scholarly journals GAMBARAN KADAR KREATININ SERUM PADA PENDERITA DIABETES MELLITUS TIPE 2 DI RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Ida Arjani
Keyword(s):  
Diabetes Mellitus ◽  
Renal Function ◽  
Serum Creatinine ◽  
Analytical Study ◽  
Sampling Methods ◽  
Chronic Complications ◽  
Low Levels ◽  
End Stage ◽  
Dm Type 2

ABSTRACTBackground Diabetes mellitus (DM) is a metabolic disease which characterized by hyperglycemia due to abnormalities insulin secretions, insulin performance, or both of them. The condition of insulin resistance in DM type 2 causes chronic complications such as diabetic nephropathy. It has become the second leading cause of end-stage kidney disease, and one of the most common and demaging complication of diabetes. The level of creatinine in blood is one of the parameters used to assess renal function, as in the plasma concentration and excretion in the urine within 24 hours. Serum creatinine levels greater than the normal value suggests an impaired renal function. Objective The purpose of this study was to determine serum creatinine levels in patients with DM type 2 in Sanglah General Hospital Denpasar. Methods The method uses an analytical study with description, used accidental sampling methods, involving 30 patients with DM type 2. Blood samples were analyzed for creatinine levels and data are presented as table. The reslts  of this study showed that 60% samples had high levels of serum creatinine, 30% samples had normal levels serum creatinine, and 10% samples had low levels serum creatinine. From the result was concluded, most patients with DM type 2 in Sanglah Genaral Hospital have highly serum creatinine levels.                                                        Keywords: creatinine serum, DM type 2

Diabetes mellitus type 2 personality and relations with diabetic chronic complications–Pilot study

2017 ◽  
Vol 41 (S1) ◽  
pp. s507-s507
Author(s):  
M. Stoimenova-Popova ◽  
M. Valkova ◽  
I. Veleva ◽  
L. Tumbev ◽  
P. Chumpalova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Minnesota Multiphasic Personality Inventory ◽  
Urine Analysis ◽  
Neuropsychological Battery ◽  
Chronic Complications ◽  
Personality Changes ◽  
Competing Interest ◽  
Dm Type 2

IntroductionDiabetes mellitus (DM) is associated with chronic complications and comorbidities. Psychopathology and personality changes (PCh) are also found in DM. Some authors suggest organic PCh. The aim of our study was to access DM associated PCh and their relations with DM complications, glycemic control (GC) and family history for DM (FH).Material and methodsWe examined 47 patients with DM type 2 (64.65 ± 9.78 years old; 14 males, 33 females; 24 with and 23 without FH, 20 with good, 15 with poor and 12 with very poor GC). All of them underwent somatic and neurological examinations. Blood count and biochemistry, urine analysis, brain computer tomography, electroneurography, electrocardiography and neuropsychological battery were applied. PCh were accessed by Minnesota Multiphasic Personality Inventory.ResultsThe most frequent PCh were hypochondriasis (Hs, 77%), hysteria (Xy, 74%) and schizoidia (Se; 77%); hypomania was low in 60%; 30% showed low psychasthenia and 49% low psychopatia. High paranoia had 23% and low–15%. Poor GC was associated with cognitive impairment (CI) and high Hs, Xy and Se. Patients with high Hs, Xy and Se showed more frequent diabetic complications (retinopathy, polyneuropathy and nephropathy), comorbidities and CI than those without, even after correction for age, therapy and DM duration. FH was risk factor for PCh.ConclusionsPatients with DM show specific PCh. High scoring on Hs, Xy and Se scales are associated with poor GC, chronic DM complications, comorbidities and CI. FH is risk factor for PCh.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Study of Correlation between Renal Function Test and Severity of Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus

2021 ◽  
Vol 10 (20) ◽  
pp. 1511-1514
Author(s):  
Archana Ramkrishna Thool ◽  
Nikunj Kishore Dhande ◽  
Sachin Vishwanath Daigavane
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Renal Function ◽  
Diabetic Retinopathy ◽  
Serum Creatinine ◽  
Blood Urea Nitrogen ◽  
Glycosylated Haemoglobin ◽  
Function Test

BACKGROUND Retinopathy and nephropathy are chronic vascular complications of type 2 diabetes mellitus, this eventually leads to end stage renal disease and blindness. Diabetic retinopathy is an important cause of legal blindness in 20 - 70 years. The purpose of the study was to establish association between severity of diabetic retinopathy with systemic levels of glycosylated haemoglobin and renal function test. METHODS This is a cross sectional study conducted among 75 patients with type 2 diabetes mellitus attending the ophthalmology out-patient department (OPD) of Acharya Vinoba Bhave Hospital, Wardha and patients referred from the hospital. Detailed fundus examination and staging of diabetic retinopathy (DR) was done. Glycosylated haemoglobin levels, serum creatinine and blood urea nitrogen were measured. RESULTS Majority of patients were in the age range of 61 to 70 years. Mean ± SD of 3 parameters in patients with no DR, mild non-proliferative diabetic retinopathy (NPDR), moderate NPDR, severe NPDR and proliferative diabetic retinopathy (PDR) were as follows: Serum creatinine 1.12 ± 0.41, 1.21 ± 0.53, 1.35 ± 0.49, 1.55 ± 0.22 and 1.70 ± 0.23 respectively. P = 0.007. Blood urea nitrogen (BUN) 28.62 ± 4.20, 31.83 ± 7.20, 37.31 ± 12.57, 44.21 ± 7.53 and 48.76 ± 5.08 respectively. P = 0.0001. HbA1c l, 6.72 ± 0.60, 8.14 ± 0.98, 8.52 ± 2.67, 9.96 ± 1.22 and 12.14 ± 1.96 respectively. P = 0.0001. All the 3 parameters were statistically significant. 40 % of cases had clinically significant macular oedema. CONCLUSIONS Poor glycaemic control as seen by higher levels of glycosylated haemoglobin and deranged renal function is associated with severe form of DR. KEY WORDS Diabetes Mellitus, Diabetic Retinopathy, Serum Creatinine HbA1c and BUN

scholarly journals Effects of ertugliflozin on kidney composite outcomes, renal function and albuminuria in patients with type 2 diabetes mellitus: an analysis from the randomised VERTIS CV trial

