scholarly journals Atopic dermatitis. When and how to use topical corticosteroiods?

2012 ◽  
Vol 9 (3) ◽  
pp. 32-36
Author(s):  
E S Fedenko
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Topical Treatment ◽  
Negative Impact ◽  
Mechanisms Of Action ◽  
Topical Steroids ◽  
Proper Selection ◽  
The World ◽  
Selection Of

Atopic dermatitis is a disease characterized with increasing prevalence around the world. It has chronic relapsing course and has a negative impact on the quality of life. Topical steroids (TS) due to their mechanisms of action remain the mainstay of topical treatment for AD patients. At the same time, well known side effects associated with corticosteroid therapy, although seen more frequently with incorrect TS use, and rare with the use of modern TS, in some instances limit their use. That is a reason for proper selection of topical treatment algorythms of AD including emollients and other medications in addition to the TS.

scholarly journals Pharmacotherapy of Inflammatory and Pruritic Manifestations of Corticosteroid-Responsive Dermatoses Focus on Clobetasol Propionate

2010 ◽  
Vol 2 ◽  
pp. CMT.S1993 ◽  
Author(s):  
Anna Zampetti ◽  
Claudio Feliciani ◽  
Antonello Tulli ◽  
Pierluigi Amerio
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Safety Profile ◽  
Topical Treatment ◽  
Clobetasol Propionate ◽  
Topical Steroids ◽  
Efficacy And Safety ◽  
Short Term ◽  
Chronic Eczema

Clobetasol-17 propionate is a dihalogenated corticosteroid which, on the basis of the vasoconstrictor assay, is classified as the most potent of all topical steroids. Since 1973 it has been marketed specifically for the short term topical treatment of moderate and severe cortico-responsive dermatoses for its antinflammatory, immunosuppressive and antimitotic effects. Psoriasis, atopic dermatitis, chronic eczema, boullous disorders and itching dermatosis of the genital area are usually well controlled by clobetasol with a great improvement of quality of life in patients. In this manuscript, we reviewed data concerning pharmacology, efficacy and safety profile of clobetasol-17 proprionate, updated studies on its use, efficacy of different formulations and impact on quality of life in corticosteroid-responsive dermatoses.

scholarly journals Selection of individual nutrition for patients with torpid course of atopic dermatitis

2020 ◽  
pp. 107-108
Author(s):  
Н.О. Артемьева ◽  
Е.В. Свечникова ◽  
Ю.В. Максимова ◽  
В.Н. Максимов
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Inflammatory Disease ◽  
Skin Diseases ◽  
Disease Development ◽  
Physical Discomfort ◽  
Selection Of

Атопический дерматит (АД) - это воспалительное заболевание кожи, мультифакториальной или моногенный природы, характеризующееся зудом, хроническим рецидивирующим течением и возрастными особенностями локализации и морфологии очагов поражения. Доля заболевания в структуре кожных болезней в настоящее время составляет от 10 до 30%. Когда процесс приобретает упорное течение с невыраженным эффектом от проводимой терапии и обострениями процесса до 3-4 в год с увеличением их длительности, то становится вялотекущим (торпидным). Торпидное течение АД приводит больного к снижению качества жизни за счёт физического дискомфорта и эмоциональной дезадаптации. Подходы к лечению в теории зависят от механизма развития заболевания. Atopic dermatitis (AD) is an inherited inflammatory disease of skin, multifactor or monogenic nature, characterized by itching, chronic recurrent current and age-specific features of localisation and morphology of lesion centers. The proportion of the disease in the structure of skin diseases is currently between 10 and 30%. When the process acquires a persistent course with an unparalleled effect from the performed therapy and exacerbations of the process up to 3-4 per year with increase of their duration, it becomes sluggish (torpedo) [1, 3]. The torpedo course of AD leads the patient to a decrease in the quality of life due to physical discomfort and emotional disadaptation. Approaches to treatment in theory depend on the mechanism of disease development.

scholarly journals Social isolation and quarantine in the COVID-19 pandemic: impacts on mental health and quality of population life

2021 ◽  
Vol 10 (2) ◽  
pp. e30510212535
Author(s):  
Gabriel Kiaro Leite Nunes ◽  
Karinne Alice Santos de Araújo ◽  
Thais Ranielle Souza de Oliveira ◽  
Marcelina da Conceição Botelho Teixeira ◽  
Ieler Ferreira Ribeiro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Social Isolation ◽  
Negative Impact ◽  
Definitive Treatment ◽  
World Population ◽  
The World ◽  
The Face ◽  
The Impact

