EVALUASI BIAYA MEDIS LANGSUNG PADA PASIEN STEVENS JOHNSON SYNDROME DI RSUP DR. SARDJITO YOGYAKARTA

2020 ◽  
Vol 10 (1) ◽  
pp. 1
Author(s):  
Darwis Darwis ◽  
Dyah Aryani Perwitasari ◽  
Sri Awalia Febriana
Keyword(s):  
Cross Sectional Study ◽  
Stevens Johnson Syndrome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Johnson Syndrome

Stevens-Johnson Syndrome (SJS) merupakan suatu reaksi hipesensitivitas akut ditandai dengan nekrosis kutaneus dan masuk 10 besar efek samping terbanyak yang dilaporkan di Indonesia sebesar 3%. Banyaknya terapi dan lama perawatan di Rumah sakit berdampak pada meningkatnya morbiditas, mortalitas dan biaya kesehatan. Tujuan penelitian untuk mengetahui biaya medis langsung pada pasien SJS akibat penggunaan obat dari perspektif rumah sakit. Metode penelitian ini merupakan jenis penelitian deskriptif yang menggunakan desain penelitian cross sectional study dengan pengambilan data retrospektif. Data yang diambil adalah pasien yang terdiagnosa SJS akibat penggunaan obat dan menjalani rawat inap di RSUP Dr. Sardjito Yogyakarta selama periode tahun 2014-2018 sesuai kriteria inklusi dan eksklusi. Hasil penelitian dari sebanyak 40 kasus pasien SJS di RSUP Dr. Sardjito Yogyakarta selama periode tahun 2014-2018. Rata-rata total biaya pada pasien SJS sebesar Rp. 14.568.255,89 ± 10.053.115,58 dengan rata-rata lama rawat inap 12,45 ± 5,69 hari. Dari penelitian ini disimpulkan bahwa rata-rata total biaya medis langsung pada SJS sebesar Rp. 14.568.255,89 ± 10.053.115,58 dan dapat menjadi beban biaya cukup tinggi bagi pasien sehingga rumah sakit dapat mengambil langkah alternatif dalam menentukan kebijakan berkaitan regimen terapi yang efektif untuk mengobati, mencegah dan menurunkan keparahan penyakit pada pasien SJS akibat penggunaan obat. 

scholarly journals Categorization of the Ocular Microbiome in Japanese Stevens–Johnson Syndrome Patients With Severe Ocular Complications

2021 ◽  
Vol 11 ◽  
Author(s):  
Mayumi Ueta ◽  
Koji Hosomi ◽  
Jonguk Park ◽  
Kenji Mizuguchi ◽  
Chie Sotozono ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Cross Sectional Study ◽  
Stevens Johnson Syndrome ◽  
Ocular Complications ◽  
Cross Sectional ◽  
Commensal Microbiota ◽  
Control Subjects ◽  
Persistent Inflammation ◽  
Johnson Syndrome ◽  
Healthy Control

The commensal microbiota is involved in a variety of diseases. Our group has noticed that patients with Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) often present with persistent inflammation of the ocular surface, even in the chronic stage, and that this inflammation is exacerbated by colonization of the mucosa by certain bacteria. However, the changes in the composition of the ocular microbiome in SJS/TEN patients with severe ocular complications (SOCs) remain to be fully investigated. Here, we conducted a cross-sectional study of 46 Japanese subjects comprising 9 healthy control subjects and 37 SJS/TEN patients with SOC. The 16S rRNA-based genetic analyses revealed that the diversity of the ocular microbiome was reduced in SJS/TEN patients with SOC compared with that in healthy control subjects. Principal coordinate analysis based on Bray–Curtis distance at the genus level revealed that the relative composition of the ocular microbiome was different in healthy control subjects and SJS/TEN patients with SOC, and that the SJS/TEN patients with SOC could be divided into four groups based on whether their microbiome was characterized by enrichment of species in genus Corynebacterium 1, Neisseriaceae uncultured, or Staphylococcus or by simultaneous enrichment in species in genera Propionibacterium, Streptococcus, Fusobacterium, Lawsonella, and Serratia. Collectively, our findings indicate that enrichment of certain bacteria at the ocular surface could be associated with ocular surface inflammation in SJS/TEN patients with SOC.

Does a Graduate Course in Fluency Disorders Make a Difference?

