Methods for Transition Toward Computer Assisted Cognitive Examination

2015 ◽  
Vol 54 (03) ◽  
pp. 256-261
Author(s):  
S. Valenzi ◽  
Z. R. Struzik ◽  
A. Cichocki ◽  
P. Jurica
Keyword(s):  
Cognitive Impairment ◽  
Open Source ◽  
Modern Technology ◽  
Screening Tests ◽  
Computer Assisted ◽  
Clinical Settings ◽  
Cognitive Tests ◽  
Technological Advances ◽  
The Common ◽  
State Examination

SummaryIntroduction: We present a software framework which enables the extension of current methods for the assessment of cognitive fitness using recent technological advances.Background: Screening for cognitive impairment is becoming more important as the world’s population grows older. Current methods could be enhanced by use of computers. Introduction of new methods to clinics requires basic tools for collection and communication of collected data.Objectives: To develop tools that, with minimal interference, offer new opportunities for the enhancement of the current interview based cognitive examinations.Methods: We suggest methods and discuss process by which established cognitive tests can be adapted for data collection through digitization by pen enabled tablets. We discuss a number of methods for evaluation of collected data, which promise to increase the resolution and objectivity of the common scoring strategy based on visual inspection. By involving computers in the roles of both instructing and scoring, we aim to increase the precision and reproducibility of cognitive examination.Results: The tools provided in Python framework CogExTools available at http://bsp.brain.riken.jp/cogextools/ enable the design, application and evaluation of screening tests for assessment of cognitive impairment. The toolbox is a research platform; it represents a foundation for further collaborative development by the wider research community and enthusiasts. It is free to download and use, and open-source.Conclusion: We introduce a set of open-source tools that facilitate the design and development of new cognitive tests for modern technology. We provide these tools in order to enable the adaptation of technology for cognitive examination in clinical settings. The tools provide the first step in a possible transition toward standardized mental state examination using computers.

scholarly journals Cognitive Impairment in People with Diabetes-Related Foot Ulceration

2021 ◽  
Vol 10 (13) ◽  
pp. 2808
Author(s):  
Ranita Siru ◽  
Melanie S. Burkhardt ◽  
Wendy A. Davis ◽  
Jonathan Hiew ◽  
Laurens Manning ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cognitive Impairment ◽  
Sex Education ◽  
Foot Ulcer ◽  
Screening Tests ◽  
Community Settings ◽  
Foot Ulceration ◽  
Complex Diabetes ◽  
State Examination

Aims: To determine whether there is an excess of cognitive impairment in patients with type 2 diabetes and foot ulceration. Methods: 55 patients with type 2 diabetes and foot ulcers attending Multidisciplinary Diabetes Foot Ulcer clinics (MDFU cohort) were compared with 56 patients with type 2 diabetes attending Complex Diabetes clinics (CDC cohort) using commonly used screening tests for cognitive impairment (Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MOCA)), as well as foot self-care, mood and health literacy. MMSE was also compared between the MDFU cohort and a historical community-based cohort of patients with type 2 diabetes (FDS2 cohort). Results: Median MMSE scores were the same in all three groups (28/30). Median MOCA scores did not differ between the MDFU and CDC cohorts (25/30). There were no significant differences in the percentages of patients with MMSE ≤ 24 or MOCA ≤ 25 between MDFU and CDC cohorts (3.6% versus 10.7%, p = 0.27 and 56.4% versus 51.8%, p = 0.71, respectively), findings that did not change after adjustment for age, sex, education, diabetes duration, and random blood glucose. Conclusions: Using conventionally applied instruments, patients with type 2 diabetes and foot ulceration have similar cognition compared with patients without, from either hospital-based clinic or community settings.

scholarly journals Detection of mild cognitive impairment in middle-aged and older adults with obstructive sleep apnoea

2018 ◽  
Vol 52 (5) ◽  
pp. 1801137 ◽  
Author(s):  
Katia Gagnon ◽  
Andrée-Ann Baril ◽  
Jacques Montplaisir ◽  
Julie Carrier ◽  
Sirin Chami ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Obstructive Sleep Apnoea ◽  
Mental State ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Sleep Apnoea ◽  
Screening Tests ◽  
Obstructive Sleep ◽  
State Examination

