scholarly journals THE ROLE OF STAPHYLOCOCCUS AUREUS IN NASAL POLYPOSIS

2013 ◽  
Vol 10 (6) ◽  
pp. 5-8
Author(s):  
G P Bondareva ◽  
A B Turovsky ◽  
O V Semkina

Nasal polyposis is associated with colonization of S. aureus, which secretes enterotoxine that acts as superantigen and induces formation of monoclonal IgE by analogy with severe eosinophilic inflammation. This article describes the current insights of features of inflammation caused by S. aureus. Further research aimed at a deeper study of the role of S. aureus in pathogenesis of nasal polyposis, as well as new methods of treatment that would prevent the recurrence of the disease and improve quality of life of the patients are needed.

Pteridines ◽  
2018 ◽  
Vol 29 (1) ◽  
pp. 124-163 ◽  
Author(s):  
Hina Makkar ◽  
Mark A. Reynolds ◽  
Abhishek Wadhawan ◽  
Aline Dagdag ◽  
Anwar T. Merchant ◽  
...  

AbstractPrevious evidence connects periodontal disease, a modifiable condition affecting a majority of Americans, with metabolic and cardiovascular morbidity and mortality. This review focuses on the likely mediation of these associations by immune activation and their potential interactions with mental illness. Future longitudinal, and ideally interventional studies, should focus on reciprocal interactions and cascading effects, as well as points for effective preventative and therapeutic interventions across diagnostic domains to reduce morbidity, mortality and improve quality of life.


Author(s):  
Yu. P. Mansur ◽  
◽  
D.V. Verstakov ◽  
L.N. Scherbakov ◽  
◽  
...  

n recent years, Russia has seen an increase in the incidence of malignant tumors of the mouth and throat, including tongue cancer. Surgical methods of treatment of cancer of such localization have a crippling character and inevitably lead to disruption of a number of vital functions, including the development of tooth-jaw deformities, which further deteriorates the quality of life of such patients. Timely prescription of orthodontic devices for prophylactic and therapeutic purposes allows to prevent the development of tooth jaw abnormalities and deformities, as well as to treat the already developed pathology.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Marini ◽  
A Masini ◽  
P Maietta Latessa ◽  
T Sanna ◽  
A Raggi ◽  
...  

Abstract Background Osteoporosis is a major health burden worldwide and require a multi-modal approach including exercise. Fractures have a substantial impact on quality of life (QoL) so exercise programs may to be conducted by trainers able to deal with this condition, because exercise alone, even if in the right dosage, seems to be not enough to improve QoL. A quasi-experimental pilot study performed to determine the feasibility and safety of an Adapted Physical Activity (APA) protocol specifically designed for osteoporotic women with vertebral fractures and its effect on QoL, with a specific focus on trainer's role. Methods The Experimental Group (EG) performed APA protocol 1hour twice a week for 6 months, while the Control Group (CG) received standard care. QoL was assessed at baseline and follow-up with ECOS-16 questionnaire and semi structured interviews to understand women perceptions regarding trainer's role. Using mixed-methods quantitative and qualitative data were analyzed using SPSS 5 and NVivo 12, respectively. Results 40 post-menopausal women (mean age: 67.6±4.6) divided in 2 groups EG = 22 and CG = 18, completed the study. At follow-up, EG improved significantly QoL (EG: -0.5±0.5 vs CG: 0.0±0.3 p = 0.02). The APA intervention had a significant effect on all the components of QoL, as measured by the disease-specific ECOS-16 questionnaire: Physical Component Summary (PCS) (EG: -0.4±0.5 vs CG: 0.0±0.4 p = 0.06) and Mental Component Summary (MCS) (EG: -0.5±0.6 vs CG: 0.1±0.5 p = 0.02). The interviews confirmed this result, emphasizing the key role of the trainer in improving their QoL. The adherence calculated as number of sessions performed compared to the sessions proposed was 75.8%. No injuries were observed. Conclusions The feasibility, the safety, and the positive effect of the proposed exercise protocol on QoL confirmed also by the interviews, show that principles of exercise education applied by trainers should be extended also to patients with other chronic condition. Key messages Trainers specifically educated, could be a means of achieving the goal improving people’s QoL, as they occupy the role of exercise experts and also an educational, relational and support role. The management of osteoporosis is multi-modal and includes exercise, often recommended as a beneficial non-pharmacological treatment to slow the rate of bone loss and improve quality of life.


