A COMPARATIVE ANALYSIS OF THE OCCURRENCE OF SKIN TUMORS AT A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 62-63
Author(s):  
C. Aparna ◽  
Srilekha Srilekha
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Common Risk Factor ◽  
Melanocytic Lesions ◽  
Wide Range ◽  
Genetic And Environmental Factors ◽  
Complex Organ

BACKGROUND: . The skin is a complex organ in which a wide range of neoplastic and non-neoplastic diseases can develop Exposure to sun is the most common risk factor but genetic and environmental factors , also play an important role. All ages . can be affected, however, the frequency of neoplasms increases with age Also there is an alarming increase among fair-skinned people. MATERIAL & METHODS: All the biopsies and excision specimens submitted from may 2018 to june 2020. RESULTS;Ttotal 51 specimens are studied, out of which 15 are benign and 36 are malignant. Epidermal lesions are34,adnexal lesions13,melanocytic lesions are four. CONCLUSION; females are more commonly affected than males and squamous cell carcinoma is the commonest malignancy followed by basal cell carcinoma

scholarly journals Clinicopathological profile of squamous cell carcinoma presenting in Tertiary Care Hospital, Karachi.

2020 ◽  
Vol 27 (05) ◽  
pp. 939-943
Author(s):  
Sameera Asif ◽  
Summera Kanwal ◽  
Tahera Ayub ◽  
Zafar Abbas ◽  
Batool Vazir ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Buccal Mucosa ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Stage Iv ◽  
Stage Ii ◽  
Stage Iii ◽  
Care Hospital

Objectives: Oral Squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity. The study was done with the aim to determine the clinical pattern of OSCC seen in tertiary care hospital of Karachi, Pakistan. The frequency of neck metastasis in different staging of squamous cell carcinoma was also recorded. Study Design: Retrospective study. Setting: Department of Oral & Maxillofacial Surgery Liaquat College of Medicine and Dentistry. Period: June 2013- July 2016. Material & Methods: It included 35 males and 25 females which presented with different sites and stage of squamous cell carcinoma. Clinically patients were staged as stage I, stage II, stage III and stage IV and comprised of 3, 8, 30 & 19 patients respectively. Patients presented with cancer of buccal mucosa (31 patients), retromolar region (12 patients), maxillary alveolus (8 patients), tongue (2 patients), floor of mouth (4 patients) & lip (3 patients). Right side was most common, 48 patients as compare to left side, 12 patients while lip cancers was in upper lip in all patients including commissure. Results: Total 60 patients were included in the study with the male to female ratio of 1.4:1. No significant association was seen between age and gender of the patient (p-value 0.933). Majority of patients were male involving buccal mucosa (51.67%) as the most frequently involved site followed by retromolar area (20%) and tongue (13.3%). Mean age of patients included in the study was 50.87 ± 5.53. Conclusion: Most of the cases of OSCC were seen in older patients with increased number of cases involving buccal mucosa as their primary site. Majority of the tumors were classified as stage III followed by Stage IV, Stage II and stage 1 respectively.

scholarly journals 5-year experience with vulval lesions in a tertiary care hospital: series of 115 cases

2020 ◽  
Vol 9 (12) ◽  
pp. 5001
Author(s):  
Ritu Bhat ◽  
Sachin Kolte
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Care Hospital ◽  
Labia Minora ◽  
Number Of Patients ◽  
Rare Tumours ◽  
Wide Range ◽  
Neoplastic Lesions

