scholarly journals Antioxidant Activities of Imino Chromene Derivatives with Even Alkyl tail: Synthesis and Characterisation

2019 ◽  
Vol 9 (2S4) ◽  
pp. 211-213
Keyword(s):  
Nitric Oxide ◽  
Superoxide Anion ◽  
Anion Radical ◽  
Antioxidant Activities ◽  
Natural Antioxidants ◽  
Dpph Radical ◽  
Nitric Oxide Radical ◽  
Active Methylene Compounds ◽  
Active Methylene ◽  
Alkyl Tail

The reaction between substituted 4-hydroxybenzaldehyde, active methylene compounds iminochromene derivatives. Structures of the sewere established upon the basis of IR,1HNMR,13CNMR,and MASS data. Invitro, antioxidants activities oft hese compounds against superoxide anion radical, nitric oxide radical, DPPH radical and hydrogen peroxide were evaluated and compared with standard natural antioxidants ascorbicacid.

Studies on Antioxidant Activities of Breviscapine in the Cell-Free System

2008 ◽  
Vol 36 (06) ◽  
pp. 1199-1207 ◽  
Author(s):  
Min Wang ◽  
Chen Xie ◽  
Run-Lan Cai ◽  
Xiao-Hong Li ◽  
Xiu-Zhen Luo ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Antioxidant Activity ◽  
Superoxide Anion ◽  
Therapeutic Potential ◽  
Antioxidant Activities ◽  
Chinese Herb ◽  
Radical Scavenging ◽  
Free System ◽  
Nitric Oxide Radical ◽  
Ischemic Diseases

Breviscapine is a commercially produced plant extract from the Chinese herb Erigeron breviscapus. (Vant.) Hand.-Mazz., which contains 2 main flavonoids. It is widely used in clinic to treat ischemic diseases in which free radicals are considered to be the main causal factor. Our study is aimed to examine the antioxidant activity of this extract. The following assays were employed: 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, superoxide anion radical scavenging, nitric oxide radical scavenging, total anti-oxidative capacity, and antilipid peroxidation assays. Breviscapine was demonstrated to show an effective activity on scavenging DPPH, superoxide anion radicals and nitric oxide. The total antioxidative capacity of breviscapine (7.8 μg/ml to 250 μg/ml) was 1.22 to 6.74 FRAP value (× 10-5mmol). At the highest concentration of breviscapine, the inhibition extent of lipid peroxidation induced by Fe2+in rat liver homogenates was 38.5%. Because of the antioxidant activity, the present study is therefore designed to investigate the therapeutic potential of breviscapine for treatment of ischemic diseases.

scholarly journals Physicochemical and Antioxidant Properties of Acid- and Pepsin-Soluble Collagens from the Scales of Miiuy Croaker (Miichthys Miiuy)

Marine Drugs ◽  
2018 ◽  
Vol 16 (10) ◽  
pp. 394 ◽  
Author(s):  
Long-Yan Li ◽  
Yu-Qin Zhao ◽  
Yu He ◽  
Chang-Feng Chi ◽  
Bin Wang
Keyword(s):  
Amino Acid ◽  
Hydroxyl Radical ◽  
Superoxide Anion ◽  
Anion Radical ◽  
Antioxidant Properties ◽  
Superoxide Anion Radical ◽  
Type I ◽  
Dpph Radical ◽  
Soluble Collagen ◽  
Miichthys Miiuy

In this report, acid-soluble collagen (ASC-MC) and pepsin-soluble collagen (PSC-MC) were extracted from the scales of miiuy croaker (Miichthys miiuy) with yields of 0.64 ± 0.07% and 3.87 ± 0.15% of dry weight basis, respectively. ASC-MC and PSC-MC had glycine as the major amino acid with the contents of 341.8 ± 4.2 and 344.5 ± 3.2 residues/1000 residues, respectively. ASC-MC and PSC-MC had lower denaturation temperatures (32.2 °C and 29.0 °C for ASC-MC and PSC-MC, respectively) compared to mammalian collagen due to their low imino acid content (197.6 and 195.2 residues/1000 residues for ASC-MC and PSC-MC, respectively). ASC-MC and PSC-MC were mainly composed of type I collagen on the literatures and results of amino acid composition, SDS-PAGE pattern, ultraviolet (UV) and Fourier-transform infrared spectroscopy (FTIR) spectra. The maximum solubility of ASC-MC and PSC-MC was appeared at pH 1–3 and a sharp decrease in solubility was observed when the NaCl concentration was above 2%. Zeta potential studies indicated that ASC-MC and PSC-MC exhibited a net zero charge at pH 6.66 and 6.81, respectively. Furthermore, the scavenging capabilities on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, hydroxyl radical, superoxide anion radical and 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical of ASC-MC and PSC-MC were positively correlated with their tested concentration ranged from 0 to 5 mg/mL and PSC-MC showed significantly higher activity than that of ASC-MC at most tested concentrations (p < 0.05). In addition, the scavenging capability of PSC-MC on hydroxyl radical and superoxide anion radical was higher than those of DPPH radical and ABTS radical, which suggested that ASC-SC and PSC-SC might be served as hydroxyl radical and superoxide anion radical scavenger in cosmeceutical products for protecting skins from photoaging and ultraviolet damage.

