A RETROSPECTIVE STUDY OF CLINICAL AND ETIOLOGICAL PROFILES OF PATIENTS PRESENTING WITH PANCYTOPENIA

2021 ◽  
pp. 76-77
Author(s):  
kamlesh Ninama ◽  
Brajendra Kumar
Keyword(s):  
Myelodysplastic Syndrome ◽  
Aplastic Anemia ◽  
Megaloblastic Anemia ◽  
Population Data ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Presenting Symptoms ◽  
Study Population ◽  
Developed Nations ◽  
Reversible Condition

Early diagnosis and treatment are crucial in the management of pancytopenia. A retrospective cross-sectional study was undertaken at ZMCH,DAHOD. All eligible participants more than 13 years of age were included. A thorough history taking along with clinical examination and laboratory investigations were performed among the study population. Data was analyzed using SPSS version 13. The most common nding suggestive of etiology was megaloblastic anemia at 38.4%, which was more common among females. Aplastic anemia was the second most common nding at 24.6%. Other diagnoses included hypersplenism, myelodysplastic syndrome and acute leukemia. Fever and pallor were the most common presenting symptoms. Blood examinations demonstrated anisopoikilocytosis, hypersegmented neutrophils, erythroblasts, macrocytes and reticulocytes, which were found in differing proportions in the various etiological diagnoses.It is noteworthy that megaloblastic anemia, a reversible condition, is common in India compared to the higher occurrence of aplastic anemia and myelodysplastic syndrome in developed nations

scholarly journals Nutritional Trends and Practices Among 6-23 Months Old Children: A Hospital-Based Cross-Sectional Study From Bhaktapur, Nepal

2020 ◽  
Author(s):  
Sophiya Uprety ◽  
Anjita Khadka ◽  
Alina Paudyal ◽  
Dhruba Shrestha
Keyword(s):  
Young Children ◽  
Urban Areas ◽  
Dietary Diversity ◽  
Population Data ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Child Undernutrition ◽  
Nutrition Policies ◽  
Immunization Services ◽  
Study Population

Abstract Background: Child undernutrition has been a prevailing issue in country like Nepal. Though there has been progress over the decades, the burden of child undernutrition still remains unacceptably high. It is important to look at how infants and young children’s feeding practices and nutritional status are affected by nutrition transitioning in rapidly urbanizing Nepal Methods: This is a cross-sectional research design Children aged 6-23 months and their mothers visiting the hospital for regular immunization services constituted the study population. Data was collected from 305 children over four months from September 2019 to January 2020. Anthropometric measurements (weight and length) were collected of all children and their mothers/caretakers were interviewed on the IYCF practices via a semi-structured questionnaire Data was analyzed using WHO Anthro Survey Analyzer, Microsoft Excel and STATA 15.Results: Early initiation of breastfeeding was 47.9% and use of bottle was 48.5%. Minimum dietary diversity, minimum meal frequency and minimum acceptable diet were 66.2%, 79.1% and 54.4% respectively. Consumption of nutrient-poor packaged foods was 63.0% with biscuits being the most common type (52.1%) and 32.8% of the children were found to be drinking tea. Overall, 13.8% of the children were stunted, 3.9% were underweight and 1.7% were wasted while 2.3% were overweight.Conclusion: The practices related to breastfeeding and diets of young children in urban areas of Nepal are not optimal with only around half meeting the minimum standards recommended by the WHO. Therefore, there is a pressing need to wake up to the rapidly changing dietary patterns among young children through necessary urban nutrition policies and programmatic interventions, the rising adverse nutrition issues can be nipped in the bud before they get too pervasive.

scholarly journals Magnitude of Snake Bite and Drowing During Monsoon Flood in Two Districts of Bangladesh

2017 ◽  
Vol 7 (1) ◽  
pp. 3-5
Author(s):  
AM Selim Reza ◽  
SM Nurul Islam ◽  
Anirudha Ghosh ◽  
Md Ridwanur Rahman ◽  
MA Faiz ◽  
...  
Keyword(s):  
District Hospital ◽  
Population Data ◽  
Cross Sectional Study ◽  
Snake Bite ◽  
Cross Sectional ◽  
Private Hospitals ◽  
Medical College ◽  
Flood Season ◽  
The People ◽  
Study Population

