scholarly journals Differences in Risk Factors for Suicidal Ideation among Younger, Middle-Aged, and Older Adults

2021 ◽  
Vol 19 (2) ◽  
pp. 47-54
Author(s):  
Saeheon Jang
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Suicidal Ideation ◽  
Middle Aged

scholarly journals Neurocognitive markers of passive suicidal ideation in late-life depression

2020 ◽  
pp. 1-11
Author(s):  
Joshua T. Jordan ◽  
Christina F. Chick ◽  
Camarin E. Rolle ◽  
Nathan Hantke ◽  
Christine E. Gould ◽  
...  
Keyword(s):  
Older Adults ◽  
Suicidal Ideation ◽  
Cognitive Flexibility ◽  
Early Stage ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Late Life Depression ◽  
Middle Aged ◽  
Cross Sectional ◽  
Inhibitory Ability

ABSTRACT Objectives: (1) To delineate whether cognitive flexibility and inhibitory ability are neurocognitive markers of passive suicidal ideation (PSI), an early stage of suicide risk in depression and (2) to determine whether PSI is associated with volumetric differences in regions of the prefrontal cortex (PFC) in middle-aged and older adults with depression. Design: Cross-sectional study. Setting: University medical school. Participants: Forty community-dwelling middle-aged and older adults with depression from a larger study of depression and anxiety (NIMH R01 MH091342-05 PI: O’Hara). Measurements: Psychiatric measures were assessed for the presence of a DSM-5 depressive disorder and PSI. A neurocognitive battery assessed cognitive flexibility, inhibitory ability, as well as other neurocognitive domains. Results: The PSI group (n = 18) performed significantly worse on cognitive flexibility and inhibitory ability, but not on other neurocognitive tasks, compared to the group without PSI (n = 22). The group with PSI had larger left mid-frontal gyri (MFG) than the no-PSI group. There was no association between cognitive flexibility/inhibitory ability and left MFG volume. Conclusions: Findings implicate a neurocognitive signature of PSI: poorer cognitive flexibility and poor inhibitory ability not better accounted for by other domains of cognitive dysfunction and not associated with volumetric differences in the left MFG. This suggests that there are two specific but independent risk factors of PSI in middle- and older-aged adults.

scholarly journals Risk factors for depression during the COVID-19 pandemic: a longitudinal study in middle-aged and older adults

BJPsych Open ◽  
2021 ◽  
Vol 7 (5) ◽  
Author(s):  
Jamie Rutland-Lawes ◽  
Anna-Stiina Wallinheimo ◽  
Simon L. Evans
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Longitudinal Study ◽  
Regression Models ◽  
Protective Factor ◽  
Significant Risk ◽  
Living Alone ◽  
Depression Symptoms ◽  
Middle Aged ◽  
Increased Risk

Background The COVID-19 pandemic and resultant social restrictions have had widespread psychological ramifications, including a rise in depression prevalence. However, longitudinal studies on sociodemographic risk factors are lacking. Aims To quantify longitudinal changes in depression symptoms during the pandemic compared with a pre-pandemic baseline, in middle-aged and older adults, and identify the risk factors contributing to this. Method A total of 5331 participants aged ≥50 years were drawn from the English Longitudinal Study of Ageing. Self-reported depression symptoms in June/July 2020 were compared with baseline data from 2–3 years prior. Regression models investigated sociodemographic and lifestyle variables that could explain variance in change in depression. Results Within-participant depression scores increased significantly from pre-pandemic levels: 14% met the criteria for clinical depression at baseline, compared with 26% during the pandemic. Younger age, female gender, higher depression scores at baseline, living alone and having a long-standing illness were significant risk factors. Gender-stratified regression models indicated that older age was protective for women only, whereas urban living increased risk among women only. Being an alcohol consumer was a protective factor among men only. Conclusions Depression in UK adults aged ≥50 years increased significantly during the pandemic. Being female, living alone and having a long-standing illness were prominent risk factors. Younger women living in urban areas were at particularly high risk, suggesting such individuals should be prioritised for support. Findings are also informative for future risk stratification and intervention strategies, particularly if social restrictions are reimposed as the COVID-19 crisis continues to unfold.

scholarly journals Cardiovascular risk factors and memory decline in middle-aged and older adults: the English Longitudinal Study of Ageing

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Beatriz Olaya ◽  
Maria Victoria Moneta ◽  
Martin Bobak ◽  
Josep Maria Haro ◽  
Panayotes Demakakos
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Longitudinal Study ◽  
Cognitive Decline ◽  
Cardiovascular Risk Factors ◽  
Middle Aged ◽  
Memory Decline ◽  
With Memory ◽  
English Longitudinal Study

Abstract Background We investigated the association between trajectories of verbal episodic memory and burden of cardiovascular risk factors in middle-aged and older community-dwellers. Methods We analysed data from 4372 participants aged 50–64 and 3005 persons aged 65–79 years old from the English Longitudinal Study of Ageing who were repeatedly evaluated every 2 years and had six interviews of a 10-year follow-up. We measured the following baseline risk factors: diabetes, hypertension, smoking, physical inactivity and obesity to derive a cardiovascular risk factor score (CVRFs). Adjusted linear mixed effect regression models were estimated to determine the association between number of CVFRs and six repeated measurements of verbal memory scores, separately for middle-aged and older adults. Results CVRFs was not significantly associated with memory at baseline. CVFRs was significantly associated with memory decline in middle-aged (50-64y), but not in older (65-79y) participants. This association followed a dose-response pattern with increasing number of CVFRs being associated with greater cognitive decline. Comparisons between none versus some CVRFs yielded significant differences (p < 0.05). Conclusions Our findings confirm that the effect of cumulative CVRFs on subsequent cognitive deterioration is age-dependent. CVRFs are associated with cognitive decline in people aged 50–64 years, but not in those aged ≥65 years. Although modest, the memory decline associated with accumulation of cardiovascular risk factors in midlife may increase the risk of late-life dementia.

