scholarly journals A STUDY OF DRUG UTILIZATION AND POTENTIAL DRUG-DRUG INTERACTIONS IN OUTPATIENT PHARMACY OF A TERTIARY CARE TEACHING HOSPITAL: A CROSS-SECTIONAL OBSERVATIONAL STUDY.

2020 ◽  
pp. 1-3
Author(s):  
Adit Deshmukh ◽  
Sangeeta Dabhade
Keyword(s):  
Observational Study ◽  
Drug Utilization ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Potential Drug ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Antibiotic Drug

Introduction: Drug utilization research evaluates the appropriateness of the prescriptions which is important in clinical practice. Hospital Pharmacy is the place where the data of prescriptions from all the Outpatient departments of the hospital can be gathered under one roof. Methodology: A cross-sectional, observational study was carried out in the Outpatient pharmacy of a tertiary care teaching hospital. The study was conducted over a period of 1 month on 400 prescriptions. Results: Average no of drugs per prescription was 2.40 ± 1.49. 30.25% of prescriptions contained an antibiotic. Beta lactam was the most commonly prescribed class of antibiotics, while Coamoxiclav was the most commonly prescribed antibiotic drug. 78.46% and 67.22% of the drugs were prescribed from NLEM and WHO list, respectively. Total 130 pDDIs were observed in all the 400 prescriptions surveyed, out of which 51 prescriptions were showing at least one pDDI. Conclusion: The rate of prescription of drugs from both the Essential drug lists was satisfactory. No injection was prescribed on OPD basis. Almost 87 % prescriptions were not having any potential drug-drug interaction (pDDI). All these observations highlight the rational prescription of drugs as per WHO Drug use indicators. The study highlights the need to minimize the percentage of antibiotics prescribed. Further studies are warranted to analyse the causes of Polypharmacy observed in some prescriptions in this study and to find ways to minimize it as much as possible.

scholarly journals A Cross-sectional Observational Study to Find out the Pattern of Drug Utilization and Medication Adherence of Anti-Epileptic Drugs (AEDs) among Epileptic Patients at a Tertiary Care Teaching Hospital

2021 ◽  
pp. 62-71
Author(s):  
Sunil Kardani ◽  
Rajesh Hadia ◽  
Jay Patel ◽  
Jeel Patel ◽  
Trupal Rathod ◽  
...  
Keyword(s):  
Medication Adherence ◽  
Observational Study ◽  
Drug Utilization ◽  
Sodium Valproate ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Epileptic Patients

Background: Antiepileptic drugs (AEDs) are the mainstay of the therapy for epilepsy, despite the development in recent years of new therapeutic options, such as brain stimulation or Surgery. Objective: To understand the pattern of drug utilization and medication adherence of anti-epileptic drugs (AEDs) among epileptic patients at a tertiary care teaching hospital. Methodology: A cross-sectional observational study of a total of 120 subjects receiving anti-epileptics was done. All the patients with epilepsy were prescribed with anti-epileptic drug who visited, admitted, or referred to the Department of Neurology. All inpatients and outpatients of epilepsy were screened for the study. Results: A total of 120 patients were included in our study into which (38.33%) were inpatients and (61.67%) were outpatient. The male (56%) patients were more as compared to female (44%) patients. A maximum number of patients were from the age group of 21-40 (41%) year. The majority of the patient were suffered from focal epilepsy (63%), remaining were having a generalized seizure. The highest comorbidities were found to be HTN and diabetes mellitus. Monotherapy was highly prescribed as compare to polytherapy. Among single AED, the maximum prescribed drug was Carbamazepine [30% (N=17)] followed by 25% (N=14) of phenytoin and levetiracetam 21% (N=12). In two AED Combinations, the most prescribed drugs were clobazam + Levetiracetam and Midazolam + phenytoin 12% (N=5) followed by sodium valproate + clobazam 10% (N=4). Highest combination of three AEDs that were prescribed the highest were carbamazepine + Levetiracetam + clobazam and phenytoin + phenobarbitone + sodium Valproate 20% (N=2) The highest medication adherence was found in patients who were on single AEDs and the lowest adherence was found in the patients who were on more than two AEDs. Conclusion: Antiepileptic drug monotherapy was highly prescribed as compare to polytherapy. Phenytoin was the most commonly prescribed AEDs followed by carbamazepine and highly prescribed single AEDs were found to be carbamazepine. The patients who were on single epileptic drugs showed the highest adherence as compared to the patients with more than two AEDs.