Background: Snake bite and drowning is very common during the season of monsoon flood.Objective: The purpose of the present study was to see the magnitude of snake bite and drowning during monsoon flood season in two districts of Bangladesh.Methodology: This cross sectional study was conducted from May 2012 to October 2012 in the most commonly flood affected districts of Bangladesh which were Shirajgonj and Pabna. All the people living in these two districts were selected as study population. Data regarding snake bite and drowning were collected from existing health facilities at Upazila Health Complexes, district hospital, private hospitals, print media like local and national newspapers, Medical College Hospitals and police station.Result: A total number of 9 Upazila in Sirajgonj District and another 9 upazila in Pabna district were included in this study. In Sirajgonj district drowning reported were in 140 cases and snake bite was in 49 cases. Furthermore, among 49 cases of snake bite death was occurred in 7(14.3%) cases in Sirajgonj District. Interestingly Shahzadpur, Shirajgonj sadar and Ullapara were the most common reported Upazila for drowning cases which were 38(27.1%) cases, 21(15.0%) cases and 20(l4.3%) cases respectively. However, among these high prone drowning area, snake bite is reported less commonly and Kazipur was the highest reported area for snake bite which was 25(51.0%) cases. On the other hand, Pabna district drowning reported cases were in 58 and snake bite was in 62 cases. Furthermore, among 62 cases of snake bite death was occurred in 17(27.4%) cases. Sujanagar, Bera and Faridpur were the most common reported area for drowning which were 11, 10 and 9 cases respectively. However, Chatmohar was the most commonly reported by snake bite which was 20(32.3%) cases.Conclusion: Drowning is more commonly occurred in Sirajgonj district than Pabna. However, Pabna district is found a snake bite prone area.J Shaheed Suhrawardy Med Coll, 2015; 7(1):3-5

scholarly journals AETIOLOGY OF PANCYTOPENIA

2010 ◽  
Vol 17 (02) ◽  
pp. 252-256
Author(s):  
MOHAMMAD TARIQ ◽  
RABIA BASRI ◽  
NAJI ULLAH KHAN ◽  
Said Amin
Keyword(s):  
Bone Marrow ◽  
Myelodysplastic Syndrome ◽  
Aplastic Anaemia ◽  
Megaloblastic Anemia ◽  
Lymphoblastic Leukemia ◽  
Cross Sectional Study ◽  
Peripheral Blood Cell ◽  
Cross Sectional ◽  
Myelocytic Leukemia ◽  
Non Hodgkin Lymphoma

Background: Pancytopenia is a reduction in the number of each type of peripheral blood cell. Therefore the role of bone marrow examintion in diagnosis of pancytopenia is important to know etiology of pancytopenia. The objective of the study was to know the aetiology of pancytopenia. Methods: This descriptive (Cross sectional) study was carried out in Khyber teaching hospital. Fifty patients with pancytopenia were included in the study from 1st January 2008 to 30th October 2008. Full blood counts, bone marrow examinations and trephine biopsies were performed according to standard methods. Statistical packages for social science (SPSS.11) was used to analyze data. Results: Out of 50 patients, 36% were of aplastic anaemia, 16% megaloblastic anaemia, 14% myelodysplastic syndrome and 12% acute lymphoblastic leukemia (ALL), Hypersplenism in 10%, 4% non Hodgkin lymphoma (NHL) and 4% multiple myeloma, 2% each of acute myeloblastic leukemia and chronic myelocytic leukemia. All of these disorders were common in male as compared to female. Conclusions: Aplastic anaemia was the commonest cause of pancytopenia followed by megaloblastic anemia and myelodysplastic syndrome in our study.

scholarly journals Cow’s milk exposure and atopic dermatitis after six months of age

2017 ◽  
Vol 56 (6) ◽  
pp. 325
Author(s):  
Surya Jayanti Kadek ◽  
Dewi Kumara Wati Ketut ◽  
Karyana Putu Gede
Keyword(s):  
Atopic Dermatitis ◽  
Maternal Diet ◽  
Multiple Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Cow’S Milk ◽  
Milk Formula ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cow's Milk ◽  
Study Population

Background About 60% of individuals with atopic dermatitis (AD) develop their first manifestation during infancy. Cow’s milk (CM) exposure is considered to be a risk factor for AD.Objective To evaluate for an association between cow’s milk exposure and atopic dermatitis in infants > 6 months of age.  Methods This cross-sectional study consisted of subjects from a previous study and new subjects recruited in order to meet the minimum required number of subjects. Our study population comprised 120 infants, born between 1 February and 30 November, 2012 in Sanglah Hospital, Denpasar. Subjects were divided into CM and non-CM groups and analyzed for their risk of AD. Subjects were included to CM group if they were fed with cow’s milk/formula  and included to non-CM group if they were breastfeed exclusively in the first six months of life. Other possible risk factors were assessed by multivariate analysis. Results One hundred twenty subjects were enrolled and analyzed (59 in the CM and 61 in the non-CM groups). The prevalence of AD was 30%. Multiple logistic regression analysis revealed a significant association between CM exposure and AD, with odds ratio (OR) 2.37 (95%CI 1.036 to 5.420; P=0.04). In addition, maternal diet including eggs and/or cow’s milk during the breastfeeding period was significantly associated with AD in infants (OR 3.18; 95%CI 1.073 to 9.427; P=0.04).Conclusion Cow’s milk exposure is significantly associated with atopic dermatitis in infants  > six months of age. 

