scholarly journals Classification among Microaneurysms, Exudates, and Lesion free Retinal Regions in the Eye Images using Transfer Learned CNNs

2019 ◽  
Vol 9 (2) ◽  
pp. 5508-5512
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Diabetic Retinopathy ◽  
Glucose Level ◽  
Vision Loss ◽  
Early Stage ◽  
Training Data ◽  
Fundus Images ◽  
Diabetic Mellitus ◽  
Start Process

When pancreas fails to secrete sufficient insulin in the human body, the glucose level in blood either becomes too high or too low. This fluctuation in glucose level affects different body organs such as kidney, brain, and eye. When the complications start appearing in the eyes due to Diabetic Mellitus (DM), it is called Diabetic Retinopathy (DR). DR can be categorized in several classes based on the severity, it can be Microaneurysms (ME), Haemorrhages (HE), Hard and Soft Exudates (EX and SE). DR is a slow start process that starts with very mild symptoms, becomes moderate with the time and results in complete vision loss, if not detected on time. Early-stage detection may greatly bolster in vision loss. However, it is impassable to detect the symptoms of DR with naked eyes. Ophthalmologist harbor to the several approaches and algorithm which makes use of different Machine Learning (ML) methods and classifiers to overcome this disease. The burgeoning insistence of Convolutional Neural Network (CNN) and their advancement in extracting features from different fundus images captivate several researchers to strive on it. Transfer Learning (TL) techniques help to use pre-trained CNN on a dataset that has finite training data, especially that in under developing countries. In this work, we propose several CNN architecture along with distinct classifiers which segregate the different lesions (ME and EX) in DR images with very eye-catching accuracies.

scholarly journals Deep Neural Network for Predicting Diabetic Retinopathy from Risk Factors

Mathematics ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 1620 ◽  
Author(s):  
Ganjar Alfian ◽  
Muhammad Syafrudin ◽  
Norma Latif Fitriyani ◽  
Muhammad Anshari ◽  
Pavel Stasa ◽  
...  
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Risk Factors ◽  
Diabetic Retinopathy ◽  
Prediction Model ◽  
Deep Neural Network ◽  
Early Stage ◽  
Individual Risk ◽  
Proposed Model ◽  
Individual Risk Factors

Extracting information from individual risk factors provides an effective way to identify diabetes risk and associated complications, such as retinopathy, at an early stage. Deep learning and machine learning algorithms are being utilized to extract information from individual risk factors to improve early-stage diagnosis. This study proposes a deep neural network (DNN) combined with recursive feature elimination (RFE) to provide early prediction of diabetic retinopathy (DR) based on individual risk factors. The proposed model uses RFE to remove irrelevant features and DNN to classify the diseases. A publicly available dataset was utilized to predict DR during initial stages, for the proposed and several current best-practice models. The proposed model achieved 82.033% prediction accuracy, which was a significantly better performance than the current models. Thus, important risk factors for retinopathy can be successfully extracted using RFE. In addition, to evaluate the proposed prediction model robustness and generalization, we compared it with other machine learning models and datasets (nephropathy and hypertension–diabetes). The proposed prediction model will help improve early-stage retinopathy diagnosis based on individual risk factors.

scholarly journals DIABETIC RETINOPATHY IMAGE CLASSIFICATION USING DEEP NEURAL NETWORK

2017 ◽  
Vol 10 (13) ◽  
pp. 461
Author(s):  
Parvathy En ◽  
Bharadwaja Kumar G
Keyword(s):  
Neural Network ◽  
Diabetic Retinopathy ◽  
Image Classification ◽  
Vision Loss ◽  
Training Model ◽  
Fundus Images ◽  
Global Epidemic ◽  
Important Field ◽  
Severity Levels ◽  
Field Efficiency

Healthcare is an important field where image classification has an excellent value. An alarming healthcare problem recognized by the WHO that theworld suffers is diabetic retinopathy (DR). DR is a global epidemic which leads to the vision loss. Diagnosing the disease using fundus images is a timeconsuming task and needs experience clinicians to detect the small changes. Here, we are proposing an approach to diagnose the DR and its severity levels from fundus images using convolutional neural network algorithm (CNN). Using CNN, we are developing a training model which identifies the features through iterations. Later, this training model will classify the retina images of patients according to the severity levels. In healthcare field, efficiency and accuracy is important, so using deep learning algorithms for image classification can address these problems efficiently.

scholarly journals Numerical Simulation and Design of Computer Aided Diabetic Retinopathy Using Improved Convolutional Neural Network

