scholarly journals Characterization of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Among Patients Admitted to Kenyatta National Hospital: A Retrospective Cross-Sectional Study

2017 ◽  
Vol 4 (2) ◽  
pp. 79-85 ◽  
Author(s):  
Kenneth Irungu ◽  
David Nyamu ◽  
Sylvia Opanga
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Cross Sectional Study ◽  
Stevens Johnson Syndrome ◽  
Sectional Study ◽  
National Hospital ◽  
Cross Sectional ◽  
Kenyatta National Hospital ◽  
Johnson Syndrome

EVALUASI BIAYA MEDIS LANGSUNG PADA PASIEN STEVENS JOHNSON SYNDROME DI RSUP DR. SARDJITO YOGYAKARTA

2020 ◽  
Vol 10 (1) ◽  
pp. 1
Author(s):  
Darwis Darwis ◽  
Dyah Aryani Perwitasari ◽  
Sri Awalia Febriana
Keyword(s):  
Cross Sectional Study ◽  
Stevens Johnson Syndrome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Johnson Syndrome

Stevens-Johnson Syndrome (SJS) merupakan suatu reaksi hipesensitivitas akut ditandai dengan nekrosis kutaneus dan masuk 10 besar efek samping terbanyak yang dilaporkan di Indonesia sebesar 3%. Banyaknya terapi dan lama perawatan di Rumah sakit berdampak pada meningkatnya morbiditas, mortalitas dan biaya kesehatan. Tujuan penelitian untuk mengetahui biaya medis langsung pada pasien SJS akibat penggunaan obat dari perspektif rumah sakit. Metode penelitian ini merupakan jenis penelitian deskriptif yang menggunakan desain penelitian cross sectional study dengan pengambilan data retrospektif. Data yang diambil adalah pasien yang terdiagnosa SJS akibat penggunaan obat dan menjalani rawat inap di RSUP Dr. Sardjito Yogyakarta selama periode tahun 2014-2018 sesuai kriteria inklusi dan eksklusi. Hasil penelitian dari sebanyak 40 kasus pasien SJS di RSUP Dr. Sardjito Yogyakarta selama periode tahun 2014-2018. Rata-rata total biaya pada pasien SJS sebesar Rp. 14.568.255,89 ± 10.053.115,58 dengan rata-rata lama rawat inap 12,45 ± 5,69 hari. Dari penelitian ini disimpulkan bahwa rata-rata total biaya medis langsung pada SJS sebesar Rp. 14.568.255,89 ± 10.053.115,58 dan dapat menjadi beban biaya cukup tinggi bagi pasien sehingga rumah sakit dapat mengambil langkah alternatif dalam menentukan kebijakan berkaitan regimen terapi yang efektif untuk mengobati, mencegah dan menurunkan keparahan penyakit pada pasien SJS akibat penggunaan obat. 

Genomic, Metagenomic and Transcriptomic Characterization of the Clinical Forms of COVID-19: A Comparative Cross-Sectional Study

2020 ◽  
Author(s):  
Christophe Rodriguez ◽  
Nicolas de Prost ◽  
Slim Fourati ◽  
Claudie Lamoureux ◽  
Guillaume Gricourt ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Clinical Forms

scholarly journals Characteristics, Management, and Case-Fatality of Patients Hospitalized for Stroke with a Diagnosis of COVID-19 in France

2021 ◽  
pp. 1-7
Author(s):  
Amélie Gabet ◽  
Clémence Grave ◽  
Edouard Chatignoux ◽  
Philippe Tuppin ◽  
Yannick Béjot ◽  
...  
Keyword(s):  
Case Fatality ◽  
Cross Sectional Study ◽  
Primary Diagnosis ◽  
Index Hospitalization ◽  
Sectional Study ◽  
Stroke Patients ◽  
National Hospital ◽  
Cross Sectional ◽  
Increased Risk ◽  
Systèmes D’Information

<b><i>Introduction:</i></b> COVID-19 was found to be associated with an increased risk of stroke. This study aimed to compare characteristics, management, and outcomes of hospitalized stroke patients with or without a hospital diagnosis of CO­VID-19 at a nationwide scale. <b><i>Methods:</i></b> This is a cross-sectional study on all French hospitals covering the entire French population using the French national hospital discharge databases (<i>Programme de Médicalisation des Systèmes d’Information</i>, included in the <i>Système National des Données de Santé</i>). All patients hospitalized for stroke between 1 January and 14 June 2020 in France were selected. A diagnosis of COVID-19 was searched for during the index hospitalization for stroke or in a prior hospitalization that had occurred after 1 January 2020. <b><i>Results:</i></b> Among the 56,195 patients hospitalized for stroke, 800 (1.4%) had a concomitant COVID-19 diagnosis. Inhospital case-fatality rates were higher in stroke patients with COVID-19, particularly for patients with a primary diagnosis of COVID-19 (33.2%), as compared to patients hospitalized for stroke without CO­VID-19 diagnosis (14.1%). Similar findings were observed for 3-month case-fatality rates adjusted for age and sex that reached 41.7% in patients hospitalized for stroke with a concomitant primary diagnosis of COVID-19 versus 20.0% in strokes without COVID-19. <b><i>Conclusion:</i></b> Patients hospitalized for stroke with a concomitant COVID-19 diagnosis had a higher inhospital and 3 months case-fatality rates compared to patients hospitalized for stroke without a COVID-19 diagnosis. Further research is needed to better understand the excess of mortality related to these cases.

