scholarly journals Scorpion Envenomation of Lactating Rats Decreases the Seizure Threshold in Offspring

Toxins ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 853
Author(s):  
Marina de Oliveira Rodrigues Barbosa ◽  
Maria Eliza F. do Val de Paulo ◽  
Ana Leonor Abrahão Nencioni
Keyword(s):  
Perinatal Period ◽  
Postnatal Period ◽  
Seizure Threshold ◽  
Long Term Effects ◽  
Crude Venom ◽  
Long Time ◽  
Few Data ◽  
The Relationship ◽  
Convulsive Threshold

Few data are available in the literature describing the long-term effects of envenoming in the perinatal period. In this study, the relationship between envenoming of lactating rats and possible behavioral changes in the mother and in her offspring were investigated. Lactating Wistar rats received a single dose of T. serrulatus crude venom on postnatal days 2 (V2), 10 (V10) or 16 (V16), and had their maternal behavior evaluated. The seizure threshold was evaluated in adulthood offspring. A decrease in maternal care during envenoming was observed in V2 and V10 groups. The retrieval behavior was absent in the V2 group, and a lower seizure threshold in the adult offspring of all groups was observed. During envenoming, mothers stayed away from their offspring for a relatively long time. Maternal deprivation during the early postnatal period is one of the most potent stressors for pups and could be responsible, at least in part, for the decrease in the convulsive threshold of the offspring since stress is pointed to as a risk factor for epileptogenesis. Furthermore, the scorpionic accident generates an intense immune response, and inflammation in neonates increases the susceptibility to seizures in adulthood. Therefore, maternal envenoming during lactation can have adverse effects on offspring in adulthood.

The Relationship Between Adverse Childhood Experiences and Recidivism in a Sample of Juvenile Offenders in Community-Based Treatment

2015 ◽  
Vol 61 (11) ◽  
pp. 1210-1242 ◽  
Author(s):  
Kevin T. Wolff ◽  
Michael T. Baglivio ◽  
Alex R. Piquero
Keyword(s):  
Juvenile Offenders ◽  
Adverse Childhood Experiences ◽  
Life Outcomes ◽  
Long Term Effects ◽  
Community Based ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Juvenile Justice Policy ◽  
The Relationship

Adverse childhood experiences (ACEs) have been identified as a key risk factor for a range of negative life outcomes, including delinquency. Much less is known about how exposure to negative experiences relates to continued offending among juvenile offenders. In this study, we examine the effect of ACEs on recidivism in a large sample of previously referred youth from the State of Florida who were followed for 1 year after participation in community-based treatment. Results from a series of Cox hazard models suggest that ACEs increase the risk of subsequent arrest, with a higher prevalence of ACEs leading to a shorter time to recidivism. The relationship between ACEs and recidivism held quite well in demographic-specific analyses. Implications for empirical research on the long-term effects of traumatic childhood events and juvenile justice policy are discussed.

The importance of superior-quality wildlife habitats

2004 ◽  
Vol 80 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Ian D Thompson
Keyword(s):  
Habitat Selection ◽  
Habitat Quality ◽  
Population Level ◽  
Individual Fitness ◽  
Animal Populations ◽  
Cumulative Change ◽  
Few Data ◽  
Managed Landscapes ◽  
The Relationship

While animals may use many habitat types, relatively few are preferred and fewer yet are superior in quality (referring to individual fitness as the measure of quality). Historical reduction in habitat quality for some wildlife species has occurred such that we may now have limited reference to original superior-quality habitats. As time passes, managers may be unaware that superior habitats are slowly disappearing and that the slow but cumulative change is significant to a species at the population level. The perception of superior-quality habitat also changes with each successive generation of managers based on their experiences. This paper raises the concern that retrospective work may often be required to determine past forest habitats and associated animal populations to avoid the risk of falling into a trap of not recognizing ever-declining habitat quality through time and relegating animals to what is in fact much poorer quality habitat than those to which they are actually best adapted. Further, the relationship between relative abundance and habitat quality may often be uncertain owing to maladaptive habitat selection by animals, inappropriate survey timing or interannual population differences. While we have begun to appreciate aspects of habitat selection for many forest species, few data are yet available that relate selected habitats to fitness of individual animals. Hence, while we may have models to predict habitat use, considerable research remains to be done to be able to predict long-term sustainability of species in managed landscapes. Key words: habitat quality, forest management, sustainability, biodiversity

