The effect of various modifiers on the course of periodontitis

2021 ◽  
pp. 48-54
Author(s):  
T.L. Redinova ◽  
E.V. Chikurova ◽  
D.K. Perevoshchikova ◽  
E.P. Stepanova ◽  
A.P. Petrova
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Alveolar Bone ◽  
Clinical Manifestations ◽  
Volume Data ◽  
Vascular Changes ◽  
Internal Organs ◽  
Rate Of Progression ◽  
Indirect Indicator

The purpose of the work is to establish the degree of influence of various modifiers on the course of chronic generalized periodontitis. We examined 83 periodontal patients. During the examination, in addition to the obligatory volume, data on somatic burden and dependence on smoking were included with the determination of the number of cigarettes smoked per day. Bleeding of the gums was determined in the area of all teeth. To determine the rate of progression of periodontitis on the basis of orthopantomogram data, an indirect indicator was calculated — the decrease in the alveolar bone in relation to the patient's age. It was established by the research that the modeling of periodontitis, with an identical hygienic state of the oral cavity of patients, is affected by concomitant somatic pathology, especially diabetes mellitus, making the course of periodontitis worse; and also a bad habit — smoking, which contributes to more pronounced vascular changes in the periodontium in patients with clinical manifestations of periodontitis. Recommendations are given to take into account the concomitant pathology of internal organs and the degree of dependence of patients on tobacco smoking when planning periodontal treatment, in order to correct these risk factors and motivate the patient to cooperate with a doctor.

Algorithm of diagnosis and treatment of patients with distal occlusion in the period of replacement bite

2021 ◽  
pp. 48-54
Author(s):  
T.L. Redinova ◽  
E.V. Chikurova ◽  
D.K. Perevoshchikova ◽  
E.P. Stepanova ◽  
A.P. Petrova
Keyword(s):  
Diabetes Mellitus ◽  
Alveolar Bone ◽  
Clinical Manifestations ◽  
Volume Data ◽  
Vascular Changes ◽  
Internal Organs ◽  
Rate Of Progression ◽  
Indirect Indicator ◽  
Distal Occlusion

The purpose of the work is to establish the degree of influence of various modifiers on the course of chronic generalized periodontitis. We examined 83 periodontal patients. During the examination, in addition to the obligatory volume, data on somatic burden and dependence on smoking were included with the determination of the number of cigarettes smoked per day. Bleeding of the gums was determined in the area of all teeth. To determine the rate of progression of periodontitis on the basis of orthopantomogram data, an indirect indicator was calculated — the decrease in the alveolar bone in relation to the patient's age. It was established by the research that the modeling of periodontitis, with an identical hygienic state of the oral cavity of patients, is affected by concomitant somatic pathology, especially diabetes mellitus, making the course of periodontitis worse; and also a bad habit — smoking, which contributes to more pronounced vascular changes in the periodontium in patients with clinical manifestations of periodontitis. Recommendations are given to take into account the concomitant pathology of internal organs and the degree of dependence of patients on tobacco smoking when planning periodontal treatment, in order to correct these risk factors and motivate the patient to cooperate with a doctor.

scholarly journals Clinical manifestations and risk factors of coronary artery disease in patients with diabetes mellitus in western Siberia

2010 ◽  
Vol 69 (3) ◽  
pp. 278-284
Author(s):  
Vadim A. Kuznetsov ◽  
Elena I. Yaroslavskaya ◽  
Marina I. Bessonova ◽  
Ivan S. Bessonov ◽  
Igor P. Zyrianov ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Western Siberia ◽  
Clinical Manifestations ◽  
Patients With Diabetes ◽  
Artery Disease

scholarly journals Leriche Syndrome as a Long-Term Continuum of Vascular Injury: from the Initial Clinical Manifestations to Possible Fatal Outcome (Significance of Interdisciplinary Cooperation Based on Own Clinical Observations)

2020 ◽  
pp. 108-124
Author(s):  
V Rudichenko ◽  
A Kushneryk ◽  
V Reizin
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Erectile Dysfunction ◽  
Strong Predictor ◽  
Psychiatric Morbidity ◽  
Fatal Outcome ◽  
Clinical Manifestations ◽  
Lower Limbs ◽  
Clinical Observations ◽  
Leriche Syndrome