Evaluation of Supratentorial Brain Neoplasms - A Cross Sectional Study from a Tertiary Care Hospital, Surendranagar, Gujarat

2021 ◽  
Vol 8 (26) ◽  
pp. 2253-2259
Author(s):  
Mohit B. Gor ◽  
Kuldeepsinh D. Mori ◽  
Mehul N. Bavishi ◽  
Nirmala C. Chudasama ◽  
Jaypalsinh D. Barad ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Brain Tumours ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Resonance Imaging ◽  
Cross Sectional ◽  
Multiplanar Imaging ◽  
Higher Sensitivity

BACKGROUND Brain tumours represents 1.7 % of all cancers and contributes 1.8 % of all cancer deaths. Of all the brain tumours, 80 % are supratentorial.1 Magnetic resonance imaging (MRI) is an important modality, having higher sensitivity for detecting intracranial pathology. Multiplanar imaging is possible with MRI which helps in detection, localization and characterization of the lesion. MRI examination has helped in early diagnosis, accurate localization of the tumour, with prompt initiation of appropriate medical or surgical therapy. Recent advances like magnetic resonance (MR) spectroscopy, MR fluoroscopy with stereotactic guided biopsy have revolutionized the role of MRI in study of intracranial tumours. METHODS A cross sectional study of 75 patients was done by Siemens Essenza 1.5T MRI from June 2018 to June 2020 using dedicated head coil. RESULTS In our study, most of the patients were between 31 - 60 years of age (39 % of all patients) with the largest group between 31 - 40 years (20 % of all patients). Out of 75 cases of supratentorial neoplasms, 47 (72 %) were intra-axial lesions, 15 (23 %) were extra-axial lesions and 3 (5 %) were intra ventricular lesions. In this study, 69 % of the lesions were solitary and 31 % were multiple. Most of patients (89 %) showed some enhancement, most common being heterogeneous/inhomogeneous enhancement. Commonest type of supratentorial neoplasms were metastases comprising 29 % of this study. CONCLUSIONS Magnetic resonance imaging is an important modality, having higher sensitivity for detecting intracranial pathology. Multiplanar imaging is possible with MRI which helps in early detection, localization and characterization of the lesion. Metastasis is the most common supratentorial tumour in this study followed by meningioma. Intra-axial tumours are more common than extra-axial tumours in this study. KEYWORDS MRI, Metastasis, Glioma, Meningioma

scholarly journals Characterization of the Subgingival Cultivable Microbiota in Patients with Different Stages of Periodontitis in Spain and Colombia. A Cross-Sectional Study

2021 ◽  
Vol 9 (9) ◽  
pp. 1940
Author(s):  
Roquelina Pianeta ◽  
Margarita Iniesta ◽  
Diana Marcela Castillo ◽  
Gloria I. Lafaurie ◽  
Mariano Sanz ◽  
...  
Keyword(s):  
Bacterial Species ◽  
Fusobacterium Nucleatum ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Campylobacter Rectus ◽  
Parvimonas Micra ◽  
Final Sample

The objective was to characterize and compare the subgingival microbiota in patients diagnosed according to the World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions 2018. For this cross-sectional study, Spanish and Colombian subjects (characterized as health/gingivitis, periodontitis in stages I-II or stages III-IV) were clinically assessed, and subgingival samples were taken and processed by culture. The comparisons among patients with periodontal status (and between countries) was made using Mann–Whitney, Kruskal–Wallis, ANOVA and chi-square tests. The final sample consisted of 167 subjects. Eikenella corrodens and Parvimonas micra were more frequently detected in health/gingivitis and Porphyromonas gingivalis in periodontitis (p < 0.05). Higher total counts were observed in Colombia (p = 0.036). In Spain, significantly higher levels of P. gingivalis and Campylobacter rectus were observed, and of Tannerella forsythia, P. micra, Prevotella intermedia, Fusobacterium nucleatum, Actinomyces odontolyticus and Capnocytophaga spp. in Colombia (p < 0.001). P. micra was more prevalent in health/gingivitis and stage I-II periodontitis in Colombia, and P. gingivalis in all periodontitis groups in Spain (p < 0.05). As conclusions, significant differences were detected in the microbiota between health/gingivitis and periodontitis, with minor differences between stages of periodontitis. Differences were also relevant between countries, with Colombia showing larger counts and variability of bacterial species.

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