UJI AKTIVITAS PERTUMBUHAN RAMBUT KOMBINASI EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) DAN DAUN LIDAH MERTUA (Sansevieria trifasciata Prain.)

ABSTRACT The frequency and quantity of hair loss problems increases which eventually leads to baldness. The use of medicinal plants today is very popular and increasingly favored by the community. Plants are efficacious as a hair grower such as pandanus leaves (Pandanus amaryllifolius Roxb.) and sansevieria leaves (Sansevieria trifasciata Prain.). The purpose of this study to determine the hair growth activity of a combination of pandanus leaves extract and sansevieria leaves. Test preparation was made by combining both extracts at 5% concentration with comparison of pandanus leaves extract and sansevieria leaves 1: 1, 2: 3 and 3: 2. The results showed that the combination of 3: 2 has the best hair growth activity. Testing of this hair growth activity is a combination extract compared to normal control, 96% ethanol and minoxidil. The result of hair growth activity showed that the combination extract had better activity than the sole extract. Key word : hair growth activity, pandanus leaves, sansevieria leaves, extract combination.

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UJI AKTIVITAS PERTUMBUHAN RAMBUT KOMBINASI EKSTRAK ETANOL DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb.) DAN DAUN LIDAH MERTUA (Sansevieria trifasciata Prain.)

Journal of Pharmacopolium ◽

10.36465/jop.v1i2.327 ◽

2018 ◽

Vol 1 (2) ◽

Author(s):

Gina Septiani A

Keyword(s):

Medicinal Plants ◽

Normal Control ◽

Hair Loss ◽

Hair Growth ◽

Test Preparation ◽

Growth Activity ◽

Pandanus Amaryllifolius

The frequency and quantity of hair loss problems increases which eventually leads to baldness. The use of medicinal plants today is very popular and increasingly favored by the community. Plants are efficacious as a hair grower such as pandanus leaves (Pandanus amaryllifolius Roxb.) and sansevieria leaves (Sansevieria trifasciata Prain.). The purpose of this study to determine the hair growth activity of a combination of pandanus leaves extract and sansevieria leaves. Test preparation was made by combining both extracts at 5% concentration with comparison of pandanus leaves extract and sansevieria leaves 1: 1, 2: 3 and 3: 2. The results showed that the combination of 3: 2 has the best hair growth activity. Testing of this hair growth activity is a combination extract compared to normal control, 96% ethanol and minoxidil. The result of hair growth activity showed that the combination extract had better activity than the sole extract. Keywords: hair growth activity, pandanus leaves, sansevieria leaves, extract combination.

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A Review on Hair Growth Regulator

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v10i5.4406 ◽

2020 ◽

Vol 10 (5) ◽

pp. 368-375

Author(s):

Manu Bharti ◽

Alankar Shrivastav ◽

M. Abid ◽

Najam Ali Khan

Keyword(s):

Side Effects ◽

Medicinal Plants ◽

Hair Loss ◽

Hair Growth ◽

Growth Promotion ◽

Promoting Effect ◽

Herbal Formulation ◽

Growth Activity ◽

Ancient Times ◽

Growth Promoting

This review presents an overview on plants identified to possess hair growth activity in various ethno-botanical studies and surveys of tradition medicinal plants. There are various causes for hair loss and the phenomenon is still not fully understood. The treatments offered include both natural or synthetic products to treat the condition of hair loss (alopecia), nonetheless natural products are continuously gaining popularity mainly due to their fewer side effects and better formulation strategies for natural product extracts. Plants have been widely used for hair growth promotion since ancient times as reported in Ayurveda, Chinese and Unani systems of medicine. This review covers information about different herbs and herbal formulation that are believed to be able to reduce the rate of hair loss and at the same time stimulate new hair growth. A focus is placed on their mechanism of action and the review also covers various isolated phytoconstituents possessing hair growth promoting effect. Keywords: Alopecia, ayurveda, hair, herbal formulation.

