scholarly journals PROFIL TUMOR JINAK KULIT DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R. D KANDOU MANADO PERIODE 2009-2011

e-CliniC ◽  
2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Grace Agustin Gefilem

Abstract: Introduction: Benign skin tumor manifestation of chaos skin growths that are congenital or akuisita, without the invasive and metastatic tendency, can be derived from vascular and non-vascular. Benign tumors was often said to be dangerouly because it is not develop into malignant tumors, howver skin tumor needs to be understood because causing disability (ruin the appearance) and also at an advanced stage can be fatal in body health.Objective: To know the profile of patients benign skin tumor, age, gender and employment in the Dermatology Clinic Dr Prof Dr. R. D. Kandou Manado for 3 years (January 2009 - December 2011). Subjects and Methods: A retrospective study of benign skin tumor of the medical records of new patients based on tumor type, age, sex, and occupation.Results: There were 478 (15.65%) patients of benign skin tumor among 3055 new patients. Verruca vulgaris (28.03%) and seborrheic keratosis (24.69%) most frequently encountered. Highest age group is 15-44 years is 49.16%. The ratio of men and women for benign skin tumor is 1:1,12. Most jobs are housewives (26.36%). Conclusion: verruca vulgaris is the most benign skin tumor. Benign skin tumor was more common in women. Highest age group is 15-44 years. Most jobs are housewives.Keywords: skin tumors, benignAbstrakPendahuluan: Tumor jinak kulit merupakan manifestasi dari kekacauan pertumbuhan kulit yang bersifat kongenital atau akuisita, tanpa tendensi invasif dan metastasis, dapat berasal dari vaskuler dan non vaskuler. Tumor jinak sering dikatakan tidak berbahaya karena tidak sampai berkembang menjadi keganasan namun demikian, tumor kulit perlu dipahami karena selain menyebabkan kecacatan (merusak penampilan) juga pada stadium lanjut dapat berakibat fatal kesehatan tubuh.Tujuan: Mengetahui profil pasien tumor jinak kulit berdasarkan jenis tumor, umur, jenis kelamin dan pekerjaan di Poliklinik Kulit dan Kelamin RSUP Prof Dr. R. D. Kandou Manado selama 3 tahun (Januari 2009- Desember 2011).Subyek dan Metode: Penelitian retrospektif tumor jinak kulit terhadap catatan medis kasus baru berdasarkan jenis tumor, usia, jenis kelamin, dan pekerjaan.Hasil: Terdapat 478 (15,65 %) pasien tumor jinak kulit di antara 3055 pasien baru. Veruka vulgaris (28,03%) dan keratosis seboroik (24,69%) paling sering dijumpai. Kelompok usia terbanyak adalah 15–44 tahun sejumlah 49,16%. Rasio laki-laki dan perempuan untuk tumor jinak kulit ialah 1:1,12. Pekerjaan terbanyak ialah ibu rumah tangga (26,36%).Kesimpulan: Veruka vulgaris merupakan tumor kulit jinak terbanyak. Tumor kulit jinak lebih sering terjadi pada perempuan. Kelompok usia tertinggi adalah 15–44 tahun. Pekerjaan terbanyak adalah ibu rumah tangga.Kata kunci: tumor kulit, jinak

2012 ◽  
Vol 22 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Kidong Kim ◽  
Soo Youn Cho ◽  
Sang-Il Park ◽  
Hye Jin Kang ◽  
Beob-Jong Kim ◽  
...  

