scholarly journals Bubble Formation in Droplet Dosing Devices for Liquid Medicine

Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 747
Author(s):  
Sebastian Hummel ◽  
Michael Haub ◽  
Martin Bogner ◽  
Hermann Sandmaier

Droplet dosing devices for liquid medicine are widely spread in self-medication for prevention or in the event of illness. This paper presents investigations on the often unnoticed process of bubble formation in droplet dosing devices for liquid medicine which is decisive for the whole functionality of these systems. To obtain information about this process and how it affects the dosage, drip operations with an exemplary device have been evaluated. Based on these evaluations the bubble formation is explained qualitatively. Finally a mathematical approach to predict critical changes in the bubble formation process is presented.

Author(s):  
Zhengzheng Zhang ◽  
Liangxing Li ◽  
Shuanglei Zhang ◽  
Afnan Saleem

Abstract A visualized experimental system is designed and constructed to investigate the bubble dynamic in a flowing liquid layer. Motivated by reducing uncertainties and digging a deep understand on the formation mechanism of boiling bubbles, the bubbles are formed by injecting air through a submerged orifice in our present work, where the influence of thermal physics, nucleation site density and dry spot are stripped. The water flow rate and the air flow rate are in the range of 72–324 ml/min and 0.8–2.0 ml/min, respectively. The bubble formation process in the smooth channel and the rib channel are investigated. The results state that increasing the liquid flow rates lead to the increasing bubble detachment frequency and the decreasing bubble detachment volume. Besides, the larger the liquid flow rate is, the closer the bubble center of mass is to the wall. The rib has a significant influence on the bubble formation process. In the rib channel, it is more difficult for bubbles to detach from the orifice compared that in a smooth channel. Besides, the bubble detachment volume in a rib channel is larger than it in a smooth channel.


2016 ◽  
Vol 61 ◽  
pp. 599-609 ◽  
Author(s):  
M.H. Jobehdar ◽  
K. Siddiqui ◽  
A.H. Gadallah ◽  
W.A. Chishty

2011 ◽  
Vol 37 (9) ◽  
pp. 1059-1071 ◽  
Author(s):  
Mitsuhiro Ohta ◽  
Daisuke Kikuchi ◽  
Yutaka Yoshida ◽  
Mark Sussman

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Ruitong Xiong ◽  
Zhengyi Zhang ◽  
Jianxin Shen ◽  
Yafu Lin ◽  
Yong Huang ◽  
...  

Laser direct writing, a noncontact modified laser-induced forward transfer (LIFT) technique, has emerged as a promising technology for various applications from microelectronics printing to biofabrication. For it to be a viable technology, the bubble formation process during laser direct writing should be carefully examined. In this study, the bubble formation process during the laser direct writing of glycerol–water solutions has been studied using a nucleation-based phase explosion modeling approach. The effects of laser fluence and material properties of glycerol solution on the resulting bubble geometry have been examined both analytically and experimentally. Overall, a satisfactory modeling accuracy has been achieved, while the proposed modeling approach slightly underestimates the bubble diameter. Both the measured and predicted bubble diameters increase when the laser fluence increases. Interestingly, the measured and predicted diameters first decrease, then increase, and decrease again with the increase of glycerol concentration. Furthermore, it is noted that the bubble diameter is more sensitive to the laser fluence than the glycerol concentration.


2020 ◽  
Vol 117 ◽  
pp. 110144 ◽  
Author(s):  
Zhengzheng Zhang ◽  
Liangxing Li ◽  
Wei Xie ◽  
Huasheng Wang

Sensors ◽  
2020 ◽  
Vol 20 (15) ◽  
pp. 4219
Author(s):  
Jose R. Guzman-Sepulveda ◽  
Daniel A. May-Arrioja ◽  
Miguel A. Fuentes-Fuentes ◽  
Natanael Cuando-Espitia ◽  
Miguel Torres-Cisneros ◽  
...  

An all-fiber approach is presented to measure surface tension. The experimental realization relies on the use of a specialty fiber, a so-called two-hole fiber (THF), which serves a two-fold purpose: providing a capillary channel to produce bubbles while having the means to measure the power reflected at the end facet of the fiber core. We demonstrate that provided a controlled injection of gas into the hollow channels of the THF, surface tension measurements are possible by simply tracking the Fresnel reflection at the distal end of the THF. Our results show that the characteristic times involved in the bubble formation process, from where the surface tension of the liquids under test is retrieved, can be measured from the train of pulses generated by the continuous formation and detachment of bubbles.


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