Obstructive sleep apnoea increases the risk for mild cognitive impairment and dementia. The present study aimed to characterise the ability of two cognitive screening tests, the Mini-Mental State Examination and the Montreal Cognitive Assessment, to detect mild cognitive impairment in adults aged 55–85 years with and without obstructive sleep apnoea.We included 42 subjects with mild and 67 subjects with moderate-to-severe obstructive sleep apnoea. We compared them to 22 control subjects. Mild cognitive impairment was diagnosed by a comprehensive neuropsychological assessment. We used receiver operating characteristic curves to assess the ability of the two screening tests to detect mild cognitive impairment.The two screening tests showed similar discriminative ability in control subjects. However, among the mild and the moderate-to-severe obstructive sleep apnoea groups, the Mini-Mental State Examination was not able to correctly identify subjects with mild cognitive impairment. The Montreal Cognitive Assessment's discriminant ability was acceptable in both sleep apnoea groups and was comparable to what was observed in controls.The Mini-Mental State Examination should not be used to screen for cognitive impairment in patients with obstructive sleep apnoea. The Montreal Cognitive Assessment could be used in clinical settings. However, clinicians should refer patients for neuropsychological assessment when neurodegenerative processes are suspected.

scholarly journals Montreal Cognitive Assessment scale in patients with Parkinson Disease with normal scores in the Mini-Mental State Examination

2019 ◽  
Vol 13 (1) ◽  
pp. 78-81 ◽  
Author(s):  
Krisly Arguedas Vásquez ◽  
Erick Miranda Valverde ◽  
Daniel Valerio Aguilar ◽  
Henri-Jacques Hernández Gabarain
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mental State ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Montreal Cognitive Assessment ◽  
Screening Tests ◽  
Study Results ◽  
State Examination

ABSTRACT. Several screening tests have been used for cognitive evaluation in Parkinson’s disease (PD). Objective: To evaluate the usefulness of the Montreal Cognitive Assessment (MoCA) in patients with Parkinson’s disease and no cognitive impairment complaints. Methods: A total of 40 PD patients with no complaints of cognitive problems were included. Patients were selected using the Mini-Mental State Examination (MMSE) and the MoCA was then administered. Results: 80% of patients exhibited Mild Cognitive Impairment (MCI) according to the MoCA. Statistically significant differences in visuospatial, attention and delayed recall functions were evident between the normal and abnormal MoCA groups. Conclusion: The study results suggest that MoCA may be a good screening test in patients with PD who do not present cognitive complaints.

scholarly journals Brief cognitive tests validated in Peru for detection of cognitive impairment A systematic mapping of the scientific literature

2020 ◽  
Vol 14 (2) ◽  
pp. 134-144
Author(s):  
Nilton Custodio ◽  
Eder Herrera-Pérez ◽  
Rosa Montesinos ◽  
David Lira ◽  
Tatiana Metcalf
Keyword(s):  
Cognitive Impairment ◽  
Good Choice ◽  
Superior Performance ◽  
Screening Tests ◽  
Cognitive Tests ◽  
Systematic Mapping ◽  
Eligibility Criteria ◽  
Library Network ◽  
Reference Databases ◽  
Mapping Techniques

Abstract. Brief cognitive tests (BCTs) are necessary for early detection of cognitive impairment, particularly in primary care settings. Objective: This report describes a systematic review of BCTs evaluated in Peruvian populations. Methods: We used systematic mapping techniques to identify articles on screening tests for cognitive impairment involving Peruvian subjects. We included studies published in English and Spanish up to 2018. We reviewed 6 reference databases within the Virtual Health Library network, as well as the Web of Science, Scopus (MEDLINE), and EMBASE databases. Results: Ten out of 447 articles met the inclusion criteria. Studies included both outpatient (9) and community-based (2) samples. Eligibility criteria of the studies were similar. Although different protocols were applied, the diagnostic criteria were standardized. For discrimination between dementia and controls, IFS (AUC: 0.99) and ACE (AUC: 0.95 to 1.00) showed superior performance, as did the M@T (AUC: 1.00) and CDT-Mv (AUC: 0.94 to 1.00) for discriminating between Alzheimer’s disease (AD) and controls. Conclusion: The available evidence is limited. However, our analysis of national data suggests that the ACE may be a good choice whenever it can be applied to Peruvian patients. Alternatively, the M@T and IFS can be used for screening patients with suspected AD or FTD, respectively.