Leriche syndrome typical signs include incapability for erection maintaining, fatigue feeling originating from both lower limbs, bilateral claudication with ischemic pain and lack or reduction of peripheral pulse (starting from femoral segment) combined with paleness or coldness of both lower limbs. The disease commonly affects men, and risk factors include hypertension, diabetes mellitus, hyperlipidemia and smoking. Currently the disorder is referred to type D aortoiliac injuries according to Trans-Atlantic Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). Data on psychiatric morbidity in Leriche syndrome is scarce. Some publications are dedicated in such a state to depressive disorder and erectile dysfunction, which were observed in psychiatric outpatient department. These may have several reasons, such as obesity, hypertension, diabetes mellitus, hypercholesterolemia and lower urinary tract symptoms. Moreover, erectile dysfunction is believed to be a strong predictor of general and coronary atherosclerosis. Leriche syndrome and penis arteries obstructive disease are considered to be two main reasons of impotence. Other reasons of Leriche syndrome may be lifestyle factors which are common with atherosclerosis: insufficient physical exercises, imbalanced diet and smoking. Statistics on psychiatric morbidity in Leriche syndrome is hard to receive because of multiple risk factors, partially because of atherosclerosis, which is the risk for vascular depression. The article represents historical data about prominent doctors in the history of vascular surgery who touched upon the problems of Leriche syndrome. The authors describe their own clinical observations of acute patient with prolonged development of full clinical manifestation with fatal outcome.

scholarly journals Root Causes of Fungal Coinfections in COVID-19 Infected Patients

2021 ◽  
Vol 13 (4) ◽  
pp. 1018-1035
Author(s):  
Arman Amin ◽  
Artin Vartanian ◽  
Nicole Poladian ◽  
Alexander Voloshko ◽  
Aram Yegiazaryan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Mechanical Ventilation ◽  
Patient Outcomes ◽  
Fungal Pathogens ◽  
Healthcare Providers ◽  
Clinical Manifestations ◽  
Middle Income ◽  
Middle Income Countries ◽  
Favorable Conditions

COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has infected over 200 million people, causing over 4 million deaths. COVID-19 infection has been shown to lead to hypoxia, immunosuppression, host iron depletion, hyperglycemia secondary to diabetes mellitus, as well as prolonged hospitalizations. These clinical manifestations provide favorable conditions for opportunistic fungal pathogens to infect hosts with COVID-19. Interventions such as treatment with corticosteroids and mechanical ventilation may further predispose COVID-19 patients to acquiring fungal coinfections. Our literature review found that fungal coinfections in COVID-19 infected patients were most commonly caused by Aspergillus, Candida species, Cryptococcus neoformans, and fungi of the Mucorales order. The distribution of these infections, particularly Mucormycosis, was found to be markedly skewed towards low- and middle-income countries. The purpose of this review is to identify possible explanations for the increase in fungal coinfections seen in COVID-19 infected patients so that physicians and healthcare providers can be conscious of factors that may predispose these patients to fungal coinfections in order to provide more favorable patient outcomes. After identifying risk factors for coinfections, measures should be taken to minimize the dosage and duration of drugs such as corticosteroids, immunosuppressants, and antibiotics.

scholarly journals Potential Markers of Arterial and/or Venous Thromboses and their Complications in Primary Antiphospholipid Syndrome

2007 ◽  
Vol 26 (4) ◽  
pp. 259-268
Author(s):  
Mirjana Bećarević ◽  
Nada Majkić-Singh
Keyword(s):  
Risk Factors ◽  
Antiphospholipid Syndrome ◽  
Clinical Manifestations ◽  
Primary Antiphospholipid Syndrome ◽  
Number Of Patients ◽  
Increased Risk ◽  
Significant Difference ◽  
Recurrent Abortions ◽  
Venous Thromboses