ObjectiveThe objectives were to evaluate the risk of malignant adnexal tumors in women with nongynecologic malignancies and to identify variables associated with the risk of malignant adnexal tumors.MethodsThe eligibility criteria included the diagnosis of a nongynecologic malignancy and adnexal tumors, which were resected or subjected to biopsy at our institute between 1999 and 2010. The risk of malignant adnexal tumors was assessed by dividing the number of patients with metastatic tumors to the adnexa or primary adnexal cancers by the total number of patients. The association of clinicopathologic variables with the risk of malignant adnexal tumors was evaluated using the Fisher exact test and binary logistic regression analysis. In patients with metastatic tumors to the adnexa, the association of clinicopathologic variables with overall survival after adnexal surgery was examined using the log-rank test.ResultsIn 166 patients with adnexal tumors, 41 benign tumors, 113 metastatic tumors to the adnexa, and 12 primary adnexal cancers were diagnosed. Age older than 46 years, a tumor type associated with a high risk for malignant adnexal tumors, and bilateral tumors significantly increased the risk of malignant adnexal tumors. The overall survival of the patients with stomach cancer was significantly worse than the patients with colorectal or breast cancers.ConclusionOne hundred twenty-five of the 166 patients with nongynecologic malignancies who had adnexal tumors managed surgically were shown to have malignant tumors, and most of the tumors were metastatic from primary sites. The risk of malignant adnexal tumors was associated with age, nongynecologic malignancy, and bilaterality.


Author(s):  
Sahana N. Naik ◽  
Sunil Kumar K. S. ◽  
Girija B.

Background: Ovarian tumors account for 30% of all cancers of female genital tract which represents the sixth most common cancer and fourth leading cause of death in women. The present study was done with an objective to determine the frequency and distribution of various ovarian tumors and to study their clinical and histopathological presentations.Methods: It is a retrospective observational study of patients with ovarian tumors subjected to surgery in the department of obstetrics and gynecology, SDM College of Medical Sciences and Hospital from January 2005 to December 2015.Results: There were 642 cases comprising of 77.7% of neoplastic lesions and 22.3% of non-neoplastic lesions. Majority of the ovarian tumors (83%) were seen in the age group of 20 to 50 years. Mean age for ovarian tumors was 38 years.  Among the neoplastic lesions 84% were benign, 14.2% were malignant and 1.8% were borderline tumors. Surface epithelial tumors were the commonest tumors (60.9%) followed by germ cell tumors (12.8%).  Serous cystadenoma was the most common benign tumors (47.1%) followed by mucinous cystadenoma (18.4%). Among the ovarian malignant tumors; serous cystadenocarcinoma was the most common (4.5%) followed by mucinous cystadenocarcinoma (2.6%). Chocolate cysts were the most common among the non-neoplastic lesions (36.4%).Conclusions: Ovarian neoplastic lesions were more common than non-neoplastic lesions. Benign ovarian tumors were common in reproductive age group.  The mean age of occurrence for ovarian tumor was 38 years. The most common neoplasm was surface epithelial tumors, of which serous tumors was the commonest. Chocolate cysts were the most frequently encountered histopathological finding among the non-neoplastic lesions.


e-CliniC ◽  
2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Aljufri Syamsudin ◽  
Marlyn G. Kapantow ◽  
Renate T. Kandou

Abstract: Candidiasis vulvovaginalis (candida vulvovaginitis) is an infection of the vagina or vulva by Candida genus, with a variety of clinical manifestations that can occur acutely, chronically, or episodically. This study aimed to determine the profile of candidiasis vuvovaginalis in the Dermatology clinic Prof. Dr. R. D. Kandou Manado during the period of January to December 2012. This was a retrospective study using the medical records of new patients with a diagnosis of candidiasis vulvovaginalis. The results showed that there were 30 patients (2.73%) with candidiasis vulvovaginalis among 1096 new patients. It was more commonly found in women with the largest age group 25-44 years, residence in Manado, and as housewives, The most frequent therapy was systemic antifungals and antihistamine. The occurence of this disease was associated with other diseases such as bacterial vaginosis.Keywords: vulvovaginaliscandidosis, candida albicansAbstrak: Kandidiasis vulvovaginalis (kandidosis vulvovaginalis, kandida vulvovaginitis) adalah infeksi vagina dan atau vulva oleh Genus Candida, dengan berbagai manifestasi klinisnya yang bisa berlangsung akut, kronis atau episodik. Penelitian ini bertujuan untuk mengetahui profil kandidiasis vuvovaginalis di poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari – Desember 2012. Penelitian ini dilakukan secara retrospektif dari rekam medik pasien baru dengan diagnosis kandidiasis vulvovaginalis. Hasil penelitian menunjukkan bahwa terdapat 30 pasien (2,73%) kandidiasis vulvovaginalis dari 1.096 pasien baru, lebih banyak ditemukan pada perempuan dengan kelompok umur 25-44 tahun, didapatkan bahwa wilayah tempat tinggal terbanyak adalah Kota Manado, menurut pekerjaan paling banyak terjadi pada IRT (Ibu rumah tangga), terapi yang banyak digunakan adalah Antijamur sistemik+antihistamin, dan kombinasi kandidiasis vulvovaginalis dengan penyakit lain terbanyak yaitu kandidiasis vulvovaginalis + bakterial vaginosis.Kata kunci: kandidiasis vulvovaginalis, candida albican, penelitian retrospektif