Prevalence and Risk Factors for Self-Reported Visual Impairment Among Middle-Aged and Older Adults

2005 ◽  
Vol 27 (3) ◽  
pp. 307-326 ◽  
Author(s):  
Amy Horowitz ◽  
Mark Brennan ◽  
Joann P. Reinhardt
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Visual Impairment ◽  
Middle Aged

Salmonella Infection in Middle-Aged and Older Adults: Incidence and Risk Factors from the 45 and Up Study

2016 ◽  
Vol 13 (12) ◽  
pp. 689-694 ◽  
Author(s):  
Yingxi Chen ◽  
Kathryn Glass ◽  
Bette Liu ◽  
Kirsty Hope ◽  
Martyn Kirk
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Salmonella Infection ◽  
Middle Aged

scholarly journals The association between olfactory dysfunction and cardiovascular disease and its risk factors in middle-aged and older adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daeyoung Roh ◽  
Dong-Hee Lee ◽  
Soo Whan Kim ◽  
Sung Won Kim ◽  
Byung-Guk Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Older Adults ◽  
Abdominal Obesity ◽  
Population Based ◽  
Olfactory Dysfunction ◽  
Middle Aged ◽  
Additive Interaction ◽  
History Of ◽  
Artery Disease

AbstractWhile previous studies have reported olfactory dysfunction (OD) in relation to cardiovascular disease (CVD), few population-based studies have investigated whether such associations differ by sex. The purpose of this study was to identify the association between CVD and its risk factors with OD, and the sex-associated differences within the general population. We examined 20,016 adults aged 40 and older from the Korean National Health and Nutrition Examination Survey. All subjects reported on their history of OD. CVD and its risk factors included coronary artery disease (CAD), stroke, hypertension, diabetes, obesity, abdominal obesity, and hypertriglyceridemia; logistic regression was used to analyse their associations with OD, and additive interaction was used to analyse the interaction between risk factors and sex. In males, CAD was more likely to be associated with OD (odds ratio [OR] 1.81, 95% confidence interval [CI] 1.05–3.14), whereas abdominal obesity was associated with OD in females (OR 1.39, 95% CI 1.06–1.84).Additive interaction were observed between abdominal obesity and female sex with a relative excess risk of interaction of 0.45 (95% CI 0.26–0.63). Our findings suggest the relationship between OD and CVD and its risk factors and sex-associated differences among middle-aged and older adults.

scholarly journals Prevalence of peripheral neuropathy defined by monofilament insensitivity in middle-aged and older adults in two US cohorts

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Caitlin W. Hicks ◽  
Dan Wang ◽  
B. Gwen Windham ◽  
Kunihiro Matsushita ◽  
Elizabeth Selvin
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Risk Factor ◽  
Peripheral Neuropathy ◽  
Population Based ◽  
Middle Aged ◽  
Cross Sectional ◽  
Adjusted Risk ◽  
Black And White ◽  
Artery Disease

AbstractPeripheral neuropathy is associated with substantial morbidity, but risk factors other than diabetes are largely uncharacterized. The aim of this study was to describe the prevalence and risk factors for peripheral neuropathy in adults with and without diabetes from two different population-based studies in the US. We performed a cross-sectional analysis of 5200 black and white participants from NHANES (1999–2004, age 40–85 years) and 3362 black and white participants from the ARIC Study (2016–2017, age 70–89 years) who underwent monofilament testing for peripheral neuropathy using a shared protocol. We used logistic regression to quantify age, sex, and race-adjusted risk factor associations for peripheral neuropathy among middle-aged (40–69 years) and older (≥ 70 years) adults. The age, sex, and race-adjusted prevalence of peripheral neuropathy (decreased sensation on monofilament testing) was 10.4% for middle-aged adults in NHANES, 26.8% for older adults in NHANES, and 39.2% for older adults in ARIC. Diabetes was an important risk factor, but more strongly associated with peripheral neuropathy in middle-aged (OR ~ 5 for long-standing diabetes) compared to older adults (ORs ~ 1.5–2). Male sex (ORs ~ 2), black race (ORs ~ 1.3–1.5), and greater height (ORs ~ 1.5–3) were robust risk factors for peripheral neuropathy. Other risk factors included body mass index, education, and peripheral artery disease. The burden of peripheral neuropathy defined by abnormal monofilament testing among older adults is substantial, even among adults without diabetes. Studies are needed to understand the etiology and prognosis of peripheral neuropathy in the absence of diabetes.

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