prosthet Dent. 2006;95(2):137-42.Barghi N, Berry T, Hatton C. Evaluation intensity output of curing lights in private dental offices. J. am. dent. assoc. 1994;125(7):992-96.Santini A, Miletic V, Swift MD, Bradley M. Degree of conversion and microhardness of TPO-containing resin-based composites cured by polywave and monowave LED units. J Dent. 2012;40(7):577-84.


2009 ◽  
Vol 39 (4) ◽  
pp. 961-968 ◽  
Author(s):  
Débora da Costa e Silva ◽  
Sanmya Beatriz da Silva Pereira Tiradentes ◽  
Rosana Cristina Pereira Parente ◽  
Maria Fulgência Costa Lima Bandeira

The purpose of this study is to evaluate in vitro the color stability of composite resins when exposed to beverages with high coloring contents from the Amazon region. 240 samples from four different composite brands (Natural Look, Z350, 4Seasons and Opallis) of hue A3 were fabricated using an acrylic matrix. The samples were stored in distilled water at 37ºC for 24 hours. The initial color (T0) was registered using a Canon EOS Rebel XTi 10 mp camera, and then the samples were divided into four groups (n=15): G1 (coffee), G2 (açaí juice), G3 (energetic guaraná) and G4 (control - distilled water). The samples were exposed to solutions of DES (6hs) and RE (18hs) and placed in a double boiler under constant agitation, at 37ºC for 30 days. The samples were immersed in the coloring solutions for 15 minutes daily. After 7, 15 and 30 days, new photographic registers were made (T1, T2 and T3). The images were analyzed using Corel PHOTO-PAINT 12 software to identify the colors through the HSB system. The Kruskal-Wallis and t tests (p<0.05) demonstrated significant differences in color (hue, saturation and brightness). The results revealed that none of the tested composites showed color stability when exposed to coloring solutions, and that the Amazon region beverages (açaí juice and energetic guaraná) showed to be less coloring than coffee.


e-Polymers ◽  
2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Jean Baptiste Robin ◽  
Jean Cédric Durand ◽  
Loic Derely ◽  
Bruno Jacquot ◽  
Frédéric Cuisinier ◽  
...  

AbstractThis study investigated degrees of conversion of oxygen inhibited layer (OIL) of organic dental resins for restoration using Confocal-Raman spectroscopy. The aim was to determine which laser is adapted to determine the degrees of conversion of OIL and to measure variations of thickness and degrees of conversion in OIL with respect to monomers proportions. Bis-GMA (bis-phenol A glycidyl dimethacrylate) and TEGDMA (triethylene glycol dimethacrylate) based resins with various ratio of an equimolecular mixture of camphorquinone/EDMAB (ethyl (4-dimethyl amino) benzoate) were studied with different lasers by confocal- Raman spectroscopy. Results show that this technique is adapted for the non destructive measurement of OIL. The Thickness of OIL is not correlated with the proportions of Bis-GMA and TEGDMA in the resin and was close to 3-4μm. Thickness of OIL is very thin without inorganic fillers (3 or 4 μm). Inorganic fillers might be responsible of greater OIL in composite resins.


Polymers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 601 ◽  
Author(s):  
J. J. Encalada-Alayola ◽  
Y. Veranes-Pantoja ◽  
J. A. Uribe-Calderón ◽  
J. V. Cauich-Rodríguez ◽  
J. M. Cervantes-Uc

Bis-GMA/TTEGDMA-based resin composites were prepared with two different types of nanoclays: an organically modified laminar clay (Cloisite® 30B, montmorillonite, MMT) and a microfibrous clay (palygorskite, PLG). Their physicochemical and mechanical properties were then determined. Both MMT and PLG nanoclays were added into monomer mixture (1:1 ratio) at different loading levels (0, 2, 4, 6, 8 and 10 wt.%), and the resulting composites were characterized by scanning electron microscopy (SEM), thermogravimetric analysis (TGA), dynamic mechanical analysis (DMA) and mechanical testing (bending and compressive properties). Thermal properties, depth of cure and water absorption were not greatly affected by the type of nanoclay, while the mechanical properties of dental resin composites depended on both the variety and concentration of nanoclay. In this regard, composites containing MMT displayed higher mechanical strength (both flexural and compression) than those resins prepared with PLG due to a poor nanoclay dispersion as revealed by SEM. Solubility of the composites was dependent not only on nanoclay-type but also the mineral concentration. Dental composites fulfilled the minimum depth cure and solubility criteria set by the ISO 4049 standard. In contrast, the minimum bending strength (50 MPa) established by the international standard was only satisfied by the dental resins containing MMT. Based on these results, composites containing either MMT or PLG (at low filler contents) are potentially suitable for use in dental restorative resins, although those prepared with MMT displayed better results.


2019 ◽  
Vol 64 (11) ◽  
pp. 1007-1014
Author(s):  
Tong XU ◽  
◽  
Jia-Hui ZHANG ◽  
Zhao-Ying LIU ◽  
Xuan LI ◽  
...  

2021 ◽  
Vol 37 (3) ◽  
pp. 413-422
Author(s):  
Nikolaos Loumprinis ◽  
Eva Maier ◽  
Renan Belli ◽  
Anselm Petschelt ◽  
George Eliades ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 2769
Author(s):  
Jonne Oja ◽  
Lippo Lassila ◽  
Pekka K. Vallittu ◽  
Sufyan Garoushi

The aim of current in vitro research was to determine the effect of hydrothermal accelerated aging on the mechanical properties and wear of different commercial dental resin composites (RCs). In addition, the effect of expiration date of the composite prior its use was also evaluated. Five commercially available RCs were studied: Conventional RCs (Filtek Supreme XTE, G-aenial Posterior, Denfil, and >3y expired Supreme XTE), bulk-fill RC (Filtek Bulk Fill), and short fiber-reinforced RC (everX Posterior). Three-point flexural test was used for determination of ultimate flexural strength (n = 8). A vickers indenter was used for testing surface microhardness. A wear test was conducted with 15,000 chewing cycles using a dual-axis chewing simulator. Wear pattern was analyzed by a three-dimensional (3D) noncontact optical profilometer. Degree of C=C bond conversion of monomers was determined by FTIR-spectrometry. The specimens were either dry stored for 48 h (37 °C) or boiled (100 °C) for 16 h before testing. Scanning electron microscopy (SEM) was used to evaluate the microstructure of each material. Data were analyzed using ANOVA (p = 0.05). Hydrothermal aging had no significant effects on the surface wear and microhardness of tested RCs (p > 0.05). While flexural strength significantly decreased after aging (p < 0.05), except for G-aenial Posterior, which showed no differences. The lowest average wear depth was found for Filtek Bulk Fill (29 µm) (p < 0.05), while everX Posterior and Denfil showed the highest wear depth values (40, 39 µm) in both conditions. Passing the expiration date for 40 months did not affect the flexural strength and wear of tested RC. SEM demonstrated a significant number of small pits on Denfil’s surface after aging. It was concluded that the effect of accelerated aging may have caused certain weakening of the RC of some brands, whereas no effect was found with one brand of RC. Thus, the accelerated aging appeared to be more dependent on material and tested material property.


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