2004 ◽  
Vol 14 (1) ◽  
pp. 89-93 ◽  
Author(s):  
A. M. Makhlouf ◽  
M. M. Fathalla ◽  
M. A. Zakhary ◽  
M. H. Makarem

ObjectivesTo investigate the expression of sulfatides in the tissue homogenates of malignant ovarian tumors, benign ovarian tumors, and control tissues and to study the relation between this marker and other clinico-pathological criteria such as the tumor type, grade of differentiation, surgical stage and ovulatory years.DesignCross-sectional study.SettingDepartment of Obstetrics and Gynecology and Department of Biochemistry, Assuit university hospital.SubjectsForty-six patients had malignant ovarian tumors. Sixteen patients had benign ovarian neoplasm. Thirty patients, with normal ovaries, represented the control group.MethodsA sample of the tumor or from the normal ovary (the control group) was sent for histopathological and biochemical examination. Sulfatides were measured by a rapid and sensitive spectrophotometric method.ResultsThere was a significant rise in benign tumors [median and range 43 (38–53)], than in the control group, 21 (18–31), P-value = 0.000. In malignant tumors, the median value of sulfatides was significantly higher than in benign tumors [127 (71–193), P-value = 0.000]. Sulfatides were significantly higher in patients with more ovulatory years and tumors of advanced stages (stage III/IV) and poor differentiation.ConclusionsSulfatides may play a role in the pathogenesis of benign and malignant ovarian tumors. It may also predict advanced stages in patients who are apparently early stage. It is also a candidate to study of their association with response to chemotherapy.


1970 ◽  
Vol 1 (1) ◽  
pp. 9-12 ◽  
Author(s):  
P Lavaju ◽  
SK Arya ◽  
A Sinha ◽  
S Pandey ◽  
S Adhikari ◽  
...  

Background: Ocular tumors are commonly encountered in ophthalmic practice. Objective: To study the clinical pattern of ocular tumors in the eastern region of Nepal. Materials and methods: The hospital records of patients with ocular tumors treated at B P Koirala Institute of Health Sciences in the eastern region of Nepal over a period of 5 years (April 2003 - March 2008) were studied retrospectively. Results: Of 115 consecutive patients with ocular tumors, 40 (34.75%) were below the age of 21 years, 41 (35.65%) were in the age group of 21-50 years and 34 (29.56%) of age above 50 years. There were 48 (41.73%) and 67 (58.26%) patients with benign and malignant tumors respectively. The common benign tumors were conjunctival papilloma, dermoid cysts, nevus, cystic lesions and hemangioma. Among the malignant tumors, basal cell carcinoma was the commonest (22.38%). Retinoblastoma was the most common ocular malignant tumor in the pediatric age group (88.8%). Basal cell carcinoma was the commonest eyelid malignancy 53.57%. Conclusion: Conjunctival papilloma, dermoid cysts, nevus, cystic lesions and hemangioma are common benign ocular tumors, whereas basal cell carcinoma and retinoblastoma are the commonest ocular malignancies in adults and children respectively. Key words: ocular malignancy; retinoblastoma; basal cell carcinoma DOI: 10.3126/nepjoph.v1i1.3667 Nep J Oph 2009;1(1):9-12