2010 ◽  
Vol 20 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Evelyn R. Klein ◽  
Barbara J. Amster
Keyword(s):  
Undergraduate Students ◽  
Graduate Programs ◽  
The United States ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Graduate Course ◽  
Cross Sectional ◽  
Fluency Disorders ◽  
Introductory Course ◽  
Communicative Disorders

Abstract A study by Yaruss and Quesal (2002), based on responses from 134 of 239 ASHA accredited graduate programs, indicated that approximately 25% of graduate programs in the United States allow students to earn their degree without having coursework in fluency disorders and 66% of programs allow students to graduate without clinical experience treating people who stutter (PWS). It is not surprising that many clinicians report discomfort in treating PWS. This cross-sectional study compares differences in beliefs about the cause of stuttering between freshman undergraduate students enrolled in an introductory course in communicative disorders and graduate students enrolled and in the final weeks of a graduate course in fluency disorders.

Confidence toward vaccination as reported by parents of children admitted to a tertiary care hospital in Riyadh, Saudi Arabia: A cross sectional study

Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional

Conflict Avoidance in Old Age

GeroPsych ◽  
2017 ◽  
Vol 30 (2) ◽  
pp. 61-70 ◽  
Author(s):  
Lia Oberhauser ◽  
Andreas B. Neubauer ◽  
Eva-Marie Kessler
Keyword(s):  
Social Support ◽  
Perceived Social Support ◽  
Well Being ◽  
Cross Sectional Study ◽  
Conflict Avoidance ◽  
Subjective Well Being ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adult Lifespan ◽  
Set Up

Abstract. Conflict avoidance increases across the adult lifespan. This cross-sectional study looks at conflict avoidance as part of a mechanism to regulate belongingness needs ( Sheldon, 2011 ). We assumed that older adults perceive more threats to their belongingness when they contemplate their future, and that they preventively react with avoidance coping. We set up a model predicting conflict avoidance that included perceptions of future nonbelonging, termed anticipated loneliness, and other predictors including sociodemographics, indicators of subjective well-being and perceived social support (N = 331, aged 40–87). Anticipated loneliness predicted conflict avoidance above all other predictors and partially mediated the age-association of conflict avoidance. Results suggest that belongingness regulation accounts may deepen our understanding of conflict avoidance in the second half of life.

Internalizing Behavior During the Transition from Childhood to Adolescence

2010 ◽  
Vol 26 (3) ◽  
pp. 187-193 ◽  
Author(s):  
Marc Vierhaus ◽  
Arnold Lohaus ◽  
Indra Shah
Keyword(s):  
Research Design ◽  
Internalizing Symptoms ◽  
Fourth Graders ◽  
Cross Sectional Study ◽  
Second Graders ◽  
Internalizing Behavior ◽  
Longitudinal Assessment ◽  
Sectional Study ◽  
Cross Sectional ◽  
The One

This investigation focuses on the question whether assessments of the development of internalizing behavior from childhood to adolescence are affected by the kind of research design (longitudinal versus cross-sectional). Two longitudinal samples of 432 second-graders and 366 fourth graders participated in a longitudinal study with subsequent measurements taken 1, 2, and 3 years later. A third sample consisting of 849 children covering the same range of grades participated in a cross-sectional study. The results show that the development of internalizing symptoms in girls – but not in boys – varies systematically with the research design. In girls, there is a decrease of internalizing symptoms (especially between the first two timepoints) in the longitudinal assessment, which may reflect, for example, the influence of strain during the first testing situation. Both longitudinal trajectories converge to a common trajectory from grade 2 to grade 7 when controlling for this “novelty-distress effect.” Moreover, when we control this effect, the slight but significant decrease characterizing the common trajectory becomes similar to the one obtained in the cross-sectional study. Therefore, trajectories based on longitudinal assessments may suggest more changes with regard to internalizing symptoms over time than actually take place, while trajectories based on cross-sectional data may be characterized by an increased level of internalizing symptoms. Theoretical and practical implications of these results are discussed.

Leading Distributed Workers: A Three-level Cross-sectional Study

2017 ◽  
Author(s):  
Karina Nielsen ◽  
Kevin Daniels ◽  
Rachel Nayani ◽  
Emma Donaldson-Feilder ◽  
Rachel Lewis
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional
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