Progression of a 2nd type diabetes mellitus model on mice with usage of a calorie diet

2021 ◽  
Author(s):  
N.O. Fokeeva ◽  
O.V. Yakovleva
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
The Body ◽  
Key Words Diabetes Mellitus ◽  
Key Words Diabetes ◽  
Tactile Sensitivity ◽  
Calorie Diet ◽  
Mass Coefficient ◽  
Sugar Levels

Type 2 diabetes accounts for up to 90% of all diabetes cases. It is known that people with type 2 diabetes are often obese. Long-term complications also include problems with the cardiovascular, nervous and urinary systems. The model of type 2 diabetes mellitus based on a diet rich of fat and carbohydrates was used in the work. We observed a significant increase in the body weight of mice and sugar levels in their blood. Morphometric analysis of the pancreas showed an increase of its mass coefficient. Tactile sensitivity measurement showed an increase in its threshold. The developed model is quite suitable for analyzing the diabetes progression and its side effects on the body. Key words: diabetes mellitus type 2, obesity, pancreas, tactile sensitivity.

scholarly journals ANALISIS DRUG RELATED PROBLEMS (DRPs) PADA PASIEN RAWAT JALAN DIABETES MELITUS TIPE 2 DI UPT PUSKESMAS RAWAT INAP GEDONG AIR BANDAR LAMPUNG

2021 ◽  
Vol 9 (2) ◽  
pp. 134-142
Author(s):  
Akhmad Rokiban ◽  
◽  
Dwiauliaramdini Dwiauliaramdini ◽  
Sitijuwariyah Sitijuwariyah
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Drug Interactions ◽  
The Body ◽  
Key Words Diabetes Mellitus ◽  
Key Words Diabetes ◽  
Potential Drug ◽  
Drug Related Problems

Abtract Diabetes mellitus (DM) is a serious chronic disease that occurs because the pancreas does not produce enough insulin or when insulin is not use effectively in the body. This study aims to analyze the incidence of Drug Related Problems (DRPs) and find out the category of DRPs in outpatients with a diagnosis of type 2 diabetes mellitus at UPT Puskesmas Gedong Air Inpatient for the Bandar Lampung. This research is a nonexperimental research with a descriptive design taken retrospectively. The sampling technique used in this study is total sampling based on the patient's medical record data. Data were analyzed using the classification of DRPs according to Cipolle 2004, then using Medscape Tools as a tool to check potential drug interactions. The results of this study were 61 patients including 29 patients (46%) with DRPs and 33 patients (54%) without DRPs. The number of male patients is 25 patients and the number of female patients is 36 patients with age range 25-45 and 46-65. A total 52 patien Type 2 Diabetes Mellitus have cormobid and 9 patients without comorbid. DRP categories that occur include drugs without indication as much (8%), indications without drugs as much as (15%), and potential drug interactions (48%). The conclusion in this study is that Drug Related Problems (DRPs) have occurred in outpatients diagnosed with type 2 diabetes mellitus in UPT Puskesmas Gedong Air Inpatient with the highest DRPs category is the potential for drug interactions (48%). Key words: Diabetes Mellitus Type 2, Drug Related Problems

scholarly journals The Effect of Prolanis Exercise Activities on Decreasing Blood Sugar Levels in Diabetes Mellitus Patients

2021 ◽  
Vol 2 (2) ◽  
pp. 51-57
Author(s):  
Fitria Silvia ◽  
Mappeaty Nyorong ◽  
Miskah Afriany ◽  
Lucia Lastiur
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Physical Exercise ◽  
Blood Sugar ◽  
The Body ◽  
P Value ◽  
Electrolyte Balance ◽  
Control Groups ◽  
Sugar Levels

Diabetes exercises are physical exercises designed according to age and physical status and are part of the treatment of diabetes mellitus. When a person does physical exercise in the muscles of the body, the heart system and blood circulation and breathing are activated. Therefore, the body's metabolism, fluid and electrolyte balance and acid base must adjust. Muscles will use free fatty acids and glucose as a source of energy or energy. When physical exercise begins glucose originating from muscle-muscled glycogen when physical exercise starts being used as a source of energy. Assessing the effect of the implementation of prolanis exercise activities on reducing blood sugar levels in patients with Type 2 Diabetes Mellitus in Puskesmas Padangmatinggi in 2019. This type of research is quantitative with a quasi-experimental design that designs using one group pretest-posttest, when this study was conducted in January-April year 2020. The population in this study were all patients with diabetes mellitus who follow prolanis gymnastics in Padangmatinggipuskesmas with purposive sampling technique, namely the determination of the sample by specifying specific characteristics consisting of 15 intervention / experimental groups and 15 control groups 15 people The results showed that there was an effect of the application of prolanic exercise activities to reduce blood sugar levels in patients with type 2 diabetes at Padangmatingi Public Health Center in Padangsidimpuan with a P-Value of 0.007, and there were differences in blood sugar levels in the intervention and control groups with a P. Value of 0,000.

