scholarly journals KARSINOMA KANDUNG KEMIH

2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Samuel S. Senduk ◽  
Linda W.A Rotty

Abstract: We reported a case of bladder carcinoma in a male of 65 years. The main complaints were hematuria, urinary frequency, dysuria, urgency, loss of weight, and pain in the genital area spreading to the lower abdomen. Diagnosis made by clinical, laboratory, and cytological examinations had no result.  Final diagnosis was made by ultrasonography and cystoscopy, associated with transurethral biopsy and histopathological examination. The result was papillary transitional cell carcinoma, class II; and according to TNM it was a superficial bladder carcinoma in stadium at least T1. Transurethral resection of the tumor was done, and intravesical medicine was given (mitomycin C 40 mg once a week for 6 weeks). The patient was advised to stop smoking and drinking coffee. The prognosis was good. Key words: hematuria, bladder tumor, USG, cystoscopy, tansurethral resection.  Abstrak: Telah dilaporkan kasus karsinoma kandung kemih pada seorang laki-laki berusia 66 tahun. Keluhan utama: hematuri, urgensi, disuri, frekuensi, penurunan berat badan, dan nyeri di kemaluan sampai perut bagian bawah. Diagnosis yang ditegakkan berdasarkan pemeriksaan klinis, laboratorium, sitologi tidak memberi hasil positif. Diagnosis pasti ditegakkan berdasar-kan ultrasonografi dan sistoskopi, disertai biopsi transuretral dan pemeriksaan histopatologi.  Hasil yang diperoleh karsinoma sel transisional papiler kelas II, dan berdasarkan TNM sebagai karsinoma kandung kemih  superfisial dengan stadium sekurang-kurangnya T1. Penanganan yang dilakukan adalah reseksi tumor transuretral yang diikuti pemberian obat intravesika (mitomicyn C 40 mg sekali seminggu selama 6 minggu), dan penderita dianjurkan untuk berhenti merokok dan berhenti minum kopi. Prognosis penderita ini baik. Kata kunci: hematuria, tumor kandung kemih, USG, sistoskopi, reseksi transuretral.

2021 ◽  
Vol 14 (3) ◽  
pp. e239422
Author(s):  
Midori Tokushima ◽  
Masaki Tago ◽  
Naoko E Katsuki ◽  
Shu-ichi Yamashita

A 75-year-old woman developed redness and swelling on her truncal skin, spreading from the lower abdomen to left thigh, 2 months before being admitted to our hospital. She was urgently hospitalised because of her worsening respiratory condition. On admission, she had reticular telangiectasia, diffuse skin induration on the lower abdomen and panhypopituitarism. She was diagnosed with intravascular large B-cell lymphoma (IVLBCL) by the third random abdominal skin biopsy. After histopathological examination at autopsy, we made a final diagnosis of IVLBCL causing respiratory failure and panhypopituitarism. This is the rare case of IVLBCL-induced panhypopituitarism showing visible skin lesions.


JMS SKIMS ◽  
2017 ◽  
Vol 20 (1) ◽  
pp. 41-43
Author(s):  
Abdul Rasheed Rather ◽  
Shazia Bashir ◽  
Ather Hafiz Khan ◽  
Ashfaq Ul Hassan ◽  
Mohsin Ul Rasool ◽  
...  

Struma ovarii is a rare tumor of ovary which accounts for 1% of all ovarian tumors and 3% 0f all dermoid tumors. It belongs to the group of monodermal teratomas. We present a case of struma ovarii in a 55 year old women who presented with symptoms of pain in lower abdomen and loss of appetite for the last one month. Radiological investigations including USG, CT scan and MRI revealed a complex right adnexal lesion. Final diagnosis of struma ovarii was made on histopathological examination which revealed colloid filled thyroid follicles lined by cuboidal epithelium. JMS 2017; 20(1):41-43


2020 ◽  
pp. 1-3
Author(s):  
Radhika Mucharla ◽  
Ravikanth Kotagiri

Salivary gland tumours account for 2-6.5% of all the neoplasms of the Head and Neck. Histopathology is most important in diagnosis of salivary gland tumors. AIMS and OBJECTIVES : To study age,sex and site distribution of various salivary gland lesions, to study the histomorphologic (gross &microscopic) aspect of these lesions to correlate clinical diagnosis with that of histopathologic features. MATERIALS AND METHODS: The study is conducted in the RAINBOW CLINICAL LABORATORY AND RESEARCH CENTRE, SIDDIPET during the period of September2018 to September 2020. Formalin fixed ,paraffin embedded sections and stained with hematoxylin and eosin slides were studied. RESULTS: Total number of specimens were 54. Out of these 39 were neoplastic (benign 70%,malignant 30%) and 15 were non neoplastic. Among the benign tumors majority are pleomorphic adenoma.Among the malignant tumors, mucoepidermoid carcinoma is the most common. Among the non neoplastic lesions chronic sialadenitis is most common. CONCLUSION: Histopathological examination of salivary gland lesions stands out to be the most important method in establishing the final diagnosis. It helps in differentiating non neoplastic and neoplastic lesions.


