scholarly journals First Clinical Case of Equine Parvovirus-Hepatitis-Related Theiler’s Disease in Asia

Viruses ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1917
Author(s):  
Jungho Yoon ◽  
Taemook Park ◽  
Ahram Kim ◽  
Jongyoung Park ◽  
Byung-Joo Park ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Blood Parameters ◽  
Etiologic Agent ◽  
Nested Polymerase Chain Reaction ◽  
Abdominal Ultrasonography ◽  
Viral Shedding ◽  
First Case ◽  
The Usa ◽  
History Of ◽  
Ns1 Gene

Equine parvovirus-hepatitis (EqPV-H) is a newly identified etiologic agent of Theiler’s disease (TD). We present a case of EqPV-H-related fulminant hepatitis in a 14-year-old thoroughbred mare in Korea. The mare had acute hepatopathy and gastrointestinal symptoms, with abnormal liver-related blood parameters. The horse was born in the USA and imported to Korea in 2017, with no history of administration of equine biological products after entry into Korea. The horse was diagnosed with EqPV-H-associated hepatitis after abdominal ultrasonography, laparotomy, and nested polymerase chain reaction (PCR) and in situ hybridization (ISH) assays. The serum, nasal swab, oral swab, and liver biopsy were positive for EqPV-H according to the PCR assay. Genetic analysis of the partial NS1 gene of EqPV-H showed a unique nucleotide substitution, distinct from that in previously deposited strains. EqPV-H DNA was found not only in hepatocytes but also in bile duct epithelium and Kupffer cells, particularly via ISH. To the best of our knowledge, this is the first case of EqPV-H-associated TD in Asia, providing the first clinical evidence for viral shedding from the mouth and nose, and identification of EqPV-H in the liver. This study contributes to a better understanding of the pathological features of EqPV-H-associated TD.

scholarly journals Human Babesiosis in Europe

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1165
Author(s):  
Anke Hildebrandt ◽  
Annetta Zintl ◽  
Estrella Montero ◽  
Klaus-Peter Hunfeld ◽  
Jeremy Gray
Keyword(s):  
Clinical Management ◽  
Diagnostic Tools ◽  
Genetic Characteristics ◽  
Susceptibility To Infection ◽  
First Case ◽  
The Usa ◽  
Life Threatening ◽  
History Of ◽  
Etiological Agents ◽  
Human Babesiosis

Babesiosis is attracting increasing attention as a worldwide emerging zoonosis. The first case of human babesiosis in Europe was described in the late 1950s and since then more than 60 cases have been reported in Europe. While the disease is relatively rare in Europe, it is significant because the majority of cases present as life-threatening fulminant infections, mainly in immunocompromised patients. Although appearing clinically similar to human babesiosis elsewhere, particularly in the USA, most European forms of the disease are distinct entities, especially concerning epidemiology, human susceptibility to infection and clinical management. This paper describes the history of the disease and reviews all published cases that have occurred in Europe with regard to the identity and genetic characteristics of the etiological agents, pathogenesis, aspects of epidemiology including the eco-epidemiology of the vectors, the clinical courses of infection, diagnostic tools and clinical management and treatment.

scholarly journals Laparoskopinė urachus cistų ir sinuso šalinimo operacija: du klinikiniai atvejai ir literatūros apžvalga

2012 ◽  
Vol 11 (3-4) ◽  
pp. 93-100
Author(s):  
Algirdas Žalimas ◽  
Audrius Gradauskas ◽  
Deividas Narmontas ◽  
Edmundas Štarolis ◽  
Sandra Selickaja
Keyword(s):  
Female Patient ◽  
Case Reports ◽  
Laparoscopic Approach ◽  
Invasive Technique ◽  
Attractive Alternative ◽  
Urachal Cyst ◽  
Abdominal Ultrasonography ◽  
Urachal Remnant ◽  
First Case ◽  
History Of