scholarly journals Relationship Of Stress Levels And Diet With Blood Sugar Levels In Patients Of Type 2 Diabetes Mellitus

2020 ◽  
Vol 9 (1) ◽  
pp. 241-247
Author(s):  
Ninik Ambar Sari ◽  
Ceria Nurhayati ◽  
Sri Anik Rustini
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Fasting Blood Glucose ◽  
Sampling Technique ◽  
The Body ◽  
Cross Sectional ◽  
Sugar Levels

Diabetes mellitus type 2 is a condition in which the body tissue doesn’t respond to the action of insulin. Type 2 DM can cause complications if it doesn’t managed properly, good DM management behavior for patients needs to be done by maintaining a healthy diet and stress will increase blood sugar levels. This study uses analytic cross sectional design. The sampling technique in this study was purposive sampling of 60 respondents. Data processing using the SPSS program with the Spearman Rho test. Results: a correlation between stress level and fasting blood glucose level of type 2 diabetes mellitus patients with a correlation value of 0.544, which is located between 0.4 - <0.6, is in the medium category. While the statistical test for diet obtained a significant number or ρ = 0.002 then Ho is rejected, H1 is accepted.

scholarly journals Does 'Honeymoon Period' Exist in Type 2 Diabetes Mellitus?

1970 ◽  
Vol 2 (2) ◽  
pp. 67-69
Author(s):  
SM Ashrafuzzaman ◽  
Zafar A Latifd
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Therapy ◽  
Type 1 Diabetes Mellitus ◽  
Key Words Diabetes Mellitus ◽  
Key Words Diabetes

Temporary remission of type 1 diabetes mellitus (T1DM) occurs following initiation of insulin therapy. This period of temporary remission without insulin therapy is called ‘honeymoon period'. But no such temporary remission usually occurs in type 2 diabetes (T2DM). We report here two cases of type 2 diabetes mellitus where such honey moon period was observed. Ibrahim Med. Coll. J. 2008; 2(2): 67-69   Key words: Diabetes Mellitus doi: 10.3329/imcj.v2i2.2942  

Penerapan Senam Kaki Diabetik Untuk Menurunkan Kadar Gula Darah Pada Pasien Diabetes Melitus Tipe 2

2021 ◽  
Vol 1 ◽  
pp. 1686-1690
Author(s):  
M. Zakky Febriyan ◽  
I Isytiaroh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetic Foot ◽  
Health Workers ◽  
The Body ◽  
Sugar Levels

AbstractDiabetes mellitus is a condition of increasing blood sugar levels that exceed 140 mg/dl. The purpose of this case study is to describe the application of giving diabetic foot exercises to reduce blood sugar levels in the body in patients with type 2 diabetes mellitus. The design of this scientific paper uses a case study method with 2 clients suffering from type 2 diabetes mellitus with blood sugar above 140 mg. /dl in Poncol Village and in Karangsari Village, Batang Regency. The intervention carried out was giving diabetic foot exercises for 4 days and once a day. Evaluation was carried out to determine the decrease in blood glucose using a glucometer. The results of the study showed a decrease in blood sugar in both clients, for client 1 there was a decrease in blood sugar from 220mg/dl to 135mg/dl and for client 2 there was a decrease in blood sugar from 250mg/dl to 137mg/dl. The conclusion of this case study shows that diabetic foot exercises can reduce blood sugar levels in patients with type 2 diabetes mellitus. Suggestions for health workers are expected to teach diabetic foot exercises to reduce blood sugar levels in patients with type 2 diabetes mellitus.Keywords: blood sugar, diabetes mellitus, foot exercise AbstrakDiabetes mellitus merupakan kondisi kenaikan kadar gula darah yang melebihi 140mg/dl. Tujuan dari studi kasus ini adalah menggambarkan penerapan pemberian senam kaki diabetik untuk menurunkan kadar gula darah dalam tubuh pada penderita diabetes mellitus tipe 2. Rancangan karya tulis ilmiah ini menggunakan metode studi kasus dengan subjek 2 klien yang menderita diabetes mellitus tipe 2 dengan gula darah diatas 140mg/dl di Desa Poncol dan di Desa Karangsari Kabupaten Batang. Intervensi yang dilakukan adalah pemberian tindakan senam kaki diabetik selama 4 hari dan dilakukan satu kali sehari. Evaluasi dilakukan untuk mengetahui penurunan glukosa darah menggunakan alat ukur glukometer Hasil studi menunjukan adanya penurunan gula darah dalam tubuh pada kedua klien, untuk klien 1 mengalami penurunan gula darah dari 220mg/dl menjadi 135mg/dl dan untuk klien 2 mengalamai penurunan gula darah dari 250mg/dl menjadi 137mg/dl. Simpulan studi kasus ini menunjukan bahwa senam kaki diabetik mampu menurunkan kadar gula darah pada penderita diabetes mellitus tipe 2. Saran bagi tenaga kesehatan diharapkan mengajarkan senam kaki diabetik untuk menurunkan kadar gula darah pada penderita diabetes mellitus tipe 2. Kata kunci : diabetes mellitus, gula darah, senam kaki

