THE STUDY ON PRECIPITATING FACTORS OF HEPATIC ENCEPHALOPATHY IN CIRRHOTIC PATIENT IN WEST BENGAL

2021 ◽  
pp. 28-30
Author(s):  
Partha Pratim Dey ◽  
Debarshi Jana
Keyword(s):  
Hepatic Encephalopathy ◽  
Cirrhotic Patient ◽  
West Bengal ◽  
General Medicine ◽  
Electrolyte Imbalance ◽  
Precipitating Factors ◽  
Medical College ◽  
Cirrhotic Patients ◽  
One Year ◽  
Time Of Presentation

Introduction: Hepatic encephalopathy is a frequent complication and one of the most debilitating manifestations of liver diseases, severely affecting the lives of patients. Aims and objective: i. To study the precipitating factors of hepatic encephalopathy. ii. To observe the clinical manifestation at the time of presentation of hepatic encephalopathy. iii. To observe the seasonal variation of hepatic encephalopathy in cirrhotic patient. Materials and method: General Medicine, Murshidabad Medical college and R. G. Kar Medical college in West Bengal. All adult cirrhotic Patients admitted with encephalopathy in the medicine ward within the study period. One year starting from 1st Nov 2019 to 31st October 2020. Conclusion: This study found that most common precipitating factors of hepatic encephalopathy in our patients are infection, constipation electrolyte imbalance and Variceal Haemorrhage bleeding. These are potentially preventable and reversible.

RELATIONSHIP OF HYPONATREMIAAMONG PATIENTS ADMITTED IN ICU OF A TERTIARY CARE HOSPITAL IN WEST BENGAL

2021 ◽  
pp. 1-3
Author(s):  
Partha Pratim Dey ◽  
Debarshi Jana
Keyword(s):  
West Bengal ◽  
Tertiary Care ◽  
Hypovolemic Shock ◽  
General Medicine ◽  
Care Hospital ◽  
Serious Adverse Event ◽  
Medical College ◽  
One Year ◽  
Relationship Of ◽  
Paediatric Critical Care

Introduction: Hyponatremia is a serious adverse event in the paediatric critical care population is especially complex as many patients require multiple continuous infusion and excess uid volumes due to hypovolemic shock or blood pressure instability. Aim & objective:To detect hyponatremia among patients admitted in medical icu of agmc & gbph and to study its etiology. Objectives 1. To nd out the proportion of patients admitted in icu having hyponatremia. 2. To study the etiology of hyponatremia in these patients. Material & methods: One year starting from 1st Nov 2019 to 31st October 2020. All the patient admitted in the ICU; age more than 18 years, size was depend on the total admission within the study period in General Medicine, Murshidabad Medical college and R. G. Kar Medical college, West Bengal. Conclusion: We found that most common age group 41-60. It was found that male were predominance than female. It was found that 96(27.9%) patients had Hyponatremia We found that 22(6.4%) patients had Euvolemia, 49(14.2%) patients had Hypervolemia, 25(7.3%) patients had Hypovolemia and 248(72.1%) patients had normal.

Prevalence of Hepatic Encephalopathy and Its Precipitating Factors in CLD Cirrhotic Patients

2017 ◽  
Vol 10 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Anam Khalid ◽  
Amna Afsar ◽  
Mohammad Arshad ◽  
Ammarah Ghafoor ◽  
Sadaf Khalid ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Precipitating Factors ◽  
Cirrhotic Patients

scholarly journals Spectrum of hepatic encephalopathy admitted in a tertiary care center

2020 ◽  
Vol 72 ◽  
pp. 206-210
Author(s):  
Amit Soni ◽  
Shavi Nagpal ◽  
Amit Mittal
Keyword(s):  
Hepatic Encephalopathy ◽  
Hospital Mortality ◽  
Care Center ◽  
Tertiary Care ◽  
Abdominal Distension ◽  
Meld Score ◽  
Tertiary Care Center ◽  
Precipitating Factors ◽  
Cirrhotic Patients ◽  
Class C

Objectives: Few of the common symptoms for which cirrhotic patient seeks medical care are gastrointestinal bleed, abdominal distension (ascites), altered sensorium (hepatic encephalopathy [HE]), etc. This study was done to look at the spectrum of HE among cirrhotic patients admitted in a tertiary care center. Material and Methods: This hospital-based study was carried on 36 HE patients (with liver cirrhosis and age >18 years) admitted in the department of gastroenterology of a tertiary care center, between April 2019 and November 2019. Results: Constipation and infections were the two most frequent precipitating factors identified. Majority patients (77.8%) belonged to CTP Class C. In-hospital mortality was observed in seven patients. The OR was significant for infections and in-hospital mortality (OR – 28.80 and P < 0.05). A moderate positive correlation (Pearson’s correlation, r = 0.335) was seen between MELD score and in-hospital mortality among HE patients. Conclusion: A larger mass of HE patients belongs to CTP Class C. Constipation and infections are the two most common precipitating factors for HE. All HE patients who have concomitant infection and/or high MELD score should be managed on priority basis.

