KETONURIAAN EARLY COVID-19 SEVERITY & PROGNOSTIC MARKER? AN OBSERVATIONAL STUDY.

Ketone bodies are insignicant in the blood and urine of normal individuals. Ketoacids become important sources of metabolic energy in circumstances in which the availability of glucose is restricted, as during prolonged fasting, or when the ability to use glucose is greatly diminished, as in decompensated diabetes mellitus or any infective illness like viral or bacterial infection1.It has been found that increased utilization of glucose for CORONA virus replication. Codo et al.1 provided conclusive evidences that glycolytic ux is indispensable for SARS-CoV-2’s impact. Increased utilization of glucose for CORONA virus replication and ux results in diminished availability of glucose and therefore increased production of ketone bodies and its appearance in urine. This study assesses the level of ketonuria and disease severity and use of ketonuria as prognostic marker of COVID infection.