2021 ◽  
Vol 9 (4) ◽  
pp. 23-27
Author(s):  
Lokesh Gupta ◽  
Dr. Saroj Hiranwal
Keyword(s):  
Neural Network ◽  
Diabetic Retinopathy ◽  
Image Classification ◽  
Vision Loss ◽  
Health Sector ◽  
Developed Countries ◽  
Superior Performance ◽  
Fundus Images ◽  
Healthcare Applications ◽  
Practical Applications

The health sector is entirely different from other sectors. It is a high priority department with the highest quality of care and quality, regardless of cost. It does not meet social standards even though it absorbs a lot of budget. Health specialists interpret much of the medical evidence. Due to its subjectivity, complexity of images, broad differences among various interpreters and exhaustion, the image interpretation of human experts is very restricted. It also offers an exciting solution with good medical imaging accuracy following in-depth learning in other practical applications and is considered an important tool in future healthcare applications. This chapter addresses the most advanced and optimised deep learning architecture for segmentation and classification of medical pictures. We addressed the complexities of healthcare imaging and open science based on profound learning in the previous segment. Diabetic retinopathy automated diagnosis is crucial because it is the primary cause of permanent vision loss in working-age people in developed countries. The early identification of diabetic retinopathy is extremely helpful in clinical treatment; although many different methods of extracting functions were suggested, the classification task of retinal images is still quite tedious for even those professional clinicians. Recently, in contrast with previous feature-based image-classification approaches, deep-convolutioned neural networks have demonstrated superior performance in image classification. Therefore in this research, we explored the use of deep-seated neural network techniques to identify diabetic retinopathy automatically with Color Fundus images in our datasets that are superior to classical ones. Deep convolutionary neural systems have since late been seen better output in the analysed image arrangement than previous components which have combined image order techniques that are focused on the crafting method. In this investigation, we studied the use of profound convolutionary strategy of the neural system to naturally classify diabetic retinopathy, using shading fundus images to achieve high precision in our datasets.

scholarly journals Pengaruh Preprocessing Terhadap Klasifikasi Diabetic Retinopathy dengan Pendekatan Transfer Learning Convolutional Neural Network

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Juan Elisha Widyaya ◽  
Setia Budi
Keyword(s):  
Neural Network ◽  
Diabetic Retinopathy ◽  
Convolutional Neural Network ◽  
Early Stage ◽  
Careful Examination ◽  
Fundus Images ◽  
Fundus Image ◽  
Retinal Fundus Image ◽  
Retinal Fundus Images ◽  
Retinal Fundus

Diabetic retinopathy (DR) is eye diseases caused by diabetic mellitus or sugar diseases. If DR is detected in early stage, the blindness that follow can be prevented. Ophthalmologist or eye clinician usually decide the stage of DR from retinal fundus images. Careful examination of retinal fundus images is time consuming task and require experienced clinicians or ophthalmologist but a computer which has been trained to recognize the DR stages can diagnose and give result in real-time manner. One approach of algorithm to train a computer to recognize an image is deep learning Convolutional Neural Network (CNN). CNN allows a computer to learn the features of an image, in our case is retinal fundus image, automatically. Preprocessing is usually done before a CNN model is trained. In this study, four preprocessing were carried out. Of the four preprocessing tested, preprocessing with CLAHE and unsharp masking on the green channel of the retinal fundus image give the best results with an accuracy of 79.79%, 82.97% precision, 74.64% recall, and 95.81% AUC. The CNN architecture used is Inception v3.

A Fully Convolutional Neural Network for Recognition of Diabetic Retinopathy in Fundus Images

2019 ◽  
Vol 12 ◽  
Author(s):  
Manaswini Jena ◽  
Smita Prava Mishra ◽  
Debahuti Mishra
Keyword(s):  
Neural Network ◽  
Diabetic Retinopathy ◽  
Convolutional Neural Network ◽  
Network Model ◽  
Visual Information ◽  
Vision Loss ◽  
Spatial Arrangement ◽  
Fundus Images ◽  
Neural Network Models ◽  
Proposed Model