scholarly journals Assessment of Depression in Patients with Acute Stroke

2021 ◽  
pp. 170-173
Author(s):  
. Dayanandan ◽  
V. Bavaani
Keyword(s):  
Acute Stroke ◽  
Rating Scale ◽  
General Medicine ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Precipitating Factors ◽  
Cross Sectional ◽  
Medical College ◽  
Post Stroke Depression ◽  
Severity Of Depression

Objectives: To assess degree and severity of depression To describe the symptomatic profile of depression Analyse the relation between depression and demographic, predisposing and precipitating factors. Materials and Methods: A cross-sectional study was done on 160 subjects chosen by random sampling technique from the Department of General Medicine of Saveetha Medical College and Hospital using Montgomery-Asberg Depression Rating Scale. Results: 68% of the cases with acute stroke was assessed and found to have depression according to Montgomery-Asberg Depression Rating Scale. Conclusion: Post-Stroke Depression is expected in patients diagnosed with acute stroke.

A STUDY ON HYPONATREMIA IN CIRRHOSIS OF LIVER AND ITS PROGNOSTIC VALUE.

2021 ◽  
pp. 4-5
Author(s):  
Evuri Pramod Reddy ◽  
Pathan Fardeeba Khanam
Keyword(s):  
Liver Cirrhosis ◽  
Hepatic Encephalopathy ◽  
Hepatorenal Syndrome ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Electrolyte Imbalance ◽  
P Value ◽  
High Morbidity ◽  
Care Hospital ◽  
Cirrhotic Patients

BACKGROUND: Hyponatremia is an electrolyte imbalance that commonly occurs in hospitalized patients. In cirrhotic patients with advanced stage of disease there is release of ADHthat causes impairment in renal excretion of free 2,3 water resulting in dilutional hyponatremia in combination with renal vasoconstriction.This study was taken up to nd the prevalence of the hyponatremia and association between hyponatremia and the occurrence of major complications in patients with liver cirrhosis in a tertiary care hospital. AIMS AND OBJECTIVES 1. To study the prevalence of hyponatremia in cirrhotic patients attending a tertiary care hospital. 2 To evaluate the association between hyponatremia and complications in ci . rrhosis among patients attending a tertiary care center and its prognostic signicance. METHODS: It is a cross-sectional study done in Katuri Medical College & Hospital over a period of 13 months between june 2018 to june 2019. Patients were selected based on clinical examination,biochemical tests and ultrasound abdomen and divided into three groups as those having a sodium levels of < 130, 131 to 135 and >136 meq/l and patients having sodium levels <135 meq/l were considered hyponatremic.MELD score was calculated at the time of admission. RESULTS: There was signicant difference with respect to MELD score in three groups (p value =< 0.0001) and with respect to complications of liver cirrhosis namely portal hypertension, hepatic encephalopathy ,hepatorenal syndrome CONCLUSION: Hyponatremiain cirrhosis are associated with severe complications like hepatic encephalopathy, hepatorenal syndrome and high morbidity and mortality

Clinical Profile, Precipitating Factors and Outcome of Hepatic Encephalopathy in Patients with Liver Cirrhosis

Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 23-27
Author(s):  
Subash Bhattarai ◽  
Dipesh Karki
Keyword(s):  
Hepatic Encephalopathy ◽  
Clinical Profile ◽  
Decompensated Cirrhosis ◽  
Precipitating Factors ◽  
Early Management ◽  
Child Class ◽  
Grade Ii ◽  
Cirrhotic Patients ◽  
Class C ◽  
Upper Gastrointestinal

Introduction: Hepatic encephalopathy (HE) is characterized by reversible neuropsychological features and is observed with advanced and decompensated cirrhosis of the liver. Patients outcomes and survival depends on clinical presentation, identification of the precipitating factor, early management, and treatment of complications. This study aims to find out the clinical profile of cirrhotic patients with hepatic encephalopathy, their precipitating factors, and clinical outcomes in patients admitted at a tertiary care Teaching Hospital in Gandaki province, Nepal. Materials and Methods: An observational, cross-sectional, hospital-based prospective study comprising of 140 cirrhotic patients with encephalopathy was conducted over a study period of 18 months. Their clinical profile, precipitating factors, and outcomes during hospitalization including mortality were studied. The data analysis was done using SPSS version 20 and a P-value of ≤0.05 was considered significant. Results: Majority (36.5%) of the patients presented with Grade II HE. Upper gastrointestinal (GI) bleeding and spontaneous bacterial peritonitis were the most common precipitating factors. Inpatient mortality was 22.9%. The increased mortality rate was observed in patients with Child class C and with higher grading (Grade III and IV) of hepatic encephalopathy and in presence of more than two precipitating factors Conclusion: Most of the patients presented with Grade II HE. Upper gastrointestinal bleed and infections were the most common precipitating factors. Patients with Hepatic encephalopathy of Grades III and IV, those with CTP Child class C, and in presence of more than two precipitating factors have high mortality.