Early Post-Partum Contact and Later Attitudes

1980 ◽  
Vol 3 (3) ◽  
pp. 273-286 ◽  
Author(s):  
Peter de Chateau
Keyword(s):  
Post Partum ◽  
Postnatal Period ◽  
Child Rearing ◽  
Control Group ◽  
Maternal Behaviour ◽  
Relative Importance ◽  
Long Term Effects ◽  
Infant Behaviour

In a randomized, prospective study the long-term effects of early post-partum skin-toskin and suckling contact was studied. In follow-up studies 36 hours, 3 and 12 months after delivery maternal behaviour, infant behaviour, the duration of breast feeding and certain attitudes towards child rearing procedures were shown to develop differently in a group of mothers and infants with early post-natal contacts as compared to a control group. Three years after delivery parents with early contact appreciated their children's language development to be faster; the number of siblings born in these families was greater than in controls. In the discussion, the relative importance of the immediate postnatal period is emphasized, a more family oriented development seems to occur in the presence of early post-delivery interaction.

Gender-related long-term effects in adult rats by perinatal dietary ratio of n-6/n-3 fatty acids

2005 ◽  
Vol 288 (3) ◽  
pp. R575-R579 ◽  
Author(s):  
Marina Korotkova ◽  
Britt G. Gabrielsson ◽  
Agneta Holmäng ◽  
Britt-Marie Larsson ◽  
Lars Å. Hanson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Linseed Oil ◽  
Maternal Diet ◽  
Perinatal Period ◽  
Late Gestation ◽  
Male Rats ◽  
Long Term Effects ◽  
Adult Rats ◽  
Serum Leptin

Epidemiological studies in humans have shown that perinatal nutrition affects health later in life. We have previously shown that the ratio of n-6 to n-3 polyunsaturated fatty acids (PUFA) in the maternal diet affects serum leptin levels and growth of the suckling pups. The aim of the present study was to investigate the long-term effects of various ratios of the dietary n-6 and n-3 PUFA during the perinatal period on serum leptin, insulin, and triacylglycerol, as well as body growth in the adult offspring. During late gestation and throughout lactation, rats were fed an isocaloric diet containing 7 wt% fat, either as linseed oil (n-3 diet), soybean oil (n-6/n-3 diet), or sunflower oil (n-6 diet). At 3 wk of age, the n-6/n-3 PUFA ratios in the serum phospholipids of the offspring were 2.5, 8.3, and 17.5, respectively. After weaning, all pups were given a standard chow. At the 28th postnatal wk, mean body weight and fasting insulin levels were significantly increased in the rats fed the n-6/n-3 diet perinatally compared with the other groups. The systolic blood pressure and serum triacylglycerol levels were only increased in adult male rats of the same group. These data suggest that the balance between n-6 and n-3 PUFA during perinatal development affects several metabolic parameters in adulthood, especially in the male animals.

Making Music and Masculinity in Vagrancy’s Shadow: Race, Wealth, and Malandragem in Post-Abolition Rio de Janeiro

2010 ◽  
Vol 90 (4) ◽  
pp. 591-625
Author(s):  
Marc A. Hertzman
Keyword(s):  
Rio De Janeiro ◽  
Mixed Race ◽  
Turn Of The Century ◽  
Gender And Sexuality ◽  
Free Society ◽  
Long Term Effects ◽  
Music Market ◽  
Black Poor ◽  
The Relationship

