Faculty Opinions recommendation of Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study.

Author(s):  
Rachel Kacmar
Author(s):  
Waraporn Thepampan ◽  
Nuchsara Eungapithum ◽  
Krittai Tanasombatkul ◽  
Phichayut Phinyo

Postpartum hemorrhage (PPH) is a common complication of pregnancy and a global public health concern. Even though PPH risk factors were extensively studied and reported in literature, almost all studies were conducted in non-Asian countries or tertiary care centers. Our study aimed to explore relevant risk factors for PPH among pregnant women who underwent transvaginal delivery at a Thai–Myanmar border community hospital in Northern Thailand. An exploratory nested case-control study was conducted to explore risk factors for PPH. Women who delivered transvaginal births at Maesai hospital from 2014 to 2018 were included. Two PPH definitions were used, which were ≥ 500 mL and 1000 mL of estimated blood loss within 24 h after delivery. Multivariable conditional logistic regression was used to identify significant risk factors for PPH and severe PPH. Of 4774 women with vaginal births, there were 265 (5.55%) PPH cases. Eight factors were identified as independent predictors for PPH and severe PPH: elderly pregnancy, minority groups, nulliparous, previous PPH history, BMI ≥ 35 kg/m2, requiring manual removal of placenta, labor augmentation, and fetal weight > 4000 gm. Apart from clinical factors, particular attention should be given to pregnant women who were minority groups as PPH risk significantly increased in this population.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
N Tiwana ◽  
A Pietronigro ◽  
M Mosillo ◽  
N Principi ◽  
D Carnevali ◽  
...  

Abstract Background Falls and fall-related injuries are a major public health issue which needs global attention due to its clinical and socioeconomic impact. Inpatient falls are the most common adverse event in hospital. Important risk factors for falls are polypharmacy and the assumption of so-called Fall Risk Increasing Drugs (FRIDs). Aims of our study were to investigate the associations between falls and the use of medications among inpatients by conducting a retrospective case-control study in a rehabilitation hospital in Northern Italy in 2018. Methods Three unique control for each faller, matched by age, sex and hospitalization ward, were selected. A Conditional Logistic Regression was performed to analyze the impact that 13 types of FRIDs individually and the number of administrated FRIDs had on the risk of falling. A second regression model was obtained adjusting the case-control matching for CIRS, Morse and Barthel scores. Results We identified 148 cases and 444 controls. 3 types of FRIDs were significantly correlated (p < 0,05) with an increased risk of falling: Antipsychotics [OR:1,98;CI 95%:1,01-3,89], Antidepressants [OR:2,18;CI 95%:1,32-3,59], Diuretics [OR:1,71;CI 95%:1,09-2,68]. Antidepressants were the only type of FRID significantly correlated (p = 0,008) even in the model adjusted for CIRS, Morse and Barthel scores [OR:2,00;CI 95%:1,20-3,34]. The unadjusted model showed that the addition of one type of FRID to therapy was significantly associated with the fall event (p < 0.05) [OR:1.21;CI 95%: 1.05 - 1.40]. Conclusions Assumption of drugs and polypharmacy could play a role in hospital falling. Recently developed fall risk assessment tools suffer from low specificity and sensitivity and do not assess these risk factors. A holistic approach with a multidimensional evaluation of the patient through screening tools, functional assessment tools and a full medical evaluation should be improved. Key messages Drugs may represent an important variable in determining the risk of falls in hospitalized patients, but they should not be considered alone. Screening tools for fall risk should take into account polypharmacy such as other intrinsic and extrinsic risk factors within an holistic approach.


2018 ◽  
Vol 21 (02) ◽  
pp. 347-353
Author(s):  
Manzoor Ahmad Naeem ◽  
Usra Naeem ◽  
Asif Hanif

Introduction: Pregnancy is a normal physiological event but some pregnancyspecific or other medical conditions can cause maternal as well as fetal morbidities and evenmortalities. Among them, raised blood pressure during pregnancy adversely affects bothmaternal and fetal outcomes. Objectives: In this study, risk factors associated with hypertensivedisorders of pregnancy are explored and pregnancy outcomes of hypertensive women withnormotensive pregnant women are compared. Design: Case control study. Settings: Obstetricsand gynecology department of Jinnah hospital Lahore. Period: 1st October 2011 to 24 February2012. Subjects and methods: The case control study of 250 cases (pregnant females withhypertensive disorders) and controls (pregnant females without hypertensive disorder),presented at obstetrics & gynecology department of Jinnah hospital during 1st October 2011 to24 February 2012 was conducted. SPSS software (16) and MS excel were used for statisticalanalysis. Results: Mean age for cases and controls was 26.96 ± 5.29yearsand 25.25 ±4.60years, respectively. Age and history of pregnancy was found to be significantly associatedwith hypertensive disorders of pregnancy. Comparison of neonatal outcome between casegroup and control group showed that hypertensive pregnant women were at higher risk of havingadverse pregnancy outcome. Conclusions: Women with hypertension during pregnancy are atincreased risk of having adverse pregnancy outcome as compared to normotensive women andage, history of pregnancy induced hypertension are contributing risk factors for developinghypertension during pregnancy.


Author(s):  
Sunny Ohlan ◽  
S. K. Jha ◽  
Parul Singhal

Background: Anaemia in pregnancy (AIP) is one of the most common preventable causes of maternal morbidity and poor prenatal outcome. World Health Organization (WHO) has accepted up to 11 gm/dl as the normal hemoglobin (Hb) level in pregnancy. In Haryana state, the prevalence of anaemia among pregnant women is 50.2% in urban areas and 58.1% in rural areas. Pregnant women are predominantly susceptible to nutritional deficiencies because of the increased metabolic demands imposed by pregnancy and its related factors. The aim and objective of the study was to determine the behavioural factors associated with anaemia among pregnant women delivering at a tertiary care hospital in Haryana.Methods: This hospital-based case control study was carried out in BPS Government Medical College for Women, Khanpur Kalan, Sonipat (Haryana). Study was conducted for one year. One hundred sixty-eight pregnant women were enrolled for study. Inclusion criteria for cases and controls was age of 18 years and above and residents of Sonepat district. Analysis was performed by using R statistical software.Results: The majority 57 (67.9%) of cases and 49 (58.3%) of controls were in age group of 18-24 years. Among different behavioral risk factors studied, not using bed nets, not wearing shoes consistently, eating pica and no use of the other drugs during pregnancy were significantly associated with anemia during pregnancy. However, on Multivariable Logistic regression analysis, the major behavioral risk factors for anemia were not using bed net during pregnancy (AOR: 1.83, 95% CI: 0.68-5.01), and not wearing shoes consistently during pregnancy (AOR: 2.77, 95% CI: 0.83-10.01). The odds of getting anaemia in pregnant mothers who reported pica during their pregnancy was AOR = 2.85 (CI: 0.90 – 10.01) than odds of mothers who did not report pica during their pregnancy.Conclusions: Consistent use of bed net, wearing shoes and not consuming pica prevent anaemia during pregnancy. 


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