scholarly journals Detection of Precipitating Factors of Hepatic Encephalopathy in Chronic Liver Disease Patients in a Tertiary Hospital

2017 ◽  
Vol 19 (1) ◽  
pp. 10-14
Author(s):  
Md Asadul Kabir ◽  
Jewel Chowdhury ◽  
Md Anwarul Bari ◽  
Kazi Bodruddoza ◽  
Asim Kumer Saha ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Liver Disease ◽  
Hepatic Encephalopathy ◽  
Hepatitis B ◽  
Chronic Liver Disease ◽  
Disease Patient ◽  
Chronic Liver ◽  
Control Measures ◽  
Electrolyte Imbalance ◽  
Precipitating Factors

Background: Chronic liver disease (CLD) is commonly encountered by physicians in hospital practice. Hepatic encephalopathy is a serious complication of chronic liver disease, arising most commonly in those with advanced liver cirrhosis. In patients with otherwise stable cirrhosis, hepatic encephalopathy often follows clearly identifiable precipitating events. The aim of study is to find out the precipitating factors and their frequency in patients of CLD presenting with hepatic encephalopathy to prevent mortality and morbidity.Methods: This descriptive observational study was carried out to identify the precipitating factors and their frequency among 50 cases of diagnosed chronic liver disease presenting with hepatic encephalopathy at department of Medicine of Sir Salimullah Medical College & Mitford hospital, Dhaka from July 2012 to December 2012 for a period of 6 months.Results: Among 50 patients, 36 patients (72%) were male, 14 (28%) were female. Study showed that age frequency 14 (28%) were from 41-50 years and 08 (16%) were from 51-60 years, 12 (24%) >60 years of age. Out of 50 patients, the etiology of liver cirrhosis was hepatitis B virus in 28 (56%), hepatitis C virus in 4 (8%), both Hepatitis B & C in 02 (4%) Among 50 patients, 13 (26%)were in Grade-3 and 11 (22%) in Grade-2 Hepatic encephalopathy. According to Child-Pugh scoring 16 (32%) in Grade-C & 09 (18%) in Grade-B. The most common precipitating factors were identified as GI bleeding (28%), Infection (26%), mixed (16%) & unknown (20%). In this study, mortality rate was 32% most of the patients from Child-Pugh class-C.Conclusions: Commonest precipitating factors of hepatic encephalopathy in this study were upper G.I. bleeding, infection, mixed factor and electrolyte imbalance. To prevent hepatic encephalopathy caution must be exercised in putting chronic liver disease patient on diuretics. Early and effective infection control measures and better hygienic conditions in government hospitals are needed to be maintained.J MEDICINE Jan 2018; 19 (1) : 10-14

scholarly journals PROFILE OF MEDICOLEGAL AUTOPSIES OF FEMALE SUBJECTS AT A BORDER DISTRICT TERTIARY CARE CENTRE OF WEST BENGAL - A PILOT STUDY

2020 ◽  
pp. 1-3
Author(s):  
Aloke Mazumder ◽  
Umme S Faisal ◽  
Partha Pratim Mukhopadhyay ◽  
Amartya Chatterjee
Keyword(s):  
Collaborative Research ◽  
Female Subject ◽  
West Bengal ◽  
Tertiary Care ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Medical College ◽  
One Year ◽  
Female Subjects

Present study has been conducted at Department of Forensic Medicine and Toxicology, Malda Medical College, located at Malda District of West Bengal state that covers both international and state borderand having a different socio economic scenario than rest of the country which is often reflected at the pattern of medicolegal cases reported here. On the other hand, death of a female subject of medicolegal category bears definite implication on such aspects. In view of this one year autopsy based study has been conducted where out of 1685 autopsies, 562 cases were of female subjects. It has been seen that majority of unnatural deaths of females were due to effects of Hanging ( 26.87% ) , followed by Burn (19.93%) and intake of Poison (15.12% ). As per the age group is concerned, commonest age group affected was 16- 20 yrs ( 23.13%), followed by 21- 25 yr ( 14.95%). Highest incidence of such deaths took place in the month of October ( 11.21%) followed closely by August and September. Besides implementing mass awareness program on it, a collaborative research team comprising of Medicos, Judiciary and Police Authority is required to minimize such fatal outcomes of females.

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