scholarly journals THE INVESTIGATION OF TECHNOLOGICAL AND PHYSICO-CHEMICAL CHARACTERISTICS OF ACTIVE SUBSTANCES AND THEIR GRANULATES FOR THE DEVELOPMENT COMBINED DRUG “ANALPHENON”

2020 ◽  
pp. 34-37
Author(s):  
Yunusova Kholida Mannanovna ◽  
Ravshanova Sevara Ergashevna
Keyword(s):  
Key Words ◽  
Therapeutic Effect ◽  
Fractional Composition ◽  
Chemical Characteristics ◽  
Technological Properties ◽  
High Quality ◽  
Physico Chemical ◽  
Active Substances

In order to theoretically substantiate the composition and technology of “Analfenon” capsules, we have studied the basic physicochemical and technological properties of samples of substance and granulates. These properties are interrelated and in a certain way can affect the process of obtaining high-quality capsules with the necessary therapeutic effect. Substance — powder and masses for encapsulation — was subjected to physico-chemical and pharmacotechnological research. The results will serve as the basis for our further research on the development of capsule technology "Analfenon" a. KEY WORDS: capsule, technological properties, fractional composition.

scholarly journals Research of technological properties of bread made with the addition of beet kvass

2021 ◽  
Vol 23 (96) ◽  
pp. 3-7
Author(s):  
H. Karpyk ◽  
M. Kukhtyn ◽  
V. Selskyi ◽  
I. Nazarko ◽  
O. Pokotylo ◽  
...  
Keyword(s):  
Healthy Eating ◽  
Rapid Development ◽  
Bakery Products ◽  
Technological Properties ◽  
Drying Process ◽  
High Quality ◽  
Physico Chemical ◽  
Long Time ◽  
Bread Production

The issue of healthy eating has always been relevant, especially this problem has been exacerbated by the rapid development of food technology and the production of a significant number of semi-finished products. As a result, there is a need to develop new types of food, including unleavened and low-calorie bread, bakery products enriched with vitamins, minerals, plant supplements. The aim of the work was to substantiate the technology of bread production with the use of beet kvass and to investigate the physico-chemical quality indicators of experimental samples of finished products. Technological indicators that characterize the quality of bread: moisture, porosity, crumbliness, acidity were determined by generally accepted methods. Bread made with beet kvass has been found to have well-developed crumb porosity, does not crumble for a long time, hardens slowly, and is resistant to microbiological spoilage. The crumb is not deformed and elastic when pressed. Replacing part of the water during the kneading of wheat dough with beet kvass (50 % by weight of flour) makes it possible to intensify the maturation of semi-finished products, both in traditional and accelerated technologies, to create a more complete nutrient medium for yeast activation, to obtain high quality bakery products storage. It has also been found that during the storage of bread, the hydrophilic properties of the crumb, its crumbliness changes slightly. The drying process is most intense during the first day, then slows down.

scholarly journals New Insight into the Identity of Italian Grapevine Varieties: The Case Study of Calabrian Germplasm

Agronomy ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1538
Author(s):  
Valentina Fanelli ◽  
Vincenzo Roseti ◽  
Michele Antonio Savoia ◽  
Monica Marilena Miazzi ◽  
Pasquale Venerito ◽  
...  
Keyword(s):  
Morphological Analysis ◽  
Southern Italy ◽  
Chemical Characteristics ◽  
Cultivated Land ◽  
High Quality ◽  
Wine Production ◽  
Physico Chemical ◽  
Insight Into

Calabria is a region located in Southern Italy and it is characterized by a long tradition of viticulture practices and favorable pedoclimatic conditions for grapevine cultivation. Nevertheless, less than 2% of cultivated land is dedicated to grapevine growing in Calabria. The characterization of local grapevine accessions is crucial to valorize the local and peculiar Italian products and boost the Calabrian winemaking sector. With this purpose, we performed a deep characterization of two widespread Calabrian grapevine varieties—Magliocco Dolce and Brettio Nero, of which very little is known. In particular, a genetic and morphological analysis, a berry physico-chemical and polyphenolic compositions assessment, and oenological evaluation of monovarietal wines were carried out. Our results allowed us to demonstrate that Magliocco Dolce and Brettio Nero are unique and distinct varieties with peculiar morphological and chemical characteristics and show the suitability of these two varieties in high-quality wine production. Moreover, the obtained molecular profiles will be useful for authentication and traceability purposes.