Abstract This article discusses strategies which Afro-Brazilian men used to distance themselves from demeaning assumptions and stereotypes attached to slavery and vagrancy in Rio de Janeiro. The piece focuses on the first 50 years after abolition (1888) but also shows how the ideologia da vadiagem—a set of ideas and stereotypes which defined black, poor, and mixed-race men and women as lazy and inferior—cast a long shadow deep into the twentieth century. The primary lens is the music market, which, beginning around the turn of the century, provided one of the earliest and most public venues in which black men were judged as members of a free society. Some musicians played samba and a number used malandragem, the lifestyle and ethos of flashy, masculine, malandro hustler figures, to cater to audience desires and also to distinguish themselves from caricatures of sickly, weak vadios (vagrants or idlers). Other artists rejected malandragem or only embraced it selectively, instead preferring a more toned-down “professional” look and demeanor meant to secure dignity and respect for themselves, their music, and the communities for which they served as figureheads. Eduardo das Neves, Moreno, Donga, Pixinguinha, Brancura, and Ismael Silva are among the musicians discussed here. By interpreting malandragem as a response to the ideologia da vadiagem, and as one of many identities and strategies employed by black entertainers, the article provides unique insights about the relationship between race, class, gender, and sexuality and a new way to understand the long-term effects of slavery and related assumptions about race and masculinity in Brazil.

Terrorism and tourism in Israel

2016 ◽  
Vol 23 (6) ◽  
pp. 1343-1352 ◽  
Author(s):  
Marion Karl ◽  
Gordon Winder ◽  
Alexander Bauer
Keyword(s):  
Time Lag ◽  
Research Model ◽  
Long Term Effects ◽  
Short Term ◽  
Event Tourism ◽  
Using Data ◽  
Terrorist Event ◽  
The Impact ◽  
The Relationship

While the relation between terrorism and tourism has been an important topic for tourism research, the questions whether terrorism affects tourism immediately and how long after a terrorism event tourism recovers are, as yet, not clearly answered. The aim of this article is to better understand the magnitude and temporal scale of the impact of terrorism on tourism. To this end, a research model differentiating between short-term and long-term effects of terrorism on tourism is developed and analyzed for the destination Israel using data on tourists from Germany. The results show both short-term and long-term impacts with a time lag between the terrorist event and the beginning of tourism decline of 1 or up to 6 months. An economic influence on the development of tourist arrivals was not detected, but seasonality plays an important role in the relationship between terrorism and tourism.

scholarly journals Perception of Voicing Cues by Children With Early Otitis Media With and Without Language Impairment

1996 ◽  
Vol 39 (1) ◽  
pp. 43-54 ◽  
Author(s):  
Paul Groenen ◽  
Thom Crul ◽  
Ben Maassen ◽  
Wim van Bon
Keyword(s):  
Otitis Media ◽  
Language Impairment ◽  
Auditory Processing ◽  
Otitis Media With Effusion ◽  
Discrimination Performance ◽  
Central Auditory Processing ◽  
Long Term Effects ◽  
History Of ◽  
The Relationship

Research on the relationship between early otitis media with effusion (OME), language impairment, and central auditory processing has been equivocal. Identification and discrimination tasks provide us with a sensitive method of assessing speech perception on both an auditory and a phonetic level. The present study examined identification and discrimination of initial bilabial stop consonants differing in voicing by 9-year-old children with a history of severe OME. The groups studied were controlled for language impairment. The ability of these children to perceive major and minor voicing cues was examined using multiple voicing cues. Long-term effects of OME were found for both identification and discrimination performance. Children with OME produced an overall inconsistency in categorization, which suggests poorer phonetic processing. Discrimination was measured by means of “just noticeable differences” (JND). Children with early OME experience demonstrated a greater mean JND than children without early OME experience. Finally, in cases of language impairment with early OME, there was no additional deterioration of auditory or phonetic processing. It appears that either early OME or language impairment can lead to poorer perception.

scholarly journals Benevolent Ageism: Exploring Its Boundary Conditions, Generalizability, and Correlates

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 568-569
Author(s):  
Toni Bisconti ◽  
Jennifer Sublett ◽  
Alison Chasteen
Keyword(s):  
Older Adults ◽  
Boundary Conditions ◽  
Cognitive Outcomes ◽  
Long Term Effects ◽  
Chinese Sample ◽  
Self Compassion ◽  
Stereotype Content ◽  
The Impact ◽  
The Relationship