Background: Wide range of vulval lesions have been described with similar modes of presentation. Benign and inflammatory lesions form the major chunk. Squamous cell carcinoma is the most reported malignant entity. Aim was to review the vulval lesions received in our departmentMethods: We studied the data from the archives of the Department of Pathology for a period of 5 years from January 2014 to December 2018 for vulval biopsies and specimens sent for histopathological examination. The final diagnoses were divided into non-neoplastic, neoplastic and non- specific.Results: Age of women ranged from 22 to 86 years (mean 54.3±3.6) with the maximum number of patients between 50 to 60 years of age. Most common form of clinical presentation was an itchy white elevated lesion on the vulva (72 cases, 62.6%). The most common site for the lesions was labia minora (90 cases, 78.2%). Non neoplastic lesions were seen in 53 cases and neoplastic lesions were seen in 52 cases. There were 28 (53.8%) benign lesions while 24 cases (46.1%) were malignant. Squamous cell carcinoma was the most frequently diagnosed form accounting for 20 cases (83.3%). Rare tumours like Malignant melanoma, Merkel cell carcinoma and Neuroendocrine carcinoma formed 16.6% (n=4). Seven cases were premalignant. Two cases had non-specific histologic diagnosis showing mild chronic inflammation.Conclusions: Previous studies have reported that non-neoplastic lesions form around 70% of cases. However, in our study we found that the non-neoplastic and neoplastic lesions form equal number of cases (46%) which may be attributed to increased awareness or geographical variation.

scholarly journals Frequency of different histopathological types of esophageal cancer patients at oncology department of a tertiary care hospital in Karachi

2021 ◽  
Vol 14 (4) ◽  
pp. 161-165
Author(s):  
Zoya Sheikh ◽  
Ghulam Haider ◽  
Khalil Ahmed ◽  
Dr. Bhunisha
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Carcinoma Of The Esophagus ◽  
Histopathological Type

Background: Around the globe, carcinoma of the esophagus is the eighth most prevalent cancer with an incidence of 456,000 cases per year and is the sixth cause of cancer mortality. There are two major histological subtypes of carcinoma of the esophagus, esophageal squamous cell carcinoma and adenocarcinoma. The aim of the current study is to evaluate the frequency of different histopathological types of esophageal cancer in patients presenting at the tertiary care hospital of Karachi. Patients and methods: It was a cross-sectional study conducted at the Department of Clinical Oncology, Jinnah Postgraduate Medical Center, Karachi from March 2017 till March 2019. Two hundred and one histologically proven cases of esophageal cancer of in patients of either gender and between 15-80 years of age were included. Patients were interviewed and data regarding age, gender, education, marital status, employment status, addictions like cigarette or huqqa smoking, consumption of pan, betel nut, naswar, or gutka were recorded. Endoscopy and histology and computed tomography scan were performed. Stage, site, grade and type of tumor were noted. SPSS version 23 was used to analyze data. Mean and SD were calculated for quantitative variables. Frequency and percentage were calculated for qualitative variables. A Chi-square test was used to assess the significance between age and gender with type of EC. A p-value≤0.05 was taken as significant. Results: Mean age of the patients was 47.84. The majority of the patients had stage 2 of cancer (42.8%) and lower tumor site (62.2%) Squamous cell carcinoma was the most common histopathological type in 137 patients out of 201 (68%). The age, gender, smoking, consumption of pan, grade, site, and stage of the tumor showed a statistically significant difference when compared with esophageal squamous cell carcinoma and esophageal adenocarcinoma. Conclusion: The burden of esophageal squamous cell carcinoma is dramatically increasing in the Pakistani population and squamous cell carcinoma was the most common histopathological type.

scholarly journals Prevalence of type and etiology of lung cancer among the patients presented to a tertiary care hospital at central Kerala: a descriptive study

2018 ◽  
Vol 6 (3) ◽  
pp. 834
Author(s):  
Vadakkan Devassy Thomas ◽  
Binila Jose ◽  
Davis Kizhakkepeedika Rennis
Keyword(s):  
Lung Cancer ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Male Dominance ◽  
Care Hospital ◽  
The Right