2008 ◽  
Vol 44 (6) ◽  
pp. 308-319 ◽  
Author(s):  
Jason A. Syrcle ◽  
Jennifer J. Bonczynski ◽  
Sebastien Monette ◽  
Philip J. Bergman

In this retrospective study of 42 cases of lingual tumors in dogs, 27 (64%) were malignant, and 15 (36%) were benign. Median survival time for dogs with benign tumors was >1607 days, compared to 286 days for malignant tumors. Prognostic factors significantly associated with increased survival included complete histological margins (P=0.036), smaller tumor size (P=0.003), and benign tumor type (P=0.011). Smaller tumors were more likely to be completely resected (P=0.008) and were less likely to recur (P=0.001). Partial or subtotal glossectomies were performed in 13 cases. Short-term morbidity associated with glossectomy included ptyalism and dehiscence. Long-term morbidity included minor changes in eating and drinking habits.


2021 ◽  
pp. 43-44
Author(s):  
Momota Naiding ◽  
Nitu Mani Khakhlari ◽  
Nandakanta Mahanta ◽  
Shah Alam Sheikh

Introduction : Ovarian tumor accounts for 30% of female genital tract cancers and comprises of large variety of neoplastic entities. Mortality rate has due to ovarian tumor has gradually increased. The present study was undertaken to study the frequency of various histomorphological spectrum, histological subtypes and age distribution pattern of ovarian tumors. Methods: Retrospective study was carried during period of 1st January 2015 to 31st st December 2019, 455 cases of ovarian neoplastic lesions were taken from the records of the department. Classication was done according to WHO classication. Results: Of the 455 cases, 332 cases (73%) were benign, 16 cases (3.5%) cases were borderline and 107 cases (23.5%) cases were malignant. Among the histological subtypes surface epithelial tumors are common comprised of 76.9% followed by germ cell tumors (19.6%). Serous cystadenoma (42.8%) was the most common benign tumor followed by mature cystic teratoma (16.5%). Among the malignant tumors, the most common was Serous cyst adenocarcinoma (11.9%) Tumors were seen over age range of 11-81 years. Maximum number of cases were in the 4th to 6th decade. Benign tumors were primarily seen in Younger age group , whereas malignant tumors were common in elderly age group. Conclusions: In our study we analysed all the spectrum of ovarian tumors diagnosed on the basis of histomorphology. Surface epithelial tumors were the commonest ovarian tumor. Maximum numbers of ovarian tumors were in the age range 40-59years and malignant tumors were common in age >40 years


Author(s):  
Priya V.

Background: Adolescence is the period of transition from childhood to adulthood. 1% neoplasm occurs in this age group below 17 years, of this, 3% are ovarian neoplasms. Aim was to study retrospectively the clinicopathological profile and outcome of ovarian tumors in the age group 10-20 years in Government Medical College, Kottayam, Kerala, India from January 2008 for six years.Methods: Fifty Patients who have undergone laparotomy in this institution during the period were taken for study. Data regarding age, mode of presentation, diagnostic methods, treatment and histopathology were recorded. Follow-up was also taken into consideration. Patients with polycystic ovary, corpus luteal cyst, follicular cyst and endometriotic cyst are excluded.Results: Majority of the patients fall between the age group 15-20 years. Major clinical presentation was pain (40%), followed by abdominal mass. Laparotomy was done for all cases except three where laparoscopy was done. Imprint cytology taken for 3 cases. Histopathology showed malignant tumors in 6 cases and benign tumors in 44 cases. Epithelial tumors outnumbered germ cell tumors.Conclusions: This study shows the predominance of epithelial neoplasms in the age group 10-20 years. Proportion of malignancy is 12%.


1998 ◽  
Vol 35 (3) ◽  
pp. 168-177 ◽  
Author(s):  
K. A. Schafer ◽  
G. Kelly ◽  
R. Schrader ◽  
W. C. Griffith ◽  
B. A. Muggenburg ◽  
...  

