scholarly journals Atopic dermatitis in preschool children: prevalence, clinical and allergic characteristics and risk factors

2018 ◽  
Vol 15 (1) ◽  
pp. 55-62 ◽  
Author(s):  
N V Shakhova ◽  
E M Kamaltynova ◽  
U F Lobanov ◽  
T S Ardatova

Background. Information on atopic dermatitis (AD) epidemiology in preschool children is scarce. Objectives. To estimate the prevalence, clinical, allergological characteristics and risk factors of AD in preschool children. Materials and methods. 5156 children aged 3-6 years old living in the Altai Territory participated in the study. The study included a screening and clinical phases. At the screening stage of the study the prevalence of AD was evaluated using the Russian version of the ISAAC questionnaire, risk factors were evaluated using the additional questionnaire. At the clinical stage diagnosis of AD was verified by allergists. Results. The prevalence of atopic dermatitis was 9,9%. 73,8% of children had mild AD; 58,5% of children were sensitized: 25 (15,6%) to food allergens - 12 (7,2%) to egg, 12 (7,2%) to cow’s milk, 6 (3,6%) to wheat flour and 8 (4,9%) to fish. The most important inhaled allergens were house dust mites, the sensitivity to them was diagnosed in 44 (26,8%) children. The family anamnesis of allergic diseases increases risk of development of AD by 5 times (OR=5,7; 95% CI=4,1-7,9; p

2017 ◽  
Vol 14 (1) ◽  
pp. 41-46
Author(s):  
N V Shakhova ◽  
E M Kamaltynova ◽  
U F Lobanov ◽  
T S Ardatova ◽  
K S Nikolaeva ◽  
...  

Objectives. To estimate the prevalence of current asthma-like symptoms and current allergic diseases among preschool children and to determine the risk factors. Materials and methods. Cross-sectional study included children aged 3-6 years. The study was conducted in 5 towns of Altai region. Prevalence of allergic diseases was assessed using the Russian version of the ISAAC questionnaire. Results. According to questionnaire the prevalence of current asthma-like symptoms was 11,1%, current allergic rhinoconjunctivitis - 7,5%, current atopic dermatitis -12,3%. Out of 3205 children asthma was diagnosed in 0,9%, allergic rhinoconjunctivitis - in 3%, atopic dermatitis - in 7,9%. Family history of allergic diseases increases risk of development of the current asthma-like symptoms twice (OR=2,11; 95% CI=1,66-2,68), current allergic rhinoconjunctivitis by 2,8 times (OR=2,85; 95% CI=2,16-3,75), current atopic dermatitis by 4,6 times (OR=4,62; 95% CI=3,69-5,77). The male sex increases risk of the development of current asthma-like symptoms by 2,6 times (OR=2,63; 95% CI=1,17-5,93), current allergic rhinoconjunctivitis by 1,3 times (OR=1,35; 95% CI=1,03-1,76), smoking of parents on the first year of life of the child increases risk of development of current asthma-like symptoms by 1,6 times (OR=1,61; 95% CI=1,15-2,24), breastfeeding duration less than 6 months increases the risk of development of current atopic dermatitis by 1,6 times (OR=1,62; 95% CI=1,26-2,09; p


2019 ◽  
Vol 12 (2) ◽  
pp. 89
Author(s):  
Suri Dwi Lesmana ◽  
Deon Pradana Putra ◽  
Alida Widiawaty

House dust mite have an important role as an allergens in allergic diseases such as atopic dermatitis. Atopic dermatitisis inflammation of the skin with itching, chronic and recurrent symptoms. The aim of this study was to find out thedescription of house dust mites in the house of patients at Petala Bumi Hospital. Design of study was a crosssectional.This study was occured from May-June 2018 in the Laboratory of Parasitology and involved 30 atopicdermatitis patients with consecutive sampling technique. Results is showed 100% of atopic dermatitis patients housewere positive for house dust mites, 63.3% of patients behaved badly in hygiene which affected degree of house dustmite spread. Conclusions of this study showed that a whole place of atopic dermatitis patients house was positive forhouse dust mite, most of patients behaved badly in hygiene which affected degree of house dust mite spread.