2022 ◽  
pp. 12-16
Author(s):  
Y. A. Kandrashkina ◽  
E. A. Orlova ◽  
A. A. Pribytkov

Atopic dermatitis is a chronic hereditary recurrent skin disease. One of the most pronounced symptoms of this dermatosis is itchy skin. Pruritus accompanies atopic dermatitis in more than 80% of cases. This review presents modern data on the mechanisms of pruritus formation in atopic dermatitis. The issues of etiological factors, neuroimmune interactions, peculiarities of skin dysfunction, as well as the role of stress are considered. The relevance of studying the topic is due to the high prevalence of atopic dermatitis among the population, a decrease in the quality of life and the lack of effective therapy. Analysis of the literature indicates the need for a comprehensive assessment of the pathogenetic mechanisms of the development of pruritus in atopic dermatitis. A more in-depth study of the mechanisms of neurogenic inflammation in atopic dermatitis will contribute to the development of new methods of diagnosis and treatment.


2017 ◽  
Vol 87 (2) ◽  
pp. 184-200 ◽  
Author(s):  
Ana Belen Navarro-Prados ◽  
Sara Serrate-Gonzalez ◽  
Jose-Manuel Muñoz-Rodríguez ◽  
Unai Díaz-Orueta

Personality traits of older adults and their contribution to life satisfaction and generative interest were assessed. A total of 342 older participants (66% women), mean age = 67.89 years old ( SD = 6.52, range = 55–84 years old), who attended the University of the Experience in Salamanca (Spain), were evaluated. Information on sociodemographic data, perceived health and activity, personality traits, generativity, and life satisfaction was collected using self-reported questionnaires. Results confirmed a relation between personality traits, life satisfaction, and generativity. In addition, generative concern, neuroticism, extraversion, agreeableness, and conscientiousness predicted life satisfaction at this stage. Moreover, the role of personality on generativity was confirmed. Individuals with interest and agreeableness toward others, who are organized, persistent, and motivated, are more predisposed to generativity. These results open the way to develop intervention programs that enhance positive personality traits and generative interest to improve quality of life of older people.


2017 ◽  
pp. 99-102
Author(s):  
S. K. Lozovik ◽  
T. A. Latoho ◽  
L. A. Hmylko

Crohn's disease is a chronic disease which is characterized by severe progressive course, worsens the quality of life, leads to disability at a young age, which requires the development of new methods of treatment and introduction of modern highly effective medicines into practical health care. This article describes a case when infliximab was applied for the first time in the treatment of a patient with Crohn's disease in the Children's Gastroenterology Department of Gomel Regional Specialized Clinical Hospital.


2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 1335.1-1335
Author(s):  
M. Saifridova ◽  
M. Vranova ◽  
L. Linkova ◽  
S. Sebkova ◽  
J. Belacek ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
R. Masekela ◽  
R. J. Green

Non-cystic fibrosis-related bronchiectasis is a chronic inflammatory lung disease, which is regarded as an “orphan” lung disease, with little research devoted to the study of this condition. Bronchiectasis results in impaired quality of life and mortality if left untreated. The tools available in the armamentarium for the management of bronchiectasis entail antibiotic therapy traditionally used to treat exacerbations, stratagems to improve mucociliary clearance, and avoidance of toxins. Macrolides have been known for the last two decades to have not only anti-bacterial effects but immunomodulatory properties as well. In cystic fibrosis, the use of macrolides is well documented in subjects colonized withPseudomonas aeruginosa, to improve quality of life and lung function. There is currently emerging evidence to suggest the benefit of macrolides in subjects not colonized withPseudomonas aeruginosa. This beneficial effect has been less explored in the context of bronchiectasis from other causes. The purpose of this paper is to review the current literature on the use of macrolides in non-cystic fibrosis related bronchiectasis in paediatrics.


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