scholarly journals MANAGEMENT STRATEGIES OF COVID-19

2020 ◽  
pp. 1-3
Author(s):  
Stuti Sharma
Keyword(s):  
Mortality Rate ◽  
Protease Inhibitors ◽  
Management Strategies ◽  
Plasma Therapy ◽  
Respiratory Condition ◽  
Randomized Controlled ◽  
The World ◽  
Treatment Alternatives ◽  
Viable Treatment

The ongoing COVID-19 pandemic clearing the globe has caused incredible concern around the world. Because of the restricted proof accessible on the elements of the infection and viable treatment alternatives accessible, extreme intense respiratory condition Covid 2 (SARS-CoV-2) has had an immense effect regarding horribleness and mortality. The monetary effect is still to be surveyed. The reason for this article is to survey the proof for the numerous treatment alternatives accessible, to think about the fate of this worldwide pandemic, and to distinguish some potential choices that could change the treatment of COVID-19. Also, this article underscores the sheer significance of repurposing a portion of the accessible antiviral and antimicrobial specialists that have for quite some time been being used in order to have a compelling and quick reaction to this inescapable pandemic and the need to direct a multicenter worldwide randomized controlled preliminary to locate a successful single antiviral operator or a mixed combination of accessible antimicrobial operators. We are as of now confronting one of the most noticeably terrible pandemics ever. Even though the mortality rate of SARS CoV 2 is not that high, yet less knowledge regarding transmission and the fear of infectivity makes it something to be scared of. Sadly, no immunization against SARS-CoV-2 or successful medication routine for COVID-19 presently exists. Medication repurposing of accessible antiviral operators may give a relief; in addition, combinations of many of antivirals and antibiotics might be useful in treating this malady. Here, we have featured a couple of accessible treatments like HCQ, Macrolides, Protease inhibitors, Convalescent Plasma therapy and the much awaited vaccines that could be compelling in treating COVID-19; in fact, various preliminaries are in progress to distinguish and affirm the viability of these specialists.

A Sustainable Approach for Organisational using Strategic Management

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Abdulla Almazrouei ◽  
◽  
Azlina Md Yassin ◽  
Keyword(s):  
Mortality Rate ◽  
Strategic Planning ◽  
Strategic Management ◽  
Crime Rate ◽  
External Environment ◽  
Police Department ◽  
Public Institutions ◽  
Abu Dhabi ◽  
The Public ◽  
The World

Strategic management have gained popularity in the public institutions to foster good delivery service to the public. The strategic planning enables organizations to establish a strategic match between the internal competency, resources and external environment. Majority of the successful organizations across the world use strategic management and planning as a tool that enables to optimize the operations and achieve maximum productivity with the resources. This paper reviewed on strategic management for organisations in Abu Dhabi especially for Abu Dhabi Police (ADP) force. It presents three strategic management theories which can be adopted by an organisation. This would help the organisation such as police department to reduce the increasing crime rate and mortality rate in UAE.

Plasma therapy a possible hope to fight against COVID-19

2020 ◽  
Author(s):  
Ravikant Piyush ◽  
Aroni Chatterjee ◽  
Shashikant Ray
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Disease ◽  
Plasma Therapy ◽  
Therapeutic Drugs ◽  
Wild Fire ◽  
The World ◽  
Short Span ◽  
Game Changer

The world is currently going through a disastrous event and a catastrophic upheaval caused by the coronavirus disease 2019 (COVID-19). The pandemic has resulted in loss of more than 150000 deaths across the globe. Originating from China and spreading across all continents within a short span of time, it has become a matter of international emergency. Different agencies are adopting diverse approaches to stop and spread of this viral disease but still now nothing confirmatory has come up. Due to lack of vaccines and proper therapeutic drugs, the disease is still spreading like wild fire without control. An Old but very promising method- the convalescent plasma therapy could be the key therapy to stop this pandemic. This method has already proven its mettle on several occasions previously and has been found to be effective in curing the pandemics induced by Ebola, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the same group of β-Coronavirus that has resulted in the above diseases. Therefore, the role of plasma therapy is being explored for treatment of this disease. In this review, we have mainly focused on the role of convalescent plasma therapy and why its use should be promoted in fight against COVID-19, as it could turn out to be a game changer.

scholarly journals Convalescent plasma therapy for COVID-19 patients: a protocol of a prospective meta-analysis of randomized controlled trials

