scholarly journals BACTERIAL ISOLATES AND ANTIBIOTIC SENSITIVITY PATTERNS IN CHOLEDOCHAL BILE COLLECTED DURING ERCP: A REPORT FROM CENTRAL INDIA.

2021 ◽  
pp. 13-15
Author(s):  
Mohd Talha Noor ◽  
Vishal Goyal ◽  
Praveen Vasepalli ◽  
Mayank Jain ◽  
Bhagwan Singh Thakur ◽  
...  

Temporal shifts have been known to occur in antibiotic sensitivity patterns of organisms causing cholangitis.The aim of this prospective study conducted on 100 patients of extra hepatic biliary obstruction (EHBO) was to identify the common microorganisms cultured from bile obtained during Endoscopic retrograde cholangiography and to study their local sensitivity pattern.Sixty six patients had growth in bile culture,the maximum growths amongst all micro-organisms were of Escherichia coli (40.9%) and Pseudomonas aeruginosa (40.9%). Growth rates were significantly higher in patients with non- malignant causes of biliary obstruction than those with malignant causes. Polymixins had the highest sensitivity to cultured bacteria followed by aminoglycosides and Imipenem.Study of culture & sensitivity pattern helps in deciding empirical antibiotic therapy in patients with cholangitis and it should be based on local sensitivity patterns

2018 ◽  
Vol 23 (02) ◽  
pp. 152-156
Author(s):  
Emmanuel Musa ◽  
Aliyu Kodiya ◽  
Abdullahi Kirfi ◽  
Onyekwere Nwaorgu

Introduction A common practice in the management of patients with chronic rhinosinusitis (CRS), the empirical use of antibiotics may contribute to treatment failure and to the development of antimicrobial resistance. Objective To determine the antibiotic sensitivity pattern of aerobic and anaerobic bacteria associated with CRS. Methods This was a prospective cross-sectional study in which endoscopically guided middle meatal swabs (IBM Spss, version 16.0, Chicago, IL, USA) were aseptically taken from patients diagnosed with CRS after obtaining informed consent and ethical clearance. The samples were sent to the laboratory for qualitative and semiquantitative analysis via gram stain, aerobic, anaerobic cultures and antibacterial sensitivity tests. The collected data was analyzed using SPSS for Windows, version 16 (SPSS Inc, Chicago, IL, USA). Simple statistical parameters and paired sample t-test were used, as appropriate. Results There were 74 (56.92%) bacterial growths, out of which 55 (74.32%) were aerobic and 19 (25.68%) were anaerobic isolates, from a total of 130 patients. About 13 (17.5%–18%) of these bacterial growths yielded a mixed growth of aerobic and anaerobic isolates. The most common bacterial isolates were 26 (35.14%) Staphylococcus aureus, Haemophilus influenzae 9 (12.16%), Streptococcus viridians 8 (10.81%), and Streptococcus pneumoniae 5 (6.76%). Augmentin, ciprofloxacin, and Peflacine were found to be most effective, followed by levofloxacin, Rocephin, erythromycin and Zinat in that order. Conclusion Augmentin, ciprofloxacin and Peflacine have a sensitivity of 100%, while most of the organisms show resistance to Ampiclox, amoxicillin, and Septrin.


2015 ◽  
Vol 10 (4) ◽  
pp. 1-6
Author(s):  
Nitin Insan ◽  
Anahita Hodiwala ◽  
Ravi Vashisth ◽  
Amod Yadav ◽  
Mahesh Danu

Med Phoenix ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 74-77
Author(s):  
Dipak Bhargava ◽  
Bijay Raj Pandit ◽  
Amarullah Shidiki ◽  
Ravi Shankar Gupta

Urinary tract infection is the second most common infection following respiratory tract infection. Among the outdoor and the indoor patients it is one of the common clinical state of affairs. For the effective management of this common clinical condition isolation of the common bacterial uropathogens and their antibiotic sensitivity profile is obligatory. In this present brief work an effort has been made to isolate the common bacterial uropathogen and their susceptibility pattern to the regularly used antimicrobial agents. We carried out this work in the Microbiology department of National Medical College from June 2016 to December 2016. In our study beside clean catched mid stream urine sample, catheterized urine sample and suprapubic aspirates are also collected. In our study we included a total of 516 UTI samples of patients. In our work 319 (62%) culture positive urine samples were from outpatient patient department while 197 (38%) were from inpatient department. Among both the outdoor and the indoor patient E. coli was the predominant organism followed by Klebsiella, Staphylococci, Enterococci and Pseudomonas. In our present work we found that the common bacterial isolates from the indoor patient showed higher degree resistance towards Aminopenicillin, Piperacillin, Nitrofurantoin, Ciprofloxacin and Nalidixic acid. Common bacterial uropathogens were found to be sensitive against Norfloxacin, Nitrofurantoin and Cephalosporins like Cefuroxime and Ceftazidime. It has also been found that beside E. coli other bacterial uropathogens were effective against third generation Cepahalosporins and Amikacin. This study clearly denotes that antibiotic sensitivity test should be carried out for determination of optimal treatment regimen against UTI.Med Phoenix Vol.2(1) July 2017, 74-77


Author(s):  
Vimal S. Rathod ◽  
. Kasturi ◽  
Sharmila S. Raut

Background: Infection is a major cause of morbidity and mortality among burn patients. The worldwide emergence of antimicrobial resistance among a wide variety of burn wound pathogens, particularly nosocomial isolates, limits the available therapeutic options for effective treatment of burn wound infections. The study was conducted in the department of Microbiology, Dr. S.C.G.M.C, Nanded, Maharashtra, India to determine aerobic bacterial isolates from burn wound swabs and describe their antibiogram.Methods: Two wound swabs were taken from 570 patients, cultured aerobically. The isolates were identified by standard microbiological methods and antibiotic sensitivity pattern was determined.Results: Among 570 patients, 434 (76.14%) were female and 136 (23.85%) were male. Out of the total swabs collected, 548 (96.14%) were culture positive and 36 (6.56%) were having 2 isolates. Pseudomonas aeruginosa (34.93%) was the commonest isolate followed by Staphylococcus aureus (22.77%), Klebsiella pneumoniae (13.87%), Escherichia coli (13.01%) and Coagulase negative staphylococcus (11.31%). Incidence of MRSA was 59.39% and ESBL producers were 61.46 %. Gram positive isolates were 100% sensitive to Vancomycin, Linezolid and Gram negative organisms to Imipenem.Conclusions: Routine periodic sampling of burn wounds would facilitate the selection of appropriate empirical therapy and reduce the incidence of multidrug resistant infections among burn patients.


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