ĮžangaEmbrioninio šlapimo latako (urachus) anomalijos yra retos. Infekcija yra dažniausia jų komplikacija ir simptomų pasireiškimo priežastis. Simptomines urachus anomalijas reikia šalinti. Mes aprašome du klinikinius atvejus, kai sėkmingai pašalinta urachus cista ir sinusas laparoskopinės operacijos būdu. Mūsų turimais duomenimis, Lietuvoje atliktos pirmosios tokio pobūdžio operacijos.Atvejų pristatymasPirmas atvejis yra 55 metų amžiaus moters, kuri paguldyta į ligoninę dėl du mėnesius trunkančio padažnėjusio šlapinimosi. Atlikus pilvo echoskopiją, klaidingai nustatyta dešinės kiaušidės cistadenoma. Urachus cista buvo aptikta atlikus diagnostinę laparoskopiją, pilvo ir dubens kompiuterinę tomografiją. Antras atvejis yra 22 metų moters, kuri paguldyta į ligoninę dėl 10 dienų trunkančio pilvo skausmo ir bambos šlapiavimo. Pilvo echoskopijos metu žemiau bambos po pilvo siena buvo rastos dvi cistos – viena iš jų netoli šlapimo pūslės, kita atsiverianti į bambą. Remiantis atliktais tyrimais diagnozuota urachus cista ir sinusas. Abiem atvejais buvo atliktos laparoskopinės urachus cistų ir sinuso ekscizijos.IšvadosDaugelį metų urachus anomalijos buvo operuojamos atviruoju būdu, tačiau laparoskopinė operacija tapo gera alternatyva atvirosioms dėl silpnesnio pooperacinio skausmo, mažesnių randų, greitesnio sveikimo.Reikšminiai žodžiai: urachus cista, urachus sinusas, ekscizija, laparoskopinė operacija.Laparoscopic excision of urachal cysts and sinus: report of two cases and review of the literature IntroductionUrachal abnormalities are rare. Usually, they are incidental findings and remain asymptomatic unless a complication (most commonly infection) occurs. A complicated urachal anomaly needs to be removed. We introduce two successful case reports, according to our data the first laparoscopic urachal remnant excision in Lithuania.Cases presentationIn the first case, 55-year-old female patient presented with a two-month history of dysuria. Abdominal ultrasonography misdiagnosed the right ovarian cyst. Diagnostic laparoscopy and pelvic computer tomography showed an urachal cyst. In the second case, a 22-year-old female patient presented with a ten-day history of abdominal pain and umbilical discharge. Abdominal ultrasonography showed two cysts (the first cyst was found near the urinary bladder and the second cyst was connected with the umbilicus) under the anterior abdominal wall. According to clinical symptoms and ultrasound findings, urachus sinus and cyst were diagnosed. Laparoscopic urachal anomaly excision operations were performed to both patients.ConclusionsLaparoscopy is an effective and safe minimally invasive technique in the management of urachal anomalies. Open surgical excision has been the treatment of choice for many years, but the laparoscopic approach has become an attractive alternative because of less postoperative pain, better cosmetics, and rapid convalescence.Key words: urachal cyst, urachal sinus, excision, laparoscopic surgery.

scholarly journals A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl

2021 ◽  
pp. 78-78
Author(s):  
Milena Bjelica ◽  
Gordana Vilotijevic-Dautovic ◽  
Andrea Djuretic ◽  
Slobodan Spasojevic
Keyword(s):  
Gastrointestinal Symptoms ◽  
World Health ◽  
Nasopharyngeal Swab ◽  
First Case ◽  
Control And Prevention ◽  
Inflammatory State ◽  
Life Threatening ◽  
History Of ◽  
Health Organization ◽  
Inflammatory Syndrome

Introduction. Multisystem inflammatory syndrome in children (MIS-C) is a post-viral, life-threatening, inflammatory state with multisystem involvement that typically manifests 3-4 weeks after SARS-CoV-2 infection. In this article, we present the first case of MIS-C in the Institute for Child and Youth Health Care of Vojvodina at the beginning of the COVID-19 pandemic. Case outline. A previously 11-years-old healthy girl got sick two days before admission to the hospital with a fever, headache, vomiting, abdominal pain, and fatigue. She was tested positive for COVID-19 by nasopharyngeal swab PCR with positive IgM and IgG antibodies. In the further course the illness presented with prolonged fever, laboratory evidence of inflammation, multiorgan involvement such as respiratory, gastrointestinal, cardiovascular, and dermatologic. Based on Centers for Disease Control and Prevention and World Health Organization criteria the diagnosis of MIS-C was made and IVIG and methylprednisolone were introduced with favorable clinical course. Conclusion. Every prolonged and unusual febrile state, especially if it is accompanied by gastrointestinal symptoms, in a school-age child, should be investigated in the direction of recent COVID-19 infection or exposure. In a case of a positive COVID-19 history or history of exposure, the MIS-C diagnosis should be considered.

scholarly journals An Unconventional Diagnostic Method for Cryptosporidial Enteritis in a Healthy Host: Never Call It Quits!

2019 ◽  
Vol 13 (3) ◽  
pp. 526-531
Author(s):  
Shivantha Amarnath ◽  
Cheikh Talal El Imad ◽  
Kingsley Ebare ◽  
Hueizhi Wu ◽  
Stephen Mulrooney
Keyword(s):  
Diagnostic Method ◽  
Stool Culture ◽  
Watery Diarrhea ◽  
Peptic Ulcers ◽  
Unique Case ◽  
First Case ◽  
The Usa ◽  
History Of ◽  
Rising Incidence ◽  
Systemic Symptoms

Cryptosporidial enteritis has a rising incidence in the USA, mostly affecting immunocompromised individuals and children. It has a self-limiting course in healthy hosts. Herein, we present a unique case of a healthy middle-aged female who presented with a 1-month history of voluminous watery diarrhea and acute blood loss anemia. Cryptosporidial enteritis was diagnosed based on endoscopy with biopsy-proven evidence of 2 jejunal peptic ulcers infected with Cryptosporidiumspp. that was originally missed on routine stool culture, ova and parasite tests. The patient was successfully treated with nitazoxanide,and eradication of the protozoan was also confirmed on repeat endoscopic biopsies of the ulcer that were carried out 6 months later. To our knowledge, this is the first case to be reported in the literature with infective colonization of peptic ulcers with Cryptosporidiumspp.with consequent systemic symptoms.