scholarly journals COVID-19 Vaccine Acceptance among Health Care Workers in the United States

Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 119 ◽  
Author(s):  
Rahul Shekhar ◽  
Abu Baker Sheikh ◽  
Shubhra Upadhyay ◽  
Mriganka Singh ◽  
Saket Kottewar ◽  
...  
Keyword(s):  
Final Analysis ◽  
The United States ◽  
Cross Sectional Study ◽  
Care Providers ◽  
Cross Sectional ◽  
Vaccine Acceptance ◽  
Care Workers ◽  
Vaccination Acceptance ◽  
Study Population ◽  
To Receive

Background: Acceptance of the COVID-19 vaccine will play a major role in combating the pandemic. Healthcare workers (HCWs) are among the first group to receive vaccination, so it is important to consider their attitudes about COVID-19 vaccination to better address barriers to widespread vaccination acceptance. Methods: We conducted a cross sectional study to assess the attitude of HCWs toward COVID-19 vaccination. Data were collected between 7 October and 9 November 2020. We received 4080 responses out of which 3479 were complete responses and were included in the final analysis. Results: 36% of respondents were willing to take the vaccine as soon as it became available while 56% were not sure or would wait to review more data. Only 8% of HCWs do not plan to get vaccine. Vaccine acceptance increased with increasing age, education, and income level. A smaller percentage of female (31%), Black (19%), Lantinx (30%), and rural (26%) HCWs were willing to take the vaccine as soon as it became available than the overall study population. Direct medical care providers had higher vaccine acceptance (49%). Safety (69%), effectiveness (69%), and speed of development/approval (74%) were noted as the most common concerns regarding COVID-19 vaccination in our survey.

scholarly journals Influenza vaccination and the risk of COVID-19 infection and severe illness in older adults in the United States

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kelly Huang ◽  
Shu-Wen Lin ◽  
Wang-Huei Sheng ◽  
Chi-Chuan Wang
Keyword(s):  
Immune Responses ◽  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
The United States ◽  
Cross Sectional Study ◽  
Severe Illness ◽  
Cross Sectional ◽  
Global Pandemic ◽  
Study Population ◽  
Health Database

AbstractThe coronavirus disease of 2019 (COVID-19) has caused a global pandemic and led to nearly three million deaths globally. As of April 2021, there are still many countries that do not have COVID-19 vaccines. Before the COVID-19 vaccines were developed, some evidence suggested that an influenza vaccine may stimulate nonspecific immune responses that reduce the risk of COVID-19 infection or the severity of COVID-19 illness after infection. This study evaluated the association between influenza vaccination and the risk of COVID-19 infection. We conducted a retrospective cross-sectional study with data from July 1, 2019, to June 30, 2020 with the Claims data from Symphony Health database. The study population was adults age 65 years old or older who received influenza vaccination between September 1 and December 31 of 2019. The main outcomes and measures were odds of COVID-19 infection and severe COVID-19 illness after January 15, 2020. We found the adjusted odds ratio (aOR) of COVID-19 infection risk between the influenza-vaccination group and no-influenza-vaccination group was 0.76 (95% confidence interval (CI), 0.75–0.77). Among COVID-19 patients, the aOR of developing severe COVID-19 illness was 0.72 (95% CI, 0.68–0.76) between the influenza-vaccination group and the no-influenza-vaccination group. When the influenza-vaccination group and the other-vaccination group were compared, the aOR of COVID-19 infection was 0.95 (95% CI, 0.93–0.97), and the aOR of developing a severe COVID-19 illness was 0.95 (95% CI, 0.80–1.13). The influenza vaccine may marginally protect people from COVID-19 infection.

scholarly journals Comparison of Prevalence of Periodontitis with Different Indices in Population of District Ghaziabad

2016 ◽  
Vol 04 (01) ◽  
pp. 023-030
Author(s):  
Vimal Kumar ◽  
Pallak Arora ◽  
Manish Khatri ◽  
Shivani Sharma ◽  
Sumit Malhotra ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Total Population ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sample Population ◽  
Age Group ◽  
Cross Sectional ◽  
Multi Stage ◽  
Younger Age ◽  
Study Population

Abstract Objective: To estimate the prevalence of periodontal disease with different indices. Methods & materials: The study population consisted of multistage stratified random sample of 1300 subjects from total population of district Ghaziabad. A cross-sectional study was conducted with multi stage stratified random sampling techniques to select the sample population. The subjects were divided into different age groups and the periodontal assessment was made on the basis of CPITN index and ESI Index. Results: The CPITN has shown to estimate incorrect periodontal disease prevalence because of its underestimation of the disease severity. A huge difference was noticed in the prevalence rate of periodontitis when subjects were examined with ESI index. Conclusion Periodontal disease was found to be highly prevalent in the study population and severity of disease increased with age. More number of subjects in younger age group were found to be healthy.