Study of the fractional composition of granulate influence on the performance indicators of tablets based on salmonellosis bacteriophag

2020 ◽  
pp. 74-77
Keyword(s):  
Performance Indicators ◽  
Fractional Composition ◽  
Pressing Pressure ◽  
Technological Properties ◽  
Compression Pressure ◽  
Plastic Properties ◽  
Technological Factors ◽  
Density Flow ◽  
Crush Strength ◽  
Quality Indexes

The author presented experimental data on the influence of technological factors on the quality indexes of tablets based on a cryoliofilized salmonella bacteriophage. The analysis of the technological properties of model granules with such parameters as bulk density, flow ability, vibration compacting index, Hausner index, Сarr's index showed that the fractional composition of the granules should contain no more than 33 % of the pulverized fraction (0,25 mm or less). The granulate, regardless of its fractional composition, has elastic-plastic properties characterizing the strength of the tablets. The influence of the pressing pressure of the cryoliofilized composition tablets with salmonella bacteriophage on the crush strength and disintegration of enteric-soluble tablets was studied. The optimum compression pressure of tablets within 60 mPa of granules with a content of pulp fraction (0.25 mm or less) is not to be higher than 33 %.

Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)

2019 ◽  
Vol 70 (7) ◽  
pp. 2534-2537
Author(s):  
Gladiola Tantaru ◽  
Mihai Apostu ◽  
Antonia Poiata ◽  
Mihai Nichifor ◽  
Nela Bibire ◽  
...  
Keyword(s):  
Schiff Base ◽  
Chemical Structure ◽  
Antimicrobial Activities ◽  
Ethylene Diamine ◽  
Chemical Characteristics ◽  
Gram Negative Bacteria ◽  
Pharmacological Effects ◽  
Physico Chemical ◽  
Anti Inflammatory ◽  
Inflammatory Effect

The paper presents the synthesis of a new complex combination of a Bis-Schiff base with Mn(II) ions with great potential for antimicrobial and anti-inflammatory activity. A new complex of the Salen-type ligand, 1-ethyl-salicylidene-bis-ethylene diamine was synthetized using Mn(II) ions. The chemical structure was confirmed through 1H-NMR and IR spectroscopy. The antimicrobial activities of the Bis-Schiff base and its complex were tested in comparison with Ampicillin, Chloramphenicol, Tetracycline, Ofloxacin and Nystatin. Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.

Progress and Prospects in Translating Nanobiotechnology in Medical Theranostics

2020 ◽  
Vol 16 (5) ◽  
pp. 685-707 ◽  
Author(s):  
Amna Batool ◽  
Farid Menaa ◽  
Bushra Uzair ◽  
Barkat Ali Khan ◽  
Bouzid Menaa
Keyword(s):  
Biological Properties ◽  
Chemical Characteristics ◽  
Intrinsic Properties ◽  
The Past ◽  
Profound Influence ◽  
Functionalized Nanomaterials ◽  
Physico Chemical ◽  
Properties Of Materials ◽  
Targeted Drug ◽  
And Performance

: The pace at which nanotheranostic technology for human disease is evolving has accelerated exponentially over the past five years. Nanotechnology is committed to utilizing the intrinsic properties of materials and structures at submicroscopic-scale measures. Indeed, there is generally a profound influence of reducing physical dimensions of particulates and devices on their physico-chemical characteristics, biological properties, and performance. The exploration of nature’s components to work effectively as nanoscaffolds or nanodevices represents a tremendous and growing interest in medicine for various applications (e.g., biosensing, tunable control and targeted drug release, tissue engineering). Several nanotheranostic approaches (i.e., diagnostic plus therapeutic using nanoscale) conferring unique features are constantly progressing and overcoming all the limitations of conventional medicines including specificity, efficacy, solubility, sensitivity, biodegradability, biocompatibility, stability, interactions at subcellular levels. : This review introduces two major aspects of nanotechnology as an innovative and challenging theranostic strategy or solution: (i) the most intriguing (bare and functionalized) nanomaterials with their respective advantages and drawbacks; (ii) the current and promising multifunctional “smart” nanodevices.

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