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Development and Evaluation of Herbal Hair Serum: A traditional way to Improve Hair Quality

The Open Dermatology Journal ◽

10.2174/1874372202115010052 ◽

2021 ◽

Vol 15 (1) ◽

pp. 52-58

Author(s):

Ruchi Tiwari ◽

Gaurav Tiwari ◽

Ajeet Yadav ◽

Vadivelan Ramachandran

Keyword(s):

Hair Loss ◽

Hair Growth ◽

Nigella Sativa ◽

Zingiber Officinale ◽

Self Defense ◽

Growth Activity ◽

Herbal Cosmetics ◽

Multiple Treatments ◽

First Time ◽

Herbal Formulations

Background: In the mammalian system, the hair follicle is known to be the most significant organ that determines appearance, gender distinction, provides intense temperature protection, and plays a role in self-defense. The younger generations have begun to suffer from extreme hair loss problems due to many lifestyle-related changes such as fatigue, anxiety, intake of junk foods, use of different hairstyling/coloring methods, etc. The loss of hair is not temporary in most cases, but it results in alopecia. Many people suffering from hair loss are in search of multiple treatments due to extreme anxiety and tension, from mythology to traditional and therapeutic healing to the use of minoxidil and finasteride. To improve hair growth and to prevent hair loss, hair root activation is required. Objective: The present study was intended to use different herbs to formulate herbal hair serum for general purposes (hair application). Methods: Crude herbs are obtained from nearby regions. In order to obtain the extract, the required part of herbs, such as Citrus sinensis peel, Zingiber officinale roots, and Linum usitatissimum seeds, Nigella sativa, and Trigonella foenum-graecum were specifically weighed and dispensed in water, boiled, allowed to cool, and then filtered. To the filtrate, castor oil and vitamin E were added. The formulated herbal hair serum was tested, and different criteria were determined and recorded in this text, such as physical appearance, viscosity, pH, homogeneity, eye sensitivity (Draize eye test), hair growth activity, hair weight, stability test, etc. Results: Prepared herbal hair serum was found to be pale brown in color with pseudoplastic behavior. The texture of the formulation was smooth and lubricative, and the pH was within the acceptable limit. Herbal hair serum revealed good hair growth as well as hair weight after application with minor sensitivity for the first time. The formulation was found to be stable for seven days. Conclusion: Herbal cosmetics are still commonly used by average citizens because of fewer side effects and greater protection and safety profile. Current research has revealed that herbal formulations are effective in enhancing hair consistency.

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Hair Growth Activity of Three Plants of the Polynesian Cosmetopoeia and Their Regulatory Effect on Dermal Papilla Cells

Molecules ◽

10.3390/molecules25194360 ◽

2020 ◽

Vol 25 (19) ◽

pp. 4360

Author(s):

Kristelle Hughes ◽

Raimana Ho ◽

Stéphane Greff ◽

Edith Filaire ◽

Edwige Ranouille ◽

...

Keyword(s):

Hair Loss ◽

Hair Growth ◽

Dermal Papilla ◽

Hair Cycle ◽

Bidens Pilosa ◽

Dermal Papilla Cells ◽

Qpcr Analysis ◽

Chemical Content ◽

Growth Activity ◽

Gene Expression Levels

Hair loss is becoming increasingly prevalent as dietary and living habits change. The search for natural products to limit hair loss has led to tapping into traditional cosmetic knowledge. We studied three plants of the Polynesian cosmetopoeia, Bidens pilosa, Calophyllum inophyllum and Fagraea berteroana, to determine their ability to promote hair growth. Their chemical content was characterized by liquid chromatography coupled to mass spectrometry (LC-MS). Their proliferative activity on dermal papilla cells (DPCs) was assessed via MTT assay and molecular targets were evaluated by RT-qPCR analysis of seven factors involved in the modulation of the hair cycle, CCND1, LEF1, DKK1, WNT5A PPARD, TGFΒ1, PPARD and RSPO2. Our results show that our extracts significantly increased proliferation of dermal papilla cells. Furthermore, LC-MS/MS analysis revealed a diversity of molecules, flavonoids, iridoids and organic acids, some known for hair-inducing properties. Finally, specific extracts and fractions of all three plants either upregulated CCND1, LEF1 and PPARD involved in stimulating hair follicle proliferation and/or lowered the gene expression levels of hair growth inhibiting factors, DKK1 and TGFB1. Our findings suggest that extracts from B. pilosa, C. inophyllum and F. berteroana are interesting candidates to stimulate hair growth.