Background: Lung cancer remains the most common cause of premature mortality in men in developing countries. This study was aimed to evaluate the type and etiological factors of lung cancer in patients presented to a tertiary care hospital of central Kerala.Methods: A retrospective descriptive study was conducted in patients who were diagnosed as lung cancer. The medical records of such patients were reviewed. The data such as age, gender, etiological risk factors and type of lung cancer were collected. Patients with incomplete reports or repeated tests, or histopathological findings were negative for lung cancers were excluded from the study.Results: Total 228 patients were included in the study with age of 64.71± 9.75. The male (198) and female (30) ratio was 6.6:1, indicated the male dominance. Among the histological types, the squamous cell carcinoma was 29% (68/228) found as the most prevalent type which is followed by adenocarcinoma 26 % (61/228). The right side (132/228) lobe was the major segment than the left side (91/228). Similarly, incidence in the central region (128/228) was more than the peripheral region (69/228). Among the right side, the upper lobe was dominant when compared to the lower or middle lobe. The lower left lobe incidence was found in 47/228 cases. Among the total, 188 cases were tobacco smokers while the remaining were nonsmokers.Conclusions: Squamous cell carcinoma with right side upper lobe of lung was prevalent among the lung cancer cases. Tobacco smoking was found to be the major etiological factor.

scholarly journals Epidemiology and pathological trends in oral squamous cell carcinoma in a local tertiary care hospital

2017 ◽  
Vol 4 (12) ◽  
pp. 4440 ◽  
Author(s):  
Hamna Gul ◽  
Farhana Asif ◽  
Iqra Ghaffar ◽  
Malik Adeel Anwar ◽  
Muhammad Arslan Tayyab ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Laboratory ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Tissue Samples

Background: Cancer archives perform a dynamic role in observing the prevalence of these cancers. The present study was carried out to study the epidemiological and pathological trends of oral squamous cell carcinoma (OSCC) in a local tertiary care hospital. Methods: Tissue samples were taken from the adult patients of both genders undergoing surgery for OSCC after an informed consent following the inclusion and exclusion criteria. Socio-demographic information was obtained along with relevant clinical, laboratory findings. Tissue samples were stained with H & E stains and were graded according to Anneroth’s system of histological grading. Data were analysed using SPSS 20.0 and a p value ≤0.05 was taken as significant. Results: The most common site for OSCC was tongue and the most common histological subtype was conventional squamous cell carcinoma, while well differentiated tumours form the largest number in the current study. Conclusions: OSCC is a growing malignancy in Pakistan with significant morbidity and mortality and the findings of the present study will be a valuable addition in the local cancer archives. 

scholarly journals The HABITS AND REASONS OF DELAYED PRESENTATION OF PATIENTS WITH ORAL CANCER AT A TERTIARY CARE HOSPITAL OF A THIRD WORLD COUNTRY

2018 ◽  
Vol 8 (3) ◽  
pp. 165-169
Author(s):  
Zohra Saleem ◽  
Syed Akbar Abbas ◽  
Falak Nadeem ◽  
Muhammad Mansoor Majeed
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Occurrence Rate ◽  
Initial Symptom ◽  
Care Hospital ◽  
Delayed Presentation

Background: Oral cancer accounts for nearly one-fifth of all cancers in males and one-tenth in females globally. Squamous cell carcinoma accounts for 90% of the oral cancer. The occurrence rate of oral cancer is higher in Sri Lanka, Bangladesh, Pakistan and India. In South Asia oral cancer constitutes 25% of all new cancer reported among males. The estimated incidence of oral cancer in Pakistan is 14.7%. Methods: A cross sectional observational study was carried out at a tertiary care hospital in Karachi with a sample of 145 patients with pathological diagnosis of squamous cell carcinoma of oral cavity. Patients were characterized into early stage (I and II) and advanced stage (III and IV), according to AJCC classification of tumors (2010). Data entry and analysis was carried out on SPSS 19. Qualitative data was expressed in percentages and results were accessed by Chi squared test. Results: The mean age was recorded 47.87 ± 12.50 years. Males participants were 63.4% and 36.6% females were incorporated in our study. More than half came with the Stage IV. 35.2% of participants became aware of their initial symptom before 6 months before pursuing any doctor. 83% patients presented with noteworthy habit of Tobacco or Chalia chewing. Bulk of the participants stated that they would have presented before if they had knowledge about the disease. 85% thought that increasing awareness of oral cancer through media may decrease the time in seeking help from qualified doctor. Conclusion: The study concludes that most of the participants presented late to the professional because of lack of knowledge about signs and symptoms of oral malignancy.

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