The Relationship between Restless Legs Syndrome and Quality of Life in Patients with Myasthenia Gravis

2019 ◽  
Vol 81 (3-4) ◽  
pp. 205-208
Author(s):  
Monica F. Ataide ◽  
Carolina da Cunha-Correia ◽  
Katia C.L. Petribú
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Restless Legs ◽  
Study Population ◽  
Clinical Conditions

Background: Restless legs syndrome (RLS) is characterized for an uncomfortable sensation in legs and an irresistible desire to move them. This disorder has been more recently recognized in patients with myasthenia gravis (MG) and can interfere with the quality of life (QOL). Objectives: The aims of this study are to describe the prevalence of RLS and its severity and influence on the QOL in patients with MG. Method: This was a cross-sectional study conducted from May to June 2016 in Recife, Brazil. A sample of 42 patients was interviewed using a sociodemographic questionnaire, MG QOL questionnaire-15 and The RLS Rating Scale. Results: RLS was present in 47.6% of patients and of these 40.5% met moderate to severe RLS criteria. Patients were 45 years on average (SD ± 14.4) and women represented 57.1% of the study population. Among patients with RSL, the quality-of-life scores were worse (p = 0.010) on average. There was no association of RLS with the duration of MG, use of immunosuppressant or clinical conditions that could mimic the occurrence of RLS. Conclusion: RLS is a prevalent condition in patients with MG, and may be severe enough to negatively impact QOL.

scholarly journals Clinical Profiles and Types of Senile Cataract Patients: Experience of 30 Cases in Bangladesh

2019 ◽  
Vol 6 (1) ◽  
pp. 38-41
Author(s):  
Shamima Sultana ◽  
AQM Omar Sharif ◽  
Inamur Rahman Choudhury ◽  
MM Ehsanul Haque ◽  
Wahida Begum
Keyword(s):  
Cross Sectional Study ◽  
Senile Cataract ◽  
Cross Sectional ◽  
Data Collection Sheet ◽  
Study Population ◽  
Computer Based ◽  
Clinical Profiles ◽  
Patients Experience ◽  
Cataract Patients ◽  
Grade Iii

Background: Senile cataract can be expressed with different clinical presentation. Objective: The purpose of the present study was to find out the clinical profiles of senile cataract patients. Methodology: This cross-sectional study was conducted at National Institute of Ophthalmology, Dhaka, Bangladesh from January 1999 to December 2000 for a period of two (02) years. Patients with senile cataract were selected for study. The details clinical profiles of the study population were recorded like types, grades of cataract and visual acuity. Data were collected on pre-designed data collection sheet, compiled and appropriate statistical analysis was done using computer based software. Result: A total number of 60 eyes of cataract patients were recruited for this study. The mean age with the standard deviation was 58.8±6.055 years. Majority of the patients were suffering from total cataract that is nuclear plus cortical plus posterior subcapsular variety which was 31(51.7%) eyes of cataract patients. Majority of the patients were grade III (amber) type of nuclear sclerosis which was 26(43.3%) eyes of cataract patients. Most of the patients were presented with PL which was 32(53.3%) eyes of cataract patients. Conclusion: In conclusion majority of the patients are suffering from total cataract with grade III (amber) type of nuclear sclerosis. Journal of Current and Advance Medical Research 2019;6(1):38-41

scholarly journals Prevalence of Hyposalivation in Patients with Systemic Lupus Erythematosus in a Brazilian Subpopulation

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Cristhiane Almeida Leite ◽  
Marcial Francis Galera ◽  
Mariano Martínez Espinosa ◽  
Paulo Ricardo Teles de Lima ◽  
Vander Fernandes ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Salivary Flow ◽  
Cross Sectional Study ◽  
Systemic Lupus ◽  
Cross Sectional ◽  
Mato Grosso ◽  
Significance Level ◽  
Factors Associated ◽  
Study Population

Background.Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease.Objective.The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated.Methods.This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from 06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance levelP<0.05.Results.The results showed that 79% of patients with systemic lupus erythematosus suffered from hyposalivation and that the disease activity and age in years were the factors that resulted in statistically significant differences.Conclusion.The activity of the disease, age >27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.

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