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Ethnobotanical and Pharmacological Importance of the Herbal Plants With Anti-Hair Fall and Hair Growth Activities

Advanced Pharmacological Uses of Medicinal Plants and Natural Products - Advances in Medical Diagnosis, Treatment, and Care ◽

10.4018/978-1-7998-2094-9.ch003 ◽

2020 ◽

pp. 49-66

Author(s):

Kiran Mustafa ◽

Javaria Kanwal ◽

Sara Musaddiq ◽

Samia Khakwani

Keyword(s):

Natural Products ◽

Medicinal Plants ◽

Beneficial Effect ◽

Hair Loss ◽

Hair Growth ◽

Active Constituent ◽

Herbal Plants ◽

Natural Plants

The primary aim of this study is to access the salient herbal plants with the active constituent of potentially anti-hair fall activities. It also presents the various reasons behind hair loss ailments. As part of this study, a focus is placed on active phytochemicals within these medicinal plants or natural products in terms of various hair fall disease treatments. As natural products have a beneficial effect to minimize hair loss and have promoted the potential for new hair growth, it presents the medicinal values of natural plants in reference to safety and effectiveness for health.

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Ethnobotanical and Pharmacological Importance of the Herbal Plants With Anti-Hair Fall and Hair Growth Activities

10.4018/978-1-6684-3546-5.ch005 ◽

2022 ◽

pp. 62-75

Author(s):

Kiran Mustafa ◽

Javaria Kanwal ◽

Sara Musaddiq ◽

Samia Khakwani

Keyword(s):

Natural Products ◽

Medicinal Plants ◽

Beneficial Effect ◽

Hair Loss ◽

Hair Growth ◽

Active Constituent ◽

Herbal Plants ◽

Natural Plants

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Assessment of Nutraceutical Potential of Herbs for Promoting Hair Growth: Formulation Considerations of Herbal Hair Oil

The Open Dermatology Journal ◽

10.2174/1874372202115010078 ◽

2021 ◽

Vol 15 (1) ◽

pp. 78-83

Author(s):

Gaurav Tiwari ◽

Ruchi Tiwari

Keyword(s):

Hair Loss ◽

Hair Growth ◽

Nigella Sativa ◽

Cocos Nucifera ◽

Murraya Koenigii ◽

Hibiscus Rosa Sinensis ◽

Saponification Value ◽

Growth Activity ◽

Hair Development ◽

Herbal Cosmetics

Background: Hair loss is a relatively common occurrence that causes concern in people of all ages. In most cases, hair loss is permanent, but it can lead to alopecia. Hair root activation is necessary to improve hair development and prevent hair loss. Herbal cosmetics are increasingly widely used by the general public due to the concept of fewer adverse effects and a higher level of safety and security. Objective: The primary goal of this study is to prepare and evaluate herbal hair oil made from fresh components of various plants. Methods: Herbs were acquired from Pranveer Singh Institute of Technology's medicinal garden. Herbs were collected, dried, then ground in a mortar and pestle. Grinded herbs (Murraya koenigii, Hibiscus rosa-sinensis Linn., Nigella sativa, Trigonella foenum-graecum) were combined with 60% Cocos nucifera oil, heated, cooled, and filtered. Physical appearance, viscosity, pH, sensitivity test, hair growth activity, hair weight, antimicrobial test, stability test, and other criteria were determined and are reported in this text for the created herbal hair oil. Results: Herbal hair oil was odourless and reddish brown in appearance. Herbal hair oil had an appropriate refractive index, pH, saponification value, and specific gravity. After application, the herbal oil demonstrated Newtonian flow, as well as good hair growth and weight, with no irritation. Phytochemical screening showed the presence of ascorbic acid, sulphur and saponins. The formulation was found to be stable for 30 days. Conclusion: Conclusively, combination of effective herbs could be used to improve hair growth.

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Hair Growth in a Patient with Alopecia Areata on Tocilizumab

Skin Appendage Disorders ◽

10.1159/000516300 ◽

2021 ◽

pp. 1-5

Author(s):

Chloe J. Walker ◽

Kelly E. Flanagan ◽

James T. Pathoulas ◽

Isabel Pupo Wiss ◽

Maryanne M. Senna

Keyword(s):

Monoclonal Antibody ◽

Autoimmune Disease ◽

Hair Loss ◽

Alopecia Areata ◽

Interleukin 6 ◽

Hair Growth ◽

Posterior Uveitis ◽

Case Presentation ◽

Antibody Targeting ◽

Growth Changes

Introduction: Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ. Case Presentation: Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis. Discussion: Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth.

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