scholarly journals A Review on Hair Growth Regulator

2020 ◽  
Vol 10 (5) ◽  
pp. 368-375
Author(s):  
Manu Bharti ◽  
Alankar Shrivastav ◽  
M. Abid ◽  
Najam Ali Khan

This review presents an overview on plants identified to possess hair growth activity in various ethno-botanical studies and surveys of tradition medicinal plants. There are various causes for hair loss and the phenomenon is still not fully understood. The treatments offered include both natural or synthetic products to treat the condition of hair loss (alopecia), nonetheless natural products are continuously gaining popularity mainly due to their fewer side effects and better formulation strategies for natural product extracts. Plants have been widely used for hair growth promotion since ancient times as reported in Ayurveda, Chinese and Unani systems of medicine. This review covers information about different herbs and herbal formulation that are believed to be able to reduce the rate of hair loss and at the same time stimulate new hair growth. A focus is placed on their mechanism of action and the review also covers various isolated phytoconstituents possessing hair growth promoting effect. Keywords: Alopecia, ayurveda, hair, herbal formulation.

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2163
Author(s):  
Seyeon Park ◽  
Joomin Lee

A large number of people suffer from alopecia or hair loss worldwide. Drug-based therapies using minoxidil and finasteride for the treatment of alopecia are available, but they have shown various side effects in patients. Thus, the use of new therapeutic approaches using bioactive products to reduce the risk of anti-hair-loss medications has been emphasized. Natural products have been used since ancient times and have been proven safe, with few side effects. Several studies have demonstrated the use of plants and their extracts to promote hair growth. Moreover, commercial products based on these natural ingredients have been developed for the treatment of alopecia. Several clinical, animal, and cell-based studies have been conducted to determine the anti-alopecia effects of plant-derived biochemicals. This review is a collective study of phytochemicals with anti-alopecia effects, focusing mainly on the mechanisms underlying their hair-growth-promoting effects.


2017 ◽  
Vol 89 ◽  
pp. 438-446 ◽  
Author(s):  
Zhan-di Wang ◽  
Ying Feng ◽  
Li-yi Ma ◽  
Xian Li ◽  
Wei-feng Ding ◽  
...  

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Gina Septiani Agustien

ABSTRACT The frequency and quantity of hair loss problems increases which eventually leads to baldness. The use of medicinal plants today is very popular and increasingly favored by the community. Plants are efficacious as a hair grower such as pandanus leaves (Pandanus amaryllifolius Roxb.) and sansevieria leaves (Sansevieria trifasciata Prain.). The purpose of this study to determine the hair growth activity of a combination of pandanus leaves extract and sansevieria leaves. Test preparation was made by combining both extracts at 5% concentration with comparison of pandanus leaves extract and sansevieria leaves 1: 1, 2: 3 and 3: 2. The results showed that the combination of 3: 2 has the best hair growth activity. Testing of this hair growth activity is a combination extract compared to normal control, 96% ethanol and minoxidil. The result of hair growth activity showed that the combination extract had better activity than the sole extract. Key word : hair growth activity, pandanus leaves, sansevieria leaves, extract combination.


2020 ◽  
Vol 10 (04) ◽  
pp. 176-190
Author(s):  
Glaucia Labinas ◽  
Fernando Amaral ◽  
Valeria Maria de Souza Antunes ◽  
Maira Jardim ◽  
Leonardo Mendes Bella ◽  
...  

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Gina Septiani A

<p><em>The frequency and quantity of hair loss problems increases which eventually leads to baldness. The use of medicinal plants today is very popular and increasingly favored by the community. Plants are efficacious as a hair grower such as pandanus </em><em>leaves </em><em>(Pandanus amaryllifolius Roxb.) and sansevieria leaves (Sansevieria trifasciata Prain.). The purpose of this study to determine the hair growth activity of a combination of pandanus leaves extract and sansevieria leaves. Test preparation was made by combining both extracts at 5% concentration with comparison of pandanus lea</em><em>ves</em><em> extract and sansevieria leaves 1: 1, 2: 3 and 3: 2. The results showed that the combination of 3: 2 has the best hair growth activity. Testing of this hair growth activity is a combination extract compared to normal control, 96% ethanol and minoxidil. The result of hair growth activity showed that the combination extract had better activity than the sole extract.</em></p><p><strong> </strong></p><p><strong><em>Keywords:</em></strong><strong><em> </em></strong><em>hair growth activity, pandanus leaves, sansevieria leaves, extract combination.</em></p>


2021 ◽  
Vol 15 (1) ◽  
pp. 52-58
Author(s):  
Ruchi Tiwari ◽  
Gaurav Tiwari ◽  
Ajeet Yadav ◽  
Vadivelan Ramachandran