Potential Markers of Arterial and/or Venous Thromboses and their Complications in Primary Antiphospholipid SyndromeAntiphospholipid syndrome is characterized by venous or arterial thromboses and/or recurrent abortions accompanied by antiphospholipid antibodies and it can be primary (PAPS) or secondary (SAPS) to another disease. Arterial thromboses are less common than venous and most frequently they manifest as ischemia or infarction. Venous thromboses are usually multiple and bilateral and the most common complication of venous thromboses are pulmonary emboli. Considering that laboratory diagnosis of PAPS is currently based on persistently positive aCL, aβ2gpl and/or LA tests, and that neither one of those tests can discriminate between PAPS patients with arterial or venous thromboses or their complications, the aim of this study was to investigate the diagnostical significance of the determination of apo(a), oxLDL, anti-oxLDL antibodies, antianxA5 antibodies, hsCRP, C3 and C4 complement components and HPT for discrimination between PAPS patients with diverse clinical manifestations. Considering that elevated oxLDL and anti-oxLDL antibodies concentrations were found in PAPS patients, and also in subgroups of PAPS patients with MI or PE, it can be concluded that those parameters represent additional risk factors which together with other factors may lead to thromboses and their complications in PAPS. Regarding the fact that C3 and C4 concentrations were decreased in PAPS patients and that a positive correlation was found between hsCRP and C3 concentrations, this finding could indicate potential roles of these parameters as markers of atherosclerosis, which represents the leading cause of morbidity and mortality. HPT and apo(a) concentrations are not independent risk factors for MI in PAPS because lower levels were found in those patients in comparison to MI survivors without PAPS. No significant correlation of anti-anxA5 antibodies and the presence of arterial or venous thromboses or their complications was found, but increased concentrations of the IgG isotype of those antibodies could be a marker for recurrent abortions in PAPS, although this finding should be further investigated on a larger number of patients with this clinical finding. Determination of hsCRP in PAPS patients could not be an adequate parameter which would provide discrimination between patients with increased risk for development and/or recurrence of venous and/or arterial thromboses, nor for their complications, because no statistically significant difference in concentrations of this parameter was found among PAPS, IM, PE and SLE patients who were included in this study.

scholarly journals Analysis of Risk Factors Related to Coronary Heart Disease among Women Aged Older than 45 Years Old

2016 ◽  
Vol 11 (2) ◽  
Author(s):  
Masriadi Masriadi ◽  
Hasta Handayani Idrus ◽  
Arman Arman
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Air Force ◽  
Primary Data ◽  
Significant Relation ◽  
Purposive Sampling ◽  
B Test

Cardiovascular disease causes 8.6 million deaths of women every year, which is the major cause of death by one-third of all deaths of women in the world. Half of all deaths of women older than 50 years old is caused by cardiovascular and stroke diseases. This study aimed to analyze risk factors related to coronary heart disease among women aged older than 45 years at Dody Sarjoto Makassar Air Force Hospital 2016. The total of sample was 76 consisting of 64 cases of coronary heart disease and 12 non-coronary heart disease. Determination of sample used purposive sampling. Primary data were obtained through interview to respondents using questionnaire and direct interview. Data were analyzed by using contingency correlation coefficient (Exp (B)) test to identify significant relation between dependent and independent variables. Results found were hypertension (Exp (B) = 0.309), obesity (Exp (B) = 0.140), diabetes mellitus (Exp (B) = 0.164) and dyslipidemia (Exp (B) = 0.185), as proven having relation with coronary heart disease among women aged older than 45 years, and the factor which had the most significant relation was dyslipidemia.AbstrakPenyakit kardiovaskuler menyebabkan 8.6 juta kematian pada perempuan setiap tahun, yang merupakan penyebab kematian terbanyak, yaitu sepertiga dari seluruh kematian perempuan di seluruh dunia. Setengah dari seluruh kematian perempuan berusia di atas 50 tahun disebabkan oleh penyakit jantung dan stroke. Penelitian ini bertujuan untuk menganalisis faktor yang berhubungan dengan penyakit jantung koroner pada perempuan usia > 45 tahun di Rumah Sakit TNI AU Dody Sarjoto Makassar. Besar sampel sebanyak 76 sampel yang terdiri dari 64 kasus penyakit jantung koroner dan 12 kasus non penyakit jantung koroner. Penentuan sampel menggunakan metode purposive sampling. Data primer diperoleh melalui wawancara terhadap responden dengan menggunakan kuesioner dan wawancara langsung. Data dianalisis menggunakan uji koefisien korelasi kontingensi (Exp (B)) terhadap variabel independen dan dependen. Adapun hasil yang ditemukan adalah obesitas (Exp (B) = 0.140), diabetes mellitus (Exp (B) = 0.164), dan dislipidemia (Exp (B) = 0.185) terbukti memiliki hubungan dengan kejadian penyakit jantung koroner pada perempuan usia > 45 tahun dan faktor yang memiliki hubungan paling besar adalah dislipidemia.