scholarly journals A PROSPECTIVE STUDY ON DRUG UTILIZATION PATTERN OF ANTIDEPRESSANTS IN NON-PSYCHIATRIC DEPARTMENTS IN A TERTIARY CARE TEACHING HOSPITAL

2019 ◽  
pp. 224-226
Author(s):  
ANCY SEBASTIAN ◽  
ANEESHA PK ◽  
JOSHWA AREECKAL ◽  
SONIYA DAVIS
Keyword(s):  
Drug Utilization ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
General Medicine ◽  
Care Hospital ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Cardiology Department ◽  
A Prospective Study

Objective: The aim of this study is to evaluate the pattern of prescription and utilization of antidepressants (ADs) for various non-psychiatric indications in department of general medicine, cardiology, surgery, gynecology, and orthopaedic of a tertiary care teaching hospital. Methods: A prospective cross-sectional unicentric drug utilization study of inpatients was carried out in a 450 bedded tertiary care hospital. The study included 200 subjects admitted for both psychiatric and non-psychiatric illness. Pediatric patients and those with a length of stay <48 h were excluded from the study. Results: Prescriptions of 200 patients were studied in which 55% were males and 45% were females. The most widely prescribed drug is alprazolam comprising 50% of the total drug consumption and is followed by clonazepam (19.5%), amitriptyline (13.5%), diazepam (9.5%), escitalopram (3.5%), lorazepam (3%), and zolpidem (0.5%). About 36% of the drugs were prescribed in the general medicine department, and 27.5% of the prescriptions were from the cardiology department. Prescriptions from surgery, orthopedics, and gynecology were 16%, 11.5%, and 9% of the total, respectively. Conclusion: ADs were found to be potentially useful for non-psychiatric indications such as peripheral and diabetic neuropathy, gastroenterological conditions, and urological conditions. No benefit was observed in insomnia and musculoskeletal conditions except for fibromyalgia. ADs were also found to improve the treatment outcome and quality of life of patients having comorbid psychiatric conditions being treated for non-psychiatric disorders.

scholarly journals Drug Utilization Study in Ophthalmology Outpatients at a Tertiary Care Teaching Hospital

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Pradeep R. Jadhav ◽  
Vijay V. Moghe ◽  
Yeshwant A. Deshmukh
Keyword(s):  
Drug Utilization ◽  
Teaching Hospital ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Prescribing Practices ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Essential Drug List ◽  
Department Of Ophthalmology

In view of the advancement in drug development and availability of new ocular therapeutics in the discipline of ophthalmology, we attempted to study the drug utilization and describe the prescribing practices of ophthalmologists in a tertiary care teaching hospital. Method. A prospective, cross-sectional, observational study was conducted on patients attending Outpatient Department of Ophthalmology for curative complaints. Prescriptions of 600 patients treated were analyzed by the WHO prescribing indicators and additional indices. Results. Analysis showed that the average number of drugs per prescription was 1.49. Percentage of drugs prescribed by generic name was 2.35%. Percentage of encounters with antibiotics was 44.83%. Percentage of drugs prescribed from National Essential drug list (NEDL)/National Formulary of India (NFI) was 19.48%. Patient's knowledge of correct dosage was 93.83%. Antimicrobial agents were the most commonly prescribed drugs followed by antiallergy drugs and ocular lubricants. Fluoroquinolones accounted for 60% of the total antimicrobial drugs, of which gatifloxacin was the most frequently prescribed fluoroquinolone. Conclusion. The study indicated an awareness of polypharmacy, but showed ample scope for improvement in encouraging the ophthalmologists to prescribe by generic name and selection of essential drugs from NEDL/NFI.

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