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Lajos Szakó ◽  
Nelli Farkas ◽  
Szabolcs Kiss ◽  
Szilárd Váncsa ◽  
Noémi Zádori ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Randomized Controlled Trials ◽  
Organ Failure ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Plasma Therapy ◽  
Monthly Basis ◽  
Randomized Controlled

Abstract Background Coronavirus disease 2019 (COVID-19) is an infection with possible serious consequences. The plasma of recovered patients might serve as treatment, which we aim to assess in the form of a prospective meta-analysis focusing on mortality, multi-organ failure, duration of intensive care unit stay, and adverse events. Methods A systematic search was conducted to find relevant registered randomized controlled trials in five trial registries. A comprehensive search will be done continuously on a monthly basis in MEDLINE (via PubMed), Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of Science to find the results of previously registered randomized controlled trials. The selection will be done by two independent authors. Data extraction will be carried out by two other independent reviewers. Disagreements will be resolved by a third investigator. An update of the search of the registries and the first search of the databases will be done on the 21st of July. Data synthesis will be performed following the recommendations of the Cochrane Collaboration. In the case of dichotomous outcomes (mortality and organ failure), we will calculate pooled risk ratios with a 95% confidence interval (CI) from two-by-two tables (treatment Y/N, outcome Y/N). Data from models with multivariate adjustment (hazard ratios, odds ratio, risk ratio) will be preferred for the analysis. P less than 0.05 will be considered statistically significant. In the case of ICU stay, weighted mean difference with a 95% confidence interval will be calculated. Heterogeneity will be tested with I2, and χ2 tests. Meta-analysis will be performed if at least 3 studies report on the same outcome and population. Discussion Convalescent plasma therapy is a considerable alternative in COVID-19, which we aim to investigate in a prospective meta-analysis.

scholarly journals Ischemic Preconditioning for Liver Transplantation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2021 ◽  
pp. 1-8
Author(s):  
Lina Jakubauskiene ◽  
Matas Jakubauskas ◽  
Philipp Stiegler ◽  
Bettina Leber ◽  
Peter Schemmer ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Mortality Rate ◽  
Randomized Controlled Trials ◽  
Ischemic Preconditioning ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Meta Analysis ◽  
Graft Loss ◽  
Controlled Trials ◽  
Randomized Controlled

<b><i>Background:</i></b> In recent decades, liver transplantation (LTx) has increased the survival and quality of life of patients with end-stage organ failure. Unfortunately, LTx is limited due to the shortage of donors. A lot of effort is put into finding new ways to reduce ischemia-reperfusion injury (IRI) in liver grafts to increase the number of suitable organs procured from expanded-criteria donors (ECD). The aim of this study was to systematically review the literature reporting LTx outcomes when using ischemic preconditioning (IPC) or remote ischemic preconditioning (RIPC) to reduce IRI in liver grafts. <b><i>Methods:</i></b> A literature search was performed in the MEDLINE, Web of Science, and EMBASE databases. The following combination was used: “Liver” OR “Liver Transplantation” AND “Ischemic preconditioning” OR “occlusion” OR “clamping” OR “Pringle.” The following outcome data were retrieved: the rates of graft primary nonfunction (PNF), retransplantation, graft loss, and mortality; stay in hospital and the intensive care unit; and postoperative serum liver damage parameters. <b><i>Results:</i></b> The initial search retrieved 4,522 potentially relevant studies. After evaluating 17 full-text articles, a total of 9 randomized controlled trials (RCTs) were included (7 IPC and 2 RIPC studies) in the qualitative synthesis; the meta-analysis was only performed on the data from the IPC studies. RIPC studies had considerable methodological differences. The meta-analysis revealed the beneficial effect of IPC when comparing postoperative aspartate aminotransferase (AST) corresponding to a statistically lower mortality rate in the IPC group (odds ratio [OR] 0.51; 95% confidence interval [CI] 0.27–0.98; <i>p</i> = 0.04). <b><i>Conclusion:</i></b> IPC lowers postoperative AST levels and reduces the mortality rate; however, data on the benefits of RIPC are lacking.

scholarly journals Computational Intelligence-Based Model for Mortality Rate Prediction in COVID-19 Patients