scholarly journals The risk factors of depression in patients with type 2 Diabetes Mellitus

2019 ◽  
Vol 27 (3) ◽  
pp. 65
Author(s):  
Mariana Shevchuk ◽  
Oleksandr Tsyhanenko ◽  
Olena Taranenko ◽  
Vadym Kryzhevskyi ◽  
Borys Mankovskyi
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
International Research ◽  
Family Income ◽  
Key Words Diabetes Mellitus ◽  
Key Words Diabetes ◽  
Type 2 Dm

The results of prospective international research for risk factors determining of depression and assessing their impact on life in patients with type 2 Diabetes Mellitus (DM) were described in this article. Aims: To study risk factors of depression in patients with type 2 DM, based on results of conduc ted research. Materials and me thods: accor ding to study requi rements of international research INTERPRET-DD (International Prevalence and Treat ment of Diabetes and Depres sion), 190 pa tients diff erent sex were rando mized. Adapted scales PHQ-9, PAID, WHO, MINI-6, Hamilton Score were used as materials for depression diagnostic; processed data from patients Medical History for the last 15 years, anamnesis, physical examination, consulting by psychiatrist, endocrinologist, podiatrist, HbA1C and Lipid profi le measu ring. The work consisted of tandem collaboration between a psychiat rist and an endocrinologist, who monitored randomized patients for one year, and also determined the tactics of diagnosis, treatment, and the development of preventive measures. According to received results, the follow risk factors of depression in patients with type 2 DM were frequent episodes of hypohyperglycemia, high level of concomitant diseases in anamnesis, patient’s age, low education level, job absence, unstable family income, family status, presence of depression in family anamnesis. Key words: diabetes mellitus, depression, depression factors, antidepressant

Serum Ferritin Status of Patients with Type 2 DM Attending OPD of BIRDEM General Hospital

2020 ◽  
Vol 11 (1) ◽  
pp. 7-10
Author(s):  
Khadiza Begum ◽  
Fahmida Islam ◽  
Farjana Aktar ◽  
Murshida Aziz ◽  
Tohfa E Ayub Tahiya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Serum Ferritin ◽  
Study Groups ◽  
Acute Phase Reactant ◽  
The Body ◽  
Iron Stores ◽  
Normal Healthy Individual ◽  
Diabetes Patients

Background: In recent times much is talked about of serum ferritin, an acute phase reactant a marker of iron stores in the body and its association with diabetes mellitus. Studies implicate that increased body iron stores and subclinical hemochromatosis has been associated with the development of glucose intolerance, type 2 diabetes and its micro as well as macrovascular complications. Material & Methods: This study was carried out to examine and to observe for any relationship between serum ferritin with Type 2 diabetes mellitus. Our study populations were included 163. Among them 81 type 2 diabetes patients as a case (M=49,F=32, mean 44.68 age in years)and 82 normal healthy individual as a control ( M=35, F=47 , mean 34.71 in years). Results: Majority were healthy outpatients who had come for regular checkup and were matched with controls. Serum ferritin and FBS were estimated and other investigations. Results showed that although Serum ferritin was in the normal range value it was increased in type 2 diabetes patients than in controls and was statistically significant, we did get a positive correlation with duration of diabetes. It can be concluded that there were positive associations between serum ferritin and FBG, age, sex among study groups. Conclusion: In conclusion our study shows that there is significant correlation between increased serum ferritin in diabetes compared to individuals with normal blood sugars in this part and hyper ferritinemia may be one of the causes for development of insulin resistance before overt diabetes. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 7-10

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