Study on Scavenging Free Radical Activity with Polysaccharides Materials in Chuanxiong Based on Composite Properties of Biomaterials

2012 ◽  
Vol 583 ◽  
pp. 244-247
Author(s):  
Yong Guang Bi ◽  
Chun Chun Liu
Keyword(s):  
Free Radical ◽  
Superoxide Anion ◽  
Anion Radical ◽  
Radical Scavenging ◽  
Natural Antioxidants ◽  
Superoxide Anion Radical ◽  
Dose Effect ◽  
Spectrophotometric Detection ◽  
Free Radical Activity ◽  
Composite Properties

By using spectrophotometric detection of the Chuanxiong polysaccharides on the free radical scavenging. The results show that the Chuanxiong polysaccharides on DPPH radical, hydroxyl radical (HO•) and superoxide anion radical (•) clearance. Scavenging ability with the the Chuanxiong polysaccharide concentration increased, and showed the dose-effect relationship. Concentration of 2.0mg/mL when DPPH radicals clear the rate of 35.61%, while the rate of hydroxyl radicals and superoxide anion radical scavenging, clear the rate of 57.78% and 57.14%. Chuanxiong polysaccharide is an ideal natural antioxidants and good prospects for the development of biomedical composites.

Antioxidant Activities of Soluble Dietary Fiber Extracted from Brewers’ Spent Grain

2011 ◽  
Vol 233-235 ◽  
pp. 2824-2827 ◽  
Author(s):  
Quan Yi Fu ◽  
Xu Cong Yu ◽  
Lin Li ◽  
Guo Qin Liu ◽  
Bing Li
Keyword(s):  
Dietary Fiber ◽  
Superoxide Anion ◽  
Superoxide Radical ◽  
Antioxidant Activities ◽  
Raw Material ◽  
Dpph Radical ◽  
Brewing Industry ◽  
Soluble Dietary Fiber ◽  
Spent Grain

Brewers’ spent grain (BSG) is the most common by-product of the brewing industry, contains about 16.8% cellulose, 28.4% non-cellulosic polysaccharides and 27.8% lignin, which is a good raw material for industrial production of soluble dietary fiber (SDF).The antioxidant activity of crude dietary fiber (CDF) and grade dietary fiber (GDF) isolated from BSG was investigated in vitro. The scavenging hydroxyl radical capability of CDF and GDF was respectively reached to15.4% and 69.2% at the concentration of 0.1mg /mL. DF concentration from 0.02mg /mL to 0.1m g /mL was used. The scavenging capability of CDF and GDF to superoxide anion radical was increased from 10.68% and 12.33% to 35.78% and 78.39%. Both of the two DF showed some effect in scavenging superoxide radical and 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) radical with the concentration increase. The result showed that BSG DF can be used as a good additive with some functionality.

Note: Antioxidant Properties of Lees Produced during Sake Making Using Fugu Muscle and Fin

2003 ◽  
Vol 9 (2) ◽  
pp. 123-126 ◽  
Author(s):  
T. Nagai
Keyword(s):  
Hydroxyl Radical ◽  
Food Processing ◽  
Superoxide Anion ◽  
Anion Radical ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Superoxide Anion Radical ◽  
Industrial Wastes ◽  
Dpph Radical ◽  
Enzymatic Hydrolysates

Enzymatic hydrolysates were prepared from lees produced during sake making using fugu muscle and fin. The antioxidant properties of these hydrolysates were measured using four different methods: autoxidation test, superoxide anion radical, DPPH radical and hydroxyl radical scavenging test. The yields of enzymatic hydrolysates were around 8.0% and their protein average content 0.66 mg/mg. The lees had remarkable antioxidant properties and high superoxide anion radical and hydroxyl radical scavenging abilities in comparison with those of ascorbic acid and α-tocopherol. According to the former results, lees produced during sake making could be used as a protein source with antioxidant properties for different applications in food processing, and its use could contribute to reduce industrial wastes.

scholarly journals Alternanthera bicolor Produces Hypoglycemic Effect in Alloxan-Induced Diabetic Mice through its Antioxidant Activity

2019 ◽  
Vol 18 (1) ◽  
pp. 49-60
Author(s):  
Kousik Ahmed Khan ◽  
Manik Zahan ◽  
Fatema Zohura Talukder ◽  
Riaz Uddin ◽  
Manik Chandra Shill ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Hydrogen Peroxide ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Hypoglycemic Effect ◽  
Lipid Peroxidation Product ◽  
Diabetic Mice ◽  
Dpph Radical

The current investigation was carried out to evaluate the antioxidant properties of ethanolic extract of Alternanthera bicolor and to assess the potential hypoglycemic effect of the extract in alloxan-induced diabetic mice. HPLC-DAD method was used to determine polyphenolic compounds present in the extract. Different in vitro assays (i.e. DPPH radical scavenging activity test, reducing power test, NO radical inhibition assay and scavenging of hydrogen peroxide) were used to determine the antioxidant potential of the plant. Antidiabetic activity was evaluated in alloxan-induced diabetic mice by glucose tolerance test and standard biochemical analyses. HPLC-DAD analysis of the extract confirmed the presence of (+)-catechin hydrate, caffeic acid, quercetin and kaempferol. A. bicolor showed potent antioxidant activities in DPPH radical, hydrogen peroxide and nitric oxide scavenging assays. Moreover, A. bicolor showed potent reducing power and dose-dependent increment of total antioxidant capacity. Furthermore, the plant showed potent hypoglycemic activities in alloxan-induced diabetic mice. Ethanolic extract of the plant at doses of 200- and 400-mg/kg body weight (administered orally for 3 weeks) significantly decreased the elevated levels of blood glucose, lipid peroxidation product TBARS, hydroperoxides and nitric oxide in experimental animals. Apart from these activities, the ethanolic extract of the plant restored the reduced catalase function in liver. From this study, we can conclude that ethanolic extract of A. bicolor exhibited hypoglycemic and antioxidant activities in alloxan-induced diabetic mice. Dhaka Univ. J. Pharm. Sci. 18(1): 49-60, 2019 (June)

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