2021 ◽  
Vol 18 (12) ◽  
pp. 6429
Author(s):  
Irfan Ullah Khan ◽  
Nida Aslam ◽  
Malak Aljabri ◽  
Sumayh S. Aljameel ◽  
Mariam Moataz Aly Kamaleldin ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Computational Intelligence ◽  
Nearest Neighbor ◽  
Gradient Boosting ◽  
K Nearest Neighbor ◽  
Detection And Identification ◽  
Proposed Model ◽  
Extreme Gradient Boosting ◽  
The World ◽  
Detection And Diagnosis

The COVID-19 outbreak is currently one of the biggest challenges facing countries around the world. Millions of people have lost their lives due to COVID-19. Therefore, the accurate early detection and identification of severe COVID-19 cases can reduce the mortality rate and the likelihood of further complications. Machine Learning (ML) and Deep Learning (DL) models have been shown to be effective in the detection and diagnosis of several diseases, including COVID-19. This study used ML algorithms, such as Decision Tree (DT), Logistic Regression (LR), Random Forest (RF), Extreme Gradient Boosting (XGBoost), and K-Nearest Neighbor (KNN) and DL model (containing six layers with ReLU and output layer with sigmoid activation), to predict the mortality rate in COVID-19 cases. Models were trained using confirmed COVID-19 patients from 146 countries. Comparative analysis was performed among ML and DL models using a reduced feature set. The best results were achieved using the proposed DL model, with an accuracy of 0.97. Experimental results reveal the significance of the proposed model over the baseline study in the literature with the reduced feature set.

scholarly journals Treating Speech Anxiety in Youth: A Randomized Controlled Microtrial Testing the Efficacy of Exposure Only versus Exposure Combined with Anxiety Management Strategies

2021 ◽  
Author(s):  
Rachel de Jong ◽  
Miriam J.J. Lommen ◽  
Marieke E. Timmerman ◽  
Wiljo J.P.J. van Hout ◽  
Rowella C.W.M. Kuijpers ◽  
...  
Keyword(s):  
Management Strategies ◽  
Speech Anxiety ◽  
Anxiety Management ◽  
Randomized Controlled

SARS-CoV-2 and Tissue Damage: Current Insights and Biomaterial-based Therapeutic Strategies

2021 ◽  
Author(s):  
Himadri Roy ◽  
Rupali Singh ◽  
Deepa Ghosh
Keyword(s):  
Mortality Rate ◽  
High Mortality ◽  
Tissue Damage ◽  
Therapeutic Strategies ◽  
The World ◽  
Rapid Transmission

The effect of SARS-CoV-2 infection on humanity has gained worldwide attention and importance due to its rapid transmission, lack of treatment and high mortality rate. While scientists across the world...

scholarly journals Importance of immunoglobulin therapy for COVID-19 patients with lymphocytopenia

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Heba K. Nabih
Keyword(s):  
Passive Immunization ◽  
Immunoglobulin Therapy ◽  
World Health ◽  
Clinical Feature ◽  
Main Body ◽  
Plasma Therapy ◽  
Rapid Spread ◽  
The World ◽  
Health Organization

Abstract Background The global coronavirus disease 2019 (COVID-19) was announced as pandemic by the World Health Organization (WHO). With the increased number of infected and dead victims daily all over the world, it becomes necessary to stop or overcome its rapid spread. Main body Although the production of vaccine or even specified effective anti-virus may take about six months to a year, intravenous immunoglobulin (IVIg) may be clinically used as a safe treatment to save and improve the quality of life of patients with a variety of immunodeficiency diseases such as lymphocytopenia, which is a common clinical feature in COVID-19. Conclusion Through the current review, it was concluded that this passive immunization may promote the immunity to better fight against the virus, so the survival of the patients could be kept longer. The efficacy of immunotherapy with IVIg would be greater if the immune IgG antibodies were collected from convalescent plasma therapy.

The Comparison of Susceptibility to SARS-CoV-2 Infection between Pediatric and Adults

2021 ◽  
Author(s):  
Milad Zandi ◽  
Saber Soltani ◽  
Mona Fani ◽  
Haniye Shafipour ◽  
Samaneh Abbasi
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Mortality Rate ◽  
Age Groups ◽  
Severe Illness ◽  
Converting Enzyme ◽  
Angiotensin Converting Enzyme 2 ◽  
The World ◽  
Smoking Susceptibility ◽  
The Relationship

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.

Sign in / Sign up

Export Citation Format

Share Document