A Study on the N-methylformamide Excretion Rate of Workers at Synthetic Leather Factories in Korea

SummaryVarious renal imaging agents that were reported in the past and a new agent, 99mTc-malate as well as 99mTc-cystein acetazolamide complex were prepared using electrolysis and electrochemical methods. These were studied for their labelling efficiency. After animal experiments with selected 99mTc-com- pounds, 99mTc-rnalate proved to be sufficient for renal imaging with adequate concentration. 99mTcmalate differs from other renal imaging agents in the utilization of endogeneous metabolic product.The first half time of 99mTc-malate in humans is 17 minutes, on the average, and the urinary excretion rate of 99mTc-malate is 36±6.05% in 1 hour after intravenous administration, 44 ± 3.41% in 2 hours and 50 + 5.62% in 3 hours.In our 40 clinical experiences of 99m-Tc-rnalate, most cases demonstrated quite clear renal images in the serial scintiphotos except cases whose serum creatinines were over 4.5 mg/dl.

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Low-dose dopamine infusion, renal haemodynamics and urinary albumin excretion rate in insulin-dependent diabetics and in normal man

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365518809085790 ◽

1988 ◽

Vol 48 (7) ◽

pp. 679-683 ◽

Cited By ~ 6

Author(s):

J. S. Christiansen ◽

M. M. Pedersen ◽

A. Schmitz ◽

C. K. Christensen ◽

T. Christensen ◽

...

Keyword(s):

Low Dose ◽

Urinary Albumin Excretion ◽

Excretion Rate ◽

Albumin Excretion Rate ◽

Urinary Albumin ◽

Urinary Albumin Excretion Rate ◽

Dopamine Infusion ◽

Albumin Excretion ◽

Insulin Dependent ◽

Normal Man

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Different diuresis-dependent excretions of urinary enzymes: N-acetyl-beta-D-glucosaminidase, alanine aminopeptidase, alkaline phosphatase, and gamma-glutamyltransferase.

Clinical Chemistry ◽

10.1093/clinchem/32.3.529 ◽

1986 ◽

Vol 32 (3) ◽

pp. 529-532 ◽

Cited By ~ 27

Author(s):

K Jung ◽

G Schulze ◽

C Reinholdt

Keyword(s):

Alkaline Phosphatase ◽

Brush Border ◽

Excretion Rate ◽

Urine Flow ◽

High Intake ◽

Brush Border Enzymes ◽

Urinary Creatinine ◽

Gamma Glutamyltransferase ◽

Alanine Aminopeptidase ◽

Brush Border Enzyme

Abstract We studied how much of the lysosomal enzyme N-acetyl-beta-D-glucosaminidase (EC 3.2.1.30) and of the brush-border enzymes alanine aminopeptidase (EC 3.4.11.2), alkaline phosphatase (EC 3.1.3.1), and gamma-glutamyltransferase (EC 2.3.2.2) was excreted in urine over 8 h after a high intake of fluid (22 mL per kilogram of body weight). The hourly excretion of all four enzymes increased with the increasing urine flow rate. The excretion rate of the brush-border enzymes was more markedly influenced than that of N-acetyl-beta-D-glucosaminidase. By relating the enzyme excretion to urinary creatinine we could reduce the variability of brush-border enzyme output and could completely compensate for the effect of diuresis on the excretion of N-acetyl-beta-D-glucosaminidase.

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Whole-body arginine dimethylation is associated with all-cause mortality in adult renal transplant recipients

Amino Acids ◽

10.1007/s00726-021-02965-1 ◽

2021 ◽

Author(s):

Adrian Post ◽

Alexander Bollenbach ◽

Stephan J. L. Bakker ◽

Dimitrios Tsikas

Keyword(s):