Background: Diabetic retinopathy is one of the complexities of diabetics and a major cause of vision loss worldwide which come into sight due to prolonged diabetes. For the automatic detection of diabetic retinopathy through fundus images several technical approaches have been proposed. The visual information processing by convolutional neural network makes itself more suitable due to its spatial arrangement of units. Convolutional Neural Networks are at their peak of development and best results can be gained by proper use of the technique. The local connectivity, parameter sharing and pooling of hidden units are advantageous for various predictions. Objective: Objective of this paper is to design a model for classification of diabetic retinopathy. Method: A fully convolutional neural network model is developed to classify the diseased and healthy fundus images. Here, proposed neural network consists of six convolutional layers along with rectified linear unit activations and max pooling layers. The absence of fully connected layer reduces the computational complexity of the model and trains faster as compared to traditional convolutional neural network models. Result and Conclusion: The validation of the proposed model is accomplished by training it with a publicly available High-Resolution Fundus image database. The model is also compared with various existing state-of-the-art methods which show competitive result as compared to these models. A behavioural study of different parameters of the network model is represented. The intelligence of our model lies in its ability to re-tune weight to overcome outliers encountered in future. The proposed model works well with satisfactory performance.

scholarly journals Modelling on-demand preprocessing framework towards practical approach in clinical analysis of diabetic retinopathy

2022 ◽  
Vol 12 (1) ◽  
pp. 585
Author(s):  
Prakruthi Mandya Krishnegowda ◽  
Komarasamy Ganesan
Keyword(s):  
Diabetic Retinopathy ◽  
Vision Loss ◽  
Early Stage ◽  
Signal To Noise Ratio ◽  
Clinical Analysis ◽  
Fundus Images ◽  
Aged People ◽  
On Demand ◽  
Fundus Imaging ◽  
Specific Objective

<p>Diabetic retinopathy (DR) refers to a complication of diabetes and a prime cause of vision loss in middle-aged people. A timely screening and diagnosis process can reduce the risk of blindness. Fundus imaging is mainly preferred in the clinical analysis of DR. However; the raw fundus images are usually subjected to artifacts, noise, low and varied contrast, which is very hard to process by human visual systems and automated systems. In the existing literature, many solutions are given to enhance the fundus image. However, such approaches are particular and limited to a specific objective that cannot address multiple fundus images. This paper has presented an on-demand preprocessing frame work that integrates different techniques to address geometrical issues, random noises, and comprehensive contrast enhancement solutions. The performance of each preprocessing process is evaluated against peak signal-to-noise ratio (PSNR), and brightness is quantified in the enhanced image. The motive of this paper is to offer a flexible approach of preprocessing mechanism that can meet image enhancement needs based on different preprocessing requirements to improve the quality of fundus imaging towards early-stage diabetic retinopathy identification.</p>

scholarly journals Identification of Diabetic Retinopathy from fundus images using CNNs

2019 ◽  
Vol 9 (1) ◽  
pp. 3439-3443
Keyword(s):  
Diabetic Retinopathy ◽  
Vision Loss ◽  
Early Stage ◽  
Human Vision ◽  
Learning Approach ◽  
Fundus Images ◽  
Diabetes Treatment ◽  
Proposed Model ◽  
Fine Tune ◽  
Better Than

the Diabetic Retinopathy is the diabetes-mellitus to human vision that is the main cause of vision loss. The early stage detection of diabetic retinopathy is can play eminent role in the diabetes treatment. The fundus of retinal image is utilized to recognize the symptoms of diabetic retinopathy. Moreover, the above phenomena led us to propose this paper; here we propose segment based learning approach for identification of diabetic retinopathy. The segment based image level is required to obtain the identification of diabetic retinopathy images, the classifiers and features are equally learned from the data. Then, we adapt pre-trained CNN as the fine tune to achieve the segment level estimation of diabetic retinopathy. For identification of diabetic retinopathy, we achieve accuracy 96.97 and 98.46% at 20 and 30% and also achieve AUC (Area under Curve) 97.51 and 98.50 at 20 and 30% on the Kaggle dataset. Our proposed model outperforms much better than other models.

scholarly journals An interpretable multiple-instance approach for the detection of referable diabetic retinopathy in fundus images

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alexandros Papadopoulos ◽  
Fotis Topouzis ◽  
Anastasios Delopoulos
Keyword(s):  
Machine Learning ◽  
Diabetic Retinopathy ◽  
Vision Loss ◽  
Classification Performance ◽  
Multiple Instance Learning ◽  
Attention Mechanism ◽  
Learning System ◽  
Successful Outcome ◽  
Fundus Images ◽  
Image Patches

