scholarly journals Utilidad de los métodos diagnósticos en detección de cáncer tiroideo

2017 ◽  
Vol 1 (2) ◽  
pp. 52
Author(s):  
Rasiel Acosta Pérez ◽  
Bárbara Dinora Hidalgo Martínez ◽  
Carlos Pomerio Zambrano Cedeño ◽  
Deiber Gámez Brito
Keyword(s):  
Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Preoperative Evaluation ◽  
Stage Iv ◽  
Needle Aspiration ◽  
Diagnostic Methods ◽  
Hospital Data ◽  
Cross Sectional ◽  
Fine Needle ◽  
Clinical Records

El cáncer de tiroides es la neoplasia endocrina más frecuente. Con el objetivo de determinar la utilidad de los métodos diagnósticos de cáncer de tiroides se realizó un estudio descriptivo trans- versal con 17 pacientes diagnosticados en el periodo septiembre 2015-2016, en la consulta externa del Hospital Humberto Pozo del cantón Guaranda, provincia de Bolívar. De las historias clínicas se extrajeron los datos: edad, sexo, diagnósticos clínicos, ecográfico, citológico e histológico. Pre- dominó el género femenino, siendo el carcinoma papilar la variante histológica más diagnosticada (70,7%). El grupo de edades más representativo, se encontró entre 51-60 años. El mayor número de cánceres (64,8 %) se diagnosticó en el estadio IV. La sensibilidad para la punción aspiración con aguja fina se ubicó en 94,1% y, las lesiones sólidas en la ecografía predominaron en el 70,6%. Estos resultados permitieron evidenciar que la punción aspiración con aguja fina y la ecografía son procedimientos útiles en la evaluación preoperatoria de la patología tiroidea. Palabras clave: neoplasia de tiroides, nódulo tiroideo, punción aspiración con aguja fina Abstract Thyroid cancer is the most common endocrine neoplasia. In order to determine the usefulness of diagnostic methods for detection of thyroid cancer, a cross-sectional descriptive study was per- formed with 17 patients diagnosed in the period from September 2015 to 2016, at the outpatient clinic Humberto Pozo of canton Guaranda Hospital. Data were extracted from the following clinical records: age, gender, clinical, ultrasound, cytological and histological diagnoses. The female gen- der predominated, papillary carcinoma being the most diagnosed histological variant (70.7%). The group of 51-60 years was the most representative. The largest number of cancers (64.8%) was diagnosed in stage IV. Sensitivity for fine needle aspiration was of 94.1% and solid lesions on ul- trasound predominated in 70.6%. Fine needle aspiration and ultrasonography proved to be useful procedures in the preoperative evaluation of thyroid pathology.  Key words: Thyroid neoplasias, thyroid nodules, fine needle aspiration biopsy  

scholarly journals Utilidad de los métodos diagnósticos en detección de cáncer tiroideo

2017 ◽  
Vol 1 (2) ◽  
pp. 52
Author(s):  
Rasiel Acosta Pérez ◽  
Bárbara Dinora Hidalgo Martínez ◽  
Carlos Pomerio Zambrano Cedeño ◽  
Deiber Gámez Brito
Keyword(s):  
Thyroid Cancer ◽  
Fine Needle Aspiration ◽  
Preoperative Evaluation ◽  
Stage Iv ◽  
Needle Aspiration ◽  
Diagnostic Methods ◽  
Hospital Data ◽  
Cross Sectional ◽  
Fine Needle ◽  
Clinical Records

El cáncer de tiroides es la neoplasia endocrina más frecuente. Con el objetivo de determinar la utilidad de los métodos diagnósticos de cáncer de tiroides se realizó un estudio descriptivo trans- versal con 17 pacientes diagnosticados en el periodo septiembre 2015-2016, en la consulta externa del Hospital Humberto Pozo del cantón Guaranda, provincia de Bolívar. De las historias clínicas se extrajeron los datos: edad, sexo, diagnósticos clínicos, ecográfico, citológico e histológico. Pre- dominó el género femenino, siendo el carcinoma papilar la variante histológica más diagnosticada (70,7%). El grupo de edades más representativo, se encontró entre 51-60 años. El mayor número de cánceres (64,8 %) se diagnosticó en el estadio IV. La sensibilidad para la punción aspiración con aguja fina se ubicó en 94,1% y, las lesiones sólidas en la ecografía predominaron en el 70,6%. Estos resultados permitieron evidenciar que la punción aspiración con aguja fina y la ecografía son procedimientos útiles en la evaluación preoperatoria de la patología tiroidea. Palabras clave: neoplasia de tiroides, nódulo tiroideo, punción aspiración con aguja fina Abstract Thyroid cancer is the most common endocrine neoplasia. In order to determine the usefulness of diagnostic methods for detection of thyroid cancer, a cross-sectional descriptive study was per- formed with 17 patients diagnosed in the period from September 2015 to 2016, at the outpatient clinic Humberto Pozo of canton Guaranda Hospital. Data were extracted from the following clinical records: age, gender, clinical, ultrasound, cytological and histological diagnoses. The female gen- der predominated, papillary carcinoma being the most diagnosed histological variant (70.7%). The group of 51-60 years was the most representative. The largest number of cancers (64.8%) was diagnosed in stage IV. Sensitivity for fine needle aspiration was of 94.1% and solid lesions on ul- trasound predominated in 70.6%. Fine needle aspiration and ultrasonography proved to be useful procedures in the preoperative evaluation of thyroid pathology.  Key words: Thyroid neoplasias, thyroid nodules, fine needle aspiration biopsy  

scholarly journals Pleomorphic Adenoma of the Submandibular Gland in a 10-Year-Old Child: A Case Report