scholarly journals The Montreal Cognitive Assessment (MoCA-Ina) versus the Mini-Mental State Examination (MMSE-Ina) For Detecting Mild Cognitive Impairment among The Elderly

2021 ◽  
Vol 20 (1) ◽  
pp. 164-169
Author(s):  
Ida Untari ◽  
Achmad Arman Subijanto ◽  
Diah Kurnia Mirawati ◽  
Rossi Sanusi
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Medical Science ◽  
The Elderly ◽  
Rank Test ◽  
Cognitive Tests ◽  
Level Of Education ◽  
And Gender ◽  
State Examination

Background: There are many neuropsychological instruments are used for screening cognitivefunctions in adults, with or without health problems such asthe MMSE-Ina and MoCA-Ina. Objectives:This study was designed to test the correlations and differences between MMSE-Inaand MoCA-Ina for early detection of decreasing cognitive function in the elderly. Methods: Total278 subjects were randomly selected from the 17 sub dictricts of Surakarta Municipality, CentralJava, Indonesia. Data collection was carried out in December 2018 and January 2019, withallsubjects individually interviewed using two cognitive tests (which lasted 30 – 45 minutes) alongwith physical and neurological examinations. The MMSE-Ina and MoCA-Ina scores of eachparticipant were correlated using the non-parametric Spearman rank test. Both scores werecompared based on level of education and gender. Results: The MoCa-Ina detected using MCIwas 215 (77.3%) while MMSE-Ina was 189 (68%), with 176 (63.3%) in severe 10 (3.5%).This study also showed a strong correlation between the MMSE-Ina and MoCA-Ina scores (r= 0.633 p < 0.000). The cut pointin this study were 23/24 for the MMSE-Ina and 25/26 for theMoCA-Ina which was less than 23 and 25,indicated cognitive impairment. Conclusion: TheMoCA-Ina is usedto screen cognitive impairment in the elderly. Bangladesh Journal of Medical Science Vol.20(1) 2021 p.164-169

scholarly journals Mild cognitive impairment: cognitive screening or neuropsychological assessment?

2008 ◽  
Vol 30 (4) ◽  
pp. 316-321 ◽  
Author(s):  
Breno Satler Diniz ◽  
Paula Villela Nunes ◽  
Monica S Yassuda ◽  
Fernanda S Pereira ◽  
Mariana K Flaks ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Clinical Practice ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Assessment ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Screening Tests ◽  
Neuropsychological Profile ◽  
State Examination ◽  
Multiple Domain

OBJECTIVE: To describe the neuropsychological profile of mild cognitive impairment subtypes (amnestic, non-amnestic and multiple-domain) of a clinical sample. We further address the diagnostic properties of the Mini-Mental State Examination and the Cambridge Cognitive Examination for the identification of the different mild cognitive impairment subtypes in clinical practice. METHOD: Cross-sectional clinical and neuropsychological evaluation of 249 elderly patients attending a memory clinic at a university hospital in Sao Paulo, Brazil. RESULTS: The performance of patients with mild cognitive impairment was heterogeneous across the different subtests of the neuropsychological battery, with a trend towards an overall worse performance for amnestic (particularly multiple domain) mild cognitive impairment as compared to non-amnestic subtypes. Screening tests for dementia (Mini-Mental State Examination and Cambridge Cognitive Examination) adequately discriminated cases of mild Alzheimer's disease from controls, but they were not accurate to discriminate patients with mild cognitive impairment (all subtypes) from control subjects. CONCLUSIONS: The discrimination of mild cognitive impairment subtypes was possible only with the aid of a comprehensive neuropsychological assessment. It is necessary to develop new strategies for mild cognitive impairment screening in clinical practice.

scholarly journals Norms and equivalences for MoCA-30, MoCA-22, and MMSE in the oldest-old

2021 ◽  
Author(s):  
Zarui A. Melikyan ◽  
Michael Malek-Ahmadi ◽  
Kathleen O’Connor ◽  
Alireza Atri ◽  
Claudia H. Kawas ◽  
...  
Keyword(s):  
Healthy Aging ◽  
Oldest Old ◽  
Screening Tests ◽  
Cognitive Tests ◽  
Cognitive Screening ◽  
Maximum Score ◽  
Cognitive Domains ◽  
Linear Smoothing ◽  
Log Linear ◽  
State Examination