Diabetologia ◽  
2021 ◽  
Author(s):  
David Z. I. Cherney ◽  
◽  
Bernard Charbonnel ◽  
Francesco Cosentino ◽  
Samuel Dagogo-Jack ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Kidney Disease ◽  
Serum Creatinine ◽  
Renal Dialysis ◽  
Composite Endpoint ◽  
Composite Outcome ◽  
The Impact

Abstract Aims/hypothesis In previous work, we reported the HR for the risk (95% CI) of the secondary kidney composite endpoint (time to first event of doubling of serum creatinine from baseline, renal dialysis/transplant or renal death) with ertugliflozin compared with placebo as 0.81 (0.63, 1.04). The effect of ertugliflozin on exploratory kidney-related outcomes was evaluated using data from the eValuation of ERTugliflozin effIcacy and Safety CardioVascular outcomes (VERTIS CV) trial (NCT01986881). Methods Individuals with type 2 diabetes mellitus and established atherosclerotic CVD were randomised to receive ertugliflozin 5 mg or 15 mg (observations from both doses were pooled), or matching placebo, added on to existing treatment. The kidney composite outcome in VERTIS CV (reported previously) was time to first event of doubling of serum creatinine from baseline, renal dialysis/transplant or renal death. The pre-specified exploratory composite outcome replaced doubling of serum creatinine with sustained 40% decrease from baseline in eGFR. In addition, the impact of ertugliflozin on urinary albumin/creatinine ratio (UACR) and eGFR over time was assessed. Results A total of 8246 individuals were randomised and followed for a mean of 3.5 years. The exploratory kidney composite outcome of sustained 40% reduction from baseline in eGFR, chronic kidney dialysis/transplant or renal death occurred at a lower event rate (events per 1000 person-years) in the ertugliflozin group than with the placebo group (6.0 vs 9.0); the HR (95% CI) was 0.66 (0.50, 0.88). At 60 months, in the ertugliflozin group, placebo-corrected changes from baseline (95% CIs) in UACR and eGFR were −16.2% (−23.9, −7.6) and 2.6 ml min−1 [1.73 m]−2 (1.5, 3.6), respectively. Ertugliflozin was associated with a consistent decrease in UACR and attenuation of eGFR decline across subgroups, with a suggested larger effect observed in the macroalbuminuria and Kidney Disease: Improving Global Outcomes in Chronic Kidney Disease (KDIGO CKD) high/very high-risk subgroups. Conclusions/interpretation Among individuals with type 2 diabetes and atherosclerotic CVD, ertugliflozin reduced the risk for the pre-specified exploratory composite renal endpoint and was associated with preservation of eGFR and reduced UACR. Trial registration ClinicalTrials.gov NCT01986881 Graphical abstract

scholarly journals HUBUNGAN KUALITAS TIDUR DENGAN KADAR GLUKOSA DARAH PUASA PADA PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS KASSI-KASSI KOTA MAKASSAR

2020 ◽  
Vol 15 (1) ◽  
pp. 46-50
Author(s):  
Muhammad Basri ◽  
Baharuddin K ◽  
Sitti Rahmatia
Keyword(s):  
Diabetes Mellitus ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Dm Type 2 ◽  
Diabetes Melitus

Diabetes Melitus (DM) merupakan salah satu kelompok penyakit metabolik dan kronis dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau keduaduanya yang membutuhkan perawatan medis dan pendidikan pengelolaan mandiri untuk mencegah komplikasi akut jangka panjang (Nian, 2017). Tujuan penelitian ini adalah Mendeskripsikan hubungan kualitas tidur dengan kadar glukosa darah Puasa pada pasien DM tipe II di PKM Kassi-Kassikota Makassar. Manfaat : Meningkatkan pengetahuan pada Penderita DM Tipe II yang mengalami gangguan Kwalitas dan Pola Tidur shari-hari Meningkatkan pengetahuan pada Penderita DM Tipe II yang mengalami gangguan Kwalitas dan Pola Tidur shari-hari Metode : Pada penelitian ini menggunakan desain cross sectional, jenis penelitian ini menggunakan metode analitik yaitu metode penelitian yang dilakukan dengan tujuan untuk mengetahui hubungan antara Kualitas tidur dengan kadar glukosa darah puasa pada pasien DM Tipe II. Sampel menggunakan purposive sampling dengan menggunakan rumus Slovin dengan jumlah sampel  55  orang  yaitu  seluruh pasien DM tipe 2 yang menjalani rawat jalan di PKM Kassi-Kassi Kota Makassar. Hasil Uji Statistik Chi Square diperoleh p value 0,000 < 0,05.sehingga peneliti berasumsi bahwa  ada hubungan antara kualitas tidur dengan kadar glukosa darah pada pasien DM Type 2 di Puskesmas Kassi-Kassi Makassar.  Kesimpulan yaitu terdapat hubungan kualitas tidur dengan kadar glukosa darah pada pasien diabetes melitus tipe 2 di Puskesmas Kassi-Kassi Makassar. Saran dapat dijadikan sebagai salah satu acuhan bagi pasien diabetes melitus tipe 2 untuk meningkatkan kualitas tidur dan menjaga kadar glukosa darah puasa

Sign in / Sign up

Export Citation Format

Share Document