2021 ◽  
pp. 014556132110221
Author(s):  
Bouatay Rachida ◽  
Ons Kharrat ◽  
Wiem Boughzala ◽  
Seifeddine Ben Hammouda ◽  
Nouha Ben Abdeljelil ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Pleomorphic Adenoma ◽  
Fine Needle Aspiration ◽  
Histopathological Examination ◽  
Preoperative Evaluation ◽  
Needle Aspiration ◽  
Magnetic Resonance Images ◽  
Fine Needle ◽  
Sebaceous Cyst ◽  
Growing Mass

We report the case of a 10-year-old girl with a painless slowly growing mass that had developed over the course of 2 years in the left submandibular area. Physical examination revealed a firm painless submandibular mass with no other associated signs. Ultrasound graphics were in favor of a sebaceous cyst. Fine-needle aspiration and magnetic resonance images (MRI) concluded to a pleomorphic adenoma of the submandibular gland. The patient underwent left submandibulectomy. Histopathological examination confirmed the diagnosis of pleomorphic adenoma arising from the submandibular gland. The postoperative course was uneventful. Pleomorphic adenoma of the submandibular gland represents a diagnostic and therapeutic dilemma in children. Preoperative evaluation, including MRI and fine-needle aspiration, is recommended. Total submandibulectomy is also recommended to minimize recurrences and to avoid malignant transformation.

scholarly journals Predictive Factors of Malignancy in Cytology of Indeterminate Follicular and Hürthle Cell Neoplasms of the Thyroid Gland

2019 ◽  
Vol 103 (1-2) ◽  
pp. 9-14
Author(s):  
Bahadır Öz ◽  
Serap Doğan ◽  
Ertan Emek ◽  
Muhammed Akyüz ◽  
Alper Akcan ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Family History ◽  
Radiation Exposure ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Cytologic Diagnosis ◽  
Fine Needle ◽  
Solitary Nodule ◽  
History Of

The objective of the current study was to determine the risk of malignancy in patients with thyroid nodules with cytology of indeterminate follicular and indeterminate Hürthle cell neoplasm (HN). The cytologic diagnosis of follicular neoplasm (FN) or HN remains a diagnostic challenge. Often, surgery is recommended for such lesions. A retrospective analysis was performed on 80 patients who underwent thyroid surgery following a diagnosis of indeterminate FN and indeterminate HN in thyroid fine-needle aspiration biopsy. Sex; age; family history of thyroid cancer and radiation exposure; coexisting thyroid conditions, such as solitary nodule; multinodularity; cytologic diagnosis; sonographic features; type of surgical treatment; and histopathologic results were recorded. Of the 80 patients, 52 (65%) had FN on fine-needle aspiration biopsy cytology and 28 (35%) had HN. A total of 23 patients (28.7%) had primary thyroid cancers on surgical pathology, and 57 (71.3%) had benign diagnoses. Univariate analysis showed no differences between the benign and malignant groups by sex, nodule size, family history of thyroid cancer, history of radiation exposure, presence of solitary nodule or multinodularity in the nodular features. In multivariate binary logistic regression analysis, the factors that were statistically significant predictors of malignancy were microcalcification [odds ratio (OR), 10.9; 95% confidence interval (CI), 2.18–54.7; P = 0.004], being older than 45 years (OR, 4.2; 95% CI, 1.25–14.63; P = 0.02]. The independent predictors of malignancy in FN and HN are micorcalcification and being older than 45 years, the use of which may predict the risk of thyroid cancer.

Molecular Diagnostics of Thyroid Tumors

2011 ◽  
Vol 135 (5) ◽  
pp. 569-577 ◽  
Author(s):  
Yuri E. Nikiforov
Keyword(s):  
Thyroid Cancer ◽  
Molecular Markers ◽  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Genetic Alterations ◽  
Braf V600e ◽  
Fine Needle ◽  
Molecular Alterations ◽  
Diagnostic Use

Abstract Context.—Thyroid cancer is the most common type of endocrine malignancy and its incidence is steadily increasing. Papillary carcinoma and follicular carcinoma are the most common types of thyroid cancer and represent those tumor types for which use of molecular markers for diagnosis and prognostication is of high clinical significance. Objective.—To review the most common molecular alterations in thyroid cancer and their diagnostic and prognostic utility. Data Sources.—PubMed (US National Library of Medicine)–available review articles, peer-reviewed original articles, and experience of the author. Conclusions.—The most common molecular alterations in thyroid cancer include BRAF and RAS point mutations and RET/PTC and PAX8/PPARγ rearrangements. These nonoverlapping genetic alterations are found in more than 70% of papillary and follicular thyroid carcinomas. These molecular alterations can be detected in surgically resected samples and fine-needle aspiration samples from thyroid nodules and can be of significant diagnostic use. The diagnostic role of BRAF mutations has been studied most extensively, and recent studies also demonstrated a significant diagnostic utility of RAS, RET/PTC, and PAX8/PPARγ mutations, particularly in thyroid fine-needle aspiration samples with indeterminate cytology. In addition to the diagnostic use, BRAF V600E mutation can also be used for tumor prognostication, as this mutation is associated with higher rate of tumor recurrence and tumor-related mortality. The use of these and other emerging molecular markers is expected to improve significantly the accuracy of cancer diagnosis in thyroid nodules and allow more individualized surgical and postsurgical management of patients with thyroid cancer.

Sign in / Sign up

Export Citation Format

Share Document