The COVID-19 pandemic brought about major changes in the lifestyle of the world population. Due to the lack of vaccines or a definitive treatment for disease, governments around the world have adopted social isolation and quarantine as methods to control the spread of the virus. Objective: Thus, the objective of this study was to discuss how social isolation and quarantine periods affected people's mental health and quality of life during the COVID-19 pandemic. Methods: An integrative literature review was carried out during the COVID-19 pandemic between March and September 2020, establishing the following guiding question: How did social isolation and quarantine affect the mental health and quality of life of the population in the COVID-19 pandemic? Results: The final sample consisted of nineteen (19) articles, two (2) addressed depression during the pandemic period, three (3) presented the pandemic and the relationship with sociodemographic aspects, five (5) analyzed mental health in the pandemic, four (4) reported the impact of COVID-19 on the population's style and quality of life and the last five (5) demonstrated the quality of human relationships and emotional aspects in the face of the pandemic. Conclusion: It was demonstrated that isolation and the quarantine period had a negative impact on the population's quality of life and long-term mental health.

scholarly journals Assessment the quality of life in patients with heart failure in Asia: A scoping review

2021 ◽  
Vol 8 (2) ◽  
Author(s):  
Nurlaeli Qadrianti ◽  
Kusrini S. Kadar ◽  
Elly L. Sjattar
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Scoping Review ◽  
Inclusion Criteria ◽  
Eligibility Criteria ◽  
Patients With Heart Failure ◽  
The World ◽  
Epidemiological Characteristics ◽  
Selection Of

The prevalence of heart failure is high. More than 23 million patients worldwide and is believed to continue to increase to 46% in 2030. In America, the prevalence of heart failure is around 6 million patients per year. Meanwhile, heart failure in Asia is the highest in the world. To identify instruments for assessing patients with heart failure that used in Asia. This is a scoping review that follows the methodology of Arksey and O'Malley. We use 6 databases, namely Proquest, PubMed, EBSCO, Science Direct, ClinicalKey For Nursing, and Garuda. Articles in English and Indonesian were published between 2015 and 2020. We also did additional searches that met the inclusion criteria. Based on duplication, 2037 articles were left, then 1981 articles were screened. Then, 56 full-text articles were selected in the eligibility criteria, and the last 29 articles were selected for the synthesis. A total of 6 instruments were identified. We discussed the method, domain, and duration of assessments. The selection of instruments needs to be adapted to the epidemiological characteristics of the population. Keywords: quality of life; heart failure; scoping review; nursing care

scholarly journals Differences in Multi-Faceted Lifestyles in Response to the COVID-19 Pandemic and Their Association with Depression and Quality of Life of Older Adults in South Korea: A Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4124
Author(s):  
Kang-Hyun Park ◽  
Ah-Ram Kim ◽  
Min-Ah Yang ◽  
Ji-Hyuk Park
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
South Korea ◽  
Negative Impact ◽  
World Health ◽  
Cross Sectional ◽  
Significant Difference ◽  
The World ◽  
The Impact

Background: The World Health Organization declared COVID-19 a global pandemic on 11 March 2020, due to the number of newly reported confirmed cases and the rapid increase in deaths. Therefore, countries around the world limited their population to policies such as “social distancing” or “staying at home” to prevent the spread of the virus. The purpose of this study was to evaluate differences in lifestyle pre and post the outbreak COVID-19 among older adults in South Korea and to identify the impact of lifestyle differences on depression and quality of life. Methods: An online single questionnaire covering sociodemographic data, lifestyle details, depression status, and quality of life level was distributed using mailing lists and social media. To assess lifestyles differences in older people pre and post the outbreak of COVID-19 pandemic, the online single questionnaire was used post COVID-19 pandemic. Based on the participants’ memories, they responded lifestyles at two time points (pre and post COVID-19 pandemic). Results: The results showed that there was a significant decrease in physical activity and activity participation during the pandemic. In terms of nutrition, there was no statistically significant change pre and post the outbreak COVID-19, except for the intake of protein, fat, and vitamins. Additionally, the results showed that the resulting lifestyle differences seem to have had a negative impact on depression and quality of life among older adults in South Korea. Conclusion: There was a significant difference the lifestyle patterns among the participants in South Korea between the current period and pre COVID-19 pandemic. Additionally, it is observed that these differenced lifestyles were associated with depression and quality of life among the participants. Our findings may help to develop public health programs that support healthy lifestyles in pandemic conditions.

scholarly journals Qualidade de vida em cuidadores de menores com dermatite atópica