Renal Transplant ◽

Excretion Rate ◽

Whole Body ◽

Renal Transplant Recipients ◽

Transplant Recipients ◽

Kidney Donors ◽

Body Protein ◽

All Cause Mortality ◽

Arginine Residues ◽

Excretion Rates

AbstractArginine residues in proteins can be singly or doubly methylated post-translationally. Proteolysis of arginine-methylated proteins provides monomethyl arginine, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA). ADMA and SDMA are considered cardiovascular risk factors, with the underlying mechanisms being not yet fully understood. SDMA lacks appreciable metabolism and is almost completely eliminated by the kidney, whereas ADMA is extensively metabolized to dimethylamine (DMA), with a minor ADMA fraction of about 10% being excreted unchanged in the urine. Urinary DMA and ADMA are useful measures of whole-body asymmetric arginine-dimethylation, while urinary SDMA serves as a whole-body measure of symmetric arginine-dimethylation. In renal transplant recipients (RTR), we previously found that higher plasma ADMA concentrations and lower urinary ADMA and SDMA concentrations were associated with a higher risk of all-cause mortality. Yet, in this RTR collective, no data were available for urinary DMA. For the present study, we additionally measured the excretion rate of DMA in 24-h collected urine samples of the RTR and of healthy kidney donors in the cohort, with the aim to quantitate whole-body asymmetric (ADMA, DMA) and symmetric (SDMA) arginine-dimethylation. We found that lower DMA excretion rates were associated with higher all-cause mortality, yet not with cardiovascular mortality. In the healthy donors, kidney donation was associated with considerable decreases in ADMA (by − 39%, P < 0.0001) and SDMA (by − 21%, P < 0.0001) excretion rates, yet there was no significant change in DMA (by − 9%, P = 0.226) excretion rate. Our results suggest that protein-arginine dimethylation is altered in RTR compared to healthy kidney donors and that it is pronouncedly shifted from symmetric to asymmetric arginine-dimethylation, with whole-body protein-arginine dimethylation being almost unaffected.

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Body Surface Area, Creatinine Excretion Rate, and Total Body Water: Reference Data for Adults in the United States

Kidney Medicine ◽

10.1016/j.xkme.2020.10.009 ◽

2021 ◽

Author(s):

Florian Buchkremer ◽

Stephan Segerer

Keyword(s):

United States ◽

Surface Area ◽

Body Surface ◽

Total Body Water ◽

Reference Data ◽

Excretion Rate ◽

The United States ◽

Creatinine Excretion ◽

Total Body ◽

Creatinine Excretion Rate

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Preparation of Flame-Retardant Polyurethane and Its Applications in the Leather Industry

Polymers ◽

10.3390/polym13111730 ◽

2021 ◽

Vol 13 (11) ◽

pp. 1730

Author(s):

Shaolin Lu ◽

Yechang Feng ◽

Peikun Zhang ◽

Wei Hong ◽

Yi Chen ◽

...

Keyword(s):

Flame Retardant ◽

Environmentally Friendly ◽

Current Status ◽

Leather Industry ◽

Synthetic Leather ◽

Overall Performance ◽

Reactive Flame Retardant

As a novel polymer, polyurethane (PU) has been widely applied in leather, synthetic leather, and textiles due to its excellent overall performance. Nevertheless, conventional PU is flammable and its combustion is accompanied by severe melting and dripping, which then generates hazardous fumes and gases. This defect limits PU applications in various fields, including the leather industry. Hence, the development of environmentally friendly, flame-retardant PU is of great significance both theoretically and practically. Currently, phosphorus-nitrogen (P-N) reactive flame-retardant is a hot topic in the field of flame-retardant PU. Based on this, the preparation and flame-retardant mechanism of flame-retardant PU, as well as the current status of flame-retardant PU in the leather industry were reviewed.

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Studies on Synthetic Leather Sheet of Polyamide

Kobunshi Kagaku ◽

10.1295/koron1944.24.582 ◽

1967 ◽

Vol 24 (269) ◽

pp. 582-591

Author(s):

Wakuo Matsumura ◽

Takeshi Mashimo ◽

Mutsuo Kuga

Keyword(s):

Synthetic Leather

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Variability of Urinary Creatinine in Healthy Individuals

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18063166 ◽

2021 ◽

Vol 18 (6) ◽

pp. 3166

Author(s):

Gerd Sallsten ◽

Lars Barregard

Keyword(s):

Flow Rate ◽

Excretion Rate ◽

Time Of Day ◽

Urinary Flow Rate ◽

Urinary Flow ◽

Diurnal Variability ◽

Creatinine Excretion ◽

Blood Samples ◽

Urinary Creatinine ◽

Creatinine Excretion Rate

Many urinary biomarkers are adjusted for dilution using creatinine or specific gravity. The aim was to evaluate the variability of creatinine excretion, in 24 h and spot samples, and to describe an openly available variability biobank. Urine and blood samples were collected from 60 healthy non-smoking adults, 29 men and 31 women. All urine was collected at six time points during two 24 h periods. Blood samples were also collected twice and stored frozen. Analyses of creatinine in urine was performed in fresh urine using an enzymatic method. For creatinine in urine, the intra-class correlation (ICC) was calculated for 24 h urine and spot samples. Diurnal variability was examined, as well as association with urinary flow rate. The creatinine excretion rate was lowest in overnight samples and relatively constant in the other five samples. The creatinine excretion rate in each individual was positively correlated with urinary flow rate. The creatinine concentration was highest in the overnight sample and at 09:30. For 24 h samples the ICC was 0.64, for overnight samples it was 0.5, and for all spot samples, it was much lower. The ICC for urinary creatinine depends on the time of day of sampling. Frozen samples from this variability biobank are open for researchers examining normal variability of their favorite biomarker(s).

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