2018 ◽  
Vol 17 (3) ◽  
pp. 236-243
Author(s):  
Natalia V. Shakhova ◽  
Elena M. Kamaltynova ◽  
Yuriy Ph. Lobanov ◽  
Tatyana S. Ardatova

Background.It is necessary to study the prevalence and risk factors of allergic rhinitis (AR) among pre-school children in order to develop a disease prevention strategy.Objective.Our aim was to study the prevalence, clinical and allergological features, and risk factors for AR in pre-school children living in urban settings of the Altai Region.Methods.At the screening stage, the study enrolled children aged 3–6 years attending pre-school educational institutions in 5 cities of the Altai Region. AR symptoms were determined using the ISAAC questionnaire. The AR was diagnosed if ≥ 2 symptoms (rhinorrhea, nasal breathing difficulty, itching in the nasal cavity, repetitive sneezing) lasted ≥ 1 h with a positive prick test and/or a blood level of specific IgE > 0.35 kU/L to at least one allergen (total 11).Results.The prevalence of AR in urban children aged 3–6 years (n = 3,205) was 10.6%; 48% of them were previously diagnosed with AR. 85% of children had a persistent course of the disease; 69% had mild AR. Most often, there was established sensitization to house dust mites (61.6%), birch pollen (40.9%), and cat fur (19.4%). The risk factors for AR were family history of allergies [odds ratio (OR) 4.2; 95% confidence interval (CI) 3.5–5.9], masculine (OR 2.8, 95% CI 1.9–4.0), smoking parents (OR 1.8, 95% CI 1.2–2.9), nonadherence to a regimen/dosage of vitamin D3 intake in infancy (OR 1.8, 95% CI 1.2–2.8), presence of asthma-like symptoms (OR 10.2, 95% CI 7.2–14.5), and manifestations of atopic dermatitis (OR 6.0, 95% CI 4.2–8.5).Conclusion.AR occurs in every tenth pre-school child (mainly of mild severity and persistent course), every second disease among them was diagnosed for the first time. Sensitization occurs to typical for childhood allergens. The risk factors for AR are family history of allergies, masculine, passive smoking, ignoring the recommendations of taking vitamin D3 in infancy, the presence of atopic dermatitis, and asthma-like symptoms.


Dermatitis ◽  
2002 ◽  
Vol 13 (2) ◽  
pp. 80-82
Author(s):  
Vincent Beltrani ◽  
Jon Hanifin

Allergy ◽  
1970 ◽  
Vol 25 (1) ◽  
pp. 41-47 ◽  
Author(s):  
MILHIM ALANI ◽  
NIELS HJORTH

2007 ◽  
Vol 158 (3) ◽  
pp. 539-543 ◽  
Author(s):  
D.G. Peroni ◽  
G.L. Piacentini ◽  
A. Bodini ◽  
E. Rigotti ◽  
R. Pigozzi ◽  
...  

2006 ◽  
Vol 54 (3) ◽  
pp. 353-366 ◽  
Author(s):  
Noémi Tarpataki ◽  
Kinga Pápa ◽  
J. Reiczigel ◽  
P. Vajdovich ◽  
K. Vörös

Medical records of 600 dogs diagnosed with atopic dermatitis were reviewed and evaluated with reference to history, geographical distribution, breed predilection, clinical signs and positive reactions to allergens as determined by intradermal skin testing (IDT) manufactured by Artuvetrin Laboratories**. In 66.6% of dogs, the age of onset of atopic dermatitis was between 4 months and 3 years. Dogs living in the garden suburb of Budapest were more sensitive to house dust mites, fleas and moulds, and dogs from the western part of Hungary were more sensitive to weeds than to other allergens (p < 0.01). Positive reactions were most common to Dermatophagoides farinae followed by human dander. The breed distribution found in the present study was consistent with that reported in the literature, except for the breeds Hungarian Vizsla, Pumi, French bulldog, Doberman Pinscher and Bobtail which were over-represented among atopic dogs compared to the breed distribution of the general dog population of a large city in Hungary. Breeds with verified adverse reaction to food were Cocker spaniels, French bulldogs, Bullmastiffs, Bull terriers, St. Bernards, Tervurens, West Highland White terriers and American Staffordshire terriers (p < 0.05). The clinical signs of atopic dermatitis and their occurrence are in accordance with the data described in the literature.


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