Abstract Background Cognitive screening is important for the oldest-old (age 90 +). This age group is the fastest growing and has the highest risk of dementia. However, norms and score equivalence for screening tests are lacking for this group. Aims To provide norms and score equivalence for commonly used cognitive screening tests for the oldest-old. Methods Data on 157 participants of the Center for Healthy Aging Longevity Study aged 90 + were analyzed. First, we derived norms for (1) subtests and cognitive domains of the in-person Montreal Cognitive Assessment having a maximum score of 30 (MoCA-30) and (2) the total MoCA-22 score, obtained from the in-person MoCA-30 by summing the subtests that do not require visual input to a maximum score of 22. These norms were derived from 124 participants with a Mini-Mental State Examination (MMSE) ≥ 27. Second, we derived score equivalences for MMSE to MoCA-30 and MoCA-22, and MoCA-30 to MoCA-22 using equipercentile equating method with log-linear smoothing, based on all 157 participants. Results MoCA-22 total score norms are: mean = 18.3(standard deviation = 2.2). An MMSE score of 27 is equivalent to a MoCA-30 score of 22 and a MoCA-22 score of 16. Discussion and conclusions Subtest, domain and MoCA-22 norms will aid in evaluation of the oldest-old who cannot complete the MoCA-30 or are tested over the phone. The equivalences of the three cognitive tests (MMSE, MoCA-30, MoCA-22) in the oldest-old will facilitate continuity of cognitive tracking of individuals tested with different tests over time and comparison of the studies that use different cognitive tests.

scholarly journals Longitudinal Changes in Performance on Cognitive Screening Tests in Patients with Mild Cognitive Impairment and Alzheimer Disease

2017 ◽  
Vol 7 (3) ◽  
pp. 366-373 ◽  
Author(s):  
Fangzhou Li ◽  
Hajime Takechi ◽  
Atsuko Kokuryu ◽  
Ryosuke Takahashi
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Test Performance ◽  
Screening Tests ◽  
Cognitive Screening ◽  
Word Fluency ◽  
Longitudinal Changes ◽  
Picture Memory ◽  
State Examination

Background: Neuropsychological tests that can track changes in cognitive functions after diagnosis of Alzheimer disease (AD) and mild cognitive impairment (MCI), including episodic memory, should be further developed. Methods: The participants of our study consisted of 22 mild AD patients and 11 MCI patients. They were followed up for 2 years. Brief cognitive screening tests were administered to the participants. Longitudinal changes in test performance were evaluated and analyzed. Results: In this longitudinal study, the Scenery Picture Memory Test (SPMT) showed significant changes over 2 years in both MCI and AD participants. The Mini-Mental State Examination (MMSE) and Word Fluency Test-vegetable showed significant changes only in AD participants. Other tests all showed little or no decline in results. Conclusions: The SPMT can be a useful tool for effectively observing changes during follow-up of MCI and AD patients.

High-resolution measurement of birefringent fine structure in living cells using a new polarized light microscope

1995 ◽  
Vol 53 ◽  
pp. 54-55
Author(s):  
Rudolf Oldenbourg
Keyword(s):  
Light Microscope ◽  
Fluorescent Dyes ◽  
Polarized Light ◽  
Processing System ◽  
Video Camera ◽  
Molecular Organization ◽  
Computer Assisted ◽  
Image Recording ◽  
Birefringent Crystal ◽  
Technological Advances

The recent renaissance of the light microsope is fueled in part by technological advances in components on the periphery of the microscope, such as the laser as illumination source, electronic image recording (video), computer assisted image analysis and the biochemistry of fluorescent dyes for labeling specimens. After great progress in these peripheral parts, it seems timely to examine the optics itself and ask how progress in the periphery facilitates the use of new optical components and of new optical designs inside the microscope. Some results of this fruitful reflection are presented in this symposium.We have considered the polarized light microscope, and developed a design that replaces the traditional compensator, typically a birefringent crystal plate, with a precision universal compensator made of two liquid crystal variable retarders. A video camera and digital image processing system provide fast measurements of specimen anisotropy (retardance magnitude and azimuth) at ALL POINTS of the image forming the field of view. The images document fine structural and molecular organization within a thin optical section of the specimen.

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