2020 ◽  
Vol 10 (32) ◽  
pp. 175-182
Author(s):  
Angela Rita Marçano Affonso ◽  
Cassia Cristina Venci Gonzales ◽  
Neusa Falbo Wandalsen
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
World Health Organization ◽  
Children And Adolescents ◽  
World Health ◽  
Calidad De Vida ◽  
The World ◽  
Health Organization ◽  
The Impact

O principal objetivo desse estudo foi avaliar o impacto da dermatite atópica (DA) na qualidade de vida (QV) de cuidadores de crianças e adolescentes menores de 18 anos, com esse diagnóstico, acompanhados no município de Santo André, estes foram selecionados durante as consultas, sendo registrados dados gerais e sobre a doença, e aplicado o questionário, The World Health Organization instrument to evaluate quality of life - WHOQOL-BREF aos cuidadores. Para a análise estatística, foram utilizadas as variáveis qualitativas descritas por frequências absolutas e relativas. Os dados mostram um comprometimento da QV dos cuidadores das crianças e adolescentes com DA, quando comparada à de cuidadores de controles sadios, especialmente nos domínios físico, psicológico e de relações sociais. A presença da DA afeta a QV da família conduzindo a um alto grau de comprometimento da dinâmica familiar.Descritores: Dermatite Atópica, Qualidade de Vida, Pais, Cuidadores. Quality of life in caregivers of minors with atopic dermatitisAbstract: The main objective of this study was to assess the impact of atopic dermatitis (AD) on the quality of life (QOL) of caregivers of children and adolescents under 18, followed up in the municipality of Santo André. They were selected during consultations, being recorded general and disease data, and the questionnaire, The World Health Organization instrument to evaluate quality of life - WHOQOL-BREF, was applied to caregivers. For the statistical analysis, the qualitative variables described by absolute and relative frequencies were used. The data show a compromise in the QoL of caregivers of children and adolescents with AD, when compared to that of caregivers of healthy controls, especially in the physical, psychological and social relations domains. The presence of AD affects the family's QOL leading to a high degree of impairment of family dynamics.Descriptors: Atopic Dermatitis, Quality of Life, Parents, Caregivers. Calidad de vida en cuidadores de menores con dermatitis atópicaResumen: El objetivo principal de este estudio fue evaluar el impacto de la dermatitis aopica (DA) en la calidad de vida (CV) de los cuidadores de niños y adolescentes menores de 18 años, con este diagnóstico, seguido en el municipio de Santo André, fueron seleccionados durante las consultas. Se registraron datos generales y de enfermedades, y se aplicó el cuestionario, El instrumento de la Organización Mundial de la Salud para evaluar la calidad de vida - WHOQOL-BREF, a los cuidadores. Para el análisis estadístico, se utilizaron las variables cualitativas descritas por frecuencias absolutas y relativas. Los datos muestran un compromiso en la calidad de vida de los cuidadores de niños y adolescentes con EA, en comparación con la de los cuidadores de controles sanos, especialmente en los dominios de las relaciones físicas, psicológicas y sociales. La presencia de EA afecta la calidad de vida de la familia, lo que lleva a un alto grado de deterioro de la dinámica familiar.Descriptores: Dermatitis Atópica, Calidad de Vida, Padres, Cuidadores.

scholarly journals METHODICAL APPROACHES TO THE ASSESSMENT OF THE QUALITY OF LIFE OF THE POPULATION OF THE WORLD COUNTRIES AND WAYS OF IMPROVING THE QUALITY OF LIFE INDICATORS OF THE POPULATION FOR UKRAINE

2021 ◽  
pp. 49-58
Author(s):  
N. O. Nebaba ◽  
◽  
H. Y. Bohorodytska ◽  
I. A. Maliuta ◽  
M. V. Tretiak ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Positive Impact ◽  
Civil Liberties ◽  
Pollution Index ◽  
Climate Index ◽  
Life Expectancy At Birth ◽  
The World ◽  
Quality Of Life Index

