CHANGES IN THE PLASMA ELECTROLYTES OF FRESH WATER TELEOST FISH LABEO ROHITA EXPOSED TO SUBLETHAL CONCENTRATION OF MONOSODIUM GLUTAMATE (MSG)

2021 ◽  
pp. 32-33
Author(s):  
N. Geetha

Background: Extensive usage of MSG in numerous food products as taste enhancer, and continuous release of efuents from Feed additive industries pose a threat to aquatic organisms.MSG induced cellular damages were reported in laboratory animals but there were no reports of MSG induced stress to shes. Methods: Fish Labeo rohita exposed to sublethal concentration of MSG (150mg/L) for 15 days and plasma electrolytes level were estimated. Results: MSG is toxic to sh even in sub lethal concentration. Decrease in plasma electrolytes during initial exposure to MSG may be due to + + disturbances in the membrane permeability of gills or inhibition of Na K ATP-ase activity in the gills. Elevated plasma electrolytes in MSG exposed sh may be due to efux of ions from their tissues there by indicating severe imbalance in the osmoregulation phenomena. Conclusion: MSG is toxic to sh and caused severe osmotic imbalance. Prolonged consumption of MSG through food as well as MSG intoxicated sh may affect human health via ecological cycling and biological magnication and cause serious health hazards like susceptibility to infectious diseases and even cancer

2021 ◽  
Vol 213 (10) ◽  
pp. 65-74
Author(s):  
David Pogosyan ◽  
Roman Tyurdenev

Abstract. The purpose of the research is to develop an effective feed additive with an optimal content of raw protein in combination with flavoring additives for ducklings, which allows to increase zoo technical and economic indicators with broiler technology of fattening young animals. Research methods. A scientific and production experiment was conducted on three groups of analog ducklings from a daily age to 49 days old. The studied indicators are: the dynamics of live weight by fattening phases, absolute and average daily growth, the safety of young animals, feed conversion, slaughter indicators, the European fattening efficiency indicator, the profitability of meat production. Results. The use of compound feeds with an optimal level of protein content in combination with flavoring additives prepared on the basis of developed feed additives intended for fattening broiler ducklings in the fattening phases contributes to an increase in: live weight by 11.4 %, the safety of young animals by 3 %, feed consumption and conversion by 3.9 and 7.6 %, slaughter yield of 1.1 %, the European fattening efficiency indicator from 246 to 308 units and the profitability of meat production by 24.5 %. Scientific novelty. For the first time, a complex feed additive has been developed, which, according to the age periods of fattening, includes three varieties: “Prestart”, intended for intensive fattening of young animals from daily to 10 days of age inclusive, “Start” for ducklings from 11 to 21 days and “Finish” from 22 to 49 days. The rate of introduction of the additive is 30 % of the mass of mixed feed. The composition of the supplement includes high-protein feeds, premixes, amino acids and flavoring substances (monosodium glutamate, acetic and citric acids, a mixture of phytogenics: oregano, cinnamon, red pepper).


2016 ◽  
Vol 8 ◽  
pp. 321-327 ◽  
Author(s):  
Devan Hemalatha ◽  
Aandisamy Muthukumar ◽  
Basuvannan Rangasamy ◽  
Bojan Nataraj ◽  
Mathan Ramesh

2012 ◽  
Vol 39 (2) ◽  
pp. 413-413 ◽  
Author(s):  
Neeraj Kumar ◽  
S. B. Jadhao ◽  
N. K. Chandan ◽  
R. S. Rana

Separations ◽  
2021 ◽  
Vol 8 (11) ◽  
pp. 218
Author(s):  
Adina Lia Longodor ◽  
Aurelia Coroian ◽  
Igori Balta ◽  
Marian Taulescu ◽  
Corina Toma ◽  
...  

(1) Background: Well-known monosodium glutamate (E-621, MSG), originally used as a food flavor enhancer, was approved approximately in all countries, but the toxicity versus the safety of (MSG) are still unclear due to variable scientific toxicological reports. Moreover, it was reported to trigger elevated frequencies of nausea and headaches in humans and provide deleterious effects on laboratory animals. The objectives of the present study were to (i) estimate the possible toxic effects of the food additive MSG (ii) and the ameliorating protective effects of the dietary supplement spirulina (Spirulina platensis) on the biochemical parameters of blood and the damage produced in organs of Swiss mice after applying a supplementary daily dose of MSG for 4 weeks. (2) Methods: The present study was conducted on 20 mature Swiss mice, which were randomly organized into four groups of five Swiss mice. The treatments were (I) the control group, in which Swiss mice were fed only animal feed and drinking water; group II MSG1, which received 1 mL of MSG; group III MSG0.5, which was treated with 0.5 mL of MSG; and (IV) the group MSGS, which was treated with 1 mL of monosodium glutamate and 1 mL of spirulina (aiming to reduce the MSG toxicity). (3) Results: At the end of the experiment, Swiss mice treated with MSG demonstrated a passiveness regarding behavioral aspects. As we hypothesized, the parameters of the spirulina group reached similar values to the control group, and no histopathological observations have been found. Altogether, our findings evidenced that monosodium glutamate leads to histopathological changes in Swiss mice kidneys and caused important modifications for all biochemical parameters of the blood serum. Noticeably, the potential protective effect of Spirulina platensis was proved and was described by using the FTIR spectroscopy technique. (4) Conclusions: A diet rich in antioxidants and other plant-derived bioactive compounds may provide healthy nutrition, alleviating the potential side effects of some food additives.


2010 ◽  
Vol 26 (1-2) ◽  
pp. 91-103 ◽  
Author(s):  
P.N. Dube ◽  
B.B. Hosetti

Sodium cyanide, is highly contaminating aquatic ecosystems as a toxic pollutant, was investigated in the present study for acute toxicity on freshwater fish Labeo rohita. The toxicity tests were conducted by static renewal bioassay method on the juveniles of fish was evaluated. The LC50 value of sodium cyanide to Labeo rohita was found out to be 320 ?g l-1. One third (106 ?g l-1) and one fifth (64 ?g l-1) of the LC50 value was selected for sublethal studies. Behavioural patterns and oxygen consumption were observed in both (1/3rd and 1/5th) sublethal concentrations (1, 5, 10 and 15 days). Sodium cyanide is highly toxic to the animal tested. Fish behaved irregular, erratic, and dartic movements, by followed hyperexcitability, loss of balance, finally settles to the bottom of the test chamber. A decrease in oxygen consumption was observed in 1/3rd (11.62% and -4.52%) and 1/5th (9.11% and -2.82%) sublethal concentrations. Fish under sublethal concentration were found to be under stress but not fatal.


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