Background: In the mammalian system, the hair follicle is known to be the most significant organ that determines appearance, gender distinction, provides intense temperature protection, and plays a role in self-defense. The younger generations have begun to suffer from extreme hair loss problems due to many lifestyle-related changes such as fatigue, anxiety, intake of junk foods, use of different hairstyling/coloring methods, etc. The loss of hair is not temporary in most cases, but it results in alopecia. Many people suffering from hair loss are in search of multiple treatments due to extreme anxiety and tension, from mythology to traditional and therapeutic healing to the use of minoxidil and finasteride. To improve hair growth and to prevent hair loss, hair root activation is required. Objective: The present study was intended to use different herbs to formulate herbal hair serum for general purposes (hair application). Methods: Crude herbs are obtained from nearby regions. In order to obtain the extract, the required part of herbs, such as Citrus sinensis peel, Zingiber officinale roots, and Linum usitatissimum seeds, Nigella sativa, and Trigonella foenum-graecum were specifically weighed and dispensed in water, boiled, allowed to cool, and then filtered. To the filtrate, castor oil and vitamin E were added. The formulated herbal hair serum was tested, and different criteria were determined and recorded in this text, such as physical appearance, viscosity, pH, homogeneity, eye sensitivity (Draize eye test), hair growth activity, hair weight, stability test, etc. Results: Prepared herbal hair serum was found to be pale brown in color with pseudoplastic behavior. The texture of the formulation was smooth and lubricative, and the pH was within the acceptable limit. Herbal hair serum revealed good hair growth as well as hair weight after application with minor sensitivity for the first time. The formulation was found to be stable for seven days. Conclusion: Herbal cosmetics are still commonly used by average citizens because of fewer side effects and greater protection and safety profile. Current research has revealed that herbal formulations are effective in enhancing hair consistency.


2021 ◽  
pp. 118811
Author(s):  
Yingna Li ◽  
Wanwen Yu ◽  
Qingwen Cui ◽  
Jiuyue Liu ◽  
Xuechun Lu ◽  
...  

Cosmetics ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 66
Author(s):  
Hyoung Chul Choi ◽  
Gae Won Nam ◽  
Noh Hee Jeong ◽  
Bu Young Choi

Inula helenium (IH) is known to possess antifungal, anti-bacterial, anti-helminthic, and anti-proliferation activities. Caesalpinia Sappan (CS) is known to reduce inflammation and improve blood circulation. Based on their folkloric use, these plants are expected to be promising candidates for promoting hair growth and preventing hair loss. Moreover, these plants are rich sources of certain phytochemicals, which have been reported to promote hair growth. In this clinical trial, we investigate the efficacy of a scalp shampoo formulated by mixing extracts of IH and CS in preventing hair loss and promoting hair growth in patients with androgenetic alopecia. Using a phototrichogram (Folliscope 2.8, LeadM, Korea), we compared the hair density and total hair counts in patients receiving the scalp shampoo at baseline, and at 8, 16, and 24 weeks after use of the shampoo. We found a statistically significant increase in the total hair count in the test group (n = 23) after 16 and 24 weeks of using the scalp shampoo (2.17 n/cm2 ± 5.72, p < 0.05; and 4.30 n/cm2 ± 6.37, p < 0.01, respectively) as compared to the control subjects. Based on the results of this clinical study, we conclude that the IH and CS extract complex is a promising remedy for preventing hair loss and promoting hair growth.


RSC Advances ◽  
2018 ◽  
Vol 8 (73) ◽  
pp. 42170-42178 ◽  
Author(s):  
Yan Zhang ◽  
Jie-wen Wang ◽  
Fan-zhi Qu ◽  
Yu-meng Zhang ◽  
Guang-yue Su ◽  
...  

Topical use of cedrol ethanol has been reported to have a beneficial effect on hair loss.


Molecules ◽  
2020 ◽  
Vol 25 (19) ◽  
pp. 4360
Author(s):  
Kristelle Hughes ◽  
Raimana Ho ◽  
Stéphane Greff ◽  
Edith Filaire ◽  
Edwige Ranouille ◽  
...  

Hair loss is becoming increasingly prevalent as dietary and living habits change. The search for natural products to limit hair loss has led to tapping into traditional cosmetic knowledge. We studied three plants of the Polynesian cosmetopoeia, Bidens pilosa, Calophyllum inophyllum and Fagraea berteroana, to determine their ability to promote hair growth. Their chemical content was characterized by liquid chromatography coupled to mass spectrometry (LC-MS). Their proliferative activity on dermal papilla cells (DPCs) was assessed via MTT assay and molecular targets were evaluated by RT-qPCR analysis of seven factors involved in the modulation of the hair cycle, CCND1, LEF1, DKK1, WNT5A PPARD, TGFΒ1, PPARD and RSPO2. Our results show that our extracts significantly increased proliferation of dermal papilla cells. Furthermore, LC-MS/MS analysis revealed a diversity of molecules, flavonoids, iridoids and organic acids, some known for hair-inducing properties. Finally, specific extracts and fractions of all three plants either upregulated CCND1, LEF1 and PPARD involved in stimulating hair follicle proliferation and/or lowered the gene expression levels of hair growth inhibiting factors, DKK1 and TGFB1. Our findings suggest that extracts from B. pilosa, C. inophyllum and F. berteroana are interesting candidates to stimulate hair growth.


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