Anorectal lymphogranuloma venereum in a Melbourne man

Sexual Health ◽  
2006 ◽  
Vol 3 (3) ◽  
pp. 189 ◽  
Author(s):  
Anna N. Morton ◽  
Christopher K. Fairley ◽  
Angelo M. Zaia ◽  
Marcus Y. Chen
Keyword(s):  
Anal Intercourse ◽  
Lymphogranuloma Venereum ◽  
First Case ◽  
Insertive Anal Intercourse ◽  
Recent Emergence ◽  
The Usa ◽  
Anal Swab ◽  
History Of ◽  
Sex With Men ◽  
High Index Of Suspicion

We report the first case of anorectal lymphogranuloma venereum (LGV) in a man who has sex with men (MSM) in Australia in the setting of the recent emergence of LGV among MSM in Europe and the USA. A 33-year-old man presented with a 2 month history of mild external anal discomfort. He gave a history of unprotected receptive and insertive anal intercourse with one partner in Europe during the preceding 6 months. No symptoms suggested proctitis and examination revealed two small anal fissures. An anal swab was positive for Chlamydia trachomatis; investigation for other STIs including HIV were negative. On review 6 days later, he was investigated and treated presumptively for LGV. The LGV diagnosis was confirmed by identifying the L2 serovar of C. trachomatis using a genotype test on the original anal specimen. This case is in keeping with the more recent reports of LGV from Europe, and has demonstrated the need for a high index of suspicion for asymptomatic or minimally symptomatic anorectal LGV.

Case Report: Management of a Patient with mTBI and Vestibular Hypofunction with the Binasal Occlusion Technique

2018 ◽  
pp. 87-90
Keyword(s):  
Case Report ◽  
Visual Motion ◽  
Hand Movement ◽  
Motion Sensitivity ◽  
Vestibular Hypofunction ◽  
First Case ◽  
Neurological Exam ◽  
History Of ◽  
Occlusion Technique ◽  
Visual Vertigo

Background: Binasal Occlusion (BNO) is a clinical technique used by many neurorehabilitative optometrists in patients with mild traumatic brain injury (mTBI) and increased visual motion sensitivity (VMS) or visual vertigo. BNO is a technique in which partial occluders are added to the spectacle lenses to suppress the abnormal peripheral visual motion information. This technique helps in reducing VMS symptoms (i.e., nausea, dizziness, balance difficulty, visual confusion). Case Report: A 44-year-old AA female presented for a routine eye exam with a history of mTBI approximately 33 years ago. She was suffering from severe dizziness for the last two years that was adversely impacting her ADLs. The dizziness occurred in all body positions and all environments throughout the day. She was diagnosed with vestibular hypofunction and had undergone vestibular therapy but reported little improvement. Neurological exam revealed dizziness with both OKN drum and hand movement, especially in the left visual field. BNO technique resulted in immediate relief of her dizziness symptoms. Conclusion: To our knowledge, this is the first case that illustrates how the BNO technique in isolation can be beneficial for patients with mTBI and vestibular hypofunction. It demonstrates the success that BNO has in filtering abnormal peripheral visual motion in these patients.

Socio-Technological Aspects of Automation in Public Works Activities

1987 ◽  
Vol 19 (3-4) ◽  
pp. 633-643
Author(s):  
William F. Garber
Keyword(s):  
Industrial Revolution ◽  
Work Force ◽  
Public Works ◽  
Human Society ◽  
Training Problem ◽  
Total Employment ◽  
The Usa ◽  
History Of ◽  
Complete Automation ◽  
The Impact

The history of human society is replete with examples of advances in technology overrunning the ability of societal organizations to efficiently handle the resulting massive societal dislocations. The social impacts of the “Industrial Revolution of the 18th and 19th Centuries” illustrate how profound such effects can be. The automation-computer-robotics revolution now underway also has the potential for serious societal changes. In this regard public works activities are subject to increasing amounts of automation with impacts upon current and net total employment and training needs. To evaluate the present status of automation in the USA, questionnaires were sent to public works authorities in 110 cities or agencies. The current degree of automation, the impact upon employment and the skills now needed by public works employers were queried. It was found that in most cases automation was just starting; but that as complete automation as was possible was inevitable given the increasing complexity of the tasks, the demands of the public and the long term prospects for public works funding. In many cases the candidates now in the work force were not properly trained for automation needs. Retraining and changes in the educational system appeared necessary if the employees now needed were to be continuously available. Public works management as well as several labor organizations appeared to be aware of this need and were organizing to handle the training problem and the changes in employment qualifications now necessary. It appeared to be a consensus that the larger societal effects of automation should be handled by society as a whole.

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