2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e16087-e16087
Author(s):  
F. Smaili ◽  
A. Bounedjar ◽  
R. Ferhat ◽  
K. Bouzid

e16087 Background: Systemic intravenous gemcitabine is usually used in advanced bladder carcinoma, intravesical G is a novel treatment approach for TCC. In this study we evaluate the efficacy of intravesical Gemcitabine in patients (pts) with superficial bladder carcinoma. Methods: From February 2003 to June 2004, 60 pts (57M/3F) were enrolled in the study (M/F = 57/3). The median age was 59,5 years old (24–84). Nine pts had a carcinoma in situ (Cis) and 51 had pT1 lesions. Three weeks after a total transurethral resection (TUR), patients receive intravesical instillation of 2000 mg G every week for 6 weeks, than every month for six months. They received a total of 720 instillations, Follow up was with cystoscopy and urine cytology every six months. Results: At a median follow-up time 60 months, all patients were evaluable for tumor response: 23(38, 3%) patient had a persistant complete remission after treatment, 26 patients (43,3%) had a superficial relapse of TCC, six patients (10%) had progressive disease: four with muscle invasion and two with distant metastasis. Conclusions: Intravesical therapy with gemcitabine is active and well tolerated treatment in patients with superficial TCC carcinoma of the bladder. A phase III trial comparing GEM with intravesical BCG or MMC is warranted No significant financial relationships to disclose.


Author(s):  
Bhawana Pant ◽  
Sanjay Gaur ◽  
Prabhat Pant

F.NA.C has been used for ages as a safe and economical tool for fast preoperative diagnosis of parotid tumors. It has certain pitfall which sometimes leads to misdiagnosis and consequently it may have affect on treatment of the tumors. Keeping in view of the diverse classification of parotid tumors’ information from cytology should be combined with radiology as well as clinical diagnosis. Aim: To discuss some cases where there was discrepancy between cytological diagnosis and histopathological result and also suggest measures to improve the efficacy of F.N.A.C. Material and methods: The study includes 50 cases of parotid tumours who presented to the  department of ENT at Government medical college Haldwani which is a tertiary referral centre during 2009 to 2016. Only adult patients were included and inflammatory swelling were excluded from the study. All patients evaluated  Contrast enhanced computerized tomography(CECT) and  Magnetic resonance imaging (MRI) followed by Fine needle aspiration cytology .Preoperative diagnosis was made upon the findings of the above investigations and different types of  parotid surgeries  were done. . Final diagnosis was made on  histopathological  examination. Result :The most common tumour  came out to be pleomorphic adenoma (23 cases-46%) followed by mucoepidermoid carcinoma(12cases-24%). In ten  cases there was no clear cut  association between cytological diagnosis and final histopathological diagnosis. Conclusion: FNAC is highly sensitive and specific technique for diagnosis of many salivary gland swellings. FNAC can be used preoperatively to avoid unnecessary surgery and biopsy. Details of clinical information and radiologic features may help the pathologist to arrive at the appropriate diagnosis and reduce false interpretation. Pitfalls may also occur with improper technique of FNAC which can be overcome by proper caution.


1994 ◽  
Vol 30 (2) ◽  
pp. 347
Author(s):  
Mi Hye Kim ◽  
Kyung Sub Shinn ◽  
Hyun Kim ◽  
Ha Hun Song ◽  
Si Won Kang ◽  
...  

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 962-967
Author(s):  
Nami Sawada ◽  
Tamaki Morohashi ◽  
Tomokazu Mutoh ◽  
Tsukasa Kuwana ◽  
Junko Yamaguchi ◽  
...  

AbstractMoraxella lacunata (M. lacunata) is a Gram-negative bacterium, which rarely causes serious infection. This is a rare case report of acute glomerulonephritis diagnosed by pathological findings in a child accompanied by M. lacunata infection. The patient showed hematuria, proteinuria and hyperkalemia requiring emergency hemodialysis. After hospitalization, M. lacunata bacteremia became apparent. Pathological findings showed an increase in glomerulus inflammatory cells and glomerular C3 deposition was observed in the renal tissue biopsy. Final diagnosis was endocapillary proliferative glomerulonephritis. Clinical reports of M. lacunata infection requiring emergency hemodialysis in children are rare. Previous reports have suggested that lowered immune competency with chronic kidney disease may be a risk factor associated with serious invasive cases of M. lacunata infection. However, detailed clinical laboratory data and pathological findings have not been identified in previous case reports. Our case directly indicated complement activity and acute glomerulonephritis with M. lacunata infection. Although there are various causes for acute glomerulonephritis, infection-related glomerulonephritis (IRGN) is an important concept. M. lacunata infection might have a potential risk for IRGN with dysregulation of complement activity leading to serious and invasive clinical conditions than previously considered.


Cancer ◽  
2002 ◽  
Vol 94 (6) ◽  
pp. 1677-1684 ◽  
Author(s):  
Andrés Rodríguez-Alonso ◽  
Salvador Pita-Fernández ◽  
Joaquín González-Carreró ◽  
José Luis Nogueira-March

Author(s):  
Dharmpal Godara ◽  
Vijay Pal Singh Dhayal

Background: The present study highlights the occurrence of Incidental gallbladder carcinoma (IGBC) detected during histopathological examination in cholecystectomy specimens removed for cholelithiasis. Methods- This is a tertiary hospital based cross-sectional study of 500 cholecystectomy specimens removed during cholelithiasis. Relevant hospital records, histopathology slides and reports were reviewed, re-evaluated and studied. Results: 4(0.80%) cases of incidental gall bladder carcinoma (IGBC) were diagnosed from the histopathological evaluation (HPE) of 500 cholecystectomy specimens, constituting 0.80% of gall bladder specimens received during the study period. The age of the patients with IGBC ranged from 51-80 years. More females were affected than males with a M:F ratio of 1:3. Conclusion: Early detection of IGBC by histopathological examination would have a favourable impact on prognosis and management thereby increasing the survival outcome. Keywords: Cholelithiasis, Incidental Gall Bladder Carcinoma


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