Abstract Ageism is one of the few prejudices that is still socially condoned (Nelson, 2016). Given the aging population and the impact of internalizing ageist thoughts, this construct needs to be at the forefront for scientific examination. The long-term effects of ageism, particularly negative self-perceptions, lead to negative health and cognitive outcomes (Chasteen et al., 2015; Levy et al., 2002). One of the intricate components of ageism, however, is that it is often “benevolent”. Cuddy and colleagues developed the Stereotype Content Model (SCM) to describe how individuals are categorized based on varying degrees of warmth and competence. Unlike many devalued members of society who are viewed as low on both, older adults are viewed as having high warmth and low competence, leading to more overaccommodative treatment. The goal of the present symposium is to overview the ways in which researchers have dissected this more nuanced type of ageism. Specifically, two of the presenters will cover some of the boundary conditions of understanding age-based stereotypes and their malleability, examining them across ages and across genders. Additionally, one of our presenters will overview the validation of the Ambivalent Ageism Scale on a Chinese sample, lending support to its generalizability. Finally, our last presenter will overview the relationship between benevolent ageism and self-compassion to predict metamemory, given the pervasive stereotype that older adults suffer from severe cognitive decline. Themes and implications of these presentations will be discussed.

scholarly journals Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development

2008 ◽  
pp. S79-S88
Author(s):  
R Rokyta ◽  
A Yamamotová ◽  
R Šlamberová ◽  
M Franěk ◽  
Š Vaculín ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Postnatal Period ◽  
Long Term Effects ◽  
Perinatal Factors ◽  
Adult Rats ◽  
Factors Affecting ◽  
Dorsal Rhizotomy ◽  
Rat Pups ◽  
Factors Influencing

This review, which summarizes our findings concerning the long-term effects of pre-, peri- and postnatal factors affecting development, nociception and sensorimotor functions, focuses on three areas: 1) perinatal factors influencing nociception in adult rats were examined in rats with hippocampal lesions, after the administration of stress influencing and psychostimulant drugs (dexamethasone, indomethacine and methamphetamine); 2) the effect of pre- and early postnatal methamphetamine administration was shown to impair the development of sensorimotor functions tested in rat pups throughout the preweaning period; 3) the effect of extensive dorsal rhizotomy of the brachial plexus during the early postnatal period was studied with respect to neuropathic pain development and sensorimotor functions. The present study indicates that prenatal or neonatal stress, as well as various drugs, may disturb the development of the nociceptive system and cause long-term behavioral changes persisting to adulthood and that some types of neuropathic pain cannot be induced during the first two postnatal weeks at all. A mature nervous system is required for the development of the described pathological behaviors.

scholarly journals Peri-Operative Cerebral Regional Oxygen Saturation Variability and Short-Term Outcomes Following Cardiac Surgery in Neonates

2021 ◽  
Author(s):  
Maryam O. Abubakar ◽  
Santina A. Zanelli ◽  
Michael C. Spaeder
Keyword(s):  
Cardiac Surgery ◽  
Single Ventricle ◽  
Long Term Effects ◽  
Short Term ◽  
Neurodevelopmental Outcomes ◽  
Arch Obstruction ◽  
Neonatal Cardiac Surgery ◽  
The Relationship ◽  
Operative Monitoring

Abstract Decreased post-operative cerebral region oxygenation saturation (crSO2) variability, a surrogate for cerebral autoregulation, correlates with poor neurodevelopmental outcomes in neonates who undergo cardiac surgery. The goal of this study is to investigate the relationship between pre- and post-operative crSO2 variability in neonates requiring neonatal cardiac surgery for congenital heart disease (CHD). The variability of averaged 1-min crSO2 values was calculated for a minimum of 12h before and for the first 48h following cardiac surgery with cardiopulmonary by-pass in neonates between November 2019 and May 2021. The crSO2 variability increased by 9% with each additional postnatal day in the pre-operative monitoring period (p=0.009). There was a 40% decrease in crSO2 variability between the pre-and post-operative monitoring periods (p<0.001). There were no associations between the degree of decrease in crSO2 variability and CHD classification (aortic arch obstruction or single ventricle physiology). The crSO2 variability improves with each additional postnatal day but then decreases by almost half following cardiac surgery in neonates. We did not observe any association between pre-operative crSO2 variability and post-operative ventilator-free days, post-operative ICU days, or mortality.The long-term effects or significance of reduced crSO2 require further exploration.

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