Determination of clinical and metabolic features in pre- and postmenopausal women with type 2 diabetes mellitus and osteoarthrosis against the background of visfatin metabolism disorders

2021 ◽  
Author(s):  
V. O. Cherpita
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Postmenopausal Women ◽  
Clinical Manifestations ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Healthy Women

Objective — to determine the clinical and metabolic features of pre‑ and postmenopausal women with type 2 diabetes mellitus (DM2) and osteoarthritis (OA) against the background of impaired metabolism of visfatin (VF). Materials and methods. 120 pre‑ and postmenopausal women were selected for the study and divided into 3 groups: group 1 included women with isolated DM2; group 2 — women with isolated OA; group 3 — women with DM2, combined with OA. The control group consisted of 16 healthy women. Investigations included anthropometric measurements, assessment of the indices of lipid and carbohydrate exchange and clinical manifestations of premenopause and postmenopause. Determination of the serum VF levels of patients was performed by enzyme‑linked immunosorbent assay on the analyzer «Labline‑90» (Austria). Results. Investigation of the specific features of the DM2 and OA course in premenopausal women demonstrated violations of carbohydrate and lipid metabolism, defined by the significant (р < 0.001) increase in VF levels up to (3.9 ± 1.2 ng/ml) and (4.2 ± 1.1 ng/ml), respectively. The highest VF level was recorded in the group of comorbid DM2 and OA (5.5 ± 1.0 ng/ml) compared with the levels of relatively healthy women of the same age group (1.8 ± 0.5 ng/ml). Moreover, the high indices of body mass index, waist and hip circumference, systolic and diastolic pressure, as well as of the menopausal index were established at DM2 and OA vs control group. Conclusions. Clinical and metabolic disorders have been identified in pre‑ and postmenopausal women against the background of OA and DM2 based on the significant (р < 0.001) increase in visfatin levels, especially in case of comorbid OA and DM2, as compared to the control group of age‑matched practically healthy women.

scholarly journals Diagnosis of diabetic autonomous cardioneuropathy in patients with type 1 diabetes mellitus

2009 ◽  
Vol 12 (4) ◽  
pp. 55-60 ◽  
Author(s):  
Farida Vadutovna Valeeva ◽  
Maria Rustemovna Shaydullina
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 1 Diabetes ◽  
Early Diagnosis ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Manifestations ◽  
Diabetic Complication ◽  
Small Fiber

Autonomous cardiac neuropathy is a diabetic complication characterized by early disseminated sympathetic and parasympathetic small-fiber neuronaldegeneration. Prevalence, pathogenesis, risk factors, clinical manifestations, and early diagnosis of pathology are discussed.

scholarly journals COVID-19 and Type 2 Diabetes Mellitus

2021 ◽  
Author(s):  
Ritwika Mallik ◽  
Mohammed S.B. Huda
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Clinical Manifestations ◽  
Modifiable Risk Factors ◽  
Global Crisis ◽  
Community People

COVID-19 pandemic caused by SARS-COV-2 virus has evolved into a global crisis and is a major concern especially for the diabetes community. People with diabetes mellitus have increased morbidity and mortality associated with COVID-19 infection. Conversely, COVID-19 infection and treatment may predispose to hyperglycemia. Potentially modifiable risk factors have been discussed and urgent need to mitigate the risks is warranted. In this book chapter we summarize the available evidence on COVID-19 and type 2 diabetes mellitus including link between COVID-19 and type 2 diabetes, pathophysiology, clinical manifestations, management and complications.

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