In the article the principles of improving the quality of life of the population of Ukraine were analyzed, a method of calculating the quality of life of the population of the world was developed. The solution of the tasks was carried out with the use of general scientific research methods: abstraction, analysis and synthesis, generalization, formalization, as well as special methods of analysis: structural, statistical, logical. The authors have analyzed the state of factors influencing the quality of life of the population of Ukraine: purchasing power index, safety index, health care index, cost of living index, property price to income ratio, traffic commute time index, pollution index, climate index, GDP by PPP per capita in international dollars, rating of political and civil liberties, life expectancy at birth, unemployment rate, gender equality index. General recommendations for improving the condition of these factors and priority areas have been identified. The general approaches to development of methods of calculation of quality of life of the population of the world countries are defined. A method for calculating the quality of life of the population has been developed: 5 indicators that have a positive impact on the quality of life and 5 indicators that have a negative impact on the quality of life of the population have been identified; mentioned weights of each of these indicators. The Index of Quality of Life of the Population of Ukraine, neighboring countries and developed world countries was calculated according to the developed calculation method, the obtained results have been compared with the Numbeo Quality of Life Index.

scholarly journals Quality of Life and Characterization of Patients With Atopic Dermatitis in Portugal: The QUADEP Study

2020 ◽  
Vol 30 (6) ◽  
pp. 430-438 ◽  
Author(s):  
D Carvalho ◽  
P Aguiar ◽  
P Mendes-Bastos ◽  
A Palma-Carlos ◽  
J Freitas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Negative Impact ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Impact Scale ◽  
Study Population ◽  
The Impact

Objectives: To investigate the quality of life (QOL) of and to characterize patients with atopic dermatitis (AD) in Portugal. Methods: This was a cross-sectional study of patients with AD and other eczemas. Skindex-29, Skindex-teen, and the Childhood Atopic Dermatitis Impact Scale (CADIS) were the instruments used to assess QOL in adults, teenagers, and children, respectively. The SF-12 was also used, and disease severity was evaluated using the Patient-Oriented SCORAD (PO-SCORAD) instrument. Associations with QOL were assessed based on the odds ratio (OR). P values <.05 and 95%CIs were considered statistically significant. Results: The study population comprised 162 participants aged 0.5-74 years. We found that 37.3% of AD patients consider their disease disabling and that more than half of the patients feel stigmatized by society. The mean Skindex score for AD was 39.68, and the impact on QOL was severe in 44%. “Symptoms” was the most affected category in adults. AD was moderate to severe in 87% of the sample. One of the factors that most influenced poorer QOL in AD was age: with increasing age, the Skindex is likely to increase (OR, 1.03; 95%CI, 1.00-1.06). “Considering the disease a disability” was also associated (OR, 6.72; 95%CI, 2.56-17.63). QOL worsens with increasingly affected body area (OR, 1.07; 95%CI, 1.03-1.11) and the presence of edema (OR, 2.0; 95%CI, 1.23-3.40). Conclusions: This is the first study to provide data on QOL in patients with AD in Portugal. Our data show an expected negative impact. More awareness-raising activities are needed to increase knowledge, decrease stigmatization, and, consequently, address the factors involved in the QOL of patients with AD.

Zinc and Probiotic Therapy for Management of Hepatic Encephalopathy

2020 ◽  
Vol 35 (4) ◽  
pp. 171-175
Author(s):  
Alessa D. Gonzales ◽  
Justin P. Reinert
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Clinical Trials ◽  
Hepatic Encephalopathy ◽  
Negative Impact ◽  
Standard Of Care ◽  
Mechanisms Of Action ◽  
Tolerability Profile ◽  
Decompensated Liver Disease

Hepatic encephalopathy is a complication of decompensated liver disease that consumes considerable health care resources and has a negative impact on quality of life. For several decades, maintenance therapy with lactulose has been considered the standard of care, but emerging data from clinical trials demonstrate that other therapeutic options may be available and could have a better tolerability profile than lactulose. This brief review will discuss the pathophysiology of hepatic encephalopathy and proposed mechanisms of action of zinc and probiotics in this context, discussing the findings of key trials.

Zinc and Probiotic Therapy for Management of Hepatic Encephalopathy

2020 ◽  
Vol 35 (4) ◽  
pp. 171-175
Author(s):  
Alessa D. Gonzales ◽  
Justin P. Reinert
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Clinical Trials ◽  
Hepatic Encephalopathy ◽  
Negative Impact ◽  
Standard Of Care ◽  
Mechanisms Of Action ◽  
Tolerability Profile ◽  
Decompensated Liver Disease

Hepatic encephalopathy is a complication of decompensated liver disease that consumes considerable health care resources and has a negative impact on quality of life. For several decades, maintenance therapy with lactulose has been considered the standard of care, but emerging data from clinical trials demonstrate that other therapeutic options may be available and could have a better tolerability profile than lactulose. This brief review will discuss the pathophysiology of hepatic encephalopathy and proposed mechanisms of action of zinc and probiotics in this context, discussing the findings of key trials.

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