Faculty Opinions recommendation of Vitamin D deficiency and depression in adults: systematic review and meta-analysis.

Author(s):  
John Eisman
2021 ◽  
Vol 40 (1) ◽  
Author(s):  
Angeline Jeyakumar ◽  
Vidhya Shinde ◽  
Reshma Ravindran

Abstract Background Vitamin D deficiency among pregnant women is a public health concern globally. In India, individual studies report high prevalence. However, lack of national data masks the true burden. This work determined the pooled prevalence of vitamin D deficiency among pregnant women in India through a systematic review of literature and meta-analysis. Methods Three different search engines yielded 15 eligible articles. Study quality was assessed by 10 different criteria and summary of study quality was categorized as per Cochrane standards. Meta-analysis was performed to estimate pooled prevalence of vitamin D deficiency among healthy pregnant women and heterogeneity among selected studies. A sample of n = 4088 was used to study the pooled prevalence among pregnant women. Results The random effects combined estimate was 32.35% (95% CI, (12.58–117.48). High heterogeneity (tau2 = 0.39, I2 = 100%) and high risk of bias was observed among the selected studies. The test for overall effect was observed to be z = 2.54(P = 0.01). Conclusion Pooled estimate > 30% emphasizes the need for screening through antenatal care services and initiate preventive measures to address the deficiency.


2021 ◽  
Vol 32 (6) ◽  
pp. 508-518
Author(s):  
Shanzhen Shi ◽  
◽  
Jiaxing Feng ◽  
Lixiang Zhou ◽  
Yu Li ◽  
...  

2013 ◽  
Vol 202 (2) ◽  
pp. 100-107 ◽  
Author(s):  
Rebecca E. S. Anglin ◽  
Zainab Samaan ◽  
Stephen D. Walter ◽  
Sarah D. McDonald

BackgroundThere is conflicting evidence about the relationship between vitamin D deficiency and depression, and a systematic assessment of the literature has not been available.AimsTo determine the relationship, if any, between vitamin D deficiency and depression.MethodA systematic review and meta-analysis of observational studies and randomised controlled trials was conducted.ResultsOne case-control study, ten cross-sectional studies and three cohort studies with a total of 31 424 participants were analysed. Lower vitamin D levels were found in people with depression compared with controls (SMD = 0.60,95% Cl 0.23–0.97) and there was an increased odds ratio of depression for the lowest v. highest vitamin D categories in the cross-sectional studies (OR = 1.31, 95% CI 1.0–1.71). The cohort studies showed a significantly increased hazard ratio of depression for the lowest v. highest vitamin D categories (HR=2.21, 95% CI 1.40–3.49).ConclusionsOur analyses are consistent with the hypothesis that low vitamin D concentration is associated with depression, and highlight the need for randomised controlled trials of vitamin D for the prevention and treatment of depression to determine whether this association is causal.


2018 ◽  
Vol 24 (4) ◽  
pp. 269-278 ◽  
Author(s):  
Salam Vatandost ◽  
Marzieh Jahani ◽  
Ali Afshari ◽  
Mohammad Reza Amiri ◽  
Rashid Heidarimoghadam ◽  
...  

Background: The prevalence of vitamin D deficiency in the Iranian community is very high. Women and older people are at the higher risk of vitamin D deficiency. Aim: This study aimed to estimate the prevalence of vitamin D deficiency in Iran by combining the results of various studies. Methods: This was a systematic review and meta-analysis. Separate strategies were developed for search in national databases (Irandoc, Magiran, SID) and international databases (Web of Science, PubMed, and Scopus) using the keywords of “vitamin D deficiency,” “Iran,” and “prevalence.” The titles and abstracts of the articles were screened and related full texts were appraised. Those articles that met inclusion criteria were selected for meta-analysis. The heterogeneity of the articles was assessed via the Chi-square test. They were combined using the random-effect approach. In addition, the groups were categorized and analyzed in terms of age and gender. Results: Of 639 articles, 30 articles with a sample size of 26,042 people were included for data analysis. The overall prevalence of vitamin D deficiency was reported as 0.56. Subgroup analysis showed that 0.64 of women and 0.44 of men were suffering from vitamin D deficiency. The prevalence of vitamin D deficiency in the age groups under 20, 20–50, and over 50 years was 0.56.4, 0.72.4, and 0.59.8, respectively. Conclusions: The Iranian Ministry of Health is expected to design strategies to improve the status of vitamin D at the national level.


Author(s):  
Marcos Pereira ◽  
Alialdo Dantas Damascena ◽  
Laylla Mirella Galvão Azevedo ◽  
Tarcio de Almeida Oliveira ◽  
Jerusa da Mota Santana

2018 ◽  
Vol 9 ◽  
Author(s):  
Mansour Amraei ◽  
Safoura Mohamadpour ◽  
Kourosh Sayehmiri ◽  
Seyedeh Fatemeh Mousavi ◽  
Ehsan Shirzadpour ◽  
...  

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