AbstractDiabetic retinopathy (DR) is one of the leading causes of vision loss across the world. Yet despite its wide prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for monitoring their condition. This can lead to delays in the start of treatment, thereby lowering their chances for a successful outcome. Machine learning systems that automatically detect the disease in eye fundus images have been proposed as a means of facilitating access to retinopathy severity estimates for patients in remote regions or even for complementing the human expert’s diagnosis. Here we propose a machine learning system for the detection of referable diabetic retinopathy in fundus images, which is based on the paradigm of multiple-instance learning. Our method extracts local information independently from multiple rectangular image patches and combines it efficiently through an attention mechanism that focuses on the abnormal regions of the eye (i.e. those that contain DR-induced lesions), thus resulting in a final image representation that is suitable for classification. Furthermore, by leveraging the attention mechanism our algorithm can seamlessly produce informative heatmaps that highlight the regions where the lesions are located. We evaluate our approach on the publicly available Kaggle, Messidor-2 and IDRiD retinal image datasets, in which it exhibits near state-of-the-art classification performance (AUC of 0.961 in Kaggle and 0.976 in Messidor-2), while also producing valid lesion heatmaps (AUPRC of 0.869 in the 81 images of IDRiD that contain pixel-level lesion annotations). Our results suggest that the proposed approach provides an efficient and interpretable solution against the problem of automated diabetic retinopathy grading.

Two-Tier Grading System for NPDR Severities of Diabetic Retinopathy in Retinal Fundus Images

2020 ◽  
Vol 14 ◽  
Author(s):  
Charu Bhardwaj ◽  
Shruti Jain ◽  
Meenakshi Sood
Keyword(s):  
Diabetic Retinopathy ◽  
Statistical Analysis ◽  
Early Stage ◽  
Image Feature ◽  
Grading System ◽  
Fundus Images ◽  
Fundus Image ◽  
Retinal Fundus Images ◽  
Retinal Fundus ◽  
Timely Treatment

: Diabetic Retinopathy is the leading cause of vision impairment and its early stage diagnosis relies on regular monitoring and timely treatment for anomalies exhibiting subtle distinction among different severity grades. The existing Diabetic Retinopathy (DR) detection approaches are subjective, laborious and time consuming which can only be carried out by skilled professionals. All the patents related to DR detection and diagnoses applicable for our research problem were revised by the authors. The major limitation in classification of severities lies in poor discrimination between actual lesions, background noise and other anatomical structures. A robust and computationally efficient Two-Tier DR (2TDR) grading system is proposed in this paper to categorize various DR severities (mild, moderate and severe) present in retinal fundus images. In the proposed 2TDR grading system, input fundus image is subjected to background segmentation and the foreground fundus image is used for anomaly identification followed by GLCM feature extraction forming an image feature set. The novelty of our model lies in the exhaustive statistical analysis of extracted feature set to obtain optimal reduced image feature set employed further for classification. Classification outcomes are obtained for both extracted as well as reduced feature set to validate the significance of statistical analysis in severity classification and grading. For single tier classification stage, the proposed system achieves an overall accuracy of 100% by k- Nearest Neighbour (kNN) and Artificial Neural Network (ANN) classifier. In second tier classification stage an overall accuracy of 95.3% with kNN and 98.0% with ANN is achieved for all stages utilizing optimal reduced feature set. 2TDR system demonstrates overall improvement in classification performance by 2% and 6% for kNN and ANN respectively after feature set reduction, and also outperforms the accuracy obtained by other state of the art methods when applied to the MESSIDOR dataset. This application oriented work aids in accurate DR classification for effective diagnosis and timely treatment of severe retinal ailment.

scholarly journals Possibility of Autonomous Estimation of Shiba Goat’s Estrus and Non-Estrus Behavior by Machine Learning Methods

Animals ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 771
Author(s):  
Toshiya Arakawa
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Random Forest ◽  
Markov Models ◽  
Tracking System ◽  
Video Tracking ◽  
Training Data ◽  
Support Vector ◽  
Learning Methods ◽  
Machine Learning Methods

Mammalian behavior is typically monitored by observation. However, direct observation requires a substantial amount of effort and time, if the number of mammals to be observed is sufficiently large or if the observation is conducted for a prolonged period. In this study, machine learning methods as hidden Markov models (HMMs), random forests, support vector machines (SVMs), and neural networks, were applied to detect and estimate whether a goat is in estrus based on the goat’s behavior; thus, the adequacy of the method was verified. Goat’s tracking data was obtained using a video tracking system and used to estimate whether they, which are in “estrus” or “non-estrus”, were in either states: “approaching the male”, or “standing near the male”. Totally, the PC of random forest seems to be the highest. However, The percentage concordance (PC) value besides the goats whose data were used for training data sets is relatively low. It is suggested that random forest tend to over-fit to training data. Besides random forest, the PC of HMMs and SVMs is high. However, considering the calculation time and HMM’s advantage in that it is a time series model, HMM is better method. The PC of neural network is totally low, however, if the more goat’s data were acquired, neural network would be an adequate method for estimation.

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