Intact female Beagles from life-span studies in the Lovelace Respiratory Research Institute colony were examined for mammary tumor incidence. The breeding colony, founded in 1963, produced five generations from 28 founder females. After proportional hazards analysis, two maternal families were shown to have markedly different phenotypes, one susceptible and one resistant to mammary neoplasia, as compared with the entire colony. When tumors were subdivided into benign and malignant based on local invasiveness, familial differences in tumor incidence were preserved for each tumor type. Fifty-seven females in the susceptible family developed 149 benign and 39 malignant tumors, and 95 females in the resistant family developed 70 benign and 20 malignant tumors. The ratio of benign to malignant tumors of about 4:1 for both families was higher than expected. Using Kaplan–Meier and log-rank analyses, the susceptible family had a 50% malignant tumor incidence by age 13.6 years, whereas the resistant family did not have a 50% incidence until 17.0 years ( P = 0.0065). Because of marked censoring, Kaplan–Meier analyses could not provide an estimate of the 50% benign tumor incidence; mean incidence age was calculated instead. These estimates for benign tumors for susceptible and resistant families were 10.8 and 13.8 years ( P = 0.0001), respectively. Using χ2 tests, families had no differences in the occurrence of the types of benign ( P = 0.098) or malignant ( P = 0.194) tumors or in the ratio of benign to malignant tumors ( P = 0.778). Immunohistochemical analysis of malignant tumors from both families did not demonstrate differences in p53 mutation rate or p185 erbB-2 expression. These results suggest that 1) genetic factors produce familial differences in the age of onset of both benign and malignant mammary tumors; histologic types do not segregate by family; 2) the ratio of benign to malignant tumors is greater than formerly reported; and 3) neither p53 nor p185 erbB-2 alterations are the basis for the familial predisposition.


2021 ◽  
Author(s):  
wei yang ◽  
Yingjie Cai ◽  
Jiashu Chen ◽  
Ping Yang ◽  
Zesheng Ying ◽  
...  

Abstract Objective Brain tumors have become the most common solid tumors in children. The epidemiology is poorly described in China. This retrospective study aimed to describe the epidemiologic characteristics, clinical presentation, and prognosis in national health center for children. Method From January 2015 to December 2020, 484 cases age 0-18 years old diagnosed with brain tumors and receiving neurosurgery treatment were enrolled into the database. Pathology was based on the World Health Organization 2012 nervous system tumor classification, and tumor behavior were classified on International Classification of Diseases for Oncology, third edition. A descriptive and comparative statistic was performed on clinical manifestation, symptom duration, sex, age, tumor location, tumor behavior, and survival time. Results Among the 484 brain tumors, the median age at diagnosis was 4.62 [2.19, 8.17] years old (4.07 [1.64, 7.13] for benign tumors and 5.36 [2.78, 8.84] for malignant tumors). The overall male to female ratios were 1.33:1, with 1.09:1 and 1.62:1 for benign and malignant tumors respectively. Nausea and vomiting, headache were the most frequent initial symptoms. The median symptoms duration was 4[2, 21] weeks. The three most frequent tumor type were embryonal tumors (22.45%), other astrocytic tumors (20.17%), and diffuse astrocytic tumors (11.02%). Supratentorial tumors comprise 57.38% of all brain tumors. And the most common tumor locations were cerebellum and forth ventricles (38.67%), sellar region (22.87%) and ventricles (10.60%). Male were more common among choroid plexus tumors (63.64%), embryonal tumors (61.11%), ependymal tumors (68.57%), and germ cell tumors (78.13%). Patients were followed for 1 to 82 months. The overall 5-year survival was 77.4%, with 90.0% for benign tumor and 65.3% for malignant tumors. log-rank test found significant different at p <0.001 level. Conclusion Brain tumors presented particularly sexual, age dependent, and regional dependent epidemiological characteristic. Our results were consistent with previous reports, and might reflect the real epidemiology status in China.


Sign in / Sign up

Export Citation Format

Share Document